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Volumn 14, Issue 5-6, 2006, Pages 250-255

Leptin modulates the detrimental effect of Porphyromonas gingivalis lipopolysaccharide-induced cytosolic phospholipase A2 activation on salivary mucin synthesis via ERK-signal transduction

Author keywords

cPLA2 activation; ERK; Leptin; Mucin synthesis; P. gingivalis; PAF

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; GINKGOLIDE A; LEPTIN; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MUCIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PHOSPHOLIPASE A2; SALIVA PROTEIN; THROMBOCYTE ACTIVATING FACTOR; WORTMANNIN;

EID: 33845907662     PISSN: 09254692     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10787-006-1525-5     Document Type: Conference Paper
Times cited : (9)

References (34)
  • 1
    • 0034878831 scopus 로고    scopus 로고
    • Gastric leptin and Helicobacter pylori infection
    • Azuma, T., Suto, H., Ito, Y. et al. (2001). Gastric leptin and Helicobacter pylori infection. Gut 49, 324-9.
    • (2001) Gut , vol.49 , pp. 324-329
    • Azuma, T.1    Suto, H.2    Ito, Y.3
  • 3
    • 0032917633 scopus 로고    scopus 로고
    • Leptin deficiency enhances sensitivity to endotoxin-induced lethality
    • Faggioni, R., Fantuzzi, C., Gabay, C. et al. (1999). Leptin deficiency enhances sensitivity to endotoxin-induced lethality. Am J Physiol 276, R136-42.
    • (1999) Am J Physiol , vol.276
    • Faggioni, R.1    Fantuzzi, C.2    Gabay, C.3
  • 4
    • 0035195887 scopus 로고    scopus 로고
    • Leptin regulation of the immune responses and immunodeficiency of malnutrition
    • Faggioni, R., Feingold, K.R., Grunfeld, C. (2001). Leptin regulation of the immune responses and immunodeficiency of malnutrition. FASEB J 15, 2565-71.
    • (2001) FASEB J , vol.15 , pp. 2565-2571
    • Faggioni, R.1    Feingold, K.R.2    Grunfeld, C.3
  • 5
    • 0026824717 scopus 로고
    • New considerations in the prevalence of periodontal disease
    • Fox, C.H. (1992). New considerations in the prevalence of periodontal disease. Curr Opin Den 2, 5-11.
    • (1992) Curr Opin Den , vol.2 , pp. 5-11
    • Fox, C.H.1
  • 6
    • 17944367189 scopus 로고    scopus 로고
    • Identification of leptin in human saliva
    • Groschl, M., Rauch, M., Wagner, R. et al. (2001). Identification of leptin in human saliva. J Clin Endocrinol Metab 86, 5234-9.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 5234-5239
    • Groschl, M.1    Rauch, M.2    Wagner, R.3
  • 7
    • 0037160072 scopus 로고    scopus 로고
    • Molecular mechanisms for lipopolysaccharide-induced biphasic activation of NF-κB
    • Han, S.J., Ko, H.M., Choi, J.H. et al. (2002). Molecular mechanisms for lipopolysaccharide-induced biphasic activation of NF-κB. J Biol Chem 277, 44715-21.
    • (2002) J Biol Chem , vol.277 , pp. 44715-44721
    • Han, S.J.1    Ko, H.M.2    Choi, J.H.3
  • 8
    • 0031827918 scopus 로고    scopus 로고
    • Leptin: Its pharmacokinetics and tissue distribution
    • Hill, R.A., Margetic, S., Pegg, G.C., Gazzola, C. (1998). Leptin: its pharmacokinetics and tissue distribution. Int J Obes 22, 765-70.
    • (1998) Int J Obes , vol.22 , pp. 765-770
    • Hill, R.A.1    Margetic, S.2    Pegg, G.C.3    Gazzola, C.4
  • 10
    • 0037821691 scopus 로고    scopus 로고
    • Leptin induces apoptosis via ERK/cPLA2/cytochrome c pathway in human bone marrow stromal cells
    • Kim, G.S., Hong, J.S., Kim, S.W. et al. (2003). Leptin induces apoptosis via ERK/cPLA2/cytochrome c pathway in human bone marrow stromal cells. J Biol Chem 278, 21920-9.
    • (2003) J Biol Chem , vol.278 , pp. 21920-21929
    • Kim, G.S.1    Hong, J.S.2    Kim, S.W.3
  • 11
    • 0029031505 scopus 로고
    • Platelet-activating factor induces NF-κB activation through a G protein-coupled pathway
    • Kravchenko, V.V., Pan, Z., Han, J. et al. (1995). Platelet-activating factor induces NF-κB activation through a G protein-coupled pathway. J Biol Chem 270, 14928-34.
    • (1995) J Biol Chem , vol.270 , pp. 14928-14934
