Relaxation of human placental arteries and veins by ATP-sensitive potassium channel openers

European Journal of Clinical Investigation

Volumn 37, Issue 1, 2007, Pages 65-72

  Jewsbury, S ^a   Baker, P N ^a   Wareing, M ^a,b  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b ST MARY S HOSPITAL   (United Kingdom)

Author keywords

Arteries; Placenta; Potassium channels; Veins

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; 5 AMINO N [2 (2 CHLOROPHENYL)ETHYL] N' CYANO 3 PYRIDINECARBOXAMIDINE; 6 ANILINO 5,8 QUINOLINEQUINONE; ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; CROMAKALIM; N CYANO N' (2 NITROXYETHYL) 3 PYRIDINECARBOXIMIDAMIDE; NITRIC OXIDE; PINACIDIL; POTASSIUM CHANNEL AFFECTING AGENT; POTASSIUM CHANNEL STIMULATING AGENT; PRETONE;

ARTICLE; BLOOD VESSEL TONE; CONTROLLED STUDY; FEMALE; FETOPLACENTAL UNIT; HUMAN; HUMAN TISSUE; MYOGRAPHY; PLACENTA; PRIORITY JOURNAL; PROTEIN EXPRESSION; VASCULARIZATION; VASODILATATION;

ADENOSINE TRIPHOSPHATE; ANIMALS; ARTERIES; FEMALE; HUMANS; MUSCLE RELAXATION; PLACENTA; POTASSIUM CHANNELS; PREGNANCY; PREGNANCY, ANIMAL; PYRIDINES; RATS; VASODILATION; VEINS;

EID: 33845572255     PISSN: 00142972     EISSN: 13652362     Source Type: Journal    
DOI: 10.1111/j.1365-2362.2007.01749.x     Document Type: Article

References (31)

