Murine experimental autoimmune gastritis models refractive to development of intrinsic factor autoantibodies, cobalamin deficiency and pernicious anemia

Clinical Immunology

Volumn 122, Issue 1, 2007, Pages 41-52

  Greenwood, Deanne L V ^a   Sentry, John W ^a,b  

^a MONASH UNIVERSITY   (Australia)

^b ALFRED HOSPITAL   (Australia)

Author keywords

Autoantibodies; Autoimmunity; Cobalamin; Gastric intrinsic factor; Pernicious anemia

Indexed keywords

AUTOANTIBODY; AUTOANTIGEN; COBALAMIN; HYDROGEN POTASSIUM ADENOSINE TRIPHOSPHATASE; INTRINSIC FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY DETECTION; ANTIBODY PRODUCTION; ANTIBODY SPECIFICITY; ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNE GASTRITIS; CELL DESTRUCTION; CELL INFILTRATION; CONTROLLED STUDY; DISEASE COURSE; DISEASE MODEL; FEMALE; GASTRITIS; MALE; MOUSE; NONHUMAN; PERNICIOUS ANEMIA; PRIORITY JOURNAL; STOMACH PARIETAL CELL; SWINE; VITAMIN DEFICIENCY;

ANEMIA, PERNICIOUS; ANIMALS; AUTOANTIBODIES; AUTOANTIGENS; AUTOIMMUNE DISEASES; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GASTRITIS; H(+)-K(+)-EXCHANGING ATPASE; IMMUNOBLOTTING; INTRINSIC FACTOR; MALE; MICE; MICE, INBRED BALB C; MICE, TRANSGENIC; VITAMIN B 12; VITAMIN B 12 DEFICIENCY;

EID: 33845883001     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2006.08.013     Document Type: Article

References (50)