    • Kravchenko, V.V.1    Pan, Z.2    Han, J.3
  • 12
    • 0027338999 scopus 로고
    • 2 is phosphorylated and activated by MAP kinase
    • 2 is phosphorylated and activated by MAP kinase. Cell 72, 178-83.
    • (1993) Cell , vol.72 , pp. 178-183
    • Lin, L.L.1    Wartman, M.2    Lin, A.Y.3
  • 13
    • 0031965266 scopus 로고    scopus 로고
    • Leptin regulates proinflammatory immune responses
    • Loffreda, S., Yang, S.Q., Lin, H.Z. et al. (1998). Leptin regulates proinflammatory immune responses. FASEB J 12, 57-65.
    • (1998) FASEB J , vol.12 , pp. 57-65
    • Loffreda, S.1    Yang, S.Q.2    Lin, H.Z.3
  • 14
    • 0023286455 scopus 로고
    • The functions of saliva
    • Mandel, I.D. (1982). The functions of saliva. J Dent Res 66, 623-35.
    • (1982) J Dent Res , vol.66 , pp. 623-635
    • Mandel, I.D.1
  • 15
    • 13544267706 scopus 로고    scopus 로고
    • Enhanced production of leptin in gastric fundic mucosa with Helicobacter pylori infection
    • Nishi, Y., Isomoto, H., Uotani, S. et al. (2005). Enhanced production of leptin in gastric fundic mucosa with Helicobacter pylori infection. World J Gastroenterol 11, 695-9.
    • (2005) World J Gastroenterol , vol.11 , pp. 695-699
    • Nishi, Y.1    Isomoto, H.2    Uotani, S.3
  • 16
    • 0035322687 scopus 로고    scopus 로고
    • Microbiological characteristics of subgingival microbiota in adult periodontitis, localized juvenile periodontitis and rapidly progressive periodontitis subjects
    • Nonnenmacher, C., Mutters, R., deJacoby, L.F. (2001). Microbiological characteristics of subgingival microbiota in adult periodontitis, localized juvenile periodontitis and rapidly progressive periodontitis subjects. Clin Microbiol Infect 7, 213-21.
    • (2001) Clin Microbiol Infect , vol.7 , pp. 213-221
    • Nonnenmacher, C.1    Mutters, R.2    deJacoby, L.F.3
  • 17
    • 0031981250 scopus 로고    scopus 로고
    • Lipopolysaccharide a virulence factor of Helicobacter pylori: Effect of antiulcer agents
    • Piotrowski, J. (1998). Lipopolysaccharide a virulence factor of Helicobacter pylori: effect of antiulcer agents. J Physiol Pharmacol 49, 3-24.
    • (1998) J Physiol Pharmacol , vol.49 , pp. 3-24
    • Piotrowski, J.1
  • 18
    • 28244449007 scopus 로고    scopus 로고
    • 2 activation and lipid generation in lipopolysaccharide-stimulated macrophages
    • 2 activation and lipid generation in lipopolysaccharide-stimulated macrophages. J Biol Chem 280, 38969-75.
    • (2005) J Biol Chem , vol.280 , pp. 38969-38975
    • Qi, H.Y.1    Shelhamer, J.H.2
  • 20
    • 33845904703 scopus 로고    scopus 로고
    • 2 in allergic responses and parturition
    • 2 in allergic responses and parturition. Nature 390, 618-22.
    • (2000) Nature , vol.390 , pp. 618-622
    • Sapirstein, A.1    Bonventre, J.V.2
  • 22
    • 0026550980 scopus 로고
    • Platelet-activating factor receptor and signal transduction mechanism
    • Shukla, S.D. (1992). Platelet-activating factor receptor and signal transduction mechanism. FASEB J 6, 2296-302.
    • (1992) FASEB J , vol.6 , pp. 2296-2302
    • Shukla, S.D.1
  • 23
    • 0036201149 scopus 로고    scopus 로고
    • Screening and modulation of extracellular signals by mucous barrier. Serum glycosylphosphatidyl- inositol phospholipase D (GPI-PLD) releases protective mucous barrier from oral mucosa
    • Slomiany, A., Nishikawa, H., Slomiany, B.L. (2002). Screening and modulation of extracellular signals by mucous barrier. Serum glycosylphosphatidyl- inositol phospholipase D (GPI-PLD) releases protective mucous barrier from oral mucosa. J Physiol Pharmacol 53, 21-38.
    • (2002) J Physiol Pharmacol , vol.53 , pp. 21-38
    • Slomiany, A.1    Nishikawa, H.2    Slomiany, B.L.3
  • 24
    • 0027166904 scopus 로고
    • Glycosulfatase activity of Porphyromonas gingivalis, a bacterium associated with periodontal disease
    • Slomiany, B.L., Murty, V.L.N., Piotrowski, J. et al. (1993). Glycosulfatase activity of Porphyromonas gingivalis, a bacterium associated with periodontal disease. Biochem. Mol. Biol. Int. 29, 973-80.
