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Volumn 44, Issue 6, 2006, Pages 1607-1616

Intrahepatic virus-specific IL-10-producing CD8 T cells prevent liver damage during chronic hepatitis C virus infection

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; HLA A2 ANTIGEN; HLA B27 ANTIGEN; INTERLEUKIN 10; TETRAMER;

EID: 33845650186     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.21438     Document Type: Article
Times cited : (102)

References (43)
  • 2
    • 14944375587 scopus 로고    scopus 로고
    • Immunology of hepatitis B virus and hepatitis C virus infection
    • Rehermann B, Nascimbeni M. Immunology of hepatitis B virus and hepatitis C virus infection. Nat Rev Immunol 2005;5:215-229.
    • (2005) Nat Rev Immunol , vol.5 , pp. 215-229
    • Rehermann, B.1    Nascimbeni, M.2
  • 3
    • 23944467250 scopus 로고    scopus 로고
    • Adaptive immune responses in acute and chronic hepatitis C virus infection
    • Bowen DG, Walker CM. Adaptive immune responses in acute and chronic hepatitis C virus infection. Nature 2005;436:946-952.
    • (2005) Nature , vol.436 , pp. 946-952
    • Bowen, D.G.1    Walker, C.M.2
  • 4
    • 17644444485 scopus 로고    scopus 로고
    • Analysis of successful immune responses in persons infected with hepatitis C virus
    • Lechner F, Wong DK, Dunbar PR, Chapman R, Chung RT, Dohrenwend P, et al. Analysis of successful immune responses in persons infected with hepatitis C virus. J Exp Med 2000;191:1499-1512.
    • (2000) J Exp Med , vol.191 , pp. 1499-1512
    • Lechner, F.1    Wong, D.K.2    Dunbar, P.R.3    Chapman, R.4    Chung, R.T.5    Dohrenwend, P.6
  • 5
    • 0035000769 scopus 로고    scopus 로고
    • Sustained dysfunction of antiviral CD8+ T lymphocytes after infection with hepatitis C virus
    • Gruener NH, Lechner F, Jung MC, Diepolder H, Gerlach T, Lauer G, et al. Sustained dysfunction of antiviral CD8+ T lymphocytes after infection with hepatitis C virus. J Virol 2001;75:5550-5558.
    • (2001) J Virol , vol.75 , pp. 5550-5558
    • Gruener, N.H.1    Lechner, F.2    Jung, M.C.3    Diepolder, H.4    Gerlach, T.5    Lauer, G.6
  • 6
    • 0035914925 scopus 로고    scopus 로고
    • Determinants of viral clearance and persistence during acute hepatitis C virus infection
    • Thimme R, Oldach D, Chang KM, Steiger C, Ray SC, Chisari FV. Determinants of viral clearance and persistence during acute hepatitis C virus infection. J Exp Med 2001;194:1395-1406.
    • (2001) J Exp Med , vol.194 , pp. 1395-1406
    • Thimme, R.1    Oldach, D.2    Chang, K.M.3    Steiger, C.4    Ray, S.C.5    Chisari, F.V.6
  • 7
    • 0031057878 scopus 로고    scopus 로고
    • Cytotoxic T lymphocyte response and viral load in hepatitis C virus infection
    • Hiroishi K, Kita H, Kojima M, Okamoto H, Moriyama T, Kaneko T, et al. Cytotoxic T lymphocyte response and viral load in hepatitis C virus infection. HEPATOLOGY 1997;25:705-712.
    • (1997) Hepatology , vol.25 , pp. 705-712
    • Hiroishi, K.1    Kita, H.2    Kojima, M.3    Okamoto, H.4    Moriyama, T.5    Kaneko, T.6
  • 8
    • 0029778817 scopus 로고    scopus 로고
    • Quantitative analysis of the peripheral blood cytotoxic T lymphocyte response in patients with chronic hepatitis C virus infection
    • Rehermann B, Chang KM, McHutchison JG, Kokka R, Houghton M, Chisari FV. Quantitative analysis of the peripheral blood cytotoxic T lymphocyte response in patients with chronic hepatitis C virus infection. J Clin Invest 1996;98:1432-1440.
