Genetic association studies of complex neurological diseases

Journal of Neurology, Neurosurgery and Psychiatry

Volumn 77, Issue 12, 2006, Pages 1302-1304

  Abou Sleiman, P M ^a   Hanna, M G ^a   Wood, N W ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DISEASE PREDISPOSITION; GENE REPLICATION; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC DISORDER; GENETIC SCREENING; GENOTYPE; HUMAN; INHERITANCE; NEUROLOGIC DISEASE; OUTCOME ASSESSMENT; PHENOTYPE; POPULATION GENETICS; POPULATION RESEARCH; PRIORITY JOURNAL; REVIEW;

CASE-CONTROL STUDIES; COHORT STUDIES; DEMOGRAPHY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; NERVOUS SYSTEM DISEASES; RESEARCH DESIGN; SAMPLE SIZE;

EID: 33845231345     PISSN: 00223050     EISSN: 1468330X     Source Type: Journal    
DOI: 10.1136/jnnp.2005.082024     Document Type: Review

References (16)

1. Risch N, Merikangas K. The future of genetic studies of complex human diseases. Science 1996;273:1516-17.
2. Ioannidis JP, Trikalinos TA, Ntzani EE, et al. Genetic associations in large versus small studies: an empirical assessment. Lancet 2003;361:567-71.
3. Lohmueller KE, Pearce CL, Pike M, et al. Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease. Nat Genet 2003;33:177-82.
4. Hirschhorn JN, Daly MJ. Genome-wide association studies for common diseases and complex traits. Nat Rev Genet 2005;6:95-108.
5. Pritchard JK, Rosenberg NA. Use of unlinked genetic markers to detect population stratification in association studies. Am J Hum Genet 1999;65:220-8.
6. Devlin B, Roeder K. Genomic control for association studies. Biometrics 1999;55:997-1004.
7. Freedman ML, Reich D, Penney KL, et al. Assessing the impact of population stratification on genetic association studies. Nat Genet 2004;36:388-93.
8. Ardlie KG, Lunetta KL, Seielstad M. Testing for population subdivision and association in four case-control studies. Am J Hum Genet 2002;71:304-11.
9. Cardon LR, Palmer LJ. Population stratification and spurious allelic association. Lancet 2003;361:598-604.
10. Schaid DJ, Sommer SS. Genotype relative risks: methods for design and analysis of candidate-gene association studies. Am J Hum Genet 1993;53:1114-26.
11. Weinberg CR. Studying parents and grandparents to assess genetic contributions to early-onset disease. Am J Hum Genet 2003;72:438-47.
12. Purcell S, Cherny SS, Sham PC. Genetic Power Calculator: design of linkage and association genetic mapping studies of complex traits. Bioinformatics 2003;19:149-50.
13. Goldstein DB, Ahmadi KR, Weale ME, et al. Genome scans and candidate gene approaches in the study of common diseases and variable drug responses. Trends Genet 2003;19:615-22.
14. Wall JD, Pritchard JK. Haplotype blocks and linkage disequilibrium in the human genome. Nat Rev Genet 2003;4:587-97.
15. Gordon D, Finch SJ, Nothnagel M, et al. Power and sample size calculations for case-control genetic association tests when errors are present: application to single nucleotide polymorphisms. Hum Hered 2002;54:22-33.
16. Cordell HJ, Clayton DG. Genetic association studies. Lancet 2005;366:1121-31.