1. Edwards G, Weston AH. The pharmacology of ATP-sensitive potassium channels. Annu Rev Pharmacol Toxicol 1993;33:597-637.
2. Wanstall JC. The pulmonary vasodilator properties of potassium channel opening drugs. Gen Pharmacol 1996;27:599-605.
3. Seino S. ATP-sensitive potassium channels: a model of heteromultimeric potassium channel/receptor assemblies. Annu Rev Physiol 1999;61:337-62.
4. + channel openers. Pharmacol Ther 2000;85:39-53.
5. Brayden JE. Functional roles of KATP channels in vascular smooth muscle. Clin Exp Pharmacol Physiol 2002;29:312-6.
6. + channel openers. Trends Pharmacol Sci 1990;11:417-22.
7. Kingdom JC, Burrell SJ, Kaufmann P. Pathology and clinical implications of abnormal umbilical artery Doppler waveforms. Ultrasound Obstet Gynecol 1997;9:271-86.
8. Challis DE, Pfarrer CD, Ritchie JW, Koren G, Adamson SL. Glucose metabolism is elevated and vascular resistance and maternofetal transfer is normal in perfused placental cotyledons from severely growth-restricted fetuses. Pediatr Res 2000;47:309-15.
9. Guiet-Bara A, Ibrahim B, Leveteau J, Bara M. Calcium channels, potassium channels and membrane potential of smooth muscle cells of human allantochorial placental vessels. Bioelectrochem Bioenerg 1999;48:407-13.
10. Guiet-Bara A, Bara M. Evidence of K and Ca channels in endothelial cells of human allantochorial placental vessels. Cell Mol Biol (Noisy-le-Grand) 2002; 48 Online Publications: OL317-322.
11. Hampl V, Bibova J, Stranak Z, Wu X, Michelakis ED, Hashimoto K et al. Hypoxic fetoplacental vasoconstriction in humans is mediated by potassium channel inhibition. Am J Physiol Heart Circ Physiol 2002;283:H2440-9.
12. Wareing M, Bai X, Seghier F, Turner CM, Greenwood SL, Baker PN et al. Expression and function of potassium channels in the human placental vasculature. Am J Physiol Regul Integr Comp Physiol 2006;291:R437-46.
13. Wareing M, Greenwood SL, Fyfe GK, Baker PN, Taggart MJ. Glibenclamide Inhibits Agonist-induced Vasoconstriction of Placental Chorionic Plate Arteries. Placenta 2006;27:660-8.
14. Babenko AP, Aguilar-Bryan L, Bryan J. A view of sur/KIR6.X, KATP channels. Annu Rev Physiol 1998;60:667-87.
15. Wanstall JC, Gambino A, Thomas BJ. KRN2391: dual action on rat pulmonary artery and no loss of potency in pulmonary hypertension. Clin Exp Pharmacol Physiol 2000;27:288-94.
16. Petersson J, Ryman T, Hogestatt ED. Vasodilator effects of KRN2391, levcromakalim and 3-morpholino-sydnonimin in human pial and omental arteries. Naunyn Schmiedebergs Arch Pharmacol 2000;362:68-73.
17. Kashiwabara T, Nakajima S, Izawa T, Fukushima H, Nishikori K. Characteristics of KRN2391, a novel vasodilator, compared with those of cromakalim, pinacidil and nifedipine in rat aorta. Eur J Pharmacol 1991;196:1-7.
18. Jinno Y, Kasai H, Ohta H, Nishikori K, Fukushima H, Ogawa N. Contribution of cyclic GMP formation to KRN2391-induced relaxation in coronary artery of the pig. Br J Pharmacol 1992;106:906-9.
19. Kawahara J, Kashiwabara T, Ogawa N, Okada Y, Izawa T. Antihypertensive properties of KRN4884, a novel long-lasting potassium channel opener. J Cardiovasc Pharmacol 1999;33:292-4.
20. + channel opener, on ionic currents in rabbit femoral arterial myocytes. J Pharmacol Sci 2003;93:289-98.
21. + channel opener, KRN4884, and related compounds in porcine coronary artery. Gen Pharmacol 1996;27:985-9.
22. + channel openers in guinea-pig ventricular cells. Br J Pharmacol 1997;120:1568-74.
23. Wareing M, Greenwood SL, Taggart MJ, Baker PN. Vasoactive responses of veins isolated from the human placental chorionic plate. Placenta 2003;24:790-6.
24. Wareing M, Crocker IP, Warren AY, Taggart MJ, Baker PN. Characterization of small arteries isolated from the human placental chorionic plate. Placenta 2002;23:400-9.
25. Kleiner-Assaf A, Jaffa AJ, Elad D. Hemodynamic model for analysis of Doppler ultrasound indexes of umbilical blood flow. Am J Physiol 1999;276:H2204-14.
26. Nakajima T, Nakajima S, Izawa T, Kashiwabara T, Munezuka Y, Cyanoamidines. II. Synthesis and pharmacological activity of N-arylalkyl-N′-cyano-3-pyridinecarboxamidines. Chem Pharm Bull (Tokyo) 1994;42:2483-90.
27. Kashiwabara T, Ogawa N, Izawa T, Fukushima H. Differential vasodilator properties of KRN2391, cromakalim, nitroglycerin and nifedipine in rabbit isolated femoral artery and vein. Br J Pharmacol 1994;111:278-82.
28. Miwa A, Kaneta S, Motoki K, Jinno Y, Kasai H, Okada Y et al. Vasorelaxant mechanism of KRN2391 and nicorandil in porcine coronary arteries of different sizes. Br J Pharmacol 1993;109:632-6.
29. Corbin JD, Francis SH. Pharmacology of phosphodiesterase-5 inhibitors. Int J Clin Pract 2002;56:453-9.
30. Bivalacqua TJ, Champion HC, Hellstrom WJ, Kadowitz PJ. Pharmacotherapy for erectile dysfunction. Trends Pharmacol Sci 2000;21:484-9.
31. Izumi H, Jinno Y, Kaneta S, Tanaka Y, Okada Y, Izawa T et al. Effects of KRN4884, a novel K channel opener, on the cardiovascular system in anesthetized dogs: a comparison with levcromakalim, nilvadipine, and nifedipine. J Cardiovasc Pharmacol 1995;26:189-97.