Genetics of antimicrobial resistance

Animal Biotechnology

Volumn 17, Issue 2, 2006, Pages 111-124

  Harbottle, H ^a   Thakur, S ^a   Zhao, S ^a   White, D G ^a  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

Antimicrobial resistance genes; Antimicrobial resistance mechanisms; Conjugation; Integron; Plasmid; Transposon

Indexed keywords

BACTERIA; BIODEGRADATION; CELL MEMBRANES; ENZYME KINETICS; GENETIC ENGINEERING; HEALTH CARE;

ANTIMICROBIAL RESISTANCE GENES; ANTIMICROBIAL RESISTANCE MECHANISMS; CONJUGATION; INTEGRONS; PLASMIDS; TRANSPOSONS;

ANTIBIOTICS;

ANIMALIA; BACTERIA (MICROORGANISMS);

ANTIINFECTIVE AGENT;

ANIMAL; ANIMAL DISEASE; ANTIBIOTIC RESISTANCE; BACTERIAL GENOME; BACTERIAL INFECTION; BACTERIUM; DRUG EFFECT; GENETIC TRANSFORMATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; HUMAN; INTERSPERSED REPEAT; MICROBIOLOGY; MULTIDRUG RESISTANCE; PHENOTYPE; REVIEW;

ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIA; BACTERIAL INFECTIONS; DRUG RESISTANCE, BACTERIAL; DRUG RESISTANCE, MULTIPLE, BACTERIAL; GENOME, BACTERIAL; HUMANS; INTERSPERSED REPETITIVE SEQUENCES; PHENOTYPE; TRANSFORMATION, GENETIC;

EID: 33751548698     PISSN: 10495398     EISSN: 15322378     Source Type: Journal    
DOI: 10.1080/10495390600957092     Document Type: Article

References (89)

