Enhancer and promoter activity in the JH to IGHM intron of the Pekin duck, Anas platyrhynchos

Developmental and Comparative Immunology

Volumn 31, Issue 3, 2007, Pages 286-295

  Lundqvist, Mats L ^a   McElveen, Bryan R ^a   Middleton, Darlene L ^a   Warr, Gregory W ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Aves; Ducks; Evolution; I exon promoter; Immunoglobulin genes; Transcriptional enhancer

Indexed keywords

ARTICLE; B LYMPHOCYTE; CHICKEN; CONTROLLED STUDY; DUCK; ENHANCER REGION; EVOLUTION; FOWL; GENE; GENE CONSTRUCT; IGHM GENE; INTRON; JH GENE; MAMMAL CELL; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN MOTIF; SIMIAN VIRUS 40; T LYMPHOCYTE; TRANSCRIPTION REGULATION;

ANAS; ANAS PLATYRHYNCHOS; AVES; MAMMALIA;

EID: 33845411287     PISSN: 0145305X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dci.2006.06.004     Document Type: Article

References (40)

1. Calame K., and Sen R. Transcription of immunoglobulin genes. In: Honjo T., Alt F.W., and Neuberger M.S. (Eds). Molecular biology of B cells (2004), Elsevier Science, Amsterdam 83-100
2. Banerji J., Olson L., and Schaffner W. A lymphocyte-specific cellular enhancer is located downstream of the joining region in immunoglobulin heavy chain genes. Cell 33 (1983) 729-740
3. Mercola M., Wang X.F., Olsen J., and Calame K. Transcriptional enhancer elements in the mouse immunoglobulin heavy chain locus. Science 221 (1983) 663-665
4. Gillies S.D., Morrison S.L., Oi V.T., and Tonegawa S. A tissue-specific transcription enhancer element is located in the major intron of a rearranged immunoglobulin heavy chain gene. Cell 33 (1983) 717-728
5. Nikolajczyk B.S., Dang W., and Sen R. Mechanisms of mu enhancer regulation in B lymphocytes. Cold Spring Harb Symp Quant Biol 64 (1999) 99-107
6. Khamlichi A.A., Pinaud E., Decourt C., Chauveau C., and Cogne M. The 3′ IgH regulatory region: a complex structure in a search for a function. Adv Immunol 75 (2000) 317-345
7. Bottaro A., Young F., Chen J., Serwe M., Sablitzky F., and Alt F.W. Deletion of the IgH intronic enhancer and associated matrix-attachment regions decreases, but does not abolish, class switching at the mu locus. Int Immunol 10 (1998) 799-806
8. Bachl J., and Olsson C. Hypermutation targets a green fluorescent protein-encoding transgene in the presence of immunoglobulin enhancers. Eur J Immunol 29 (1999) 1383-1389
9. Bachl J., Olsson C., Chitkara N., and Wabl M. The Ig mutator is dependent on the presence, position, and orientation of the large intron enhancer. Proc Natl Acad Sci USA 95 (1998) 2396-2399
10. Serwe M., and Sablitzky F. V(D)J recombination in B cells is impaired but not blocked by targeted deletion of the immunoglobulin heavy chain intron enhancer. Embo J 12 (1993) 2321-2327
11. Cogne M., and Birshtein B.K. Regulation of class switch recombination. In: Honjo T., Alt F.W., and Neuberger M.S. (Eds). Molecular biology of B cells (2004), Elsevier Science, Amsterdam 289-305
12. Cogne M., Lansford R., Bottaro A., Zhang J., Gorman J., Young F., et al. A class switch control region at the 3′ end of the immunoglobulin heavy chain locus. Cell 77 (1994) 737-747
13. Ellestad K.K., and Magor B.G. Evolution of transcriptional enhancers in the immunoglobulin heavy-chain gene: functional characteristics of the zebrafish Emu3′ enhancer. Immunogenetics 57 (2005) 129-139
14. Magor B.G., Ross D.A., Middleton D.L., and Warr G.W. Functional motifs in the IgH enhancer of the channel catfish. Immunogenetics 46 (1997) 192-198
15. Magor B.G., Ross D.A., Pilstrom L., and Warr G.W. Transcriptional enhancers and the evolution of the IgH locus. Immunol Today 20 (1999) 13-17
16. Magor B.G., Wilson M.R., Miller N.W., Clem L.W., Middleton D.L., and Warr G.W. An Ig heavy chain enhancer of the channel catfish Ictalurus punctatus: evolutionary conservation of function but not structure. J Immunol 153 (1994) 5556-5563
17. Cioffi C.C., Middleton D.L., Wilson M.R., Miller N.W., Clem L.W., and Warr G.W. An IgH enhancer that drives transcription through basic helix-loop-helix and Oct transcription factor binding motifs. Functional analysis of the E(mu)3′ enhancer of the catfish. J Biol Chem 276 (2001) 27825-27830
18. Amemiya C.T., and Litman G.W. Complete nucleotide sequence of an immunoglobulin heavy-chain gene and analysis of immunoglobulin gene organization in a primitive teleost species. Proc Natl Acad Sci USA 87 (1990) 811-815
