Efficacy and limitations of natural killer cell depletion in cyclophosphamide-induced tolerance

Surgery Today

Volumn 37, Issue 1, 2007, Pages 24-29

  Shimizu, Ichiro ^a   Tomita, Yukihiro ^a   Okano, Shinji ^a   Iwai, Toshiro ^a   Kajiwara, Takashi ^a   Onzuka, Tatsushi ^a   Tominaga, Ryuji ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

Cyclophosphamide induced tolerance; Mixed chimerism; Natural killer cell

Indexed keywords

CYCLOPHOSPHAMIDE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY NK1.1; T LYMPHOCYTE RECEPTOR BETA CHAIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; CARDIAC GRAFT REJECTION; CHIMERA; CONTROLLED STUDY; DONOR; GRAFT REJECTION; GRAFT SURVIVAL; HEART GRAFT; IMMUNOLOGICAL TOLERANCE; MOUSE; NATURAL KILLER CELL; NONHUMAN; RECIPIENT; SKIN GRAFT; T LYMPHOCYTE;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, SURFACE; CHIMERISM; CYCLOPHOSPHAMIDE; HEART TRANSPLANTATION; IMMUNE TOLERANCE; IMMUNOSUPPRESSIVE AGENTS; KILLER CELLS, NATURAL; LECTINS, C-TYPE; MICE; MICE, INBRED STRAINS; MODELS, ANIMAL; SKIN TRANSPLANTATION; TRANSPLANTATION IMMUNOLOGY; TREATMENT OUTCOME;

EID: 33845735587     PISSN: 09411291     EISSN: 14362813     Source Type: Journal    
DOI: 10.1007/s00595-006-3329-z     Document Type: Article

References (29)