1. Oh R., and Brown D.L. Vitamin B12 deficiency. Am. Fam. Phys. 67 (2003) 979-986
2. Carmel R. Prevalence of undiagnosed pernicious anemia in the elderly. Arch. Intern. Med. 156 (1996) 1097-1100
3. Strickl R.G., and Mackay I.R. A reappraisal of the nature and significance of chronic atrophic gastritis. Am. J. Dig. Dis. 18 (1973) 426-440
4. Toh B.H., Biondo M., Marshall A., Greenwood D., Sentry J., and Alderuccio F. The gastric H/K ATPase in the pathogenesis of autoimmune gastritis. In: Sachs G. (Ed). Mechanisms and Consequences of Proton Transport (2002), Kluwer Academic 107-114
5. Taylor K.B., Roitt I.M., Doniach D., Couchman K.G., and Shapland C. Autoimmune phenomena in pernicious anaemia: gastric antibodies. Br. Med. J. 24 (1962) 1347-1352
6. Russell-Jones G.J., and Alpers D.H. Vitamin B12 transporters. Pharm. Biotechnol. 12 (1999) 493-520
7. Alderuccio F., Sentry J.W., Marshall A.C., Biondo M., and Toh B.H. Animal models of human disease: experimental autoimmune gastritis-a model for autoimmune gastritis and pernicious anemia. Clin. Immunol. 102 (2002) 48-58
8. Field J., Biondo M.A., Murphy K., Alderuccio F., and Toh B.H. Experimental autoimmune gastritis: mouse models of human organ-specific autoimmune disease. Int. Rev. Immunol. 24 (2005) 93-110
9. Toh B.H., Gleeson P.A., and van Driel I.R. Autoimmunity: a paradigm of autoimmune gastritis. Today's Life Sci. 5 (1993) 18-23
10. +-ATPase induces a reversible autoimmune gastritis. Immunol 92 (1997) 91-98
11. Greenwood D.L.V., Sentry J.W., and Toh B. Characterisation of Proton pump antibodies and stomach pathology in gastritis induced by neonatal immunisation without adjuvant. Autoimmunity 34 (2001) 81-94
12. Alderuccio F., Toh B.H., Tan S.S., Gleeson P.A., and van Driel I.R. An autoimmune disease with multiple molecular targets abrogated by the transgenic expression of a single autoantigen in the thymus. J. Exp. Med. 178 (1993) 419-426
13. Biondo M., Nasa Z., Marshall A., Toh B.-H., and Alderuccio F. Local transgenic expression of granulocyte macrophage-colony stimulating factor initiates autoimmunity. J. Immunol. 166 (2001) 2090-2099
14. Callaghan J.M., Toh B.H., Simpson R.J., Baldwin G.S., and Gleeson P.A. Rapid purification of the gastric H+/K+-ATPase complex by tomato-lectin affinity chromotography. Biochem. J. 283 (1992) 63-68
15. Laemmli U. Cleavage of structural proteins during the assembly of head bacteriophage T4. Nature 227 (1970) 680-685
16. Dury R.A.B., and Wallington E.A. Carlton's Histological Technique. 4th edn. (1967), Oxford University Press, New York
17. Beinborn M., Giebel J., Linck M., Cetin Y., Schwenk M., and Sewing K.F. Isolation, identification and quantitative evaluation of specific cell types from the mammalian gastric mucosa. Cell Tissue Res. 274 (1993) 229-240
18. ICSH. International Committee for Standardization in Haematology (ICSH) reference method for staining of blood and bone marrow films by azure B and eosin Y. Br. J. Haematol. 57 (1984) 707-710
19. Amann E., and Brosius J. ATG vectors' for regulated high-level expression of cloned genes in Escherichia coli. Gene 40 (1985) 183-190
20. Tung K.S.K., Smith S., Teuscher C., Cook C., and Anderson R.E. Murine autoimmune oophoritis, epididymoorchitis, and gastritis induced by day 3 thymectomy: immunopathology. Am. J. Pathol. 126 (1987) 293-302
21. Claeys D., Saraga E., Rossier B.C., and Kraehenbuhl J.-P. Neonatal injection of native proton pump antigens induces autoimmune gastritis in mice. Gastroenterology 113 (1997) 1136-1145
22. Greenwood D.L., and Sentry J.W. Gastritis in neonatal BALB/cCrSlc mice induced by immunization without adjuvant can be transferred to syngeneic nu/nu recipients. Scand. J. Immunol. 63 (2006) 50-58
23. Hennes A.R., Sevelius H., Lewellyn T., Joel W., Woods A.H., and Wolf S. Atrophic gastritis in dogs. Production by intradermal injection of gastric juice in Freund's adjuvant. Arch. Pathol. 73 (1962) 281-287
24. Ansar-Ahmed S., and Penhale W.J. Pathological changes in inbred strains of mice following early thymectomy and irradiation. Experientia 37 (1981) 32768
25. Kojima A., Taguchi O., and Nishizuka Y. Experimental production of possible autoimmune gastritis followed by macrocytic anemia in athymic nude mice. Lab. Invest. 42 (1980) 387-395
26. Fukuma K., Sakaguchi S., Kuribayashi K., Chen W.-L., Morishita R., Sekita K., Uchino H., and Masuda T. Immunologic and clinical studies in murine experimental autoimmune gastritis induced by neonatal thymectomy. Gastroenterology 94 (1988) 274-283
27. Whittingham S., and Mackay I.R. Pernicious anemia and gastric atrophy. In: Mackay I.R. (Ed). The Immune Diseases (1985), Academic Press, New York 243-266
28. Strickland R.G. Chronic gastritis and pernicious anaemia. In: CShanahan F. (Ed). Immunology and Immunopathology of the Liver and Gastrointestinal Tract (1990), Igaku-Shoin, New York, NY 535-546