    • (1996) J Clin Invest , vol.98 , pp. 1432-1440
    • Rehermann, B.1    Chang, K.M.2    McHutchison, J.G.3    Kokka, R.4    Houghton, M.5    Chisari, F.V.6
  • 9
    • 0027443147 scopus 로고
    • Hepatitis C virus (HCV)-specific cytotoxic T lymphocytes recognize epitopes in the core and envelope proteins of HCV
    • Koziel MJ, Dudley D, Afdhal N, Choo QL, Houghton M, Ralston R, et al. Hepatitis C virus (HCV)-specific cytotoxic T lymphocytes recognize epitopes in the core and envelope proteins of HCV. J Virol 1993;67:7522-7532.
    • (1993) J Virol , vol.67 , pp. 7522-7532
    • Koziel, M.J.1    Dudley, D.2    Afdhal, N.3    Choo, Q.L.4    Houghton, M.5    Ralston, R.6
  • 10
    • 0031915132 scopus 로고    scopus 로고
    • Liver-derived CTL in hepatitis C virus infection: Breadth and specificity of responses in a cohort of persons with chronic infection
    • Wong DK, Dudley DD, Afdhal NH, Dienstag J, Rice CM, Wang L, et al. Liver-derived CTL in hepatitis C virus infection: breadth and specificity of responses in a cohort of persons with chronic infection. J Immunol 1998; 160:1479-1488.
    • (1998) J Immunol , vol.160 , pp. 1479-1488
    • Wong, D.K.1    Dudley, D.D.2    Afdhal, N.H.3    Dienstag, J.4    Rice, C.M.5    Wang, L.6
  • 12
    • 13044313467 scopus 로고    scopus 로고
    • Quantitative analysis of hepatitis C virus-specific CD8(+) T cells in peripheral blood and liver using peptide-MHC tetramers
    • He XS, Rehermann B, Lopez-Labrador FX, Boisvert J, Cheung R, Mumm J, et al. Quantitative analysis of hepatitis C virus-specific CD8(+) T cells in peripheral blood and liver using peptide-MHC tetramers. Proc Natl Acad Sci U S A 1999;96:5692-5697.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 5692-5697
    • He, X.S.1    Rehermann, B.2    Lopez-Labrador, F.X.3    Boisvert, J.4    Cheung, R.5    Mumm, J.6
  • 13
    • 0034858270 scopus 로고    scopus 로고
    • Direct ex vivo comparison of the breadth and specificity of the T cells in the liver and peripheral blood of patients with chronic HCV infection
    • Grabowska AM, Lechner F, Klenerman P, Tighe PJ, Ryder S, Ball JK, et al. Direct ex vivo comparison of the breadth and specificity of the T cells in the liver and peripheral blood of patients with chronic HCV infection. Eur J Immunol 2001;31:2388-2394.
    • (2001) Eur J Immunol , vol.31 , pp. 2388-2394
    • Grabowska, A.M.1    Lechner, F.2    Klenerman, P.3    Tighe, P.J.4    Ryder, S.5    Ball, J.K.6
  • 14
    • 2142702915 scopus 로고    scopus 로고
    • Hepatic expansion of a virus-specific regulatory CD8(+) T cell population in chronic hepatitis C virus infection
    • Accapezzato D, Francavilla V, Paroli M, Casciaro M, Chircu LV, Cividini A, et al. Hepatic expansion of a virus-specific regulatory CD8(+) T cell population in chronic hepatitis C virus infection. J Clin Invest 2004;113: 963-972.
    • (2004) J Clin Invest , vol.113 , pp. 963-972
    • Accapezzato, D.1    Francavilla, V.2    Paroli, M.3    Casciaro, M.4    Chircu, L.V.5    Cividini, A.6
  • 15
    • 0031068032 scopus 로고    scopus 로고
    • The role of hepatitis C virus-specific cytotoxic T lymphocytes in chronic hepatitis C
    • Nelson DR, Marousis CG, Davis GL, Rice CM, Wong J, Houghton M, et al. The role of hepatitis C virus-specific cytotoxic T lymphocytes in chronic hepatitis C. J Immunol 1997;158:1473-1481.
    • (1997) J Immunol , vol.158 , pp. 1473-1481
    • Nelson, D.R.1    Marousis, C.G.2    Davis, G.L.3    Rice, C.M.4    Wong, J.5    Houghton, M.6
  • 16
    • 0037337996 scopus 로고    scopus 로고
    • The presence of an intrahepatic cytotoxic T lymphocyte response is associated with low viral load in patients with chronic hepatitis C virus infection
    • Freeman AJ, Pan Y, Harvey CE, Post JJ, Law MG, White PA, et al. The presence of an intrahepatic cytotoxic T lymphocyte response is associated with low viral load in patients with chronic hepatitis C virus infection. J Hepatol 2003;38:349-356.
