Truncation of the cytoplasmic domain of β3 in a variant form of glanzmann thrombasthenia abrogates signaling through the integrin α(IIb)β3 complex

Journal of Clinical Investigation

Volumn 100, Issue 9, 1997, Pages 2393-2403

  Wang, Ronggang ^a,b   Shattil, Sanford J ^c   Ambruso, Daniel R ^d   Newman, Peter J ^a,b  

^a BLOOD RESEARCH INSTITUTE   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

^d UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

Glanzmann thrombasthenia; Inherited platelet defects; Integrin signal transduction; pp125(FAK)

Indexed keywords

FIBRINOGEN RECEPTOR; INTEGRIN; MESSENGER RNA;

ANIMAL CELL; ARTICLE; CASE REPORT; CHO CELL; CONTROLLED STUDY; GLANZMANN DISEASE; HEMOSTASIS; HUMAN; HUMAN CELL; MALE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; SCHOOL CHILD; SIGNAL TRANSDUCTION; THROMBOCYTE AGGREGATION;

EID: 0030664425     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119780     Document Type: Article

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