-
2
-
-
0027432424
-
Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: The role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses
-
Arcaro A, Wymann MP. 1993. Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: The role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses. Biochem J 296:297-301.
-
(1993)
Biochem J
, vol.296
, pp. 297-301
-
-
Arcaro, A.1
Wymann, M.P.2
-
3
-
-
0034647674
-
Translocation of Akt/PKB to the nucleus of osteoblast-like MC3T3-E1 cells exposed to proliferative growth factors
-
Borgatti P, Martelli AM, Bellacosa A, Casto R, Massari L, Capitani S, Neri LM. 2000. Translocation of Akt/PKB to the nucleus of osteoblast-like MC3T3-E1 cells exposed to proliferative growth factors. FEBS Lett 477:27-32.
-
(2000)
FEBS Lett
, vol.477
, pp. 27-32
-
-
Borgatti, P.1
Martelli, A.M.2
Bellacosa, A.3
Casto, R.4
Massari, L.5
Capitani, S.6
Neri, L.M.7
-
5
-
-
0037205048
-
The phosphoinositide 3-kinase pathway
-
Cantley LC. 2002. The phosphoinositide 3-kinase pathway. Science 296:1655-1657.
-
(2002)
Science
, vol.296
, pp. 1655-1657
-
-
Cantley, L.C.1
-
6
-
-
0032881288
-
AKT/PKB and other D3 phosphoinositide-regulated kinases: Kinase activation by phosphoinositide-dependent phosphorylation
-
Chan TO, Rittenhouse SE, Tsichlis PN, 1999. AKT/PKB and other D3 phosphoinositide-regulated kinases: Kinase activation by phosphoinositide- dependent phosphorylation. Annu Rev Biochem 68:965-1014.
-
(1999)
Annu Rev Biochem
, vol.68
, pp. 965-1014
-
-
Chan, T.O.1
Rittenhouse, S.E.2
Tsichlis, P.N.3
-
7
-
-
0035050958
-
The cell survival signal Akt is differentially activated by PDGF-BB, EGF, and FGF-2 in osteoblastic cells
-
Chaudhary LR, Hruska KA. 2001. The cell survival signal Akt is differentially activated by PDGF-BB, EGF, and FGF-2 in osteoblastic cells. J Cell Biochem 81:304-311.
-
(2001)
J Cell Biochem
, vol.81
, pp. 304-311
-
-
Chaudhary, L.R.1
Hruska, K.A.2
-
8
-
-
0032189381
-
Protein kinase B (c-Akt): A multifunctional mediator of phosphatidylinositol 3-kinase activation
-
Coffer PJ, Jin J, Woodgett JR. 1998. Protein kinase B (c-Akt): A multifunctional mediator of phosphatidylinositol 3-kinase activation. Biochem J 335:1-13.
-
(1998)
Biochem J
, vol.335
, pp. 1-13
-
-
Coffer, P.J.1
Jin, J.2
Woodgett, J.R.3
-
9
-
-
0029587224
-
Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
-
Cross DA, Alessi DR, Cohen P, Andjelkovich M, Hemmings BA. 1995. Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B. Nature 378:785-789.
-
(1995)
Nature
, vol.378
, pp. 785-789
-
-
Cross, D.A.1
Alessi, D.R.2
Cohen, P.3
Andjelkovich, M.4
Hemmings, B.A.5
-
10
-
-
0037432141
-
Calcium regulates the PI3K-Akt pathway in stretched osteoblasts
-
Danciu TE, Adam RM, Naruse K, Freeman MR, Hauschka PV. 2003. Calcium regulates the PI3K-Akt pathway in stretched osteoblasts. FEBS Lett 536:193-197.
