Proton transfer from the C5-proR/proS positions of L-dihydroorotate: General-base catalysis, isotope effects, and internal return

Journal of the American Chemical Society

Volumn 121, Issue 51, 1999, Pages 12054-12062

  Argyrou, Argyrides ^a   Washabaugh, Michael W ^a,b  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIHYDROOROTATE DEHYDROGENASE;

ARTICLE; CATALYSIS; ENZYME MECHANISM; PROTON TRANSPORT; SOLVATION; STEREOCHEMISTRY; THERMODYNAMICS;

EID: 0033616090     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja992753v     Document Type: Article

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