Lactational exposure to malathion inhibits brain acetylcholinesterase in mice

NeuroToxicology

Volumn 27, Issue 6, 2006, Pages 1101-1105

  Silva, Aline Preve da ^a   Meotti, Flávia Carla ^a   Santos, Adair R S ^a   Farina, Marcelo ^a  

^a FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

Author keywords

Acetylcholinesterase; Lactational exposure; Malathion; Neurotoxicity; Organophosphorus

Indexed keywords

ACETYLCHOLINESTERASE; BRAIN ENZYME; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; MALATHION; ORGANOPHOSPHATE PESTICIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN LEVEL; BREAST MILK; CHEMICAL PARAMETERS; CHOLINESTERASE INHIBITION; CONTROLLED STUDY; DOSE RESPONSE; ENZYME ACTIVITY; EXPOSURE; FEMALE; LACTATION; LIPID PEROXIDATION; MALE; MOUSE; NEUROTOXICITY; NEWBORN; NEWBORN PERIOD; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROGENY; PROTEIN DETERMINATION; SUCKLING;

ACETYLCHOLINESTERASE; ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; BRAIN; CHOLINESTERASE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GLUTATHIONE PEROXIDASE; LACTATION; LIPID PEROXIDATION; MALATHION; MALE; MICE; RANDOM ALLOCATION;

EID: 33751531099     PISSN: 0161813X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuro.2006.04.002     Document Type: Article

References (44)