-
(2003)
FEBS Lett
, vol.536
, pp. 193-197
-
-
Danciu, T.E.1
Adam, R.M.2
Naruse, K.3
Freeman, M.R.4
Hauschka, P.V.5
-
11
-
-
0033525763
-
Platelet-derived growth factor induces interleukin-6 transcription in osteoblasts through the activator protein-1 complex and activating transcription factor-2
-
Franchimont N, Durant D, Rydziel S, Canalis E. 1999. Platelet-derived growth factor induces interleukin-6 transcription in osteoblasts through the activator protein-1 complex and activating transcription factor-2. J Biol Chem 274:6783-6789.
-
(1999)
J Biol Chem
, vol.274
, pp. 6783-6789
-
-
Franchimont, N.1
Durant, D.2
Rydziel, S.3
Canalis, E.4
-
12
-
-
0032875460
-
Mechanism of action and in vivo role of platelet-derived growth factor
-
Heldin CH, Westermark B. 1999. Mechanism of action and in vivo role of platelet-derived growth factor. Physiol Rev 79:1283-1316.
-
(1999)
Physiol Rev
, vol.79
, pp. 1283-1316
-
-
Heldin, C.H.1
Westermark, B.2
-
13
-
-
0022655932
-
A human osteosarcoma cell line secretes a growth factor structurally related to a homodimer of PDGF A-chains
-
Heldin CH, Johnsson A, Wennergren S, Wernstedt C, Betsholtz C, Westermark B. 1986. A human osteosarcoma cell line secretes a growth factor structurally related to a homodimer of PDGF A-chains. Nature 319:511-514.
-
(1986)
Nature
, vol.319
, pp. 511-514
-
-
Heldin, C.H.1
Johnsson, A.2
Wennergren, S.3
Wernstedt, C.4
Betsholtz, C.5
Westermark, B.6
-
14
-
-
0037085234
-
New members of the platelet-derived growth factor family of mitogens
-
Heldin CH, Eriksson U, Ostman A. 2002. New members of the platelet-derived growth factor family of mitogens. Arch Biochem Biophys 398:284-290.
-
(2002)
Arch Biochem Biophys
, vol.398
, pp. 284-290
-
-
Heldin, C.H.1
Eriksson, U.2
Ostman, A.3
-
16
-
-
0033790375
-
gp130 Cytokine family and bone cells
-
Heymann D, Rousselle AV. 2000. gp130 Cytokine family and bone cells. Cytokine 12:1455-1468.
-
(2000)
Cytokine
, vol.12
, pp. 1455-1468
-
-
Heymann, D.1
Rousselle, A.V.2
-
17
-
-
0034632791
-
3-(Hydroxymethyl)-bearing phosphatidylinositol ether lipid analogues and carbonate surrogates block PI3-K, Akt, and cancer cell growth
-
Hu Y, Qiao L, Wang S, Rong SB, Meuillet EJ, Berggren M, Gallegos A, Powis G, Kozikowski AP. 2000. 3-(Hydroxymethyl)-bearing phosphatidylinositol ether lipid analogues and carbonate surrogates block PI3-K, Akt, and cancer cell growth. J Med Chem 43:3045-3051.
-
(2000)
J Med Chem
, vol.43
, pp. 3045-3051
-
-
Hu, Y.1
Qiao, L.2
Wang, S.3
Rong, S.B.4
Meuillet, E.J.5
Berggren, M.6
Gallegos, A.7
Powis, G.8
Kozikowski, A.P.9
-
18
-
-
0025259989
-
IL-6 is produced by osteoblasts and induces bone resorption
-
Ishimi Y, Miyaura C, Jin CH, Akatsu T, Abe E, Nakamura Y, Yamaguchi A, Yoshiki S, Matsuda T, Hirano T. 1990. IL-6 is produced by osteoblasts and induces bone resorption. J Immunol 145:3297-3303.
