Repeated maternal glucocorticoid treatment affects activity and hippocampal NMDA receptor expression in juvenile guinea pigs

Journal of Physiology

Volumn 578, Issue 1, 2007, Pages 249-257

  Owen, Dawn ^a   Matthews, Stephen G ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BETAMETHASONE; GLUCOCORTICOID; MESSENGER RNA; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY DISORDER; ARTICLE; BEHAVIOR DISORDER; BIRTH WEIGHT; CONTROLLED STUDY; FEMALE; FETOTOXICITY; FETUS; FETUS GROWTH; GENDER; GESTATIONAL AGE; GUINEA PIG; HIPPOCAMPUS; LOCOMOTION; MALE; NONHUMAN; OPEN FIELD BEHAVIOR; PREMATURE LABOR; PRENATAL EXPOSURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANXIETY; HIPPOCAMPAL CA1 REGION; HIPPOCAMPAL CA2 REGION; HIPPOCAMPAL CA3 REGION; JUVENILE ANIMAL; PROGENY; PROTEIN FUNCTION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BETAMETHASONE; BIRTH WEIGHT; BLOTTING, WESTERN; BRAIN; BRAIN CHEMISTRY; FEMALE; GLUCOCORTICOIDS; GUINEA PIGS; HIPPOCAMPUS; IN SITU HYBRIDIZATION; LITTER SIZE; MALE; MOTOR ACTIVITY; ORGAN SIZE; PREGNANCY; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 33845797457     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2006.122887     Document Type: Article

References (44)

