Implications of High-Risk Family Studies for Prevention of Depression

American Journal of Preventive Medicine

Volumn 31, Issue 6 SUPPL. 1, 2006, Pages 126-135

  Avenevoli, Shelli ^a   Merikangas, Kathleen Ries ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANXIETY DISORDER; BEHAVIOR DISORDER; COMORBIDITY; CONDUCT DISORDER; DEPRESSION; DISEASE PREDISPOSITION; EMOTIONAL DISORDER; ENVIRONMENTAL FACTOR; FAMILY; GENETIC RISK; GENETIC SUSCEPTIBILITY; HIGH RISK POPULATION; HUMAN; MOOD DISORDER; PROGENY; REVIEW; RISK ASSESSMENT; SOCIAL PSYCHIATRY; SUBSTANCE ABUSE;

ADOLESCENT; CHILD; CHILD OF IMPAIRED PARENTS; COMORBIDITY; DEPRESSION; DEPRESSIVE DISORDER, MAJOR; FAMILY; FAMILY RELATIONS; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MODELS, PSYCHOLOGICAL; RISK FACTORS;

EID: 33845407794     PISSN: 07493797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.amepre.2006.07.003     Document Type: Review

References (93)

1. Judd L.L., Paulus M.P., Wells K.B., and Rapaport M.H. Socioeconomic burden of subsyndromal depressive symptoms and major depression in a sample of the general population. Am J Psychiatry 153 (1996) 1411-1417
2. Murray C.J.L., and Lopez A.D. The global burden of disease and injury series. Volume 1: A comprehensive assessment of mortality and disability from diseases, injuries and risk factors in 1990 and projected to 2020 (1996), Harvard School of Public Health on behalf of the World Health Organization and the World Bank, Harvard University Press, Cambridge MA
3. Ustun T.B., Rehm J., Chatterji S., et al. Multiple-informant ranking of the disabling effects of different health conditions in 14 countries. Lancet 354 (1999) 111-115
4. Merikangas K.R., and Avenevoli S. Epidemiology of mood and anxiety disorders in children and adolescents. In: Tsuang M.T., and Tohen M. (Eds). Textbook in psychiatric epidemiology. 2nd ed (2002), Wiley-Liss, New York 657-704
5. Merikangas K.R., Avenevoli S., Dierker L., and Grillon C. Vulnerability factors among children at risk for anxiety disorders. Biol Psychiatry 46 (1999) 523-535
6. Beardslee W.R., Bemporad J., Keller M.B., and Klerman G.L. Children of parents with major affective disorder: a review. Am J Psychiatry 140 (1983) 825-832
7. Beardslee W.R., Versage E.M., and Gladstone T.R.G. Children of affectively ill parents: a review of the past 10 years. J Am Acad Child Adolesc Psychiatry 37 (1999) 1134-1141
8. Downey G., and Coyne J.C. Children of depressed parents: an integrative review. Psychol Bull 108 (1990) 50-76
9. Rice F., Harold G., and Thapar A. The genetic aetiology of childhood depression: a review. J Child Psychol Psychiatry 43 (2002) 65-79
10. Beardslee W.R., Keller M.B., Lavori P.W., Klerman G.K., Dorer D.J., and Samuelson H. Psychiatric disorder in adolescent offspring of parents with affective disorders in a nonreferred sample. J Affect Disord 15 (1988) 313-322
11. Beardslee W.R., Keller M.B., Lavori P.W., Staley J.E., and Sacks N. The impact of parental affective disorders on depression in offspring: a longitudinal follow-up in a nonreferred sample. J Am Acad Child Adolesc Psychiatry 32 (1993) 723-730
12. Lieb R., Isensee B., Hofler M., Pfister H., and Wittchen H.U. Parental major depression and the risk of depression and other mental disorders in offspring: a prospective-longitudinal community study. Arch Gen Psychiatry 59 (2002) 365-374
13. Klein D.N., Lewinsohn P.M., Seeley J.R., and Rohde P. A family study of major depressive disorder in a community sample of adolescents. Arch Gen Psychiatry 58 (2001) 13-20
14. Merikangas K.R., Prusoff B.A., and Weissman M.M. Parental concordance for affective disorders: psychopathology in offspring. J Affect Disord 15 (1988) 279-290
