N6-Cycloalkyl-2-substituted adenosine derivatives as selective, high affinity adenosine A1 receptor agonists

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 1, 2007, Pages 161-166

  Elzein, Elfatih ^a   Kalla, Rao ^a   Li, Xiaofen ^a   Perry, Thao ^a   Marquart, Tim ^a   Micklatcher, Mark ^a   Li, Yuan ^a   Wu, Yuzhi ^a   Zeng, Dewan ^a   Zablocki, Jeff ^a  

^a CV THERAPEUTICS INC   (United States)

Author keywords

A1 Adenosine receptors

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); ADENOSINE A1 RECEPTOR AGONIST; ADENOSINE A3 RECEPTOR AGONIST; ADENOSINE DERIVATIVE; AMIDE; CARBOXYLIC ACID DERIVATIVE; PYRAZOLE DERIVATIVE; REGADENOSON; ADENOSINE; ADENOSINE A1 RECEPTOR; ANTIARRHYTHMIC AGENT; ANTILIPEMIC AGENT; DRUG DERIVATIVE; N CYCLOPENTYL 2 (4 CARBAMOYLPYRAZOL 1 YL)ADENOSINE; N NORBORNYL 2 (4 CARBOXYPYRAZOL 1 YL)ADENOSINE; N-CYCLOPENTYL-2-(4-CARBAMOYLPYRAZOL-1-YL)ADENOSINE; N-NORBORNYL-2-(4-CARBOXYPYRAZOL-1-YL)ADENOSINE;

ALKYLATION; ARTICLE; BINDING AFFINITY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG SYNTHESIS; NONHUMAN; RECEPTOR AFFINITY; SUBSTITUTION REACTION; CHEMICAL STRUCTURE; CHEMISTRY; DRUG POTENTIATION; HUMAN;

ADENOSINE; ANTI-ARRHYTHMIA AGENTS; ANTILIPEMIC AGENTS; HUMANS; MOLECULAR STRUCTURE; PYRAZOLES; RECEPTOR, ADENOSINE A1;

EID: 33845625536     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.09.065     Document Type: Article

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