Pilocarpine-loaded chitosan-PAA nanosuspension for ophthalmic delivery

Journal of Biomaterials Science, Polymer Edition

Volumn 18, Issue 2, 2007, Pages 205-221

  Lin, Hong Ru ^a   Yu, Shi Ping ^a   Kuo, Chun Jung ^b   Kao, Huei Jen ^b   Lo, Yu Li ^c   Lin, Yiu Jiuan ^d  

^a SOUTHERN TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^b CHIA NAN UNIVERSITY OF PHARMACY AND SCIENCE   (Taiwan)

^c NATIONAL UNIVERSITY OF TAINAN   (Taiwan)

^d CHUNG HWA UNIVERSITY OF MEDICAL TECHNOLOGY   (Taiwan)

Author keywords

Buffer pH effect; Chitosan; Drug carrier; Nanoparticle; Pilocarpine; Poly(acrylicacid)

Indexed keywords

CONTROLLED DRUG DELIVERY; NANOSTRUCTURED MATERIALS; OPHTHALMOLOGY; PH EFFECTS; POLYACRYLATES; POLYMERIZATION; POLYSACCHARIDES;

CHITOSAN; OPTHALMIC DELIVERY; PILOCARPINE; POLYACRYLIC ACID;

BIOMATERIALS;

ARTIFICIAL TEAR; BUFFER; CHITOSAN; EYE DROPS; NANOCARRIER; PILOCARPINE; POLYACRYLIC ACID;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG RESPONSE; FEMALE; IN VITRO STUDY; IN VIVO STUDY; MALE; MOLECULAR STABILITY; MOLECULAR WEIGHT; NANOTECHNOLOGY; NONHUMAN; PARTICLE SIZE; PH; PHYSICAL CHEMISTRY; POLYMERIZATION; PRIORITY JOURNAL; PUPIL REFLEX; RABBIT; SUSPENSION; SUSTAINED DRUG RELEASE; ZETA POTENTIAL;

ACRYLIC RESINS; ANIMALS; BIOCOMPATIBLE MATERIALS; CHITOSAN; DRUG CARRIERS; FEMALE; HYDROGEN-ION CONCENTRATION; MALE; MATERIALS TESTING; MIOTICS; MOLECULAR WEIGHT; NANOPARTICLES; OPHTHALMIC SOLUTIONS; PARTICLE SIZE; PILOCARPINE; RABBITS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SUSPENSIONS;

EID: 33845899940     PISSN: 09205063     EISSN: None     Source Type: Journal    
DOI: 10.1163/156856207779116739     Document Type: Article

References (39)

1. C. L. Bourlais, L. Acar, H. Zia, P. A. Sado, T. Needham and R. Leverge, Prog. Retinal Eye Res. 17, 33 (1998).
2. J. Kreuter, in: Bioadhesive Drug Delivery System, V. Lenaerts and R. Gurny (Eds), Chapter 1, pp. 203. CRC Press, Boca Raton, FL (1990).
3. K. Zimmer and J. Kreuter, Adv. Drug Deliv. Rev. 16, 61 (1995).
4. L. Marchal-Heussler, D. Sirbat, M. Hoffman and P. Maincent, J. Fr. Ophtalmol. 14, 371 (1991).
5. L. Marchal-Heussler, H. Fessi, J. P. Devissaguet, M. Hoffman and P. Maincent, STP Pharm. Sci. 2, 98 (1992).
6. T. Harmia, P. Speiser and J. Kreuter, J. Microencapsul. 3, 3 (1986).
7. T. Harmia, P. Speiser and J. Kreuter, Pharm. Acta Helv. 62, 322 (1986).
8. A. M. Durrani, S. J. Farr and I. W. Kellaway, J. Pharm. Pharmacol. 47, 581 (1995).
9. I. Genta, B. Conti, P. Prugini, F. Pavanetto, A. Spadaro and P. Puglisi, J. Pharm. Pharmacol. 49, 737 (1997).
10. A. M. De Campos, A. Sanchez and M. J. Alonso, Int. J. Pharm. 224, 159 (2001).
11. L. Brannon-Peppas, Int. J. Pharm. 116, 1 (1995).
12. A. Ludwig, Adv. Drug Deliv. Rev. 57, 1595 (2005).
13. J. R. Robinson, STP Pharm. Sci. 5, 839 (1989).
14. N. M. Davies, S. J. Farr, J. Hadgraft and I. W. Kellaway, Pharm. Res. 8, 1039 (1991).
15. P. Molyneux, Water-Soluble Synthetic Polymers: Properties and Behavior. CRC Press, Boca Raton, FL (1985).
16. M. N. V. Ravi Kumar, React. Funct. Polym. 46, 1 (2000).
17. S. A. Agnihotri, N. N. Mallikarjuna and T. M. Aminabhavi, J. Control. Rel. 100, 5 (2004).
18. M. V. Risbud, A. A. Hardikar, S. V. Bhat and R. R. Bhonde, J. Control Rel. 68, 23 (2000).
19. H. J. Kao, H. R. Lin, Y. L. Lo and S. P. Yu, J. Pharm. Pharmacol. 58, 179 (2006).
20. C. M. Lehr, J. A. Bouwstra, E. H. Schacht and H. E. Junginger, Int. J. Pharm. 78, 43 (1992).
21. S. Rossi, F. Ferrari, M. C. Bonferoni and C. Caramella, Eur. J. Pharm. Sci. 12, 479 (2001).
22. M. J. Alonso and A. Sanchez, J. Pharm. Pharmacol. 55, 1451 (2003).
23. P. Artursson, T. Lindmark, S. S. Davis and L. Illum, Pharm. Res. 11, 1358 (1994).
24. V. Dodane, M. A. Khan and J. R. Mervin, Int. J. Pharm. 182, 21 (1999).
25. H. R. Lin and K. C. Sung, J. Control. Rel. 69, 379 (2000).
26. H. R. Lin, K. C. Sung and W. J. Vong, Biomacromolecules 5, 2358 (2004).
27. G. A. F. Roberts and J. G. Domszy, Int. J. Biol. Macromol. 4, 374 (1982).
28. K. Tôei and T. Kohara, Anal. Chim. Acta 83, 59 (1976).
29. J. Ferguson, S. Al-Alawi and R. Granmayeh, Eur. Polym. J. 19, 475 (1983).
30. J. S. Ahn, H. K. Choi and C. S. Cho, Biomaterials 20, 923 (2001).
31. Y. Hu, X. Jiang, Y. Ding, H. Ge, Y. Yuan and C. Yang, Biomaterials 23, 3193 (2002).
32. S. Ding, Pharm. Sci. Technol. Today 1, 328 (1998).
33. P. Calvo, C. Remuñán-López, J. L. Vila-Jato and M. J. Alonso, J. Appl. Polym. Sci. 63, 125 (1997).
34. H. Q. Mao, K. Roy, V. L. Troung-Le, K. A. Janes, K. Y. Lin, Y. Wang, J. T. August and K. W. Leong, J. Control. Rel. 70, 399 (2001).
35. T. F. Patton and J. R. Robinson, J. Pharm. Sci. 65, 1295 (1976).
36. M. C. Makoid, J. W. Sieg and J. R. Robinson, J. Pharm. Sci. 65, 150 (1976).
37. T. F. Patton and J. R. Robinson, J. Pharm. Sci. 64, 267 (1975).
38. J. W. Sieg and J. R. Robinson, J. Pharm. Sci. 64, 931 (1975).
39. J. W. Sieg and J. R. Robinson, J. Pharm. Sci. 66, 1223 (1977).