15. Weissman M.M., Wickramaratne P., Nomura Y., et al. Families at high and low risk for depression: a 3-generation study. Arch Gen Psychiatry 62 (2005) 29-36
16. Hammen C., Burge D., Burney E., and Adrian C. Longitudinal study of diagnosis in children of women with unipolar and bipolar affective disorder. Arch Gen Psychiatry 47 (1990) 1112-1117
17. Weissman M.M., Fendrich M., Warner V., and Wickramaratne P. Incidence of psychiatric disorder in offspring at high and low risk for depression. J Am Acad Child Adolesc Psychiatry 31 (1992) 640-648
18. Weissman M.M., Warner V., Wickramaratne P., Moreau D., and Olfson M. Offspring of depressed parents: ten years later. Arch Gen Psychiatry 54 (1997) 932-940
19. Sullivan P.F., Neale M.C., and Kendler K.S. Genetic epidemiology of major depression: review and meta-analysis. Am J Psychiatry 157 (2000) 1552-1562
20. Warner V., Mufson L., and Weissman M.M. Offspring at high risk for depression and anxiety: mechanisms of psychiatric disorder. J Am Acad Child Adolesc Psychiatry 34 (1995) 786-797
21. Harrington R., Rutter M., Weissman M., et al. Psychiatric disorders in the relatives of depressed probands. I. Comparison of prepubertal, adolescent and early adult onset cases. J Affect Disord 42 (1997) 9-22
22. Silberg J., Pickles A., and Rutter M. The influence of genetic factors and life stress on depression among adolescent girls. Arch Gen Psychiatry 56 (1999) 225-232
23. Wickramaratne P., and Weissman M.M. Onset of psychopathology in offspring by developmental phase and parental depression. J Am Acad Child Adolesc Psychiatry 37 (1998) 933-942
24. Weissman M.M., Wolk S., and Wickramaratne P. Children with pre-pubertal onset major depressive disorder and anxiety grown up. Arch Gen Psychiatry 56 (1999) 794-801
25. Hammen C., and Brennan P.A. Severity, chronicity, and timing of maternal depression and risk for adolescent offspring diagnosis in a community sample. Arch Gen Psychiatry 60 (2003) 253-258
26. Lieb R., Isensee B., Hofler M., and Wittchen H.-U. Parental depression and depression in offspring: evidence for familial characteristics and subtypes?. J Psychiatric Res 36 (2002) 237-246
27. Eley T.C., and Plomin R. Genetic analyses of emotionality. Curr Opin Neurobiol 7 (1997) 279-284
28. Murray K.T., and Sines J.O. Parsing the genetic and nongenetic variance in children's depressive behavior. J Affect Disord 38 (1996) 23-34
29. O'Connor T.G., Neiderhiser J.M., Neiderhiser D.R., Hetherington E.M., and Plomin R. Genetic contributions to continuity, change, and co-occurrence of antisocial and depressive symptoms in adolescence. J Child Psychol Psychiatry 39 (1998) 323-336
30. Thapar A., and McGuffin P. A twin study of depressive symptoms in childhood. Br J Psychiatry 165 (1994) 259-265
31. Thapar A., and McGuffin P. Are anxiety symptoms in childhood heritable. J Child Psychol Psychiatry 36 (1995) 439-447
32. Thapar A., and McGuffin P. Anxiety and depressive symptoms in childhood: a genetic study of comorbidity. J Child Psychol Psychiatry 38 (1997) 651-656
33. Scourfield J., Rice F., Thapar A., Harold G.T., Martin N., and McGuffin P. Depressive symptoms in children and adolescents: changing aetiological influences with development. J Child Psychol Psychiatry 44 (2003) 968-976
34. Kendler K.S., Neale M.C., Kessler R.C., Heath A.C., and Eaves L.J. The lifetime history of major depression in women. Arch Gen Psychiatry 50 (1993) 863-870
35. Eley T.C., Deater-Deckard K., Fombinne E., Fulker D.W., and Plomin R. An adoption study of depressive symptoms in middle childhood. J Child Psychol Psychiatry 39 (1998) 337-345
36. Van den Oord E.J., Boomsma I., and Verhulst F.C. A study of problem behavior in 10- to 15-year-old biologically related and unrelated international adoptees. Behav Genet 24 (1994) 193-205
