Role of T lymphocyte replicative senescence in vaccine efficacy

Vaccine

Volumn 25, Issue 4, 2007, Pages 599-604

  Effros, Rita B ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Aging; CD28; Humans; Replicative senescence; T lymphocytes; Vaccines

Indexed keywords

CD28 ANTIGEN; CHICKENPOX VACCINE; CHOLERA TOXIN; CPG OLIGODEOXYNUCLEOTIDE; CYTOMEGALOVIRUS VACCINE; DIPHTHERIA PERTUSSIS TETANUS VACCINE; INACTIVATED VACCINE; INFLUENZA VACCINE; LIVE VACCINE; TRIPLE VACCINE;

ADJUVANT THERAPY; ANTIBODY TITER; AVIAN INFLUENZA; CD8+ T LYMPHOCYTE; CELL AGING; CELL CYCLE ARREST; CELL DIVISION; CHICKENPOX; CPG ISLAND; CYTOMEGALOVIRUS INFECTION; DIPHTHERIA; DRUG EFFICACY; DRUG POTENTIATION; DRUG RESPONSE; EPIDEMIC; GERIATRIC PATIENT; HERPES ZOSTER; HIGH RISK POPULATION; HUMAN; IMMUNOMODULATION; IMMUNOREACTIVITY; INFECTION PREVENTION; INFECTION RISK; INFLUENZA; INFLUENZA VACCINATION; LYMPHOCYTE PROLIFERATION; MUCOSAL IMMUNITY; PERTUSSIS; PRIORITY JOURNAL; PROTEIN MOTIF; REVIEW; SENESCENCE; SUPPRESSOR CELL; T LYMPHOCYTE; TETANUS; TH1 CELL; TH2 CELL; VACCINATION; VARICELLA ZOSTER VIRUS;

AGING; ANIMALS; CELL PROLIFERATION; T-LYMPHOCYTES; VACCINES;

EID: 33845215290     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2006.08.032     Document Type: Review

References (57)

