Pathological shear stress directly regulates platelet α IIbβ3 signaling

American Journal of Physiology - Cell Physiology

Volumn 291, Issue 6, 2006, Pages

  Feng, Shuju ^a   Lu, Xin ^a   Reséndiz, Julio C ^b   Kroll, Michael H ^a,c  

^a RICE UNIVERSITY   (United States)

^b WIHURI RESEARCH INSTITUTE   (Finland)

^c MICHAEL E DEBAKEY VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Integrin; Mechanoreceptor; Platelets; Shear stress; Signal transduction

Indexed keywords

ADAPTOR PROTEIN; ALPHA ACTININ; GLYCOPROTEIN IB; INTEGRIN; INTEGRIN ALPHA2B BETA3; MYOSIN HEAVY CHAIN; PROTEIN KINASE SYK; PROTEIN SH2; PROTEIN SLP 76; TYROSINE; VON WILLEBRAND FACTOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOSKELETON; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SHEAR STRESS; SRC HOMOLOGY DOMAIN; THROMBOCYTE; THROMBOCYTE AGGREGATION; THROMBOCYTE FUNCTION; VISCOMETER;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ACTININ; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BLOOD PLATELETS; CHO CELLS; CRICETINAE; CRICETULUS; CYTOSKELETON; FOCAL ADHESION KINASE 1; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MECHANOTRANSDUCTION, CELLULAR; PHOSPHOPROTEINS; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; PROTEIN BINDING; PROTEIN-TYROSINE KINASES; SHEAR STRENGTH; SIGNAL TRANSDUCTION; STRESS, MECHANICAL; VON WILLEBRAND FACTOR;

CRICETULUS GRISEUS;

EID: 33845332376     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00559.2005     Document Type: Article

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