Palmitoylation at Cys595 is essential for PECAM-1 localisation into membrane microdomains and for efficient PECAM-1-mediated cytoprotein

Thrombosis and Haemostasis

Volumn 96, Issue 6, 2006, Pages 756-766

  Sardjono, Caroline T ^a   Harbour, Stacey N ^a   Yip, Jana C ^a   Paddock, Cathy ^c   Tridandapani, Susheela ^b   Newman, Peter J ^c   Jackson, Denise E ^a  

^a AUSTIN RESEARCH INSTITUTE   (Australia)

^b OHIO STATE UNIVERSITY   (United States)

^c BLOOD RESEARCH INSTITUTE   (United States)

Author keywords

Adhesion receptors; GPVI; Lipid rafts; Platelet physiology; Signal transduction

Indexed keywords

ALANINE; AMINO ACID; CD31 ANTIGEN; CHOLESTEROL; COLLAGEN; CYSTEINE; GLYCOPROTEIN VI; IMMUNOGLOBULIN G; THIOESTER; THROMBIN; TYLOXAPOL; ETOPOSIDE; FC GAMMA RECEPTOR IIA; FC RECEPTOR; FIBRINOGEN RECEPTOR; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; LEUKOCYTE ANTIGEN; PALMITIC ACID; PLATELET MEMBRANE GLYCOPROTEIN VI;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL FRACTIONATION; CELL MEMBRANE; CELL NUCLEUS; CELL PROTECTION; CELL STIMULATION; CONTROLLED STUDY; CYTOPLASM; CYTOSKELETON; HUMAN; HUMAN CELL; MOUSE; MUTATIONAL ANALYSIS; NONHUMAN; PALMITOYLATION; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN TARGETING; SEPARATION TECHNIQUE; SIGNAL TRANSDUCTION; SOLUBILITY; SUCROSE DENSITY GRADIENT CENTRIFUGATION; THROMBOCYTE ACTIVATION; THROMBOCYTE MEMBRANE; ANIMAL; CELL LINE; CHEMISTRY; DRUG EFFECT; ENDOTHELIUM CELL; GENETIC TRANSFECTION; GENETICS; IN VITRO STUDY; METABOLISM; MICROFILAMENT; MUTATION; PROTEIN BINDING; PROTEIN PROCESSING; PROTEIN TERTIARY STRUCTURE; PROTEIN TRANSPORT; REPORTER GENE; THROMBOCYTE;

ANIMALS; ANTIGENS, CD; ANTIGENS, CD31; APOPTOSIS; BLOOD PLATELETS; CELL LINE; CHOLESTEROL; CYSTEINE; CYTOPLASM; ENDOTHELIAL CELLS; ETOPOSIDE; GENES, REPORTER; GREEN FLUORESCENT PROTEINS; HUMANS; MEMBRANE MICRODOMAINS; MICROFILAMENTS; MUTATION; PALMITIC ACID; PLATELET ACTIVATION; PLATELET MEMBRANE GLYCOPROTEINS; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; RECEPTORS, IGG; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 33845352343     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH06-08-0459     Document Type: Article

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