1. Abdel-Rahman A., Dechkovskaia A.M., Goldstein L.B., et al. Neurological deficits induced by malathion, DEET, and permethrin, alone or in combination in adult rats. J Toxicol Environ Health A 67 (2004) 331-356
2. Abou-Donia M.B. Organophosphorus ester-induced chronic neurotoxicity. Arch Environ Health 58 (2003) 484-497
3. Ahmed R.S., Seth V., Pasha S.T., and Banerjee B.D. Influence of dietary ginger (Zingiber officinales Rosc) on oxidative stress induced by malathion in rats. Food Chem Toxicol 38 (2000) 443-450
4. Akhgari M., Abdollahi M., Kebryaeezadeh A., Hosseini R., and Sabzevari O. Biochemical evidence for free radical-induced lipid peroxidation as a mechanism for subchronic toxicity of malathion in blood and liver of rats. Hum Exp Toxicol 22 (2003) 205-211
5. Banerjee B.D., Seth V., Bhattacharya A., Pasha S.T., and Chakraborty A.K. Biochemical effects of some pesticides on lipid peroxidation and free-radical scavengers. Toxicol Lett 107 (1999) 33-47
6. Battu R.S., Singh B., and Kang B.K. Contamination of liquid milk and butter with pesticide residues in the Ludhiana district of Punjab state, India. Ecotoxicol Environ Saf 59 (2004) 324-331
7. Berkowitz G.S., Obel J., Deych E., et al. Exposure to indoor pesticides during pregnancy in a multiethnic, urban cohort. Environ Health Perspect 111 (2003) 79-84
8. Bouchard M., Gosselin N.H., Brunet R.C., Samuel O., et al. A toxicokinetic model of malathion and its metabolites as a tool to assess human exposure and risk through measurements of urinary biomarkers. Toxicol Sci. 73 (2003) 182-194
9. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72 (1976) 248-254
10. Brocardo P.S., Pandolfo P., Takahashi R.N., Rodrigues A.L., and Dafre A.L. Antioxidant defenses and lipid peroxidation in the cerebral cortex and hippocampus following acute exposure to malathion and/or zinc chloride. Toxicology 207 (2005) 283-291
11. Carlberg I., and Mannervik B. Glutathione reductase. Methods Enzymol 113 (1985) 484-490
12. Chanda S.M., Harp P., Liu J., and Pope C.N. Comparative developmental and maternal neurotoxicity following acute gestational exposure to chlorpyrifos in rats. J Toxicol Environ Health 44 (1995) 189-202
13. Curl C.L., Fenske R.A., Kissel J.C., et al. Evaluation of take-home organophosphorus pesticide exposure among agricultural workers and their children. Environ Health Perspect 110 (2002) A787-A792
14. Ellman G.L. Tissue sulfhydryl groups. Arch Biochem Biophys 82 (1959) 70-77
15. Ellman G.L., Courtney K.D., Andres Jr. V., and Feather-Stone R.M. A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem Pharmacol 7 (1961) 88-95
16. Farina M., Brandão R., de Lara F.S., et al. Profile of nonprotein thiols, lipid peroxidation and delta-aminolevulinate dehydratase activity in mouse kidney and liver in response to acute exposure to mercuric chloride and sodium selenite. Toxicology 184 (2003) 179-187
17. Franco J.L., Teixeira A., Meotti F.C., et al. Cerebellar thiol status and motor deficit after lactational exposure to methylmercury. Environ Res 102 (2006) 22-28
18. Fenske R.A., Lu C., Barr D., and Needham L. Children's exposure to chlorpyrifos and parathion in an agricultural community in central Washington State. Environ Health Perspect 110 (2002) 549-553
19. Hazarika A., Sarkar S.N., Hajare S., Kataria M., and Malik J.K. Influence of malathion pretreatment on the toxicity of anilofos in male rats: a biochemical interaction study. Toxicology 185 (2003) 1-8
20. Hill Jr. R.H., Head S.L., Baker S., et al. Pesticide residues in urine of adults living in the United States: reference range concentrations. Environ Res 71 (1995) 99-108
21. John S., Kale M., Rathore N., and Bhatnagar D. Protective effect of vitamin E in dimethoate and malathion induced oxidative stress in rat erythrocytes. J Nutr Biochem 12 (2001) 500-504
22. Komori T., Yamane K., Nagayama T., Shibata K., Nozaki H., and Takeuchi M. A case of delayed myeloneuropathy due to malathion intoxication. No To Shinkei 43 (1991) 969-974
23. Kunz C., Rodriguez-Palmero M., Koletzko B., and Jensen R. Nutritional and biochemical properties of human milk. Part I. General aspects, proteins, and carbohydrates. Clin Perinatol 26 (1999) 307-333
24. Kwong T.C. Organophosphate pesticides: biochemistry and clinical toxicology. Ther Drug Monit 24 (2002) 144-149
25. Manfroi C.B., Schwalm F.D., Cereser V., et al. Maternal milk as methylmercury source for suckling mice: neurotoxic effects involved with the cerebellar glutamatergic system. Toxicol Sci 81 (2004) 172-178
26. McCauley L.A., Lasarev M.R., Higgins G., et al. Work characteristics and pesticide exposures among migrant agricultural families: a community-based research approach. Environ Health Perspect 109 (2001) 533-538
27. Oddy W.H. Breastfeeding and asthma in children: findings from a West Australian study. Breastfeed Rev 8 (2000) 5-11
28. Ohkawa H., Ohishi N., and Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 95 (1979) 351-358
29. Pedrajas J.R., Peinado J., and Lopez-Barea J. Oxidative stress in fish exposed to model xenobiotics. Oxidatively modified forms of Cu,Zn-superoxide dismutase as potential biomarkers. Chem Biol Interact 98 (1995) 267-282
30. Pope C.N., and Chakraborti T.K. Dose-related inhibition of brain and plasma cholinesterase in neonatal and adult rats following sublethal organophosphate exposures. Toxicology 73 (1992) 35-43
31. Pope C.N., Chakraborti T.K., Chapman M.L., Farrar J.D., and Arthun D. Comparison of in vivo cholinesterase inhibition in neonatal and adult rats by three organophosphorothioate insecticides. Toxicology 68 (1991) 51-61
32. Ranjbar A., Pasalar P., and Abdollahi M. Induction of oxidative stress and acetylcholinesterase inhibition in organophosphorous pesticide manufacturing workers. Hum Exp Toxicol 21 (2002) 179-182
33. Salas J.H., Gonzalez M.M., Noa M., et al. Organophosphorus pesticide residues in Mexican commercial pasteurized milk. J Agric Food Chem 51 (2003) 4468-4471
34. Sanghi R., Pillai M.K., Jayalekshmi T.R., and Nair A. Organochlorine and organophosphorus pesticide residues in breast milk from Bhopal, Madhya Pradesh, India. Hum Exp Toxicol 22 (2003) 73-76
35. Simcox N.J., Camp J., Kalman D., et al. Farmworker exposure to organophosphorus pesticide residues during apple thinning in central Washington State. Am Ind Hyg Assoc J 60 (1999) 752-761
36. Slotkin T.A. Guidelines for developmental neurotoxicity and their impact on organophosphate pesticides: a personal view from an academic perspective. Neurotoxicology 25 (2004) 631-640
37. Slotkin T.A. Cholinergic systems in brain development and disruption by neurotoxicants: nicotine, environmental tobacco smoke, organophosphates. Toxicol Appl Pharmacol 198 (2004) 132-151
38. Slotkin T.A., Oliver C.A., and Seidler F.J. Critical periods for the role of oxidative stress in the developmental neurotoxicity of chlorpyrifos and terbutaline, alone or in combination. Brain Res Dev Brain Res 157 (2005) 172-180
39. Song X., Seidler F.J., Saleh J.L., Zhang J., Padilla S., and Slotkin T.A. Cellular mechanisms for developmental toxicity of chlorpyrifos: targeting the adenylyl cyclase signaling cascade. Toxicol Appl Pharmacol 145 (1997) 158-174
40. Srikanth N.S., and Seth P.K. Alterations in xenobiotic metabolizing enzymes in brain and liver of rats coexposed to endosulfan and malathion. J Appl Toxicol 10 (1990) 157-160
41. Verma R.S., and Srivastava N. Chlorpyrifos induced alterations in levels of thiobarbituric acid reactive substances and glutathione in rat brain. Indian J Exp Biol 39 (2001) 174-177
42. Vidair C.A. Age dependence of organophosphate and carbamate neurotoxicity in the postnatal rat: extrapolation to the human. Toxicol Appl Pharmacol 196 (2004) 287-302
43. Wendel A. Glutathione peroxidase. Methods Enzymol 77 (1981) 325-333
44. Whyatt R.M., Camann D.E., Kinney P.L., et al. Residential pesticide use during pregnancy among a cohort of urban minority women. Environ Health Perspect 110 (2002) 507-514