A second dihydroorotate dehydrogenase (type A) of the human pathogen Enterococcus faecalis: Expression, purification, and steady-state kinetic mechanism

Archives of Biochemistry and Biophysics

Volumn 377, Issue 1, 2000, Pages 178-186

  Marcinkeviciene, Jovita ^a   Jiang, Wenjun ^a   Locke, Gregory ^a   Kopcho, Lisa M ^a   Rogers, M John ^a   Copeland, Robert A ^a  

^a DUPONT COMPANY   (United States)

Author keywords

DHODase A; Enterococcus faecalis; Quinone reduction; Steady state kinetic mechanism

Indexed keywords

DIHYDROOROTATE DEHYDROGENASE; MENADIONE; OROTIC ACID;

ARTICLE; BINDING SITE; ENTEROCOCCUS; ENTEROCOCCUS FAECALIS; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME PURIFICATION; GENE EXPRESSION; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; STEADY STATE;

BACTERIA (MICROORGANISMS); ENTEROCOCCUS FAECALIS; LACTOCOCCUS LACTIS;

EID: 0034193174     PISSN: 00039861     EISSN: None     Source Type: Journal    
DOI: 10.1006/abbi.2000.1769     Document Type: Article

References (32)

1. Hammond D., Burchell J., Pudney M. Mol. Biochem. Parasitol. 14:1985;97-109.
2. Chen S. F., Perrella F. W., Behrens D. L., Papp L. Cancer Res. 52:1992;3521-3527.
3. Ruckermann K., Fairbanks L. D., Carrey E. A., Hawrylowicz C. M., Richards D. F., Kirschbaum B., Simmonds H. A. J. Biol. Chem. 273:1998;21682-21691.
4. Davis J. P., Cain G. A., Pitts W. J., Magolda R. L., Copeland R. A. Biochemistry. 35:1996;1270-1273.
5. Bruneu J. M., Yea C. M., Spinella-Jaegle S., Fudali C., Woodward K., Robson P. A., Sautes C., Westwood R., Kuo E. A., Williamson R. A., Ruuth E. Biochem. J. 336:1998;299-303.
6. Rowland P., Nielsen F. S., Jensen K. F., Larsen S. Structure. 5:1997;239-252.
7. Larsen J., Jensen K. F. Eur. J. Biochem. 151:1985;59-65.
8. Krungkrai J., Cerami A., Henderson G. B. Biochim. Biophys. Acta. 1243:1995;351-360.
9. Hines V., Keys L. D. III, Johnston M. J. Biol. Chem. 261:1986;11386-11392.
10. Andersen P. S., Jansen P. J. G., Hammer K. J. Bacteriol. 176:1994;3975-3982.
11. Nagy M., Lacroute F., Thomas D. Proc. Natl. Acad. Sci. USA. 89:1992;8966-8970.
12. Nielsen F. S., Andersen P. S., Jensen K. F. J. Biol. Chem. 271:1996;29359-29365.
13. Bjornberg O., Rowland P., Larsen S., Jensen K. F. Biochemistry. 36:1997;16197-16205.
14. Hines V., Johnston M. Biochemistry. 28:1989;1222-1226.
15. Bjornberg O., Gruner A.-C., Roepstorff P., Jensen K. F. Biochemistry. 38:1999;2899-2908.
16. Marcinkeviciene J., Tinney L. M., Wang K. H., Rogers J. M., Copeland R. A. Biochemistry. 38:1999;13129-13137.
17. Li X., Weinstock G. M., Murray B. E. J. Bacteriol. 177:1995;6866-6873.
18. Lennon B. W., Williams C. H. Jr. Biochemistry. 36:1997;9464-9477.
19. Cleland W. W. Methods Enzymol. 63:1979;103-138.
20. Rowland P., Bjornberg O., Nielsen F. S., Jensen K. F., Larsen S. Protein. Sci. 7:1998;1269-1279.
21. Tedeschi G., Negri A., Mortarino M., Ceciliani F., Simonic T., Faotto G., Ronchi S. J. Biochem. 239:1996;427-433.
22. Newton N. A., Cox G. B., Gibson F. Biochim. Biophys. Acta. 244:1971;155-166.
23. Andrews S., Cox G. B., Gibson F. Biochim. Biophys. Acta. 396:1977;229-241.
24. Singh A. P., Bragg P. D. Biochim. Biophys. Acta. 396:1975;229-241.
25. Segel I. H. Enzyme Kinetics. 1993;Wiley, New York/Chichester/Brisbane/Toronto/Singapore. p. 626-634.
26. Podschun B., Cook P., Schnackerz K. J. Biol. Chem. 265:1990;12966-12972.
27. Gibson Q. H., Swoboda B. E. P., Massey V. J. Biol. Chem. 239:1964;3927-3934.
28. Lockridge O., Massey V., Sullivan P. A. J. Biol. Chem. 247:1972;8097-8106.
29. Northrop D. B. J. Biol. Chem. 244:1969;5808-5819.
30. Marcinkeviciene J., Blanchard J. S. Biochemistry. 34:1995;6621-6627.
31. Cenas N., Arscott L. D., Williams C. H. Jr., Blanchard J. S. Biochemistry. 33:1994;2509-2515.
32. Karplus A., Pai E. F., Schulz G. E. Eur. J. Biochem. 178:1989;693-703.