1. Levy SB. Balancing the drug-resistance equation. Trends Microbiol 1994; 2(10):341-342.
2. Livermore DM. Bacterial resistance: origins, epidemiology, and impact. Clin Infect Dis 2003; 36(Suppl 1):S11-S23.
3. Levy SB. Multidrug resistance-a sign of the times. N Engl J Med 1998; 338(19): 1376-1378.
4. Furuya EY, Lowy FD. Antimicrobial-resistant bacteria in the community setting. Nat Rev Microbiol 2006; 4(1):36-45.
5. Salyers AA, Amabile-Cuevas CF. Why are antibiotic resistance genes so resistant to elimination? Antimicro Agents Chemother 1997; 41(11):2321-2325.
6. Adesiyun AA, Kaminjolo JS. Susceptibility to antibiotics of Escherichia coli strains isolated from diarrhoeic and non-diarrhoeic livestock in Trinidad. Rev Elev Med Vet Pays Trop 1992; 45(3-4):260-262.
7. Griggs DJ, Hall MC, Jin YF, Piddock LJ. Quinolone resistance in veterinary isolates of Salmonella. J Antimicrob Chemother 1994; 33(6): 1173-1189.
8. Johnson AM. Use of antimicrobial drugs in veterinary practice. BMJ 1998; 317(7159):665-667.
9. Piddock LJ. Does the use of antimicrobial agents in veterinary medicine and animal husbandry select antibiotic-resistant bacteria that infect man and compromise antimicrobial chemotherapy? J Antimicrob Chemother 1996; 38(1):1-3.
10. Barton MD. Does the use of antibiotics in animals affect human health? Aust Vet J 1998; 76(3): 177-180.
11. Blanco J, Cid D, Blanco JE, Blanco M, Ruiz Santa Quiteira JA, De la Fuente R. Serogroups, toxins and antibiotic resistance of Escherichia coli strains isolated from diarrhoeic lambs in Spain. Vet Microbiol 1996; 49(3-4):209-217.
12. Blanco JE, Blanco M, Mora A, Blanco J. Prevalence of bacterial resistance to quinolones and other antimicrobials among avian Escherichia coli strains isolated from septicemic and healthy chickens in Spain. J Clin Microbiol 1997; 35(8):2184-2185.
13. Davies JE. Origins, acquisition and dissemination of antibiotic resistance determinants. Ciba Found Symp 1997; 207:15-27.
14. Everett MJ, Jin YF, Ricci V, Piddock LJ. Contributions of individual mechanisms to fluoroquinolone resistance in 36 Escherichia coli strains isolated from humans and animals. Antimicrob Agents Chemother 1996; 40(10):2380-2386.
15. Gold HS, Moellering RC, Jr. Antimicrobial-drug resistance. N Engl J Med 1996; 335(19):1445-1453.
16. Kruse H, Sorum H. Transfer of multiple drug resistance plasmids between bacteria of diverse origins in natural microenvironments. Appl Environ Microbiol 1994; 60(11): 4015-4021.
17. Singh M, Chaudhry MA, Yadava JN, Sanyal SC. The spectrum of antibiotic resistance in human and veterinary isolates of Escherichia coli collected from 1984-86 in Northern India. J Antimicrob Chemother 1992; 29(2):159-168.
18. Witte W. Medical consequences of antibiotic use in agriculture. Science 1998; 279(5353): 996-997.
19. Dechet AM, Scallan E, Gensheimer K, Hoekstra R, Gunderman-King J, Lockett J, Wrigley D, Chege W, Sobel J. Outbreak of multidrug-resistant Salmonella enterica serotype Typhimurium Definitive Type 104 infection linked to commercial ground beef, Northeastern United States, 2003-2004. Clin Infect Dis 2006; 42(6):747-752.
20. Glynn MK, Bopp C, Dewitt W, Dabney P, Mokhtar M, Angulo FJ. Emergence of multidrug-resistant Salmonella enterica serotype typhimurium DT104 infections in the United States. N Engl J Med 1998; 338(19): 1333-1338.
21. CDC. National Antimicrobial Resistance Monitoring System for Enteric Bacteria (NARMS): 2003 Human Isolates Final Report. US Department of Health and Human Services, CDC 2006, Atlanta, GA.
22. Dancer SJ, Shears P, Platt DJ. Isolation and characterization of coliforms from glacial ice and water in Canada's High Arctic. J Appl Microbiol 1997; 82(5):597-609.
23. Song JS, Jeon JH, Lee JH, Jeong SH, Jeong BC, Kim SJ, Lee JH, Lee SH. Molecular characterization of TEM-type beta-lactamases identified in cold-seep sediments of Edison Seamount (south of Lihir Island, Papua New Guinea). J Microbiol 2005; 43(2):172-178.