1. T Shin H Mayumi K Himeno H Sanui K Nomoto 1984 Druginduced tolerance to allografts in mice. I. Difference between tumor and skin grafts Transplantation 37 6 580 4
2. Y Tomita M Yoshikawa Q-W Zhang I Shimizu S Okano T Iwai 2000 Induction of permanent mixed chimerism and skin allograft tolerance across fully MHC-mismatched barriers by the additional myelosuppressive treatments in mice primed with allogeneic spleen cells followed by Cyclophosphamide J Immunol 164 34 41
3. T Maeda M Eto Y Nishimura K Nomoto YY Kong 1993 Direct evidence for clonal destruction of allo-reactive T cells in the mice treated with cyclophosphamide after allo-priming Immunology 78 1 113 21
4. Y Tomita Y Nishimura N Harada M Eto K Ayukawa Y Yoshikai 1990 Evidence for involvement of clonal anergy in MHC class I and class II disparate skin allograft tolerance after the termination of intrathymic clonal deletion J Immunol 145 12 4026 36
5. Y Tomita H Mayumi M Eto K Nomoto 1990 Importance of suppressor T cells in cyclophosphamide-induced tolerance to the non-H-2-encoded alloantigens. Is mixed chimerism really required in maintaining a skin allograft tolerance? J Immunol 144 2 463 73
6. M Eto H Mayumi Y Tomita Y Yoshikai K Nomoto 1990 Intrathymic clonal deletion of V beta 6+ T cells in cyclophosphamide-induced tolerance to H-2-compatible, Mls-disparate antigens J Exp Med 171 1 97 113
7. M Eto H Mayumi Y Tomita Y Yoshikai Y Nishimura K Nomoto 1990 The requirement of intrathymic mixed chimerism and clonal deletion for a long-lasting skin allograft tolerance in cyclophosphamide-induced tolerance Eur J Immunol 20 9 2005 13
8. M Eto H Mayumi Y Tomita Y Yoshikai Y Nishimura K Nomoto 1990 Sequential mechanisms of cyclophosphamide-induced skin allograft tolerance including the intrathymic clonal deletion followed by late breakdown of the clonal deletion J Immunol 145 5 1303 10
9. H Mayumi K Himeno K Tanaka N Tokuda JL Fan K Nomoto 1986 Drug-induced tolerance to allografts in mice. IX. Establishment of complete chimerism by allogeneic spleen cell transplantation from donors made tolerant to H-2-identical recipients Transplantation 42 4 417 22
10. H Mayumi K Himeno T Shin K Nomoto 1985 Drug-induced tolerance to allografts in mice. IV. Mechanisms and kinetics of cyclophosphamide-induced tolerance Transplantation 39 2 209 15
11. PS Russell CM Chase M Sykes H Ito J Shaffer RB Colvin 2001 Tolerance, mixed chimerism, and chronic transplant arteriopathy J Immunol 167 10 5731 40
12. WA Gourlay WH Chambers AP Monaco T Maki 1998 Importance of natural killer cells in the rejection of hamster skin xenografts Transplantation 65 5 727 34
13. A Raziuddin DL Longo M Bennett R Winkler-Pickett JR Ortaldo WJ Murphy 2002 Increased bone marrow allograft rejection by depletion of NK cells expressing inhibitory Ly49 NK receptors for donor class I antigens Blood 100 8 3026 33
14. J Liu MA Morris P Nguyen TC George E Koulich WC Lai 2000 Ly49I NK cell receptor transgene inhibition of rejection of H2b mouse bone marrow transplants J Immunol 164 4 1793 9
15. JN Beilke NR Kuhl L Van Kaer RG Gill 2005 NK cells promote islet allograft tolerance via a perforin-dependent mechanism Nat Med 11 10 1059 65
16. AG Murray RC Nelson GR Rayat JF Elliott GS Korbutt 1999 Neonatal porcine islet cells induce human CD4+, but not CD8+, lymphocyte proliferation and resist cell-mediated cytolytic injury in vitro Diabetes 48 9 1713 9
17. Y Tomita QW Zhang T Uchida M Yoshikawa I Shimizu T Iwai 2001 A technique of cervical aortic graft transplantation in mice J Heart Lung Transplant 20 6 699 702
18. M Bennett 1987 Biology and genetics of hybrid resistance Adv Immunol 41 333 445
19. M Orihuela DH Margulies WM Yokoyama 1996 The natural killer cell receptor Ly-49A recognizes a peptide-induced conformational determinant on its major histocompatibility complex class I ligand Proc Natl Acad Sci USA 93 21 11792 7
20. MY Olsson-Alheim M Salcedo HG Ljunggren K Karre CL Sentman 1997 NK cell receptor calibration: effects of MHC class I induction on killing by Ly49Ahigh and Ly49Alow NK cells J Immunol 159 7 3189 94
21. JO Manilay GL Waneck M Sykes 1999 Levels of Ly-49 receptor expression are determined by the frequency of interactions with MHC ligands: evidence against receptor calibration to a "useful" level J Immunol 163 5 2628 33
22. JO Manilay GL Waneck M Sykes 1998 Altered expression of Ly-49 receptors on NK cells developing in mixed allogeneic bone marrow chimeras Int Immunol 10 12 1943 55
23. LA Lee JJ Sergio M Sykes 1996 Natural killer cells weakly resist engraftment of allogeneic, long-term, multilineage-repopulating hematopoietic stem cells Transplantation 61 1 125 32
24. M Neipp JS Gammie BG Exner S Li WH Chambers SM Pham 1999 A partial conditioning approach to achieve mixed chimerism in the rat: depletion of host natural killer cells significantly reduces the amount of total body irradiation required for engraftment Transplantation 68 3 369 78
25. M Yoshikawa Y Tomita T Uchida QW Zhang K Nomoto 2000 Inability of cyclophosphamide-induced tolerance to permit engraftment of pluripotent stem cells contained in a moderate number of syngeneic bone marrow cells Immunobiology 201 5 552 67
26. K Ogasawara J Benjamin R Takaki JH Phillips LL Lanier 2005 Function of NKG2D in natural killer cell-mediated rejection of mouse bone marrow grafts Nat Immunol 6 9 938 45
27. A Raziuddin DL Longo L Mason JR Ortaldo M Bennett WJ Murphy 1998 Differential effects of the rejection of bone marrow allografts by the depletion of activating versus inhibiting Ly-49 natural killer cell subsets J Immunol 160 1 87 94
28. M Margalit Y Ilan M Ohana R Safadi R Alper Y Sherman 2005 Adoptive transfer of small numbers of DX5+ cells alleviates graft-versus-host disease in a murine model of semiallogeneic bone marrow transplantation: a potential role for NKT lymphocytes Bone Marrow Transplant 35 2 191 7
29. K Haraguchi T Takahashi A Matsumoto T Asai Y Kanda M Kurokawa 2005 Host-residual invariant NK T cells attenuate graft-versus-host immunity J Immunol 175 2 1320 8