29. Cummins D., and Ardeman S. Intrinsic factor antibodies and pernicious anaemia. Lancet 338 (1991) 383-384
30. Rose M.S., Doniach D., Chanarin I., Brostoff J., and Ardemann S. Intrinsic-factor antibodies in absence of pernicious anaemia: 3-7 year follow up. Lancet 2 (1970) 9-12
31. Hift W., Moshal M.G., and Pillay K. Megaloblastic anaemia, achlorhydria, low intrinsic factor, and intrinsic-factor antibodies in the absence of pernicious anaemia. Lancet 1 (1973) 570-573
32. Kojima A., and Prehn R.T. Genetic susceptibility to post-thymectomy autoimmune diseases in mice. Immunogenetics 14 (1981) 15-27
33. Baxter A.G., Jordan M.A., Silveira P.A., Wilson W.E., and Van Driel I.R. Genetic control of susceptibility to autoimmune gastritis. Int. Rev. Immunol. 24 (2005) 55-62
34. Uchida K., Okazaki K., Debrecceni A., Nishi T., Iwano H., Inai M., Uose S., Nakase H., Ohana M., Oshima C., Matsushima Y., Kawanami C., Hiai H., Masuda T., and Chiba T. Analysis of cytokines in the early development of gastric secondary lymphoid follicles in Helicobacter pylori-infected BALB/c mice with neonatal thymectomy. Infect. Immun. 69 (2001) 6749-6754
35. Ohata H., Kitauchi S., Yoshimura N., Mugitani K., Iwane M., Nakamura H., Yoshikawa A., Yanaoka K., Arii K., Tamai H., Shimizu Y., Takeshita T., Mohara O., and Ichinose M. Progression of chronic atrophic gastritis associated with Helicobacter pylori infection increases risk of gastric cancer. Int. J. Cancer 109 (2004) 138-143
36. Rose M., Chanarin I., Doniach D., Ardeman S., and Brostoff J. Intrinsic factor antibodies in the absence of pernicious anaemia. Clin. Sci. 38 (1970) 23
37. Howard T.A., Misra D.N., Grove M., Becichi M.J., Shao J.S., Gordon M., and Alpers D.H. Human gastric intrinsic factor expression is not restricted to parietal cells. J. Anat. 189 (1996) 303-313
38. Schepp W., Ruoff H.-J., and Miederer S.E. Cellular origin and release of intrinsic factor from isolated rat gastric mucosal cells. Biochem. Biophys. Acta 763 (1983) 426-433
39. Shao J., Sartor R.b., Dial E., Lichtenberger L.M., Schepp W., and Alpers D.H. Expression of intrinsic factor in rat and murine gastric mucosal cell lineages is modified by inflammation. Am. J. Pathol. 157 (2000) 117-1205
40. Judd L.M., Gleeson P.A., Toh B.H., and van Driel I.R. Autoimmune gastritis results in disruption of gastric epithelial cell development. Am. J. Physiol. 277 (1999) G209-G218
41. D'Elios M.M., Amedei A., Azzurri A., Benagiano M., Del Prete G., Bergman M.P., Vandenbroucke-Grauls C.M., and Appelmelk B.J. Molecular specificity and functional properties of autoreactive T-cell response in human gastric autoimmunity. Int. Rev. Immunol. 24 (2005) 111-122
42. De Silva H.D., Alderuccio F., Toh B.H., van Driel I.R., and Gleeso P.A. Defining T cell receptors which recognise the immunodominant epitope of the gastric autoantigen, the H/K ATPase beta-subunit. Autoimmunity 33 (2000) 1-14
43. Ma J.-Y., Borch K., Sjostrand S.E., Janson L., and Mardh S. Positive correlation between H,K-adenosine triphosphate autoantibodies and Helicobacter pylori antibodies in patients with pernicioua anemia. Scand. J. Gastroenterol. 29 (1994) 961-965
44. Claeys D., Faller G., Appelmelk B.J., Negrini R., and Kirchner T. The gastric H+,K+-ATPase is a major autoantigen in chronic Helicobacter pylori gastritis with body mucosa atrophy. Gastroenterology 115 (1998) 340-347
45. Presotto F., Sabini B., Cecchetto A., Plebani M., De Lazzari F., Pedini B., and Betterle C. Helicobacter pylori infection and gastric autoimmune diseases: is there a link?. Helicobacter 8 (2003) 578-584
46. Annibale B., Lahner E., Negrini R., Baccini F., Bordi C., Monarca B., and Fave G.D. Lack of specific association between gastric autoimmunity hallmarks and clinical presentations of atrophic body gastritis. World J. Gastroenterol. 11 (2005) 5351-5357
47. Kobayashi Y., Murakami H., Akbar S.M., Matsui H., and Onji M. A novel and effective approach of developing aggressive experimental autoimmune gastritis in neonatal thymectomized BALB/c mouse by polyinosinic:polycytidylic acid. Clin. Exp. Immunol. 136 (2004) 423-431
48. Suri-Payer E., Amar A.Z., Thornton A.M., and Shevach E.M. CD4+CD25+ T cells inhibit both the induction and effector function of autoreactive T cells and represent a unique lineage of immunoregulatory cells. J. Immunol. 160 (1998) 1212-1218
49. van Driel I.R., Baxter A.G., Laurie K.L., Zwar T.D., La Gruta N.L., Judd L.M., Scarff K.L., Silveira P.A., and Gleeson P.A. Immunopathogenesis, loss of T cell tolerance and genetics of autoimmune gastritis. Autoimmun. Rev. 1 (2002) 290-297
50. Alderuccio F., Gleeson P.A., Berzins S.P., Martin M., van Driel R., and Toh B.H. Expression of the gastric H/K ATPase a-subunit in the thymus may explain the dominant role of the b-subunit in the pathogenesis of autoimmune gastritis. Autoimmunity 25 (1997) 167-175