    • (1993) Biochem. Mol. Biol. Int , vol.29 , pp. 973-980
    • Slomiany, B.L.1    Murty, V.L.N.2    Piotrowski, J.3
  • 26
    • 0036399244 scopus 로고    scopus 로고
    • Porphyromonas gingivalis lipopolysaccharide interferes with salivary mucin synthesis through inducible nitric oxide synthase activation by ERK and p38 kinase
    • Slomiany, B.L., Slomiany, A. (2002). Porphyromonas gingivalis lipopolysaccharide interferes with salivary mucin synthesis through inducible nitric oxide synthase activation by ERK and p38 kinase. Biochem Biophys Res Commun 297, 1149-53.
    • (2002) Biochem Biophys Res Commun , vol.297 , pp. 1149-1153
    • Slomiany, B.L.1    Slomiany, A.2
  • 27
    • 0344926360 scopus 로고    scopus 로고
    • Leptin suppresses Porphyromonas gingivalis lipopolysaccharide interference with salivary mucin synthesis
    • Slomiany, B.L., Slomiany, A. (2003). Leptin suppresses Porphyromonas gingivalis lipopolysaccharide interference with salivary mucin synthesis. Biochem Biophys Res Commun 312, 1099-103.
    • (2003) Biochem Biophys Res Commun , vol.312 , pp. 1099-1103
    • Slomiany, B.L.1    Slomiany, A.2
  • 28
    • 1942424869 scopus 로고    scopus 로고
    • Salivary phospholipid secretion in response to β-adrenergic stimulation is mediated by Src kinase-dependent epidermal growth factor receptor transactivation
    • Slomiany, B.L., Slomiany, A. (2004). Salivary phospholipid secretion in response to β-adrenergic stimulation is mediated by Src kinase-dependent epidermal growth factor receptor transactivation. Biochem Biophys Res Commun 318, 247-52.
    • (2004) Biochem Biophys Res Commun , vol.318 , pp. 247-252
    • Slomiany, B.L.1    Slomiany, A.2
  • 29
    • 25644459873 scopus 로고    scopus 로고
    • Endothelin-1-dependent leptin induction in gastric mucosal inflammatory responses to H. pylori lipopolysaccharide
    • Slomiany, B.L., Slomiany, A. (2005). Endothelin-1-dependent leptin induction in gastric mucosal inflammatory responses to H. pylori lipopolysaccharide. Biochem Biophys Res Commun 336, 1106-111.
    • (2005) Biochem Biophys Res Commun , vol.336 , pp. 1106-1111
    • Slomiany, B.L.1    Slomiany, A.2
  • 30
    • 33748509735 scopus 로고    scopus 로고
    • 2 activation interferes with salivary mucin synthesis via platelet-activating factor generation
    • 2 activation interferes with salivary mucin synthesis via platelet-activating factor generation. Inflammopharmacol 14, 144-9.
    • (2006) Inflammopharmacol , vol.14 , pp. 144-149
    • Slomiany, B.L.1    Slomiany, A.2
  • 31
    • 0033521601 scopus 로고    scopus 로고
    • Leptin is an endogenous protective protein against the toxicity exerted by tumor necrosis factor
    • Takahashi, N., Waelput, W., Guisez, Y. (1999). Leptin is an endogenous protective protein against the toxicity exerted by tumor necrosis factor. J Exp Med 189, 207-12.
    • (1999) J Exp Med , vol.189 , pp. 207-212
    • Takahashi, N.1    Waelput, W.2    Guisez, Y.3
  • 32
    • 0031445523 scopus 로고    scopus 로고
    • 2 in allergic responses and parturition
    • 2 in allergic responses and parturition. Nature 390, 618-22.
    • (1997) Nature , vol.390 , pp. 618-622
    • Uozumi, N.1    Kume, K.2    Nagase, T.3
  • 33
    • 0035757961 scopus 로고    scopus 로고
    • Inflammatory mediators in gastrointestinal defense and injury
    • Wallace, J.L., Ma, L. (2001). Inflammatory mediators in gastrointestinal defense and injury. Exp Biol Med 226, 1003-15.
    • (2001) Exp Biol Med , vol.226 , pp. 1003-1015
    • Wallace, J.L.1    Ma, L.2
  • 34
    • 0036073921 scopus 로고    scopus 로고
    • Porphyromonas gingivalis lipopolysaccharide signaling in gingival fibroblasts-CD14 and Toll-like receptors
    • Wang, P.L., Ohura, K. (2002). Porphyromonas gingivalis lipopolysaccharide signaling in gingival fibroblasts-CD14 and Toll-like receptors. Crit Rev Oral Biol Med 13, 132-42.
    • (2002) Crit Rev Oral Biol Med , vol.13 , pp. 132-142
    • Wang, P.L.1    Ohura, K.2


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