Fully automated continuous flow synthesis of 4,5-disubstituted oxazoles

Organic Letters

Volumn 8, Issue 23, 2006, Pages 5231-5234

  Baumann, Marcus ^a   Baxendale, Ian R ^a   Ley, Steven V ^a   Smith, Christoper D ^a   Tranmer, Geoffrey K ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 33845236565     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol061975c     Document Type: Article

References (39)

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36. PS-BEMP refers to 2-tert-butylimino-2-diethylamino-1,3-dimethylperhydro- 1,3,2-diazaphosphorine on polystyrene 2% DVB.
37. The observation of differences in kinetics could be a consequence of local concentration effects or polarity changes in the environment of the polymeric species.
38. Quadrapure BZA is a primary amine-functionalized resin with an effective loading of ∼5.5 mmol/g. Available from Reaxa Ltd. (Blackley, Manchester, U.K.).
39. A Vapourtec R-4 flow reactor heater is available from Vapourtec Ltd., Place farm, Ingham, Suffolk, IP31 1NQ, U.K. (www.vapourtec.com).