    • (2003) J Hepatol , vol.38 , pp. 349-356
    • Freeman, A.J.1    Pan, Y.2    Harvey, C.E.3    Post, J.J.4    Law, M.G.5    White, P.A.6
  • 17
    • 0034661993 scopus 로고    scopus 로고
    • Cutting edge: In situ tetramer staining of antigen-specific T cells in tissues
    • Skinner PJ, Daniels MA, Schmidt CS, Jameson SC, Haase AT. Cutting edge: In situ tetramer staining of antigen-specific T cells in tissues. J Immunol 2000;165:613-617.
    • (2000) J Immunol , vol.165 , pp. 613-617
    • Skinner, P.J.1    Daniels, M.A.2    Schmidt, C.S.3    Jameson, S.C.4    Haase, A.T.5
  • 19
    • 0036794559 scopus 로고    scopus 로고
    • Molecular anatomy of antigen-specific CD8(+) T cell engagement and synapse formation in vivo
    • McGavern DB, Christen U, Oldstone MB. Molecular anatomy of antigen-specific CD8(+) T cell engagement and synapse formation in vivo. Nat Immunol 2002;3:918-925.
    • (2002) Nat Immunol , vol.3 , pp. 918-925
    • McGavern, D.B.1    Christen, U.2    Oldstone, M.B.3
  • 20
    • 0029778988 scopus 로고    scopus 로고
    • An algorithm for the grading of activity in chronic hepatitis C
    • The METAVIR Cooperative Study Group
    • Bedossa P, Poynard T. An algorithm for the grading of activity in chronic hepatitis C. The METAVIR Cooperative Study Group. HEPATOLOGY 1996;24:289-293.
    • (1996) Hepatology , vol.24 , pp. 289-293
    • Bedossa, P.1    Poynard, T.2
  • 22
    • 0037105567 scopus 로고    scopus 로고
    • Impaired effector function of hepatitis C virus-specific CD8+ T cells in chronic hepatitis C virus infection
    • Wedemeyer H, He XS, Nascimbeni M, Davis AR, Greenberg HB, Hoofnagle JH, et al. Impaired effector function of hepatitis C virus-specific CD8+ T cells in chronic hepatitis C virus infection. J Immunol 2002;169: 3447-3458.
    • (2002) J Immunol , vol.169 , pp. 3447-3458
    • Wedemeyer, H.1    He, X.S.2    Nascimbeni, M.3    Davis, A.R.4    Greenberg, H.B.5    Hoofnagle, J.H.6
  • 23
    • 3042622803 scopus 로고    scopus 로고
    • Liver fibrosis and inflammation. A review
    • Kershenobich Stalnikowitz D, Weissbrod AB. Liver fibrosis and inflammation. A review. Ann Hepatol 2003;2:159-163.
    • (2003) Ann Hepatol , vol.2 , pp. 159-163
    • Weissbrod Ab, K.S.D.1
  • 25
    • 0036116355 scopus 로고    scopus 로고
    • Comprehensive analysis of CD8(+)-T-cell responses against hepatitis C virus reveals multiple unpredicted specificities
    • Lauer GM, Ouchi K, Chung RT, Nguyen TN, Day CL, Purkis DR, et al. Comprehensive analysis of CD8(+)-T-cell responses against hepatitis C virus reveals multiple unpredicted specificities. J Virol 2002;76:6104-6113.
    • (2002) J Virol , vol.76 , pp. 6104-6113
    • Lauer, G.M.1    Ouchi, K.2    Chung, R.T.3    Nguyen, T.N.4    Day, C.L.5    Purkis, D.R.6
  • 26
    • 0033849629 scopus 로고    scopus 로고
    • Liver-derived hepatitis C virus (HCV)-specific CD4(+) T cells recognize multiple HCV epitopes and produce interferon gamma
    • Schirren CA, Jung MC, Gerlach JT, Worzfeld T, Baretton G, Mamin M, et al. Liver-derived hepatitis C virus (HCV)-specific CD4(+) T cells recognize multiple HCV epitopes and produce interferon gamma. HEPATOLOGY 2000;32:597-603.
