Substrate binding and catalytic mechanism of human choline acetyltransferase

Biochemistry

Volumn 45, Issue 49, 2006, Pages 14621-14631

  Kim, Ae Ri ^a   Rylett, R J ^a,b   Shilton, Brian H ^a  

^a WESTERN UNIVERSITY   (Canada)

^b ROBARTS RESEARCH INSTITUTE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; CATALYSIS; CHEMICAL MODIFICATION; NEUROLOGY; SUBSTRATES;

BINARY COMPLEXES; CHOLINE ACETYLTRANSFERASE; NEURONS; NEUROTRANSMITTER ACETYLCHOLINE;

ENZYME IMMOBILIZATION;

ACETIC ACID DERIVATIVE; ACETYL COENZYME A; ACETYLCHOLINE; CHOLINE; CHOLINE ACETYLTRANSFERASE; FUNCTIONAL GROUP; NEUROTRANSMITTER; PHOSPHATE; SERINE DEHYDRATASE; TRIMETHYLAMMONIUM SALT DERIVATIVE;

ARTICLE; CATALYSIS; CHOLINERGIC NERVE CELL; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; HUMAN; MICHAELIS MENTEN KINETICS; MOLECULAR DYNAMICS; MOLECULAR STABILITY; PHOSPHORYLATION; PRIORITY JOURNAL; SURFACE PROPERTY; SYNTHESIS;

AMINO ACID SEQUENCE; BINDING SITES; CATALYSIS; CHOLINE; CHOLINE O-ACETYLTRANSFERASE; COENZYME A; CRYSTALLOGRAPHY, X-RAY; ENTROPY; HUMANS; MODELS, MOLECULAR; PROTEIN CONFORMATION; RECOMBINANT PROTEINS;

EID: 33845448089     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi061536l     Document Type: Article

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