-
(1990)
J Immunol
, vol.145
, pp. 3297-3303
-
-
Ishimi, Y.1
Miyaura, C.2
Jin, C.H.3
Akatsu, T.4
Abe, E.5
Nakamura, Y.6
Yamaguchi, A.7
Yoshiki, S.8
Matsuda, T.9
Hirano, T.10
-
19
-
-
16544387699
-
Nongenomic androgen activation of phosphatidylinositol 3-kinase/Akt signaling pathway in MC3T3-E1 osteoblasts
-
Kang HY, Cho CL, Huang KL, Wang JC, Hu YC, Lin HK, Chang C, Huang KE. 2004. Nongenomic androgen activation of phosphatidylinositol 3-kinase/Akt signaling pathway in MC3T3-E1 osteoblasts. J Bone Miner Res 19, 1181-1190.
-
(2004)
J Bone Miner Res
, vol.19
, pp. 1181-1190
-
-
Kang, H.Y.1
Cho, C.L.2
Huang, K.L.3
Wang, J.C.4
Hu, Y.C.5
Lin, H.K.6
Chang, C.7
Huang, K.E.8
-
20
-
-
0030058621
-
Modulation of the stress-induced synthesis of hsp27 and alpha B-crystallin by cyclic AMP in C6 rat glioma cells
-
Kato K, Ito H, Hasegawa K, Inaguma Y, Kozawa O, Asano T. 1996. Modulation of the stress-induced synthesis of hsp27 and alpha B-crystallin by cyclic AMP in C6 rat glioma cells. J Neurochem 66:946-950.
-
(1996)
J Neurochem
, vol.66
, pp. 946-950
-
-
Kato, K.1
Ito, H.2
Hasegawa, K.3
Inaguma, Y.4
Kozawa, O.5
Asano, T.6
-
21
-
-
0026541952
-
Cross-talk regulation between cyclic AMP production and phosphoinositide hydrolysis induced by prostaglandin E2 in osteoblast-like cells
-
Kozawa O, Tokuda H, Miwa M, Kotoyori J, Oiso Y. 1992. Cross-talk regulation between cyclic AMP production and phosphoinositide hydrolysis induced by prostaglandin E2 in osteoblast-like cells. Exp Cell Res 198:130-134.
-
(1992)
Exp Cell Res
, vol.198
, pp. 130-134
-
-
Kozawa, O.1
Tokuda, H.2
Miwa, M.3
Kotoyori, J.4
Oiso, Y.5
-
22
-
-
0029083616
-
Effect of platelet-derived growth factor on phosphatidylcholine- hydrolyzing phospholipase D in osteoblast-like cells
-
Kozawa O, Suzuki A, Watanabe Y, Shinoda J, Oiso Y. 1995. Effect of platelet-derived growth factor on phosphatidylcholine-hydrolyzing phospholipase D in osteoblast-like cells. Endocrinology 136:4473-4478.
-
(1995)
Endocrinology
, vol.136
, pp. 4473-4478
-
-
Kozawa, O.1
Suzuki, A.2
Watanabe, Y.3
Shinoda, J.4
Oiso, Y.5
-
23
-
-
1642432081
-
IL-6, RANKL, TNF-alpha/IL-1: Interrelations in bone resorption pathophysiology
-
Kwan Tat S, Padrines M, Theoleyre S, Heymann D, Fortun Y. 2004. IL-6, RANKL, TNF-alpha/IL-1: Interrelations in bone resorption pathophysiology. Cytokine Growth Factor Rev 15:49-60.
-
(2004)
Cytokine Growth Factor Rev
, vol.15
, pp. 49-60
-
-
Kwan Tat, S.1
Padrines, M.2
Theoleyre, S.3
Heymann, D.4
Fortun, Y.5
-
24
-
-
0014949207
-
Cleavage of structural proteins during the assembly of the head of bacteriophage T4
-
Laemmli UK. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685.
-
(1970)
Nature
, vol.227
, pp. 680-685
-
-
Laemmli, U.K.1
-
25
-
-
0026070184
-
The modulation of the expression of IL-6 and its receptor in human osteoblasts in vitro
-
Littlewood AJ, Russell J, Harvey GR, Hughes DE, Russell RG, Gowen M. 1991. The modulation of the expression of IL-6 and its receptor in human osteoblasts in vitro. Endocrinology 129:1513-1520.
