Testing for additivity at select mixture groups of interest based on statistical equivalence testing methods

Risk Analysis

Volumn 26, Issue 6, 2006, Pages 1601-1612

  Stork, LeAnna G ^a   Gennings, Chris ^b,c   Carchman, Richard A ^c   Carter Jr , Walter H ^b,c   Pounds, Joel ^d   Mumtaz, Moiz ^e  

^a MONSANTO COMPANY   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^c Solveritas   (United States)

^d PACIFIC NORTHWEST NATIONAL LABORATORY   (United States)

^e AGENCY FOR TOXIC SUBSTANCES AND DISEASE REGISTRY   (United States)

Author keywords

Antagonism; Low dose; Risk assessment; Synergy

Indexed keywords

PESTICIDES; RISK ASSESSMENT; STATISTICAL METHODS; TOXICITY; TUMORS;

ANTAGONISM; HEURISTIC ARGUMENTS; LOW-DOSE MIXTURE;

MIXTURES;

ORGANOPHOSPHATE PESTICIDE;

HYPOTHESIS TESTING; RISK ASSESSMENT; STATISTICAL APPLICATION; TOXICITY TEST;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; EXPOSURE; HYPOTHESIS; LOW DRUG DOSE; MALE; MOTOR ACTIVITY; NONHUMAN; RAT; RISK ASSESSMENT; STATISTICAL ANALYSIS;

ANIMALS; CHEMISTRY; COMPLEX MIXTURES; DATA INTERPRETATION, STATISTICAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; MALE; MODELS, STATISTICAL; ORGANOPHOSPHORUS COMPOUNDS; PESTICIDES; RATS; RESEARCH DESIGN; RISK; RISK ASSESSMENT;

EID: 33845663718     PISSN: 02724332     EISSN: 15396924     Source Type: Journal    
DOI: 10.1111/j.1539-6924.2006.00846.x     Document Type: Article

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