19. Litman G.W., Flajnik M.F., and Warr G.W. Diverse forms of immunoglobulin genes in lower vertebrates. In: Honjo T., Alt F.W., and Neuberger M.S. (Eds). Molecular biology of B cells (2004), Elsevier Science, Amsterdam 417-432
20. Wilson M., Bengten E., Miller N.W., Clem L.W., Du Pasquier L., and Warr G.W. A novel chimeric Ig heavy chain from a teleost fish shares similarities to IgD. Proc Natl Acad Sci USA 94 (1997) 4593-4597
21. Hikima J., Lennard M.L., Wilson M.R., Miller N.W., Clem L.W., and Warr G.W. Conservation and divergence of the Emu3′ enhancer in the IGH locus of teleosts. Immunogenetics 58 (2006) 226-234
22. Rao E., Dang W., Tian G., and Sen R. A three-protein-DNA complex on a B cell-specific domain of the immunoglobulin mu heavy chain gene enhancer. J Biol Chem 272 (1997) 6722-6732
23. Lee S., Kohane I., and Kasif S. Genes involved in complex adaptive processes tend to have highly conserved upstream regions in mammalian genomes. BMC Genom 6 (2005) 168
24. Ohta Y, Flajnik M, IgD, like IgM, is a primordial immunoglobulin class perpetuated in most jawed vertebrates. Proc Nat Acad Sci (USA) 2006;103:10723-8.
25. Lundqvist M.L., Middleton D.L., Hazard S., and Warr G.W. The immunoglobulin heavy chain locus of the duck. Genomic organization and expression of D, J, and C region genes. J Biol Chem 276 (2001) 46729-46736
26. Zhao Y., Rabbani H., Shimizu A., and Hammarstrom L. Mapping of the chicken immunoglobulin heavy-chain constant region gene locus reveals an inverted alpha gene upstream of a condensed upsilon gene. Immunology 101 (2000) 348-353
27. McCormack W.T., Tjoelker L.W., and Thompson C.B. Avian B-cell development: generation of an immunoglobulin repertoire by gene conversion. Annu Rev Immunol 9 (1991) 219-241
28. Schatz D.G., Oettinger M.A., and Schlissel M.S. V(D)J recombination: molecular biology and regulation. Annu Rev Immunol 10 (1992) 359-383
29. Honjo T., Kinoshita K., and Muramatsu M. Molecular mechanism of class switch recombination: linkage with somatic hypermutation. Annu Rev Immunol 20 (2002) 165-196
30. Baba T.W., Giroir B.P., and Humphries E.H. Cell lines derived from avian lymphomas exhibit two distinct phenotypes. Virology 144 (1985) 139-151
31. Baba T.W., and Humphries E.H. Differential response to avian leukosis virus infection exhibited by two chicken lines. Virology 135 (1984) 181-188
32. Calnek B.W., Lucioi B., and Schat K.A. Pathogenesis of Marek's Disease virus-induced lesions. 2. Influence of virus strain and host genotype. In: Kato S., Huriushi T., Mikami T., and Hirari K. (Eds). Advances in Marek's Disease Research (1988), Japanese Association on Marek's Disease, Osaka 324-330
33. Su L.K., and Kadesch T. The immunoglobulin heavy-chain enhancer functions as the promoter for I mu sterile transcription. Mol Cell Biol 10 (1990) 2619-2624
34. Lennon G.G., and Perry R.P. C mu-containing transcripts initiate heterogeneously within the IgH enhancer region and contain a novel 5′-nontranslatable exon. Nature 318 (1985) 475-478
35. Arakawa H., Furusawa S., Ekino S., and Yamagishi H. Immunoglobulin gene hyperconversion ongoing in chicken splenic germinal centers. Embo J 15 (1996) 2540-2546
36. Lanning D., Osborne B.A., and Knight K.L. Immunoglobulin genes generation of antibody repertoires in higher vertebrates: a key role for GALT. In: Honjo T., Alt F.W., and Neuberger M.S. (Eds). Molecular biology of B cells (2004), Elsevier Science, Amsterdam 433-448
37. Corcoran D.L., Feingold E., and Benos P.V. FOOTER: a web tool for finding mammalian DNA regulatory regions using phylogenetic footprinting. Nucleic Acids Res 33 (2005) W442-W446
38. von Bubnoff A., Peiffer D.A., Blitz I.L., Hayata T., Ogata S., Zeng Q., et al., Phylogenetic footprinting and genome scanning identify vertebrate BMP response elements and new target genes. Dev Biol 281 (2005) 210-226
39. Stavnezer J., Kinoshita K., Muramatsu M., and Honjo T. Molecular mechanisms of class switch recombination. In: Honjo T., Alt F.W., and Neuberger M.S. (Eds). Molecular biology of B cells (2004), Elsevier Science, Amsterdam 307-326
40. Lundqvist M.L., McElveen B.R., Middleton D.L., Chapman R., and Warr G.W. Evolution of antibody class switching: Identification and transcriptional control of an Iupsilon exon in the Duck (Anas platyrhynchos). Dev Comp Immunol 30 (2006) 575-587