24. Smith DH. R factor infection of Escherichia coli lyophilized in 1946. J Bacteriol 1967; 94(6):2071-2072.
25. Barlow M, Hall BG. Origin and evolution of the AmpC beta-lactamases of Citrobacter freundii. Antimicrob Agents Chemother 2002; 46(5):1190-1198.
26. Datta N, Hughes VM. Plasmids of the same Inc groups in Enterbacteria before and after the medical use of antibiotics. Nature 1983; 306(5943):616-617.
27. Hughes VM, Datta N. Conjugative plasmids in bacteria of the 'pre-antibiotic' era. Nature 1983; 302(5910):725-726.
28. D'Costa VM, McGrann KM, Hughes DW, Wright GD. Sampling the antibiotic resistome. Science 2006; 311(5759):374-377.
29. Hong HJ, Hutchings MI, Neu JM, Wright GD, Paget MS, Buttner MJ. Characterization of an inducible vancomycin resistance system in Streptomyces coelicolor reveals a novel gene (vanK) required for drug resistance. Mol Microbiol 2004; 52(4): 1107-1121.
30. Webb V, Davies J. Antibiotic preparations contain DNA: a source of drug resistance genes? Antimicrob Agents Chemother 1993; 37(11):2379-2384.
31. McDermott PF, Walker RD, White DG. Antimicrobials: modes of action and mechanisms of resistance. Int J Toxicol 2003; 22:135-143.
32. Williamson R, le Bouguenec C, Gutmann L, Horaud T. One or two low affinity penicillin-binding proteins may be responsible for the range of susceptibility of Enterococcus faecium to benzylpenicillin. J Gen Microbiol 1985; 131(8):1933-1940.
33. Michael GB, Butaye P, Cloeckaert A, Schwarz S. Genes and mutations conferring antimicrobial resistance in Salmonella. An update. Microbes and Infection 2006;8(7): 1898-1914.
34. Gootz TD. The forgotten Gram-negative bacilli: what genetic deteminants are telling us about the spread of antibiotic resistance. Biochem Pharmacol 2006; 71 (7): 1073-1084.
35. Gootz TD. Global dissemination of beta-lactamases mediating resistance to cephalosporins and carbapenems. Expert Rev Anti Infect Ther 2004; 2(2): 317-327.
36. Bradford PA. Extended-spectrum of beta-lactamases in the 21st century: characterization, epidemiology, and dectection of this important resistance threat. Clin Microbiol Rev 2001; 14(4):933-951.
37. Poole K. Miltidrug resistance in Gram-negative bacteria. Curr Opin Microbiol 2001; 4(5):500-508.
38. Fluit AC, Visser MR, Schmitz FJ. Molecular detection of antimicrobial resistance. Clin Microbiol Rev 2001; 14(4):836-871.
39. Piddock LJ. Clinically relevant chromosomally encoded multidrug resistance efflux pumps in bacteria. Clin Microbiol Rev 2006; 19(2):382-402.
40. Wright GD. Bacterial resistance to antibiotics: enzymatic degradation and modification. Adv Drug Deliv Rev 2005; 57(10):1451-1470.
41. Robicsek A, Strahilevitz J, Jacoby GA, Macielag M, Abbanat D, Park CH, Bush K, Hooper DC. Fluoroquinolone-modifying enzyme: a new adaptation of a common aminoglycoside acetyltransferase. Nat Med 2006; 12(1):83-88.
42. Poole K. Outer membranes and efflux: the path to multidrug resistance in Gram-negative bacteria. Curr Pharm Biotechnol 2002; 3(2):77-98.
43. Achouak W, Heulin T, Pages JM. Multiple facets of bacterial porins. FEMS Microbiol Lett 2001; 199(1): 1-7.
44. Nummila K, Kilpelainen I, Zahringer U, Vaara M, Helander IM. Lipopolysaccharides of polymyxin B-resistant mutants of Escherichia coli are extensively substituted by 2-aminoethyl pyrophosphate and contain aminoarabinose in lipid A. Mol Microbiol 1995; 16(2):271-278.
45. Helander IM, Kilpelainen I, Vaara M. Increased substitution of phosphate groups in lipopolysaccharides and lipid A of the polymyxin-resistant pmrA mutants of Salmonella typhimurium: a 31P-NMR study. Mol Microbiol 1994; 11(3):481-487.
46. Li XZ, Nikaido H. Efflux-mediated drug resistance in bacteria. Drugs 2004; 64(2): 159-204.
