Mechanism of flavin reduction in class 2 dihydroorotate dehydrogenases

Biochemistry

Volumn 45, Issue 50, 2006, Pages 14926-14932

  Fagan, Rebecca L ^a   Nelson, Maria N ^a   Pagano, Paul M ^a   Palfey, Bruce A ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL BONDS; ESCHERICHIA COLI; HYDRIDES; ISOTOPES; PH; QUANTUM THEORY; RATE CONSTANTS;

DEPROTONATION; FLAVIN REDUCTION; HOMO SAPIENS; QUANTUM MECHANICAL TUNNELING;

ENZYMES;

BACTERIAL ENZYME; DIHYDROOROTATE DEHYDROGENASE; DIHYDROOROTATE DEHYDROGENASE 2; DIHYDROOROTIC ACID DERIVATIVE; ESCHERICHIA COLI PROTEIN; OROTIC ACID; PROTON; QUERCETIN; SERINE;

ARTICLE; COVALENT BOND; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME MECHANISM; ENZYME METABOLISM; ENZYME MODIFICATION; ESCHERICHIA COLI; HUMAN; ISOTOPE ANALYSIS; NONHUMAN; OXIDATION KINETICS; PH; PKA; PRIORITY JOURNAL; QUANTUM MECHANICS; REDUCTION KINETICS;

BINDING SITES; CATALYSIS; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; FLAVIN MONONUCLEOTIDE; HUMANS; HYDROGEN-ION CONCENTRATION; MODELS, CHEMICAL; OROTIC ACID; OXIDATION-REDUCTION; OXIDOREDUCTASES ACTING ON CH-CH GROUP DONORS; SERINE; SUBSTRATE SPECIFICITY;

ESCHERICHIA COLI; HOMO SAPIENS;

EID: 33845567507     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi060919g     Document Type: Article

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