37. Merikangas K.R., and Risch N. Will the genomics revolution revolutionize psychiatry?. Am J Psychiatry 160 (2003) 625-635
38. Carter A.S., Garrity-Rokous F.E., Chazan-Cohen R., Little C., and Briggs-Gowen M.J. Maternal depression and comorbidity: predicting early parenting, attachment security, and toddler social-emotional problems and competencies. J Am Acad Child Adolesc Psychiatry 40 (2001) 18-26
39. Goodman S.H., and Gotlib I.H. Risk for psychopathology in the children of depressed mothers: a developmental model for understanding mechanisms of transmission. Psychol Rev 106 (1999) 458-490
40. Brennan P.A., Le Brocque R., and Hammen C. Maternal depression, parent-child relationships, and resilient outcomes in adolescence. J Am Acad Child Adolesc Psychiatry 42 (2003) 1469-1477
41. McGuffin P., Katz R., and Bebbington P. The Camberwell Collaborative Depression Study. III. Depression and adversity in the relatives of depressed probands. Br J Psychiatry 152 (1988) 775-782
42. Hammen C., Shih J.H., and Brennan P.A. Intergenerational transmission of depression: test of an interpersonal stress model in a community sample. J Consult Clin Psychol 72 (2004) 511-522
43. Hammen C., Brennan P.A., and Shih J.H. Family discord and stress predictors of depression and other disorders in adolescent children of depressed and nondepressed women. J Am Acad Child Adolesc Psychiatry 43 (2004) 994-1002
44. Farmer A, Harris T, Redman K, Sadler S, Mahmood A, McGuffin P. Cardiff depression study. A sib-pair study of life events and familiality in major depression. Br J Psychiatry 200;176:150-5.
45. Radke-Yarrow M., and Klimes-Dougan B. Parental depression and offspring disorders: a developmental perspective. In: Goodman S.H., and Gotlib I.H. (Eds). Children of depressed parents: mechanisms of risk and implications for treatment (2002), American Psychological Association, Washington DC 155-173
46. Radke-Yarrow M., Martinez P., and Mayfield A Ronsaville D. Children of depressed mothers: from early childhood to maturity (1998), Cambridge University Press, New York
47. Hammen C., Burge D., and Stansbury K. Relationship of mother and child variables to child outcomes in a high-risk sample: a causal modeling analysis. Dev Psychol 26 (1990) 24-30
48. Phares V., Duhig A.M., and Watkins M.M. Family context: fathers and other supports. In: Goodman S.H., and Gotlib I.H. (Eds). Children of depressed parents: mechanisms of risk and implications for treatment (2002), American Psychological Association, Washington DC 203-225
49. Biederman J., Rosenbaum J.F., Bolduc E.A., Faraone S.V., and Hirshfeld D.R. A high-risk study of young children of parents with panic disorder and agoraphobia with and without comorbid major depression. Psychiatry Res 37 (1991) 333-348
50. Pine D.S., Cohen P., Gurley D., Brook J., and Ma Y. The risk for early-adulthood anxiety and depressive disorders in adolescents with anxiety and depressive disorders. Arch Gen Psychiatry 55 (1998) 56-64
51. Johnson J.G., Cohen P., and Brook J.S. Associations between bipolar disorder and other psychiatric disorders during adolescence and early adulthood: a community-based longitudinal investigation. Am J Psychiatry 57 (2000) 1679-1681
52. Rohde P., Lewinsohn P.M., and Seeley J.R. Comorbidity of unipolar depression: II. Comorbidity with other mental disorders in adolescents and adults. J Abnorm Psychol 100 (1991) 214-222
53. Merikangas K.R. Comorbidity for anxiety and depression: review of family and genetic studies. In: Maser J.D., and Cloninger C.R. (Eds). Comorbidity of mood and anxiety disorders (1990), American Psychiatric Press, Washington DC 331-348
54. Weissman M.M. Evidence for comorbidity of anxiety and depression: family and genetic studies of children. In: Maser J.D., and Cloninger C.R. (Eds). Comorbidity of mood and anxiety disorders (1990), American Psychiatric Press, Washington DC 349-368