1. Bradford MM (1976). A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye-binding. Anal Biochem 72, 248-254.
2. Brocklehurst P, Gates S, McKenzie-McHard K & Alfirevic & Chamberlain G (1999). Are we prescribing multiple courses of antenatal corticosteroids?A survey of practice in the UK. Br J Obstet Gynaecol 106, 977-979.
3. Choleris E, Thomas AW, Kavaliers M & Prato FS (2001). A detailed ethological analysis of the mouse open field test: Effects of diazepam, chlordiazepoxide and an extremely low frequency pulsed magnetic field. Neurosci Biobehav Rev 25, 235-260.
4. Crawley JN (1999). Behavioral phenotyping of transgenic and knockout mice: Experimental design and evaluation of general health, sensory functions, motor abilities, and specific behavioral tests. Brain Res 835, 18-26.
5. Cull-Candy S, Brickley S & Farrant M (2001). NMDA receptor subunits: diversity, development and disease. Curr Opin Neurobiol 11, 327-335.
6. Dobbing J & Sands J (1970). Growth and development of the brain and spinal cord of the guinea pig. Brain Res 17, 115-123.
7. Dobbing J & Sands J (1979). Comparative aspects of the brain growth spurt. Early Hum Dev 3, 79-83.
8. Feldmeyer D & Cull-Candy S (1996). Functional consequences of changes in NMDA receptor subunit expression during development. J Neurocytol 25, 857-867.
9. French NP, Hagan R, Evans SF, Mullan A & Newnham JP (2004). Repeated antenatal corticosteroids: Effects on cerebral palsy and childhood behavior. Am J Obstet Gynecol 190, 588-595.
10. Fujioka T, Fujioka A, Tan N, Chowdhury GM, Mouri H, Sakata Y & Nakamura S (2001). Mild prenatal stress enhances learning performance in the non-adopted rat offspring. Neuroscience 103, 301-307.
11. Gilstrap LC (2001). Antenatal corticosteroids revisited: Repeat courses -National Institutes of Health consensus development conference statement, August 17-18, 2000. Obstet Gynecol 98, 144-150.
12. Gutteling BM, de Weerth C, Willemsen-Swinkels SH, Huizink AC, Mulder EJ, Visser GH & Buitelaar JK (2005). The effects of prenatal stress on temperament and problem behavior of 27-month-old toddlers. Eur Child Adolesc Psychiatry 14, 41-51.
13. Jessa M, Nazar M, Bidzinski A & Plaznik A (1996). The effects of repeated administration of diazepam, MK-801 and CGP 37849 on rat behavior in two models of anxiety. Eur Neuropsychopharmacol 6, 55-61.
14. Jessa M, Nazar M & Plaznik A (1995). Anxiolytic-like action of intra-hippocampally administered NMDA antagonists in rats. Pol J Pharmacol 47, 81-84.
15. Kamphuis PJ, Gardoni F, Kamal A, Croiset G, Bakker JM, Cattabeni F, Gispen WH, van Bel F, Di Luca M & Wiegant VM (2003). Long-lasting effects of neonatal dexamethasone treatment on spatial learning and hippocampal synaptic plasticity: Involvement of the NMDA receptor complex. FASEB J 17, 911-913.
16. Kapoor A & Matthews SG (2005). Short periods of prenatal stress affect growth, behaviour and hypothalamo-pituitary-adrenal axis activity in male guinea pig offspring. J Physiol 566, 967-977.
17. Keightley M-C & Fuller PJ (1995). Cortisol resistance and the guinea pig glucocorticoid receptor. Steroids 60, 87-92.
18. Kew JN, Koester A, Moreau JL, Jenck F, Ouagazzal AM, Mutel V, Richards JG, Trube G, Fischer G, Montkowski A, Hundt W, Reinscheid RK, Pauly-Evers M, Kemp JA & Bluethmann H (2000). Functional consequences of reduction in NMDA receptor glycine affinity in mice carrying targeted point mutations in the glycine binding site. J Neurosci 20, 4037-4049.
19. Kreider ML, Levin ED, Seidler FJ & Slotkin TA (2005). Gestational dexamethasone treatment elicits sex-dependent alterations in locomotor activity, reward-based memory and hippocampal cholinergic function in adolescent and adult rats. Neuropsychopharmacology 30, 1617-1623.
20. Lehmann J, Stohr T & Feldon J (2000). Long-term effects of prenatal stress experiences and postnatal maternal separation on emotionality and attentional processes. Behav Brain Res 107, 133-144.
21. Lim G, Wang S, Zeng Q, Sung B, Yang L & Mao J (2005). Expression of spinal NMDA receptor and PKC gamma after chronic morphine is regulated by spinal glucocorticoid receptor. J Neurosci 25, 11145-11154.
22. Matthews SG (1998). Dynamic changes in glucocorticoid and mineralocorticoid receptor mRNA in the developing guinea pig brain. Dev Brain Res 107, 123-132.
