Expression of B7-1 costimulatory molecules in patients with multibacillary leprosy and reactional states

Clinical and Experimental Dermatology

Volumn 32, Issue 1, 2007, Pages 75-80

  Santos, D O ^a   Castro, H C ^a   Bourguignon, S C ^a   Bastos, O M ^a   Rodrigues, C R ^b   Van Heuverswyn, H ^c   Nery, J A ^d   Miranda, A ^d,e  

^a FLUMINENSE FEDERAL UNIVERSITY   (Brazil)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^c Division Biotech Incubator Partners   (Belgium)

^d INSTITUTO OSWALDO CRUZ   (Brazil)

^e STATE UNIVERSITY OF RIO DE JANEIRO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; B7 ANTIGEN; CD14 ANTIGEN; CD1B ANTIGEN; HLA DR ANTIGEN;

ANTIGEN EXPRESSION; ARTICLE; BLOOD SAMPLING; CELL ISOLATION; CONTROLLED STUDY; ERYTHEMA NODOSUM LEPROSUM; FLOW CYTOMETRY; HUMAN; HUMAN EXPERIMENT; IMMUNOHISTOCHEMISTRY; INFLAMMATORY CELL; MULTIBACILLARY LEPROSY; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; REVERSAL REACTION; SKIN BIOPSY; SKIN DEFECT; STATISTICAL ANALYSIS;

ANTIGENS, CD80; FLOW CYTOMETRY; HUMANS; IMMUNOHISTOCHEMISTRY; LEPROSY, LEPROMATOUS; LEUKOCYTES, MONONUCLEAR;

EID: 33845913256     PISSN: 03076938     EISSN: 13652230     Source Type: Journal    
DOI: 10.1111/j.1365-2230.2006.02291.x     Document Type: Article

References (25)

1. World Health Organization. Leprosy - global situation. Wkly Epidemiol Rec 2000; 75: 225-32.
2. Santos DO, Santos SL, Esquenazi D et al. Evaluation of B7-1 (CD80) and B7-2 (CD86) costimulatory molecules and dendritic cells on the immune response in leprosy. Japan J Lepr 2001; 70: 15-24.
3. Hashimoto K, Maeda Y, Kimura H, Suzuki K et al. Mycobacterium leprae infection in monocyte-derived dendritic cells and its influence on antigen-presenting function. Infect Immun 2002; 70: 5167-76.
4. Cheadle EJ, Selby PJ, Jackson AM. Mycobacterium bovis bacillus Calmette-Guérin-infected dendritic cells potently activate autologous T cells via a B7 and interleukin-12-dependent mechanism. Immunol 2003; 108: 79-88.
5. Sieling PA, Jullien D, Dahlem M et al. CD1 expression by dendritic cellsin human leprosy lesions: correlation with effective host immunity. J Immunol 1999; 162: 1851-8.
6. Santos DO, Suffys PN, Bonifácio K et al. In vitro tumor necrosis factor production by mononuclear cells from lepromatous leprosy patients and from patients with erythema nodosum leprosum. Clin Immunol Immunopathol 1993; 67: 199-203.
7. Moraes MO, Sarno EN, Almeida AS. Cytokine mRNA expression in leprosy reaction: a possible role for IFN-γ and IL-12 in reactions (RR and ENL). Scand J Immunol 1999; 50: 541-9.
8. Kaplan G, Cohn ZA. Regulation of cell-mediated immunity in lepromatous leprosy. Lepr Rev 1986; 57: 199-202.
9. Lenschow D, Bluestone JÁ. CD28 / B7 system of T cell costimulation. Annu Rev Immunol 1996; 14: 233-58.
10. Ridley DS, Joplin WH. Classification of leprosy according to immunity: a five group system. Int J Lepr 1966; 34: 255-63.
11. Santos DO, Suffys P, Bonifácio K et al. Evaluation of chemiluminescence, procoagulant activity and antigen presentation by monocytes from lepromatous leprosy patients with or without reactional episodes. Lepr Rev 1994; 65: 88-99.
12. Sampaio EP, Caneshi JR, Nery JÁ et al. Cellular immune response to Mycobacterium leprae infection in human immunodeficiency virus-infected individuals. Infect Immun 1995; 63: 1848-55.
13. Nickoloff BJ, Naidu Y. Perturbation of epidermal barrier function correlates with initiation of cytokine cascade in human skin. J Am Acad Dermatol 1994; 30: 535-46.
14. Modlin RL, Hofman FM, Taylor CR et al. T lymphocyte subsets in the skin lesions of patients with leprosy. J Am Acad Dermatol 1983; 8: 182-9.
15. Trinchieri G. Interleukin-12 and its role in the generation of Th1 cells. Immunol Today 1993; 14: 335-8.
16. Macatonia SE, Hosken NA, Litton M et al. Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cells. J Immunol 1995; 154: 5071-9.
17. Banchereau J, Briere F, Caux C et al. Immunobiology of dendritic cells. Annu Rev Immunol 2000; 18: 767-811.
18. Mittal A, Nath I. Accessory cell heterogeneity in lepromatous leprosy; dendritic cells and not monocytes support T cell responses. Clin Exp Immunol 1989; 76: 233-9.
19. Bhardwaj N, Friedman SM, Cole BC et al. Dendritic cells are potent antigen-presenting cells for microbial superantigens. J Exp Med 1992; 175: 267-73.
20. Scheicher C, Mehlig M, Dienes HP et al. Uptake of microparticle-absorbed protein antigen by bone marrow dendritic cells results in upregulation of IL-12 and IL-12, p40. / p35 and triggers prolonged efficient antigen presentation. Eur J Immunol 1995; 25: 1566-72.
21. Verghese S, Healey DG, Curtis J et al. Accessory cell function of dendritic cells from lymphonodes containing Mycobacterium leprae induced granulomas. Int Arch Allergy Appl Immunol 1988; 87: 392-9.
22. Sornasse T. Antigen-pulsed dendritic cells can efficiently induce an antibody response in vivo. J Exp Med 1992; 175: 15-20.
23. Agreawala JN. Potencial role of B7-1 in immunosuppression in leprosy. Clin Exp Immunol 1998; 111: 53-6.
24. Saha B. Macrophage - T-cell interaction in experimental mycobacterial infection. Selective regulation of costimulatory molecules on Mycobacterium infected macrophages and its implication in the suppression of cell-mediated immune response. Eur J Immunol 1994; 24: 2618-24.
25. Murphy ML, Engwerda CR, Gorak PM et al. B7-2 blockade enhances T cell responses to Leishmania donovani. J Immunol 1997; 159: 4460-6.