-
(1991)
Endocrinology
, vol.129
, pp. 1513-1520
-
-
Littlewood, A.J.1
Russell, J.2
Harvey, G.R.3
Hughes, D.E.4
Russell, R.G.5
Gowen, M.6
-
26
-
-
0022969659
-
Cells of bone: Proliferation, differentiation, and hormonal regulation
-
Nijweide PJ, Burger EH, Feyen JH. 1986. Cells of bone: Proliferation, differentiation, and hormonal regulation. Physiol Rev 66:855-886.
-
(1986)
Physiol Rev
, vol.66
, pp. 855-886
-
-
Nijweide, P.J.1
Burger, E.H.2
Feyen, J.H.3
-
27
-
-
0026863763
-
Interleukin-6: An osteotropic factor?
-
Roodman GD. 1992. Interleukin-6: An osteotropic factor? J Bone Miner Res 7:475-478.
-
(1992)
J Bone Miner Res
, vol.7
, pp. 475-478
-
-
Roodman, G.D.1
-
28
-
-
0028912183
-
Intracellular interleukin-6 mediates platelet-derived growth factor-induced proliferation of nontransformed cells
-
Roth M, Nauck M, Tamm M, Perruchoud AP, Ziesche R, Block LH. 1995. Intracellular interleukin-6 mediates platelet-derived growth factor-induced proliferation of nontransformed cells. Proc Natl Acad Sci USA 92:1312-1316.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 1312-1316
-
-
Roth, M.1
Nauck, M.2
Tamm, M.3
Perruchoud, A.P.4
Ziesche, R.5
Block, L.H.6
-
29
-
-
0031892270
-
Potential mechanism(s) involved in the regulation of glycogen synthesis by insulin
-
Srivastava AK, Pandey SK. 1998. Potential mechanism(s) involved in the regulation of glycogen synthesis by insulin. Mol Cell Biochem 182:135-141.
-
(1998)
Mol Cell Biochem
, vol.182
, pp. 135-141
-
-
Srivastava, A.K.1
Pandey, S.K.2
-
30
-
-
0020678843
-
In vitro differentiation and calcification in a new clonal osteogenic cell line derived from newborn mouse calvaria
-
Sudo H, Kodama HA, Amagai Y, Yamamoto S, Kasai S. 1983. In vitro differentiation and calcification in a new clonal osteogenic cell line derived from newborn mouse calvaria. J Cell Biol 96:191-198.
-
(1983)
J Cell Biol
, vol.96
, pp. 191-198
-
-
Sudo, H.1
Kodama, H.A.2
Amagai, Y.3
Yamamoto, S.4
Kasai, S.5
-
31
-
-
0032185232
-
Hypoxia-induced interleukin-6 and interleukin-8 production is mediated by platelet-activating factor and platelet-derived growth factor in primary human lung cells
-
Tamm M, Bihl M, Eickelberg O, Stulz P, Perruchoud AP, Roth M. 1998. Hypoxia-induced interleukin-6 and interleukin-8 production is mediated by platelet-activating factor and platelet-derived growth factor in primary human lung cells. Am J Respir Cell Mol Biol 19:653-661.
-
(1998)
Am J Respir Cell Mol Biol
, vol.19
, pp. 653-661
-
-
Tamm, M.1
Bihl, M.2
Eickelberg, O.3
Stulz, P.4
Perruchoud, A.P.5
Roth, M.6
-
32
-
-
0028170210
-
A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)
-
Vlahos CJ, Matter WF, Hui KY, Brown RF, 1994. A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002). J Biol Chem 269:5241-5248.
-
(1994)
J Biol Chem
, vol.269
, pp. 5241-5248
-
-
Vlahos, C.J.1
Matter, W.F.2
Hui, K.Y.3
Brown, R.F.4
|