1. McElhaney J.E., Xie D., Hager W.D., et al. T cell responses are better correlates of vaccine protection in the elderly. J Immunol 176 10 (2006) 6333-6339
2. Vandepapeliere P. Therapeutic vaccination against chronic viral infections. Lancet Infect Dis 2 6 (2002) 353-367
3. Letvin N.L. Strategies for an HIV vaccine. J Clin Invest 110 1 (2002) 15-20
4. Pasetti M.F., Salerno-Goncalves R., and Sztein M.B. Salmonella enterica serovar typhi live vector vaccines delivered intranasally elicit regional and systemic specific CD8(+) major histocompatibility class i-restricted cytotoxic T lymphocytes. Infect Immun 70 8 (2002) 4009-4018
5. Rhee E.G., Mendez S., Shah J.A., et al. Vaccination with heat-killed leishmania antigen or recombinant leishmanial protein and CpG oligodeoxynucleotides induces long-term memory CD4+ and CD8+ T cell responses and protection against leishmania major infection. J Exp Med 195 12 (2002) 1565-1573
6. Ennis F.A., Cruz J., Demkowicz Jr. W.E., Rothman A.L., and McClain D.J. Primary induction of human CD8+ cytotoxic T lymphocytes and interferon-gamma-producing T cells after smallpox vaccination. J Infect Dis 185 11 (2002) 1657-1659
7. Webster R.G. Immunity to influenza in the elderly. Vaccine 18 16 (2000) 1686-1689
8. Muszkat M., Friedman G., Schein M.H., et al. Local SIgA response following administration of a novel intranasal inactivated influenza virus vaccine in community residing elderly. Vaccine 18 16 (2000) 1696-1699
9. Ruh M.F., Bi Y., Cox L., Berk D., Howlett A.C., and Bellone C.J. Effect of environmental estrogens on IL-1beta promoter activity in a macrophage cell line. Endocrine 9 2 (1998) 207-211
10. Asanuma H., Hirokawa K., Uchiyama M., et al. Immune responses and protection in different strains of aged mice immunized intranasally with an adjuvant-combined influenza vaccine. Vaccine 19 28-29 (2001) 3981-3989
11. Manning B.M., Enioutina E.Y., Visic D.M., Knudson A.D., and Daynes R.A. CpG DNA functions as an effective adjuvant for the induction of immune responses in aged mice. Exp Gerontol 37 1 (2001) 107-126
12. Castle S., Uyemura K., Wong W., Modlin R., and Effros R.B. Evidence of enhanced type 2 immune response and impaired upregulation of a type 1 response in frail elderly nursing home residents. Mech Ageing Dev 94 (1997) 7-16
13. Stepanova L., Naykhin A., Kolmskog C., et al. The humoral response to live and inactivated influenza vaccines administered alone and in combination to young adults and elderly. J Clin Virol 24 3 (2002) 193-201
14. Fujihashi K., Koga T., and McGhee J.R. Mucosal vaccination and immune responses in the elderly. Vaccine 18 16 (2000) 1675-1680
15. Verreault R., Laurin D., Lindsay J., and De Serres G. Past exposure to vaccines and subsequent risk of Alzheimer's disease. CMAJ 165 11 (2001) 1495-1498
16. Panossian L., Porter V.R., Valenzuela H.F., et al. Telomere shortening in T cells correlates with Alzheimer's disease status. Neurobiol Aging (2002)
17. Monsonego A., Zota V., Karni A., et al. Increased T cell reactivity to amyloid beta protein in older humans and patients with Alzheimer disease. J Clin Invest 112 3 (2003) 415-422
18. Goronzy J.J., Fulbright J.W., Crowson C.S., Poland G.A., O'Fallon W.M., and Weyand C.M. Value of immunological markers in predicting responsiveness to influenza vaccination in elderly individuals. J Virol 75 24 (2001) 12182-12187
19. Saurwein-Teissl M., Lung T.L., Marx F., et al. Lack of antibody production following immunization in old age: association with CD8(+)CD28(-) T cell clonal expansions and an imbalance in the production of Th1 and Th2 cytokines. J Immunol 168 11 (2002) 5893-5899
20. Trzonkowski P., Mysliwska J., Szmit E., et al. Association between cytomegalovirus infection, enhanced proinflammatory response and low level of anti-hemagglutinins during the anti-influenza vaccination-an impact of immunosenescence. Vaccine 21 25-26 (2003) 3826-3836
21. Ouyang Q., Wagner W.M., Wikby A., Remarque E., and Pawelec G. Compromised interferon gamma (IFN-gamma) production in the elderly to both acute and latent viral antigen stimulation: contribution to the immune risk phenotype?. Eur Cytokine Network 13 4 (2002) 392-394
22. June C.H., Bluestone J.A., Nadler L., and Thompson C.B. The B7 and CD28 receptor families. Immunol Today 15 (1994) 321-331
23. Reiter R., and Pfeffer K. Impaired germinal centre formation and humoral immune response in the absence of CD28 and interleukin-4. Immunology 106 2 (2002) 222-228
24. Shimizu Y., Van Seventer G., Ennis E., Newman W., Horgan K., and Shaw S. Crosslinking of the T cell-specific accessory moleculesCD7 and CD28 modulates T cell adhesion. J Exp Med 175 (1992) 577-582
25. Boucher N., Defeu-Duchesne T., Vicaut E., Farge D., Effros R.B., and Schachter F. CD28 expression in T cell aging and human longevity. Exp Geronol 33 (1998) 267-282
26. Posnett D.N., Sinha R., Kabak S., and Russo C. Clonal populations of T cells in normal elderly humans: the T cell equivalent to "benign monoclonal gammopathy". J Exp Med 179 (1994) 609-618
27. Azuma M., Phillips J.H., and Lanier L.L. CD28- T lymphocytes: antigenic and functional properties. J Immunol 150 (1993) 1147-1159
28. Effros R.B., Allsopp R., Chiu C.P., et al. Shortened telomeres in the expanded CD28-CD8+ subset in HIV disease implicate replicative senescence in HIV pathogenesis. AIDS/Fast Track 10 (1996) F17-F22