47. Poole K. Efflux-mediated multiresistance in Gram-negative bacteria. Clin Microbiol Infect 2004; 10(1):12-26.
48. Bush K, Jacoby GA, Medeiros AA. A functional classification scheme for beta-lactamases and its correlation with molecular structure. Antimicrob Agents Chemother 1995; 39(6): 1211-1233.
49. Piddock LJ. Mechanisms of resistance to fluoroquinolones: state-of-the-art 1992-1994. Drugs 1995; 49(Suppl 2):29-35.
50. Frost LS, Leplae R, Summers AO, Toussaint A. Mobile genetic elements: the agents of open source evolution. Nat Rev Microbiol 2005; 3(9):722-732.
51. Rychlik I, Gregorova D, Hradecka H. Distribution and function of plasmids in Salmonella enterica. Vet Microbiol 2006; 112(1):1-10.
52. Carattoli A, Miriagou V, Bertini A, Loli A, Colinon C, Villa L, Whichard JM, Rossoloni GM. Replicon typing of plasmids encoding resistance to newer beta-lactams. Emerg Infect Dis 2006; 12(7): 1145-1148.
53. Watanabe T, Fukasawa T. Episome-mediated transfer of drung resistance in Enterobacteriaceace. I. Transfer of resistance factors by conjugation. J Bacteriol 1961; 81:669-678.
54. Gay K, Robicsek A, Strahilevitz J, Park CH, Jacoby G, Barrett TJ, Medalla F, Chiller TM, Hooper DC. Plasmid-mediated quinolone resistance in non-Typhi serotypes of Salmonella enterica. Clin Infect Dis 2006; 43(3):297-304.
55. Jacoby GA, Walsh KE, Mills DM, Walker VJ, Oh H, Robicsek A, Hooper DC. qnrB, another plasmid-mediated gene for quinolone resistance. Antimicrob Agents Chemother 2006; 50(4): 1178-1182.
56. Li XZ. Quinolone resistance in bacteria: emphasis on plasmid-mediated mechanisms. Int J Antimicrob Agents 2005; 25(6):453-463.
57. Sherley M, Gordon DM, Collignon PJ. Evolution of multi-resistance plasmids in Australian clinical isolates of Escherichia coli. Microbiology 2004; 150(Pt 5): 1539-1546.
58. Gebreyes WA, Thakur S. Multidrug-resistant Salmonella enterica serovar Muenchen from pigs and humans and potential interserovar transfer of antimicrobial resistance. Antimicrob Agents Chemother 2005; 49(2):503-511.
59. Martinez-Martinez L, Pascual A, Jacoby GA. Quinolone resistance from a transferable plasmid. Lancet 1998; 351(9105):797-799.
60. Tran JH, Jacoby GA. Mechanism of plasmid-mediated quinolone resistance. Proc Natl Acad Sci USA 2002; 99(8):5638-5642.
61. Poirel L, Cabanne L, Vahaboglu H, Nordmann P. Genetic environment and expression of the extended-spectrum beta-lactamase blaPER-1 gene in gram-negative bacteria. Antimicrob Agents Chemother 2005; 49(5): 1708-1713.
62. Wang M, Tran JH, Jacoby GA, Zhang Y, Wang F, Hooper DC. Plasmid-mediated quinolone resistance in clinical isolates of Escherichia coli from Shanghai, China. Antimicrob Agents Chemother 2003; 47(7):2242-2248.
63. Salyers AA, Shoemaker NB, Stevens AM, Li LY. Conjugative transposons: an unusual and diverse set of integrated gene transfer elements. Microbiol Rev 1995; 59(4):579-590.
64. Hall RM, Collis CM, Kim MJ, Partridge SR, Recchia GD, Stokes HW. Mobile gene cassettes and integrons in evolution. Ann NY Acad Sci 1999; 870:68-80.
65. Recchia GD, Hall RM. Origins of the mobile gene cassettes found in integrons. Trends Microbiol 1997; 5(10):389-394.
66. White DG, Zhao S, Sudler R, Ayers S, Friedman S, Chen S, McDermott PF, McDermott S, Wagner DD, Meng J. The isolation of antibiotic-resistance salmonella from retail ground meats. N Engl J Med 2001; 345(16):1147-1154.
67. Goldstein C, Lee MD, Sanchez S, Hudson C, Phillips B, Register B, Grady M, Liebert C, Summers AO, White DG, Maurer JJ. Incidence of class 1 and 2 integrases in clinical and commensal bacteria from livestock, companion animals, and exotics. Antimicrob Agents Chemother 2001; 45(3):723-726.
68. Zhao S, Qaiyumi S, Friedman S, Singh R, Foley SL, White DG, McDermott PF, Donkar T, Bolin C, Munro S, Baron EJ, Walker RD. Characterization of Salmonella enterica serotype newport isolated from humans and food animals. J Clin Microbiol 2003; 41(12):5366-5371.
