Synthesis and biological evaluation of analogues of cryptolepine, an alkaloid isolated from the suriname rainforest

Journal of Natural Products

Volumn 62, Issue 7, 1999, Pages 976-983

  Yang, Shu Wei ^a   Abdel Kader, Maged ^a   Malone, Stan ^b   Werkhoven, Marga C M ^c   Wisse, Jan H ^d   Bursuker, Isia ^e   Neddermann, Kim ^e   Fairchild, Craig ^e   Raventos Suarez, Carmen ^e   Menendez, Ana T ^e   Lane, Kate ^e   Kingston, David G I ^a  

^a VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

^b Conservation International Suriname ^*  (Suriname)

^c National Herbarium of Suriname   (Suriname)

^d Bedrijf Geneesmiddelen Voorziening Suriname   (Suriname)

^e BRISTOL MYERS SQUIBB   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 HYDROXYETHYLQUINDOLINE 11 CARBOXYLIC ACID; 2 METHYL 2 [11 (AMINOMETHYL)QUINDOLINE] 1,3 PROPANEDIOL; ANTINEOPLASTIC AGENT; CRYPTOLEPINE; CRYPTOLEPINE DERIVATIVE; PLANT EXTRACT; QUINDOLINE 11 CARBOXYLIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOASSAY; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CYTOTOXICITY; DRUG ISOLATION; DRUG POTENCY; DRUG SYNTHESIS; FOREST; HERBAL MEDICINE; IN VITRO STUDY; NONHUMAN; REACTION ANALYSIS; STRUCTURE ANALYSIS; SURINAME;

ALKALOIDS; ANTIFUNGAL AGENTS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL CYCLE; DNA DAMAGE; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; INDOLES; MICROBIAL SENSITIVITY TESTS; PLANTS, MEDICINAL; QUINOLINES; SACCHAROMYCES CEREVISIAE; SURINAME; TUMOR CELLS, CULTURED;

ANIMALIA; GENIPA AMERICANA; MAMMALIA; MICROPHILIS; MICROPHILIS GUYANENSIS;

EID: 0032769279     PISSN: 01633864     EISSN: None     Source Type: Journal    
DOI: 10.1021/np990035g     Document Type: Article

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