55. Warner V., Weissman M.M., Mufson L., and Wickramaratne P.J. Grandparents, parents, and grandchildren at high risk for depression: a three-generation study. J Am Acad Child Adolesc Psychiatry 38 (1999) 289-296
56. Beidel D., and Turner S. At risk for anxiety I: psychopathology in the offspring of anxious parents: a direct interview study. J Am Acad Child Adolesc Psychiatry 36 (1997) 918-924
57. Rende R., Warner V., Wickramarante P., and Weissman M.M. Sibling aggregation for psychiatric disorders in offspring at high and low risk for depression: 10-year follow-up. Psychol Med 29 (1999) 1291-1298
58. Avenevoli S., Stolar M., Li J., Dierker L., and Merikangas K.R. Comorbidity of depression in children and adolescents: models and evidence from a prospective high-risk family study. Biol Psychiatry 49 (2001) 1071-1081
59. Turner S.M., Beidel D.C., and Costello A. Psychopathology in the offspring of anxiety disorders patients. J Consult Clin Psychol 55 (1987) 229-235
60. McClellan J.M., Rubert M.P., Reichler R.J., and Sylvester C.E. Attention deficit disorder in children at risk for anxiety and depression. J Am Acad Child Adolesc Psychiatry 29 (1990) 534-539
61. Mufson L., Weissman M.M., and Warner V. Depression and anxiety in parents and children: a direct interview study. J Anxiety Disord 6 (1992) 1-13
62. Biederman J., Faraone S.V., Hirshfeld D.R., Friedman D., Robin J.A., and Rosenbaum J.F. Patterns of psychopathology and dysfunction in high-risk children of parents with panic disorder and major depression. Am J Psychiatry 158 (2001) 49-57
63. Weissman M.M., Wickramaratne P., Adams P.B., et al. The relationship between panic disorder and major depression: a new family study. Arch Gen Psychiatry 50 (1993) 767-780
64. Rende R., Wickramaratne P., Warner V., and Weissman M.M. Sibling resemblance for psychiatric disorders in offspring at high and low risk for depression. J Child Psychol Psychiatry 36 (1995) 1353-1363
65. Kendler K.S., Neale M.C., Kessler R.C., and Heath A.C. Major depression and generalized anxiety disorder: same genes, (partly) different environment?. Arch Gen Psychiatry 49 (1992) 716-722
66. Kendler K.S. Major depression and generalised anxiety disorder: same genes, (partly) different environments-revisited. Br J Psychiatry 168 (1996) 68-75
67. Roy M.A., Neale M.C., Pedersen N.L., Mathe A.A., and Kendler K.S. A twin study of generalized anxiety disorder and major depression. Psychol Med 25 (1995) 1037-1049
68. Silberg J.L., Rutter M., and Eaves L. Genetic and environmental influences on the temporal association between earlier anxiety and later depression in girls. Biol Psychiatry 49 (2001) 1040-1049
69. Angst J., Vollrath M., Merikangas K.R., and Ernst C. Comorbidity of anxiety and depression in the Zurich Cohort Study of young adults. In: Maser J.D., and Cloninger C.R. (Eds). Comorbidity of mood and anxiety disorders (1990), American Psychiatric Press, Washington DC 123-137
70. Harrington R., Rutter M., and Fombonne E. Developmental pathways in depression: multiple meanings, antecedents, and endpoints. Dev Psychopathol 8 (1996) 601-616
71. Torgensen S. A twin study perspective of the comorbidity of anxiety and depression. In: Maser J.D., and Cloninger C.R. (Eds). Comorbidity of mood and anxiety disorders (1990), American Psychiatric Press, Washington DC 367-378
72. Puig-Antich J., Goetz D., Davies M., et al. A controlled family history study of prepubertal major depressive disorder. Arch Gen Psychiatry 46 (1989) 406-418
73. Kim E.Y., and Miklowitz D.J. Childhood mania, attention deficit hyperactivity disorder and conduct disorder: a critical review of diagnostic dilemmas. Bipolar Disord 4 (2002) 215-225
