Postnatal switching of NMDA receptor subunits from NR2B to NR2A in rat facial motor neurons

European Journal of Neuroscience

Volumn 24, Issue 11, 2006, Pages 2987-2992

  Xing, Guo Gang ^a,b   Wang, Rengang ^a   Yang, Bo ^a   Zhang, Dongxian ^a  

^a BURNHAM INSTITUTE   (United States)

^b PEKING UNIVERSITY   (China)

Author keywords

Antagonist; Facial nucleus; Ifenprodil; NVP AAM007; Postnatal development; Wistar rats

Indexed keywords

IFENPRODIL; MESSENGER RNA; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; RECEPTOR SUBUNIT;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN ELECTROPHYSIOLOGY; CONTROLLED STUDY; ELECTRIC CURRENT; FACIAL NERVE NUCLEUS; GENE EXPRESSION; GROUPS BY AGE; IMMUNOHISTOCHEMISTRY; MOTONEURON; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; NUCLEOTIDE SEQUENCE; PATCH CLAMP; PERINATAL PERIOD; POLYMERASE CHAIN REACTION; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RECEPTOR BLOCKING; WISTAR RAT;

AGING; ANIMALS; ANIMALS, NEWBORN; CELL DIFFERENTIATION; CELLS, CULTURED; EXCITATORY AMINO ACID ANTAGONISTS; FACIAL NERVE; GLUTAMIC ACID; IMMUNOHISTOCHEMISTRY; MEMBRANE POTENTIALS; MOTOR NEURONS; PATCH-CLAMP TECHNIQUES; RATS; RATS, WISTAR; RECEPTORS, N-METHYL-D-ASPARTATE; RHOMBENCEPHALON; RNA, MESSENGER; SYNAPTIC TRANSMISSION; UP-REGULATION;

EID: 33845674690     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2006.05188.x     Document Type: Article

References (50)