69. White DG, Zhao S, McDermott PF, Ayers S, Friedman S, Sherwood J, Breider-Foley M, Nolan LK. Characterization of integron mediated antimicrobial resistance in Salmonella isolated from diseased swine. Can J Vet Res 2003; 67(1):39-47.
70. Besser TE, Gay CC, Gay JM, Hancock DD, Rice D, Pritchett LC, Erickson ED. Salmonellosis associated with S typhimurium DT104 in the USA. Vet Rec 1997; 140(3):75.
71. Ng LK, Mulvey MR, Martin I, Peters GA, Johnson W. Genetic characterization of antimicrobial resisance in Canadian isolates of Salmonella serovar Typhimurium DT104. Antimicrob Agents Chemother 1999; 43(12):3018-3021.
72. Threlfall EJ, Frost JA, Ward LR, Rowe B. Epidemic in cattle and humans of Salmonella typhimurium DT 104 with chromosomally integrated multiple drug resistance. Vet Rec 1994; 134(22):577.
73. Mulvey MR, Boyd DA, Olson AB, Doublet B, Cloeckaert A. The genetics of Salmonella genomic island 1. Microbes Infect 2006; 8(7):1915-1922.
74. Butaye P, Michael GB, Schwarz S, Barrett TJ, Brisabois A, White DG. The clonal spread of multidrug-resistant non-typhi Salmonella serotypes. Microbes Infect 2006; 8(7): 1891-1897.
75. Schmieger H, Schicklmaier P. Transduction of multiple drug resistance of Salmonella enterica serovar typhimurium DT104. FEMS Microbiol Lett 1999; 170(1):251-256.
76. Arcangioli MA, Leroy-Setrin S, Martel JL, Chaslus-Dancla E. A new chloramphenicol and florfenicol resistance gene flanked by two integron structures in Salmonella typhimurium DT104. FEMS Microbiol Lett 1999; 174(2):327-332.
77. Collis CM, Grammaticopoulos G, Briton J, Stokes HW, Hall RM. Site-specific insertion of gene cassettes into integrons. Mol Microbiol 1993; 9(1):41-52.
78. Mazel D, Dychinco B, Webb VA, Davies J. A distinctive class of integron in the Vibrio cholerate genome. Science 1998; 280(5363):605-608.
79. Rowe-Magnus DA, Guerout AM, Mazel D. Super-integrons. Res Microbiol 1999; 150(9-10): 641-651.
80. Toleman MA, Bennett PM, Walsh TR. Common regions e.g. orf513 and antibiotic resistance: IS91-like elements evolving complex class 1 integrons. J Antimicrob Chemother 2006; 58(1):1-6.
81. Beaber JW, Hochhut B, Waldor MK. Genomic and functional analyses of SXT, an integrating antibiotic resistance gene transfer eleement derived from Vibrio cholerae. J Bacterio1 2002; 184(15):4259-4269.
82. Sandvang D, Aarestrup FM, Jensen LB. Characterisation of integrons and antibiotic resistance genes in Danish multiresistance Salmonella enterica Typhimurium DT104. FEMS Microbiol Lett 1997; 157(1): 177-181.
83. Hall RM. Mobile gene cassettes and integrons: moving antibiotic resistance genes in gram-negative bacteria. Ciba Found Symp 1997; 207:192-202.
84. Olsen JE. Antibiotic reistance: genetic mechanisms and mobility. Acta Vet Scand Suppl 1999; 92:15-22.
85. Blahova J, Kralikova K, Krcmery V, Jezek P. Low-Frequency transduction of imipenem resistance and high-frequency transduction of ceftazidime and aztreonam resistance by the bacteriophage AP-151 isolated from a Pseudomonas aeruginosa strain. J Chemother 2000; 12(6):482-486.
86. Wierup M. The experience of reducing antibiotics used in animal production in the Nordic countries. Int J Antimicrob Agents 2001; 18(3):287-290.
87. Aarestrup FM, Seyfarth AM, Emborg HD, Pedersen K, Hendriksen RS, Bager F. Effect of abolishment of the use of antimicrobial agents for growth promotion on occurrence of antimicrobial resistance in fecal enterococci from food animals in Denmark. Antimicrob Agents Chemother 2001; 45(7):2054-2059.
88. American Society for Microbiology Antimicrob. Report of the ASM task force on antibiotic resistance. Antimicrob Agents Chemother 1995; Suppl., 1-23.
89. Munford RS, Murphy TV. Antimicrobial resistance in Streptococcus pneumoniae: can immunization prevent its spread? J Investig Med 1994; 42(4):613-621.