T-type Ca2+ channels mediate propagation of odor-induced Ca2+ transients in rat olfactory receptor neurons

Neuroscience

Volumn 144, Issue 2, 2007, Pages 702-713

  Gautam, S H ^a   Otsuguro, K I ^a   Ito, S ^a   Saito, T ^b   Habara, Y ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF AGROBIOLOGICAL SCIENCES   (Japan)

Author keywords

Ca2+ dynamics; LVA Ca2+ channels; mibefradil; Ni2+; signal transduction

Indexed keywords

CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL T TYPE; CALCIUM ION; FORSKOLIN; GLUTAMIC ACID DERIVATIVE; ISOBUTYLMETHYLXANTHINE; MIBEFRADIL; NICKEL; POTASSIUM ION; PROTEIN SUBUNIT; SODIUM ION; ANILINE DERIVATIVE; CALCIUM; FLUO 4; PHOSPHODIESTERASE INHIBITOR; POTASSIUM CHLORIDE; XANTHENE DERIVATIVE;

ANIMAL CELL; ARTICLE; CALCIUM CURRENT; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DENDRITE; MALE; NERVE CELL; NONHUMAN; ODOR; OLFACTORY DISCRIMINATION; OLFACTORY RECEPTOR; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; ANIMAL; CONFOCAL MICROSCOPY; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; DRUG INTERACTION; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; METABOLISM; METHODOLOGY; OLFACTORY BULB; PHYSIOLOGY; TIME; WISTAR RAT;

1-METHYL-3-ISOBUTYLXANTHINE; ANILINE COMPOUNDS; ANIMALS; CALCIUM; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, T-TYPE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; FORSKOLIN; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; MALE; MIBEFRADIL; MICROSCOPY, CONFOCAL; NICKEL; ODORS; OLFACTORY BULB; OLFACTORY RECEPTOR NEURONS; PHOSPHODIESTERASE INHIBITORS; POTASSIUM CHLORIDE; RATS; RATS, WISTAR; TIME FACTORS; XANTHENES;

EID: 33845192105     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2006.10.012     Document Type: Article

References (44)

