Recognizing genes differentially regulated in vitro by the multiple endocrine neoplasia type 1 (MEN1) gene, using RNA interference and oligonucleotide microarrays

Surgery

Volumn 140, Issue 6, 2006, Pages 921-931

  Stålberg, Peter ^a   Santesson, Mårten ^a   Ekeblad, Sara ^a   Lejonklou, Margareta Halin ^a   Skogseid, Britt ^a  

^a UPPSALA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CELL FATE; CONTROLLED STUDY; DNA MICROARRAY; DOWN REGULATION; ENDOCRINE CELL; GENE CONTROL; GENE EXPRESSION REGULATION; GENE IDENTIFICATION; GENE SILENCING; HUMAN; HUMAN CELL; IN VITRO STUDY; MAJOR CLINICAL STUDY; MULTIPLE ENDOCRINE NEOPLASIA; PANCREAS ISLET CELL TUMOR; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; UPREGULATION;

CELL LINE, TUMOR; DNA, NEOPLASM; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, NEOPLASM; HUMANS; NF-KAPPA B; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PANCREATIC NEOPLASMS; PROTO-ONCOGENE PROTEINS; RECEPTORS, NOTCH; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA, MESSENGER; RNA, NEOPLASM; TRANSFECTION; WNT PROTEINS;

EID: 33845593204     PISSN: 00396060     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.surg.2006.06.038     Document Type: Article

References (25)

1. Wermer P. Genetic aspects of adenomatosis of endocrine glands. Am J Med 16 (1954) 363-371
2. Chandrasekharappa S.C., Guru S.C., Manickam P., Olufemi S.E., Collins F.S., Emmert-Buck M.R., et al. Positional cloning of the gene for multiple endocrine neoplasia-type 1. Science 276 (1997) 404-407
3. Agarwal S.K., Kennedy P.A., Scacheri P.C., Novotny E.A., Hickman A.B., Cerrato A., et al. Menin molecular interactions: insights into normal functions and tumorigenesis. Horm Metab Res 37 (2005) 369-374
4. Agarwal S.K., Kester M.B., Debelenko L.V., Heppner C., Emmert-Buck M.R., Skarulis M.C., et al. Germline mutations of the MEN1 gene in familial multiple endocrine neoplasia type 1 and related states. Hum Mol Genet 6 (1997) 1169-1175
5. Tanaka C., Kimura T., Yang P., Moritani M., Yamaoka T., Yamada S., et al. Analysis of loss of heterozygosity on chromosome 11 and infrequent inactivation of the MEN1 gene in sporadic pituitary adenomas [comments]. J Clin Endocrinol Metab 83 (1998) 2631-2634
6. Heppner C., Kester M.B., Agarwal S.K., Debelenko L.V., Emmert-Buck M.R., Guru S.C., et al. Somatic mutation of the MEN1 gene in parathyroid tumours. Nat Genet 16 (1997) 375-378
7. Hessman O., Lindberg D., Skogseid B., Carling T., Hellman P., Rastad J., et al. Mutation of the multiple endocrine neoplasia type 1 gene in nonfamilial, malignant tumors of the endocrine pancreas. Cancer Res 58 (1998) 377-379
8. Wang E.H., Ebrahimi S.A., Wu A.Y., Kashefi C., Passaro Jr. E., and Sawicki M.P. Mutation of the MENIN gene in sporadic pancreatic endocrine tumors. Cancer Res 58 (1998) 4417-4420
9. Stalberg P., Grimfjard P., Santesson M., Zhou Y., Lindberg D., Gobl A., et al. Transfection of the multiple endocrine neoplasia type 1 gene to a human endocrine pancreatic tumor cell line inhibits cell growth and affects expression of JunD, delta-like protein 1/preadipocyte factor-1, proliferating cell nuclear antigen, and QM/Jif-1. J Clin Endocrinol Metab 89 (2004) 2326-2337
10. Zamore P.D., Tuschl T., Sharp P.A., and Bartel D.P. RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals. Cell 101 (2000) 25-33
11. Elbashir S.M., Lendeckel W., and Tuschl T. RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev 15 (2001) 188-200
12. Parekh D., Ishizuka J., Townsend Jr. C.M., Haber B., Beauchamp R.D., Karp G., et al. Characterization of a human pancreatic carcinoid in vitro: morphology, amine and peptide storage, and secretion. Pancreas 9 (1994) 83-90
13. Elbashir S.M., Harborth J., Lendeckel W., Yalcin A., Weber K., and Tuschl T. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411 (2001) 494-498
14. Brummelkamp T.R., Bernards R., and Agami R. A system for stable expression of short interfering RNAs in mammalian cells. Science 296 (2002) 550-553
15. Heid C.A., Stevens J., Livak K.J., and Williams P.M. Real-time quantitative PCR. Genome Res 6 (1996) 986-994
16. Zhou Y., Gobl A., Wang S., Jacobsen M.B., Janson E.T., Haines III G.K., et al. Expression of p68 protein kinase and its prognostic significance during IFN-alpha therapy in patients with carcinoid tumours. Eur J Cancer 34 (1998) 2046-2052
17. Scacheri P.C., Rozenblatt-Rosen O., Caplen N.J., Wolfsberg T.G., Umayam L., Lee J.C., et al. Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells. Proc Natl Acad Sci U S A 101 (2004) 1892-1897
18. Sledz C.A., Holko M., de Veer M.J., Silverman R.H., and Williams B.R. Activation of the interferon system by short-interfering RNAs. Nat Cell Biol 5 (2003) 834-839
19. Lopez-Egido J.R., Claessen S.M.H., Macville M., Albrechts J.C.M., Skogseid B., and Speel E.J.M. Spectral karyotypic, comparative genomic and FISH analysis of the human serotonin-producing endocrine pancreatic tumor cell line BON-1. J Intern Med 255 (2004) 724 abstracts for MEN 2004
20. Vortmeyer A.O., Huang S., Lubensky I., and Zhuang Z. Non-islet origin of pancreatic islet cell tumors. J Clin Endocrinol Metab 89 (2004) 1934-1938
21. Fontaniere S., Casse H., Bertolino P., and Zhang C.X. Analysis of p27(Kip1) expression in insulinomas developed in pancreatic beta-cell specific Men1 mutant mice. Fam Cancer 5 (2006) 49-54
22. Marshall E. Getting the noise out of gene arrays. Science 306 (2004) 630-631
23. de Kok J.B., Roelofs R.W., Giesendorf B.A., Pennings J.L., Waas E.T., Feuth T., et al. Normalization of gene expression measurements in tumor tissues: comparison of 13 endogenous control genes. Lab Invest 85 (2005) 154-159
24. Kunnimalaiyaan M., Yan S., Wong F., Zhang Y.W., and Chen H. Hairy enhancer of split-1 (HES-1), a Notch1 effector, inhibits the growth of carcinoid tumor cells. Surgery 138 (2005) 1137-1142 discussion 1142
25. Hessman O., Lindberg D., Einarsson A., Lillhager P., Carling T., Grimelius L., et al. Genetic alterations on 3p, 11q13, and 18q in nonfamilial and MEN 1-associated pancreatic endocrine tumors. Genes Chromosomes Cancer 26 (1999) 258-264