FV peptide induces apoptosis in HEp 2 and HeLa cells: An insight into the mechanism of induction

Journal of Carcinogenesis

Volumn 5, Issue , 2006, Pages

  Sri Balasubashini, M ^a   Karthigayan, S ^a   Somasundaram, S T ^a   Balasubramanian, T ^a   Rukkumani, R ^b   Menon, Venugopal P ^a  

^a ANNAMALAI UNIVERSITY   (India)

^b CENTRE FOR CELLULAR AND MOLECULAR BIOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CASPASE 8; DNA FRAGMENT; FISH VENOM; PEPTIDE; PROTEIN BCL 2;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; FISH; HELA CELL; HEP 2 CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; LYMPHOCYTE; MITOSIS INHIBITION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PURIFICATION; PTERIOS VOLITANS;

EID: 33845864722     PISSN: None     EISSN: 14773163     Source Type: Journal    
DOI: 10.1186/1477-3163-5-27     Document Type: Article

References (34)

1. Jemal A, Tiwari RC, Murray T, Ghafoor A, Samuels A, Ward E, Feuer FJ, Than MJ: Cancer statistics. CA Cancer J Clin 2004, 54:8-29.
2. Marks F, Muller-Decker K, Furstenberger G: A casual relationship between unscheduled eicosanoid signaling and tumor development:Cancer chemoprevention by inhibitors at arachidonic acid metabolisms. Toxicology 2000, 163:11-26.
3. Calmette A, Saenz A, Costi L: Effects du venin de cobra sur les greffes cancereuses et sur le cancer spontane (adeno-carcinoma) de la souris. C R Acad Sci 1933, 197:205-210.
4. Mayer AMS: Marine pharmacology in 1998: Antitumor and cytotoxic compounds. The Pharmacologist 1999, 41:159-164.
5. Baldi A, Morodoh J, Mendrano EE, Bonaparte YP, Lustig ES, Rumi L: Estudios tendientes a determinar las posibles propriedades antitumorales del veneno de cobra y del complejo crotoxina A y B. Medicina 1988, 48:337-344.
6. Braganaca BM: Biologically active components of cobra venom in relation to cancer research. Indian J Med Res 1976, 64:1197-207.
7. Abu-Sinna G, Esmat AY, Al-Zahaby AS, Soliman NA, Ibrahim TM: Fractionation of Cerastes cerastes cerastes snake venom and the antitumor action of its lethal and non-lethal fractions. Toxicon 2003, 42:207-215.
8. Orsolic N, Sver L, Vestovsek S, Terzic S: Basic, Inhibition of mammary carcinoma cell proliferation in vitro and tumor growth in vivo by bee venom. Toxicon 2003, 41:861-870.
9. Church JE, Hodgson WC: Advances and cholinergic activity contributes to the cardiovascular effects of lionfish (Pterios volitans) venom. Toxicon 2002, 40:787-796.
10. Halstead BW: Venomous fishes. In Poisonous and venomous marine animals of the world 2nd edition. NJ Darwin press, Princeton; 1965:1039.
11. Cohen AS, Olek AJ: An extract of lionfish (Pterios volitans) spine tissue contains acetyl choline, and a toxin that affects neuromuscular transmission. Toxicon 1989, 27:1367-1372.
12. Saunders PR, Taylor PB: Venom of the lionfish Pterios volitans. AM J Physiol 1959, 197:437-440.
13. Sri Balasubashini M, Karthigayan S, Somasundaram ST, Balasubramanian T, Menon VP: Apoptogenic effect of lionfish venom on Ehrlich's ascites carcinoma in mouse model. Int J Pharmacol 2006 in press.
14. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ: Protein Measurement with the folin phenol reagent. J Biol Chem 1951, 193:265-275.
15. Narayanan K, Balakrishnan A, Miyamoto S: NF-kappa B is essential for induction of pro-inflammatory cytokine genes by filarial parasitic sheath proteins. Mol Immunol 2000, 37:115-123.
16. Sambrook J, Rusell DW: Isolation of DNA from mammalian cells. In Molecular cloning. A Laboratory manual Cold Spring Harbour laboratory press, Cold Spring Harbour, New York; 2001:6.16 & 5.4.
17. Correa MC Jr, Durvanei AM, Silva MD, Pizzocaro KF, Ruiz IRG: Inhibition of melanoma cell tumerigenicity by the sanke venom toxin Jarrahagin. Toxicon 2002, 40:739-748.
18. Evan G, Littlewood T: A matter of life and cell death. Science 1998, 281:1317-1322.
19. White MA, Nicolette C, Minden A, Polverino A, Vanaeist L, Karrin M, Wigler MH: Ras functions can contribute to mammalian cell transformation. Cell 1995, 80:533-541.
20. Soengas MS, Alarcon RM, Yoshida H, Giaccia AJ, Hakem R, Malk TW, Lowe SW: Apaf-1 and caspase 9 in p53 - dependent apoptosis and tumor inhibition. Science 1999, 284:156-159.
21. Haldar S, Jena N, Crocje CM: Inactivation of Bcl-2 by phosphorylation. Proc Natl Acad Sci USA 1995, 92:4507-4511.
22. Schotte P, Geert VL, Isabble C, Peter V, Beyaert R: Lithium sensitizes tumor cells in an NF-kappa B-independent way to caspase activation and apoptosis induced by Tumor Necrosis Factor. J Biol Chem 2001, 276:25939-25945.
23. Shay JW, Bacchetti I: A survey of telomerase activity in human cancers. Eur J Cancer 1997, 33:787-791.
24. Lipps BY: Novel snake venom proteins cytolytic to cancer cells in vitro and In vivo systems. J Venom Anim Toxin 1999, 5(2):508-514.
25. Geerl R, Vaux DL: Apoptosis in the development of cancer. Carcinogenesis 2005, 26(2):263-270.
26. Thompson CB: Apoptosis in the pathogenesis and treatment of disease. Science 1995, 267:1456-1462.
27. Juin P, Huebor AO, Littlewood T, Evan G: C-myc induced apoptosis sensitization to apoptosis is mediated through cytochrome C release. Genes Dev 1999, 13:1367-1381.
28. Barnett M, Buckle V, Evans E, Porter A, Rout D, Smith A, Brown WR: Telomere directed fragmentation of mammalian chromosomes. Nucleic Acids Res 1993, 21:27-36.
29. Hengartner MO: The biochemistry of apoptosis. Nature 2000, 407:770-776.
30. Wyllie AH: Glucorcorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature 1980, 284:555-556.
31. Nagata S: Apoptotic DNA fragmentation. Exp Cell Res 2000, 256:12-18.
32. Araki S, Masuda S, Maeda H, Ying MJ, Hayashi H: Involvement of specific integrins in apoptosis induced by vascular apoptosis-inducing protein 1. Toxicon 2002, 40:535-542.
33. Waida JS, Dowdy SF: Modulation of cellular function by TAT mediated transduction of full length proteins. Curr Protein Pept Sci 2003, 4:97-104.
34. Snyder EL, Meade BR, Dowdy SF: Anticancer protein transduction strategies: reconstitution of p27 tumor suppressor function. Journal of Controlled Release 2003, 91(1):45-51.