    • (2000) Hepatology , vol.32 , pp. 597-603
    • Schirren, C.A.1    Jung, M.C.2    Gerlach, J.T.3    Worzfeld, T.4    Baretton, G.5    Mamin, M.6
  • 27
    • 3042702285 scopus 로고    scopus 로고
    • Comparison of HCV-specific intrahepatic CD4+ T cells in HIV/HCV versus HCV
    • Graham CS, Curry M, He Q, Afdhal N, Nunes D, Fleming C, et al. Comparison of HCV-specific intrahepatic CD4+ T cells in HIV/HCV versus HCV. HEPATOLOGY 2004;40:125-132.
    • (2004) Hepatology , vol.40 , pp. 125-132
    • Graham, C.S.1    Curry, M.2    He, Q.3    Afdhal, N.4    Nunes, D.5    Fleming, C.6
  • 28
    • 0033485942 scopus 로고    scopus 로고
    • Chemokine and chemokine receptor interactions provide a mechanism for selective T cell recruitment to specific liver compartments within hepatitis C-infected liver
    • Shields PL, Morknd CM, Salmon M, Qin S, Hubscher SG, Adams DH. Chemokine and chemokine receptor interactions provide a mechanism for selective T cell recruitment to specific liver compartments within hepatitis C-infected liver. J Immunol 1999;163:6236-6243.
    • (1999) J Immunol , vol.163 , pp. 6236-6243
    • Shields, P.L.1    Morknd, C.M.2    Salmon, M.3    Qin, S.4    Hubscher, S.G.5    Adams, D.H.6
  • 29
    • 0029810790 scopus 로고    scopus 로고
    • Progressive liver injury in chronic hepatitis C infection correlates with increased intrahepatic expression of Th1-associated cytokines
    • Napoli J, Bishop GA, McGuinness PH, Painter DM, McCaughan GW. Progressive liver injury in chronic hepatitis C infection correlates with increased intrahepatic expression of Th1-associated cytokines. HEPATOLOGY 1996;24:759-765.
    • (1996) Hepatology , vol.24 , pp. 759-765
    • Napoli, J.1    Bishop, G.A.2    McGuinness, P.H.3    Painter, D.M.4    McCaughan, G.W.5
  • 30
    • 0030704726 scopus 로고    scopus 로고
    • A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis
    • Groux H, O'Garra A, Bigler M, Rouleau M, Amonenko S, de Vries JE, et al. A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis. Nature 1997;389:737-742.
    • (1997) Nature , vol.389 , pp. 737-742
    • Groux, H.1    O'Garra, A.2    Bigler, M.3    Rouleau, M.4    Amonenko, S.5    De Vries, J.E.6
  • 34
    • 0037220482 scopus 로고    scopus 로고
    • Liver fibrosis - From bench to bedside
    • Friedman SL. Liver fibrosis - from bench to bedside. J Hepatol 2003; 38(Suppl 1):S38-S53.
    • (2003) J Hepatol , vol.38 , Issue.SUPPL. 1
    • Friedman, S.L.1
  • 35
    • 0031972755 scopus 로고    scopus 로고
    • Expression of interleukin-10 by in vitro and in vivo activated hepatic stellate cells
    • Wang SC, Ohata M, Schrum L, Rippe RA, Tsukamoto H. Expression of interleukin-10 by in vitro and in vivo activated hepatic stellate cells. J Biol Chem 1998;273:302-308.
    • (1998) J Biol Chem , vol.273 , pp. 302-308
    • Wang, S.C.1    Ohata, M.2    Schrum, L.3    Rippe, R.A.4    Tsukamoto, H.5
  • 36
    • 0031051850 scopus 로고    scopus 로고
    • Hepatoprotective role of interleukin 10 in galactosamine/ lipopolysaccharide mouse liver injury
    • Louis H, Le Moine O, Peny MO, Gulbis B, Nisol F, Goldman M, et al. Hepatoprotective role of interleukin 10 in galactosamine/lipopolysaccharide mouse liver injury. Gastroenterology 1997;112:935-942.
    • (1997) Gastroenterology , vol.112 , pp. 935-942
    • Louis, H.1    Le Moine, O.2    Peny, M.O.3    Gulbis, B.4    Nisol, F.5    Goldman, M.6
  • 37
    • 17344371807 scopus 로고    scopus 로고
    • Interleukin-10 controls neutrophilic infiltration, hepatocyte proliferation, and liver fibrosis induced by carbon tetrachloride in mice
    • Louis H, Van Laethem JL, Wu W, Quertinmont E, Degraef C, Van den Berg K, et al. Interleukin-10 controls neutrophilic infiltration, hepatocyte proliferation, and liver fibrosis induced by carbon tetrachloride in mice. HEPATOLOGY 1998;28:1607-1615.