1. Clozel J.P., Ertel E.A., and Ertel S.I. Discovery and main pharmacological properties of mibefradil (Ro 40-5967), the first selective T-type calcium channel blocker. J Hypertens 15 (1997) S17-S25
2. 2+ channel gene family. Circ Res 83 (1998) 103-109
3. Firestein S., Picco C., and Menini A. The relation between stimulus and response in olfactory receptor cells of the tiger salamander. J Physiol 468 (1993) 1-10
4. 2+ dynamics in rat olfactory receptor neurons. Neurosci Res 55 (2006) 410-420
5. Gold G.H. Controversial issues in vertebrate olfactory transduction. Annu Rev Physiol 61 (1999) 857-871
6. Hosaka Y., Yanase H., and Iwanaga T. Morphological analysis of olfactory receptor cells using whole-mount preparations of the rat nasal mucosa. J Vet Med Sci 60 (1998) 897-904
7. Huguenard J.R. Low-threshold calcium currents in central nervous system neurons. Annu Rev Physiol 58 (1996) 329-348
8. 3-gated channels and their occurrence relative to CNG channels in the soma and dendritic knob of rat olfactory receptor neurons. J Membr Biol 181 (2001) 91-105
9. 2+ channel lowers the threshold of spike generation in the newt olfactory receptor cell. J Gen Physiol 108 (1996) 525-535
10. 2+ currents of odour sensitivity in olfactory receptor cells. J Neurosci 21 (2001) RC144
11. Kurahashi T. Activation by odorants of cation-selective conductance in the olfactory receptor cell isolated from the newt. J Physiol 419 (1989) 177-192
12. Kurahashi T., and Yau K.W. Coexistence of cationic and chloride components in odorant-induced current of vertebrate olfactory receptor cells. Nature 363 (1993) 71-74
13. Leinders-Zufall T., Greer C.A., Shepherd G.M., and Zufall F. Imaging odour-induced calcium transients in single olfactory cilia: specificity of activation and role in transduction. J Neurosci 18 (1998) 5630-5639
14. Leinders-Zufall T., Rand M.N., Shepherd G.M., Greer C.A., and Zufall F. Calcium entry through cyclic nucleotide-gated channels in individual cilia of olfactory receptor cells: spatiotemporal dynamics. J Neurosci 17 (1997) 4136-4148
15. Lowe G., and Gold G.H. Nonlinear amplification by calcium-dependent chloride channels in olfactory receptor-cells. Nature 366 (1993) 283-286
16. Lynch J.W., and Barry P.H. Action potentials initiated by single channels opening in a small neuron (rat olfactory receptor). Biophys J 55 (1989) 755-768
17. Ma M., Chen W.R., and Shepherd G.M. Electrophysiological characterization of rat and mouse olfactory receptor neurons from an intact epithelial preparation. J Neurosci Methods 92 (1999) 31-40
18. Martin R.L., Lee J., Cribbs L.L., Perez-Reyes E., and Hank D.A. Mibefradil block of cloned T-type calcium channels. J Pharmacol Exp Ther 295 (2000) 302-308
19. Matthews H.R., and Reisert J. Calcium, the two-faced messenger of olfactory transduction and adaptation. Curr Opin Neurobiol 13 (2003) 469-475
20. Menco B.P.M. Ultrastructural aspects of olfactory signaling. Chem Senses 22 (1997) 295-311
21. olfα and type III adenylyl cyclase. Neuron 8 (1992) 441-453
22. Menini A. Calcium signalling and regulation in olfactory neurons. Curr Opin Neurobiol 9 (1999) 419-426
23. v3.2 calcium channels. Mol Pharmacol 61 (2002) 682-694
24. 2+ channels by Ro 40-5967. Circ Res 75 (1994) 144-148
25. Narusuye K., Kawai F., and Miyachi E. Spike encoding of olfactory receptor cells. Neurosci Res 46 (2003) 407-413
26. Okada Y., Miyamoto T., and Toda K. Dopamine modulates a voltage-gated calcium channel in rat olfactory receptor neurons. Brain Res 968 (2003) 248-255
27. 2+ signals in rat olfactory neurons. J Pharmacol Sci 97 (2005) 510-518
28. 2+ channels mediate neurotransmitter release in retinal bipolar cells. Neuron 32 (2001) 89-98
29. Perez-Reyes E. Molecular physiology of low-voltage-activated T-type calcium channels. Physiol Rev 83 (2003) 117-161
30. Perez-Reyes E. Three for T: molecular analysis of the low voltage-activated calcium channel family. Cell Mol Life Sci 56 (1999) 660-669
31. Qu W., Moorhouse A.J., Rajendra S., and Barry P.H. Very negative potential for half-inactivation of, and effects of anions on, voltage-dependent sodium currents in acutely isolated rat olfactory receptor neurons. J Membr Biol 175 (2000) 123-138
32. + currents in rat olfactory receptor neurons. Pflugers Arch 420 (1992) 342-346
33. Reisert J., Bauer P.J., Yau K.W., and Frings S. The Ca-activated Cl channel and its control in rat olfactory receptor neurons. J Gen Physiol 122 (2003) 349-363
34. 2+ gradients in rat olfactory neurons. J Gen Physiol 102 (1993) 907-924
35. Reuter D., Zierold K., Schröder W.H., and Frings S. A depolarizing chloride current contributes to chemoelectrical transduction in olfactory sensory neurons in situ. J Neurosci 18 (1998) 6623-6630
36. Ronnett G.V., and Moon C. G proteins and olfactory signal transduction. Annu Rev Physiol 64 (2002) 189-222
37. Schild D., Jung A., and Schultens H.A. Localization of calcium entry through calcium channels in olfactory receptor neurons using a laser scanning microscope and the calcium indicator dyes Fluo-3 and Fura-Red. Cell Calcium 15 (1994) 341-348
38. Schild D., and Restrepo D. Transduction mechanisms in vertebrate olfactory receptor cells. Physiol Rev 78 (1998) 429-466
39. 2+ channels. Biochem Pharmacol 69 (2005) 841-854
40. + concentration. Mol Cell Endocrinol 217 (2004) 23-26
41. Strege P.R., Bernard C.E., Ou Y., Gibbons S.J., and Farrugia G. Effect of mibefradil on sodium and calcium currents. Am J Physiol Gastrointest Liver Physiol 289 (2005) 249-253
42. Troiter D. A patch-clamp analysis of membrane currents in salamander olfactory receptor cells. Pflugers Arch 407 (1986) 589-595
43. Trombley P.Q., and Westbrook G.L. Voltage-gated currents in identified rat olfactory receptor neurons. J Neurosci 11 (1991) 435-444
44. Yamaguchi K., Habara Y., Warashina A., and Kanno T. Effects of corticosteroids on cytosolic free calcium concentration of rat adrenal zona glomerulosa cells. Biol Signals 2 (1993) 352-358