Betaine attenuates alcoholic steatosis by restoring phosphatidylcholine generation via the phosphatidylethanolamine methyltransferase pathway

Journal of Hepatology

Volumn 46, Issue 2, 2007, Pages 314-321

  Kharbanda, Kusum K ^a,b   Mailliard, Mark E ^a,b   Baldwin, Cheryl R ^b   Beckenhauer, Harriet C ^a   Sorrell, Michael F ^a,b   Tuma, Dean J ^a,b  

^a VA Alcohol Research Center   (United States)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Alcohol; Apoptosis; Betaine; Liver; Methylation; Phosphatidylethanolamine methyltransferases; S adenosylhomocysteine; S adenosylmethionine

Indexed keywords

ALCOHOL; BETAINE; BETAINE HOMOCYSTEINE METHYLTRANSFERASE; HOMOCYSTEINE; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLETHANOLAMINE METHYLTRANSFERASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; FATTY LIVER; GENE EXPRESSION; LIVER CELL; MALE; METHYLATION; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BETAINE; DIET; ETHANOL; FATTY LIVER, ALCOHOLIC; LIPOTROPIC AGENTS; LIVER; MALE; PHOSPHATIDYLCHOLINES; PHOSPHATIDYLETHANOLAMINE N-METHYLTRANSFERASE; RATS; RATS, WISTAR; S-ADENOSYLHOMOCYSTEINE; S-ADENOSYLMETHIONINE; TRIGLYCERIDES;

EID: 33845676630     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2006.08.024     Document Type: Article

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