    • (1998) Hepatology , vol.28 , pp. 1607-1615
    • Louis, H.1    Van Laethem, J.L.2    Wu, W.3    Quertinmont, E.4    Degraef, C.5    Van Den Berg, K.6
  • 38
    • 4444289142 scopus 로고    scopus 로고
    • Immune stimulation of hepatic fibrogenesis by CD8 cells and attenuation by transgenic interleukin-10 from hepatocytes
    • Safadi R, Ohta M, Alvarez CE, Fiel MI, Bansal M, Mehal WZ, et al. Immune stimulation of hepatic fibrogenesis by CD8 cells and attenuation by transgenic interleukin-10 from hepatocytes. Gastroenterology 2004; 127:870-882.
    • (2004) Gastroenterology , vol.127 , pp. 870-882
    • Safadi, R.1    Ohta, M.2    Alvarez, C.E.3    Fiel, M.I.4    Bansal, M.5    Mehal, W.Z.6
  • 39
    • 21344442507 scopus 로고    scopus 로고
    • Cellular immune selection with hepatitis C virus persistence in humans
    • Cox AL, Mosbruger T, Mao Q, Liu Z, Wang XH, Yang HC, et al. Cellular immune selection with hepatitis C virus persistence in humans. J Exp Med 2005;201:1741-1752.
    • (2005) J Exp Med , vol.201 , pp. 1741-1752
    • Cox, A.L.1    Mosbruger, T.2    Mao, Q.3    Liu, Z.4    Wang, X.H.5    Yang, H.C.6
  • 40
    • 18244397979 scopus 로고    scopus 로고
    • The outcome of hepatitis C virus infection is predicted by escape mutations in epitopes targeted by cytotoxic T lymphocytes
    • Erickson AL, Kimura Y, Igarashi S, Eichelberger J, Houghton M, Sidney J, et al. The outcome of hepatitis C virus infection is predicted by escape mutations in epitopes targeted by cytotoxic T lymphocytes. Immunity 2001;15:883-895.
    • (2001) Immunity , vol.15 , pp. 883-895
    • Erickson, A.L.1    Kimura, Y.2    Igarashi, S.3    Eichelberger, J.4    Houghton, M.5    Sidney, J.6
  • 41
    • 0030671121 scopus 로고    scopus 로고
    • Immunological significance of cytotoxic T lymphocyte epitope variants in patients chronically infected by the hepatitis C virus
    • Chang KM, Rehermann B, McHutchison JG, Pasquinelli C, Southwood S, Sette A, et al. Immunological significance of cytotoxic T lymphocyte epitope variants in patients chronically infected by the hepatitis C virus. J Clin Invest 1997;100:2376-2385.
    • (1997) J Clin Invest , vol.100 , pp. 2376-2385
    • Chang, K.M.1    Rehermann, B.2    McHutchison, J.G.3    Pasquinelli, C.4    Southwood, S.5    Sette, A.6
  • 42
    • 18744382757 scopus 로고    scopus 로고
    • Strain-specific T-cell suppression and protective immunity in patients with chronic hepatitis C virus infection
    • Sugimoto K, Kaplan DE, Ikeda F, Ding J, Schwartz J, Nunes FA, et al. Strain-specific T-cell suppression and protective immunity in patients with chronic hepatitis C virus infection. J Virol 2005;79:6976-6983.
    • (2005) J Virol , vol.79 , pp. 6976-6983
    • Sugimoto, K.1    Kaplan, D.E.2    Ikeda, F.3    Ding, J.4    Schwartz, J.5    Nunes, F.A.6
  • 43
    • 0032475822 scopus 로고    scopus 로고
    • Hepatitis C viral dynamics in vivo and the antiviral efficacy of interferon-alpha therapy
    • Neumann AU, Lam NP, Dahari H, Gretch DR, Wiley TE, Layden TJ, et al. Hepatitis C viral dynamics in vivo and the antiviral efficacy of interferon-alpha therapy. Science 1998;282:103-107.
    • (1998) Science , vol.282 , pp. 103-107
    • Neumann, A.U.1    Lam, N.P.2    Dahari, H.3    Gretch, D.R.4    Wiley, T.E.5    Layden, T.J.6


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