23. Miyamoto Y, Yamada K, Nagai T, Mori H, Mishina M, Furukawa H, Noda Y & Nabeshima T (2004). Behavioural adaptations to addictive drugs in mice lacking the NMDA receptor epsilon1 subunit. Eur J Neurosci 19, 151-158.
24. Miyamoto Y, Yamada K, Noda Y, Mori H, Mishina M & Nabeshima T (2001). Hyperfunction of dopaminergic and serotonergic neuronal systems in mice lacking the NMDA receptor epsilon1 subunit. J Neurosci 21, 750-757.
25. Mohn AR, Gainetdinov RR, Caron MG & Koller BH (1999). Mice with reduced NMDA receptor expression display behaviors related to schizophrenia. Cell 98, 427-436.
26. Moriyoshi K, Masu M, Ishii T, Shigemoto R, Mizuno N & Nakanishi S (1991). Molecular cloning and characterization of the rat NMDA receptor. Nature 354, 31-37.
27. Northoff G, Richter A, Bermpohl F, Grimm S, Martin E, Marcar VL, Wahl C, Hell D & Boeker H (2005). NMDA hypofunction in the posterior cingulate as a model for schizophrenia: An exploratory ketamine administration study in fMRI. Schizophr Res 72, 235-248.
28. O'Connor TG, Heron J, Golding J, Beveridge M & Glover V (2002). Maternal antenatal anxiety and children's behavioural/emotional problems at 4 years. Report from the Avon Longitudinal Study of Parents and Children (see comments). Br J Psychiatry 180, 502-508.
29. O'Connor TG, Heron J, Golding J & Glover V (2003). Maternal antenatal anxiety and behavioural/emotional problems in children: A test of a programming hypothesis. J Child Psychol Psychiatry 44, 1025-1036.
30. Owen D, Andrews MH & Matthews SG (2005). Maternal adversity, glucocorticoids and programming of neuroendocrine function and behaviour. Neurosci Biobehav Rev 29, 209-226.
31. Owen D & Matthews SG (2003). Glucocorticoids and sex-dependent development of brain glucocorticoid and mineralocorticoid receptors. Endocrinology 144, 2775-2784.
32. Owen D, Setiawan E, Li A, McCabe L & Matthews SG (2004). Regulation of N-methyl-d-aspartate receptor subunit expression in the fetal guinea pig brain. Biol Reprod 71, 676-683.
33. Patin V, Lordi B, Vincent A & Caston J (2005). Effects of prenatal stress on anxiety and social interactions in adult rats. Brain Res Dev Brain Res 160, 265-274.
34. Plaznik A, Palejko W, Nazar M & Jessa M (1994). Effects of antagonists at the NMDA receptor complex in two models of anxiety. Eur Neuropsychopharmacol 4, 503-512.
35. Qin S, Zhao X, Pan Y, Liu J, Feng G, Fu J, Bao J, Zhang Z & He L (2005). An association study of the N-methyl-d-aspartate receptor NR1 subunit gene (GRIN1) and NR2B subunit gene (GRIN2B) in schizophrenia with universal DNA microarray. Eur J Hum Genet 13, 807-814.
36. Quinlivan JA, Evans SF, Dunlop SA, Beazley LD & Newnham JP (1998). Use of corticosteroids by Australian obstetricians -a survey of clinical practice. Aust NZ J Obstet Gynaecol 38, 1-7.
37. Rayburn WF, Christensen HD & Gonzalez CL (1997). A placebo-controlled comparison between betamethasone and dexamethasone for fetal maturation: Differences in neurobehavioral development of mice offspring. Am J Obstet Gynecol 176, 842-850.
38. Rodriguez A & Bohlin G (2005). Are maternal smoking and stress during pregnancy related to ADHD symptoms in children?J Child Psychol Psychiatry 46, 246-254.
39. Roussel S, Boissy A, Montigny D, Hemsworth PH & Duvaux-Ponter C (2005). Gender-specific effects of prenatal stress on emotional reactivity and stress physiology of goat kids. Horm Behav 47, 256-266.
40. Rowland LM, Astur RS, Jung RE, Bustillo JR, Lauriello J & Yeo RA (2005). Selective cognitive impairments associated with NMDA receptor blockade in humans. Neuropsychopharmacology 30, 633-639.
41. Van den Hove DL, Blanco CE, Aendekerk B, Desbonnet L, Bruschettini M, Steinbusch HP, Prickaerts J & Steinbusch HW (2005). Prenatal restraint stress and long-term affective consequences. Dev Neurosci 27, 313-320.
42. Wang S, Lim G, Zeng Q, Sung B, Yang L & Mao J (2005). Central glucocorticoid receptors modulate the expression and function of spinal NMDA receptors after peripheral nerve injury. J Neurosci 25, 488-495.
43. Welberg LA, Seckl JR & Holmes MC (2000). Inhibition of 11β-hydroxysteroid dehydrogenase, the foeto-placental barrier to maternal glucocorticoids, permanently programs amygdala GR mRNA expression and anxiety-like behaviour in the offspring. Eur J Neurosci 12, 1047-1054.
44. Welberg LA, Seckl JR & Holmes MC (2001). Prenatal glucocorticoid programming of brain corticosteroid receptors and corticotrophin-releasing hormone: Possible implications for behaviour. Neuroscience 104, 71-79.