1. 2+ block of NMDA receptor and restores NT-3-induced potentiation of AMPA-kainate responses in maturing rat motoneurons. J. Neurophysiol., 92, 2394-2404.
2. Arvanian, V.L. & Mendell, L.M. (2001) Removal of NMDA receptor Mg(2+) block extends the action of NT-3 on synaptic transmission in neonatal rat motoneurons. J. Neurophysiol., 86, 123-129.
3. Arvanov, V.L., Seebach, B.S. & Mendell, L.M. (2000) NT-3 evokes an LTP-like facilitation of AMPA/kainate receptor-mediated synaptic transmission in the neonatal rat spinal cord. J. Neurophysiol., 84, 752-758.
4. Barria, A. & Malinow, R. (2002) Subunit-specific NMDA receptor trafficking to synapses. Neuron, 35, 345-353.
5. Chatterton, J.E., Awobuluyi, M., Premkumar, L.S., Takahashi, H., Talantova, M., Shin, Y., Cui, J., Tu, S., Sevarino, K.A., Nakanishi, N., Tong, G., Lipton, S.A. & Zhang, D. (2002) Excitatory glycine receptors containing the NR3 family of NMDA receptor subunits. Nature, 415, 793-798.
6. Choi, D.W. (1988) Glutamate neurotoxicity and diseases of the nervous system. Neuron, 1, 623-634.
7. Ciabarra, A.M., Sullivan, J.M., Gahn, L.G., Pecht, G., Heinemann, S. & Sevarino, K.A. (1995) Cloning and characterization of χ-1: a developmentally regulated member of a novel class of the ionotropic glutamate receptor family. J. Neurosci., 15, 6498-6508.
8. Dingledine, R., Borges, K., Bowie, D. & Traynelis, S.F. (1999) The glutamate receptor ion channels. Pharmacol. Rev., 51, 7-61.
9. Fukaya, M., Hayashi, Y. & Watanabe, M. (2005) NR2 to NR3B subunit switchover of NMDA receptors in early postnatal motoneurons. Eur. J. Neurosci., 21, 1432-1436.
10. Harris, A.J. & McCaig, C.D. (1984) Motoneuron death and motor unit size during embryonic development of the rat. J. Neurosci., 4, 13-24.
11. Hori, Y. & Kanda, K. (1996) Developmental alterations in NMDA receptor-mediated currents in neonatal rat spinal motoneurons. Neurosci. Lett., 205, 99-102.
12. Inglis, F.M., Furia, F., Zuckerman, K.E., Strittmatter, S.M. & Kalb, R.G. (1998) The role of nitric oxide and NMDA receptors in the development of motor neuron dendrites. J. Neurosci., 18, 10493-10501.
13. Kalb, R.G. (1994) Regulation of motor neuron dendrite growth by NMDA receptor activation. Development, 120, 3063-3071.
14. Kim, M.J., Dunah, A.W., Wang, Y.T. & Sheng, M. (2005) Differential roles of NR2A- and NR2B-containing NMDA receptors in Ras-ERK signaling and AMPA receptor trafficking. Neuron, 46, 745-760.
15. Konnerth, A., Keller, B.U. & Lev-Tov, A. (1990) Patch clamp analysis of excitatory synapses in mammalian spinal cord slices. Pflugers Arch. - Eur. J. Physiol., 417, 285-290.
16. Krapivinsky, G., Krapivinsky, L., Manasian, Y., Ivanov, A., Tyzio, R., Pellegrino, C., Ben-Ari, Y., Clapham, D.E. & Medina, I. (2003) The NMDA receptor is coupled to the ERK pathway by a direct interaction between NR2B and RasGRF1. Neuron, 40, 775-784.
17. Kutsuwada, T., Kashiwabuchi, N., Mori, H., Sakimura, K., Kushiya, E., Araki, K., Meguro, H., Masaki, H., Kumanishi, T. & Arakawa, M. (1992) Molecular diversity of the NMDA receptor channel. Nature, 358, 36-41.
18. Lance-Jones, C. (1982) Motoneuron cell death in the developing lumbar spinal cord of the mouse. Brain Res., 256, 473-479.
19. Lau, L.F. & Huganir, R.L. (1995) Differential tyrosine phosphorylation of N-methyl-D-aspartate receptor subunits. J. Biol. Chem., 270, 20036-20041.
20. Laurie, D.J., Bartke, I., Schoepfer, R., Naujoks, K. & Seeburg, P.H. (1997) Regional, developmental and interspecies expression of the four NMDAR2 subunits, examined using monoclonal antibodies. Brain Res. Mol. Brain Res., 51, 23-32.
21. Lavezzari, G., McCallum, J., Dewey, C.M. & Roche, K.W. (2004) Subunit-specific regulation of NMDA receptor endocytosis. J. Neurosci., 24, 6383-6391.
22. Lipton, S.A. & Rosenberg, P.A. (1994) Mechanisms of disease: Excitatory amino acids as a final common pathway for neurologic disorders. N. Engl. J. Med., 330, 613-622.
23. Liu, X.B., Murray, K.D. & Jones, E.G. (2004) Switching of NMDA receptor 2A and 2B subunits at thalamic and cortical synapses during early postnatal development. J. Neurosci., 24, 8885-8895.
24. Llado, J., Caldero, J., Ribera, J., Tarabal, O., Oppenheim, R.W. & Esquerda, J.E. (1999) Opposing effects of excitatory amino acids on chick embryo spinal cord motoneurons: excitotoxic degeneration or prevention of programmed cell death. J. Neurosci., 19, 10803-10812.
25. Mayer, M.L. & Westbrook, G.L. (1987) The physiology of excitatory amino acids in the vertebrate central nervous system. Prog. Neurobiol., 28, 197-276.
26. Meguro, H., Mori, H., Araki, K., Kushiya, E., Kutsuwada, T., Yamazaki, M., Kumanishi, T., Arakawa, M., Sakimura, K. & Mishina, M. (1992) Functional characterization of a heteromeric NMDA receptor channel expressed from cloned cDNAs. Nature, 357, 70-74.