74. Bowring M.A., and Kovacs M. Difficulties in diagnosing manic disorders among children and adolescents. J Am Acad Child Adol Psychiatry 31 (1992) 611-614
75. Garber J., and Martin N. Negative cognitions in offspring of depressed parents: mechanisms of risk. In: Goodman S.H., and Gotlib I.H. (Eds). Children of depressed parents: mechanisms of risk and implications for treatment (2002), American Psychological Association, Washington DC 121-153
76. Grillon C., Warner V., Hille J., et al. Families at high and low risk for depression: a three generation startle study. Biol Psychiatry 57 (2005) 953-960
77. Bruder G.E., Tenke C.E., Warner V., et al. Electroencephalographic measures of regional hemispheric activity in offspring at risk for depressive disorders. Biol Psychiatry 57 (2005) 328-335
78. Stoleru S., Nottelmann E.D., Belmont B., and Ronsaville D. Sleep problems in children of affectively ill mothers. J Child Psychol Psychiatry 38 (1997) 831-841
79. Ivanenko A., Crabtree V.M., and Gozal D. Sleep and depression in children and adolescents. Sleep Med Rev 9 (2005) 115-129
80. Ashman S.B., and Dawson G. Maternal depression, infant psychobiological development and risk for depression. In: Goodman S.H., and Gotlib I.H. (Eds). Children of depressed parents: mechanisms of risk and implications for treatment (2002), American Psychological Association, Washington DC 37-58
81. Zahn-Waxler C., Ianotti R., Cummings E.M., and Denham S. Antecedents of problem behaviors in children of depressed mothers. Dev Psychopathol 2 (1990) 271-291
82. Lyons-Ruth K., Lyubchik A., Wolfe R., and Bronfman E. Parental depression and child attachment: hostile and helpless profiles of parent and child behavior among families at risk. In: Goodman S.H., and Gotlib I.H. (Eds). Children of depressed parents: mechanisms of risk and implications for treatment (2002), American Psychological Association, Washington DC 89-120
83. Chassin L., Pitts S.C., DeLucia C., and Todd M. A longitudinal study of children of alcoholics: predicting young adult substance use disorders, anxiety, and depression. J Abnorm Psychol 108 (1999) 106-119
84. Hill S.Y., and Muka D. Childhood psychopathology in children from families of alcoholic female probands. J Am Acad Child Adolesc Psychiatry 35 (1996) 725-733
85. Merikangas K.R. Genetic epidemiologic studies of affective disorders in childhood and adolescence. Eur Arch Clin Neurosci 243 (1993) 121-130
86. Sher K.J., Walitzer K.S., Wood P.K., and Brent E.E. Characteristics of children of alcoholics: putative risk factors, substance use and abuse, and psychopathology. J Abnorm Psychol 100 (1991) 427-448
87. Merikangas K.R., Stevens D.E., Fenton B., et al. Comorbidity and familial aggregation of alcoholism and anxiety disorders. Psychol Med 28 (1998) 773-788
88. Merikangas K.R., Dierker L.C., and Szatmari P. Psychopathology among offspring of parents with substance abuse and/or anxiety: a high risk study. J Am Acad Child Adolesc Psychiatry 39 (1998) 711-720
89. Baron R.M., and Kenny D.A. The moderator-mediator variable distinction in social psychological research: conceptual, strategic, and statistical considerations. J Person Soc Psychol 51 (1986) 1173-1182
90. Parker G., Tupling H., and Brown L.B. A parental bonding instrument. Br J Med Psychol 52 (1979) 1-10
91. Olson D.H., Portner J., and Lavee Y. Family Adaptability and Cohesion Evaluation Scales FACES III. Family Social Science (1985), University of Minnesota, St. Paul MN
92. Olson D.H., Spenkle D.H., and Russell C.S. Complex model of martial and family systems. I: Cohesion and adaptability dimensions, family types and clinical applications. Fam Process 18 (1979) 3-78
93. Avenevoli S., and Merikangas K.R. Familial influences on adolescent smoking. Addiction 98 suppl 1 (2003) 1-20