29. Harley CB. Telomeres and aging: Fact, fancy, and the future. J NIH Res 7:64-8.
30. Posnett D.N., Edinger J.W., Manavalan J.S., Irwin C., and Marodon G. Differentiation of human CD8 T cells: implications for in vivo persistence of CD8+ CD28- cytotoxic effector clones. Int Immunol 11 2 (1999) 229-241
31. Smith J.R., and Pereira-Smith O.M. Replicative senescence: implications for in vivo aging and tumor suppression. Science 273 (1996) 63-66
32. Campisi J., Kim S.H., Lim C.S., and Rubio M. Cellular senescence, cancer and aging: the telomere connection. Exp Gerontol 36 10 (2001) 1619-1637
33. Krtolica A., Parrinello S., Lockett S., Desprez P.Y., and Campisi J. Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging. Proc Natl Acad Sci USA 98 21 (2001) 12072-12077
34. Effros R.B. Replicative senescence in the immune system: impact of the Hayflick limit on T cell function in the elderly. Am J Hum Gen 62 (1998) 1003-1007
35. Weng N.P., Hathcock K.S., and Hodes R.J. Regulation of telomere length and telomerase in T and B cells: a mechanism for maintaining replicative potential. Immunity 9 2 (1998) 151-157
36. Bodnar A.G., Kim N.W., Effros R.B., and Chiu C.P. Mechanism of telomerase induction during T cell activation. Exp Cell Res 228 (1996) 58-64
37. Weng N.P., Levine B.L., June C.H., and Hodes R.J. Regulation of telomerase RNA template expression in human T lymphocyte development and activation. J Immunol 158 7 (1997) 3215-3220
38. Valenzuela H.F., and Effros R.B. Divergent telomerase and CD28 expression patterns in human CD4 and CD8 T cells following repeated encounters with the same antigenic stimulus. Clin Immunol 105 2 (2002) 117-125
39. Morley J.K., Batliwalla F.M., Hingorani R., and Gregersen P.K. Oligoclonal CD8+ T cells are preferentially expanded in the CD57+ subset. J Immunol 154 (1995) 6182-6190
40. Maini M.K., Casorati G., Dellabona P., Wack A., and Beverley P.C. T-cell clonality in immune responses. Immunol Today 20 6 (1999) 262-266
41. Effros R.B., Dagarag M.D., Spaulding C.C., and Man J. The role of CD8 T cell replicative senescence in human aging. Immunol Rev 205 (2005) 147-157
42. Cortesini R., LeMaoult J., Ciubotariu R., and Cortesini N.S. CD8+CD28- T suppressor cells and the induction of antigen-specific, antigen-presenting cells-mediated suppression of Th reactivity. Immunol Rev 182 (2001) 201-206
43. Schirmer M., Goldberger C., Wurzner R., et al. Circulating cytotoxic CD8(+) CD28(-) T cells in ankylosing spondylitis. Arthritis Res 4 1 (2002) 71-76
44. Pilch H., Hoehn H., Schmidt M., et al. CD8+CD45RA+CD27-CD28-T-cell subset in PBL of cervical cancer patients representing CD8+T-cells being able to recognize cervical cancer associated antigens provided by HPV 16 E7. Zentralbl Gynakol 124 8-9 (2002) 406-412
45. Jonasson L., Tompa A., and Wikby A. Expansion of peripheral CD8+ T cells in patients with coronary artery disease: relation to cytomegalovirus infection. J Intern Med 254 5 (2003) 472-478
46. Tsukishiro T., Donnenberg A.D., and Whiteside T.L. Rapid turnover of the CD8(+)CD28(-) T-cell subset of effector cells in the circulation of patients with head and neck cancer. Cancer Immunol Immunother 52 10 (2003) 599-607
47. Trannoy E., Berger R., Hollander G., et al. Vaccination of immunocompetent elderly subjects with a live attenuated Oka strain of varicella zoster virus: a randomized, controlled, dose-response trial. Vaccine 18 16 (2000) 1700-1706
48. Oxman M.N., Levin M.J., Johnson G.R., et al. A vaccine to prevent herpes zoster and postherpetic neuralgia in older adults. N Engl J Med 352 22 (2005) 2271-2284
49. Falsey A.R., Walsh E.E., Looney R.J., et al. Comparison of respiratory syncytial virus humoral immunity and response to infection in young and elderly adults. J Med Virol 59 2 (1999) 221-226
50. Looney R.J., Falsey A.R., Walsh E., and Campbell D. Effect of aging on cytokine production in response to respiratory syncytial virus infection. J Infect Dis 185 5 (2002) 682-685
51. Goodkin K., Wilkie F.L., Concha M., et al. Aging and neuro-AIDS conditions and the changing spectrum of HIV-1-associated morbidity and mortality. J Clin Epidemiol 54 Suppl 1 (2001) S35-S43
52. Appay V., and Rowland-Jones S. Premature ageing of the immune system: the cause of AIDS?. Trends Immunol 23 12 (2002) 580-585
53. Fagnoni F.F., Vescovini R., Passeri G., et al. Shortage of circulating naive CD8(+) T cells provides new insights on immunodeficiency in aging. Blood 95 9 (2000) 2860-2868
54. Nilsson B.O., Ernerudh J., Johansson B., et al. Morbidity does not influence the T-cell immune risk phenotype in the elderly: findings in the Swedish NONA Immune Study using sample selection protocols. Mech Ageing Dev 124 4 (2003) 469-476
55. Wikby A., Johansson B., Olsson J., Lofgren S., Nilsson B.O., and Ferguson F. Expansions of peripheral blood CD8 T-lymphocyte subpopulations and an association with cytomegalovirus seropositivity in the elderly: the Swedish NONA Immune Study. Exp Gerontol 37 2-3 (2002) 445-453
56. Pawelec G., Akbar A., Caruso C., Effros R., Grubeck-Loebenstein B., and Wikby A. Is immunosenescence infectious?. Trends Immunol 25 8 (2004) 406-410
57. Dagarag M.D., Evazyan T., Rao N., and Effros R.B. Genetic manipulation of telomerase in HIV-specific CD8+ T cells:enhanced anti-viral functions accompany the increased proliferative potential and telomere length stabilization. J Immunol 173 Nov 15 (2004) 6303-6311