Trisomy 8 as sole cytogenetic abnormality in a case of chronic lymphocytic leukemia

Cancer Genetics and Cytogenetics

Volumn 172, Issue 1, 2007, Pages 66-69

  Lau, Lai Ching ^a   Kee, Su Keyau ^a   Tien, Sim Leng ^a   Koh Mickey, Boon Chai ^a  

^a SINGAPORE GENERAL HOSPITAL   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BLOOD; BLOOD SAMPLING; BONE MARROW; CASE REPORT; CHROMOSOME ABERRATION; CHROMOSOME ANALYSIS; CHRONIC LYMPHATIC LEUKEMIA; FLUORESCENCE IN SITU HYBRIDIZATION; GENE PROBE; HUMAN; INTERPHASE; KARYOTYPE; MALE; PRIORITY JOURNAL; PROGNOSIS; TRISOMY 8;

BONE MARROW; CHROMOSOMES, HUMAN, PAIR 8; DNA PROBES; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; INTERPHASE; KARYOTYPING; LEUKEMIA, LYMPHOCYTIC, CHRONIC; MALE; MIDDLE AGED; TRISOMY;

EID: 33845428583     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cancergencyto.2006.05.019     Document Type: Article

References (18)

1. Montserrat E., and Rozman C. Chronic lymphocytic leukemia: present status. Ann Oncol 6 (1995) 219-235
2. Nair C.N., Chougule A., Dhond S., Goyal R., Parikh P.M., Pai S., Telang D., and Advani S.H. Trisomy 12 in chromic lymphocytic leukemia-geographical variation. Leuk Res 22 (1998) 313-317
3. Criel A., Wlodarska I., Meeus P., Stul M., Louwagie A., Van Hoof A., Hidajat M., Mecucci C., and Van den Berghe H. Trisomy 12 is uncommon in typical chronic lymphocytic leukemia. Br J Haematol 87 (1994) 523-528
4. Matutes E., Oscier D., Garcia-Marco J., Ellis J., Copplestone A., Gillingham R., Hamblin T., Lens D., Swansbury G.J., and Catovsky D. Trisomy 12 defines a group of CLL with atypical morphology: correlation between cytogenetic, clinical and laboratory features in 544 patients. Br J Haematol 92 (1996) 382-388
5. Mould S., Gardiner A., Corcoran M., and Oscier D.G. Trisomy 12 and structural abnormalities of 13q14 occurring in the same clone in chronic lymphocytic leukemia. Br J Haematol 92 (1996) 389-392
6. Liso V., Capalbo S., Lapietra A., Pavone V., Guarini A., and Specchia G. Evaluation of trisomy 12 by fluorescence in situ hybridization in peripheral blood, bone marrow and lymph nodes of patients with B-cell chronic lymphocytic leukemia. Haematologica 84 (1999) 212-217
7. Juliusson G., Oscier D.G., Fitchett M., Ross F.M., Phil D., Stockdill G., Mackie M.J., Parker A.C., Castoldi G.L., Cuneo A., Knuutila S., Elonen E., and Gahrton G. Prognostic subgroups in B-cell chronic lymphocytic leukemia defined by specific chromosomal abnormalities. N Engl J Med 323 (1990) 720-724
8. Karnolsky I.N. Cytogenetic abnormalities in chronic lymphocytic leukemia. Folia Med (Plovdiv) 42 (2000) 5-10
9. Cheson B.D., Bennett J.M., Grever M., Kay N., Keating M.J., O'Brien S., and Rai K.R. National Cancer Institute-Sponsored Working Group guidelines for chronic lymphocytic leukemia: revised guidelines for diagnosis and treatment. Blood 87 (1996) 4990-4997
10. Dighiero G., Travade P., Chevret S., Fenaux P., Chastang C., Binet J.-L., and the French Cooperative Group on CLL. B cell chronic lymphocytic leukemia: present status and future directions. Blood 78 (1991) 1901-1914
11. Emilia G., Temperani P., Giacobbi F., and Vaccari P. Chromosome abnormalities in chronic lymphocytic leukemia. Leuk Res 21 (1997) 691-692
12. Oscier D.G., Gardiner A.C., Mould S.J., Glide S., Davis Z.A., Ibbotson R.E., Corcoran M.M., Chapman R.M., Thomas P.W., Copplestone J.A., Orchard J.A., and Hamblin T.J. Multivariate analysis of prognostic factors in CLL: clinical stage, IGVH gene, mutational status, and loss or mutation of the p53 gene are independent prognostic factors. Blood 100 (2002) 1177-1184
13. H mutation status, CD38 expression level, genomic aberrations, and survival in chronic lymphocytic leukemia. Blood 100 (2002) 1410-1416
14. Mrozek K., Heerema N.A., and Bloomfield C.D. Cytogenetics in acute leukemia. Blood Rev 18 (2004) 115-136
15. Paulsson K., Sall T., Fioretos T., Mitelman F., and Johansson B. The incidence of trisomy 8 as a sole chromosomal aberration in myeloid malignancies varies in relation to gender, age, prior iatrogenic genotoxic exposure, and morphology. Cancer Genet Cytogenet 130 (2001) 160-165
16. Wang Y., Hopwood V.L., Hu P., Lennon A., Osterberger J., and Glassman A. Determination of secondary chromosomal aberrations of chronic myelocytic leukemia. Cancer Genet Cytogenet 153 (2004) 53-56
17. Aviv H., Tang D., Das K., Harrison J.S., Hameed M., and Varma M. Simultaneous appearance of trisomy 8 and trisomy 12 in different cell populations in a patient with untreated B cell chronic lymphocytic leukemia and myelodysplasia. Leuk Lymph 45 (2004) 1279-1283
18. Oo T.H. Trisomy 8 in a newly diagnosed chronic lymphocytic leukemia. Cancer Genet Cytogenet 156 (2005) 94-95