27. Monyer, H., Burnashev, N., Laurie, D.J., Sakmann, B. & Seeburg, P.H. (1994) Developmental and regional expression in the rat brain and functional properties of four NMDA receptors. Neuron, 12, 529-540.
28. Monyer, H., Sprengel, R., Schoepfer, R., Herb, A., Higuchi, M., Lomeli, H., Burnashev, N., Sakmann, B. & Seeburg, P.H. (1992) Heteromeric NMDA receptors: molecular and functional distinction of subtypes. Science, 256, 1217-1221.
29. Moriyoshi, K., Masu, M., Ishii, T., Shigemoto, R., Mizuno, N. & Nakanishi, S. (1991) Molecular cloning and characterization of the rat NMDA receptor. Nature, 354, 31-37.
30. Nakanishi, S., Nakajima, Y., Masu, M., Ueda, Y., Nakahara, K., Watanabe, D., Yamaguchi, S., Kawabata, S. & Okada, M. (1998) Glutamate receptors: brain function and signal transduction. Brain Res. Brain Res. Rev., 26, 230-235.
31. Nishi, M.H.H.L.H.P.K.M.H.Y. (2001) Motoneuron-specific expression of NR3B, a novel NMDA-type glutamate receptor subunit that works in a dominant-negative manner. J. Neurosci., 21, RC185.
32. Oppenheim, R.W. (1986) The absence of significant postnatal motoneuron death in the brachial and lumbar spinal cord of the rat. J. Comp. Neurol., 246, 281-286.
33. Oshima, S., Fukaya, M., Masabumi, N., Shirakawa, T., Oguchi, H. & Watanabe, M. (2002) Early onset of NMDA receptor GluR epsilon 1 (NR2A) expression and its abundant postsynaptic localization in developing motoneurons of the mouse hypoglossal nucleus. Neurosci. Res., 43, 239-250.
34. Paarmann, I., Frermann, D., Keller, B.U., Villmann, C., Breitinger, H.G. & Hollmann, M. (2005) Kinetics and subunit composition of NMDA receptors in respiratory-related neurons. J. Neurochem., 93, 812-824.
35. Palecek, J.I., Abdrachmanova, G., Vlachova, V. & Vyklick, L. Jr (1999) Properties of NMDA receptors in rat spinal cord motoneurons. Eur. J. Neurosci., 11, 827-836.
36. Premkumar, L.S., Qin, F. & Auerbach, A. (1997) Subconductance states of a mutant NMDA receptor channel kinetics, calcium, and voltage dependence. J. Gen. Physiol., 109, 181-189.
37. Seeburg, P.H., Higuchi, M. & Sprengel, R. (1998) RNA editing of brain glutamate receptor channels: mechanism and physiology. Brain Res. Brain Res. Rev., 26, 217-229.
38. Sheng, M., Cummings, J., Roldan, L.A., Jan, Y.N. & Jan, L.Y. (1994) Changing subunit composition of heteromeric NMDA receptors during development of rat cortex. Nature, 368, 144-147.
39. Stern, P., Behe, P., Schoepfer, R. & Colquhoun, D. (1992) Single-channel conductances of NMDA receptors expressed from cloned cDNAs: comparison with native receptors. Proc. R. Soc. Lond. Series B: Biol. Sci., 250, 271-277.
40. Sucher, N.J., Akabarian, S., Chi, C.L., Leclerc, C.L., Awobuluyi, M., Deitcher, D.L., Wu, M.K., Yuan, J.P., Jones, E.G. & Lipton, S.A. (1995) Developmental and regional expression pattern of a novel NMDA receptor-like subunit (NMDAR-L) in the rodent brain. J. Neurosci., 15, 6509-6520.
41. Sundstrom, E., Whittemore, S., Mo, L.L. & Seiger, A. (1997) Analysis of NMDA receptors in the human spinal cord. Exp. Neurol., 148, 407-413.
42. Tolle, T.R., Berthele, A., Zieglgansberger, W., Seeburg, P.H. & Wisden, W. (1993) The differential expression of 16 NMDA and non-NMDA receptor subunits in the rat spinal cord and in periaqueductal gray. J. Neurosci., 13, 5009-5028.
43. Wang, R. & Zhang, D. (2005) Memantine prolongs survival in an amyotrophic lateral sclerosis mouse model. Eur. J. Neurosci., 22, 2376-2380.
44. Watanabe, M., Inoue, Y., Sakimura, K. & Mishina, M. (1992) Developmental changes in distribution of NMDA receptor channel subunit mRNAs. Neuroreport, 3, 1138-1140.
45. Watanabe, M., Mishina, M. & Inoue, Y. (1994) Distinct spatiotemporal distributions of the N-methyl-D-aspartate receptor channel subunit mRNAs in the mouse cervical cord. J. Comp. Neurol., 345, 314-319.
46. Wenzel, A., Scheurer, L., Kunzi, R., Fritschy, J.M., Mohler, H. & Benke, D. (1995) Distribution of NMDA receptor subunit proteins NR2A, 2B, 2C and 2D in rat brain. Neuroreport, 7, 45-48.
47. Wyllie, D.J., Behe, P., Nassar, M., Schoepfer, R. & Colquhoun, D. (1996) Single-channel currents from recombinant NMDA NR1a/NR2D receptors expressed in Xenopus oocytes. Proc. R. Soc. Lond. Series B: Biol. Sci., 263, 1079-1086.
48. Yamakura, T. & Shimoji, K. (1999) Subunit- and site-specific pharmacology of the NMDA receptor channel. Prog. Neurobiol., 59, 279-298.
49. Zhou, M. & Baudry, M. (2006) Developmental changes in NMDA neurotoxicity reflect developmental changes in subunit composition of NMDA receptors. J. Neurosci., 26, 2956-2963.
50. Ziskind-Conhaim, L. (1990) NMDA receptors mediate poly- and monosynaptic potentials in motoneurons of rat embryos. J. Neurosci., 10, 125-135.