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Volumn 73, Issue 1, 2003, Pages 182-194

A toxicokinetic model of malathion and its metabolites as a tool to assess human exposure and risk through measurements of urinary biomarkers

Author keywords

Dicarboxylic acids; Malathion; Monocarboxylic acids; Phosphoric derivatives; Risk assessment; Toxicokinetics

Indexed keywords

BIOLOGICAL MARKER; CARBOXYLIC ACID; DICARBOXYLIC ACID; MALATHION; PHOSPHOROTHIOIC ACID DERIVATIVE; PHOSPHORUS DERIVATIVE;

EID: 0038324384     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/kfg061     Document Type: Article
Times cited : (59)

References (34)
  • 3
    • 0017550565 scopus 로고
    • Malathion exposure studies. Determination of mono-and dicarboxylic acids and alkyl phosphates in urine
    • Bradway, D. E., and Shafik, T. M. (1977). Malathion exposure studies. Determination of mono-and dicarboxylic acids and alkyl phosphates in urine. J. Agric. Food Chem. 25, 1342-1344.
    • (1977) J. Agric. Food Chem. , vol.25 , pp. 1342-1344
    • Bradway, D.E.1    Shafik, T.M.2
  • 6
    • 0037025549 scopus 로고    scopus 로고
    • Biological monitoring of exposure to organophosphate pesticides
    • Cocker, J., Mason, H. J., Garfitt, S. J., and Jones, K. (2002). Biological monitoring of exposure to organophosphate pesticides. Toxicol. Lett. 134, 97-103.
    • (2002) Toxicol. Lett. , vol.134 , pp. 97-103
    • Cocker, J.1    Mason, H.J.2    Garfitt, S.J.3    Jones, K.4
  • 8
    • 0022493425 scopus 로고
    • Biological monitoring of agricultural workers exposed to pesticides: II. Monitoring of intact pesticides and their metabolites
    • Coye, M. J., Lowe, J. A., and Maddy, K. J. (1986). Biological monitoring of agricultural workers exposed to pesticides: II. Monitoring of intact pesticides and their metabolites. J. Occup. Med. 28, 628-636.
    • (1986) J. Occup. Med. , vol.28 , pp. 628-636
    • Coye, M.J.1    Lowe, J.A.2    Maddy, K.J.3
  • 9
    • 0032779201 scopus 로고    scopus 로고
    • A phase-1 volunteer study to establish the degree of absorption and effect on cholinesterase activity of four head lice preparations containing malathion
    • Dennis, G. A., and Lee, P. N. (1999). A phase-1 volunteer study to establish the degree of absorption and effect on cholinesterase activity of four head lice preparations containing malathion. Clin. Drug Invest. 18, 105-115.
    • (1999) Clin. Drug Invest. , vol.18 , pp. 105-115
    • Dennis, G.A.1    Lee, P.N.2
  • 11
    • 0038300281 scopus 로고    scopus 로고
    • Bilan des Ventes de Pesticides au Québec en 1997
    • Environnement Québec Gouvernement du Québec, Québec, Canada
    • Environnement Québec (2002). Bilan des Ventes de Pesticides au Québec en 1997. Gouvernement du Québec, Québec, Canada.
    • (2002)
  • 12
    • 0016373013 scopus 로고
    • Percutaneous penetration of some pesticides and herbicides in man
    • Feldmann, R. J., and Maibach, H. I. (1974). Percutaneous penetration of some pesticides and herbicides in man. Toxicol. Appl. Pharmacol. 28, 126-132.
    • (1974) Toxicol. Appl. Pharmacol. , vol.28 , pp. 126-132
    • Feldmann, R.J.1    Maibach, H.I.2
  • 13
    • 0023783808 scopus 로고
    • Correlation of fluorescent tracer measurements of dermal exposure and urinary metabolite excretion during occupational exposure to malathion
    • Fenske, R. A. (1988). Correlation of fluorescent tracer measurements of dermal exposure and urinary metabolite excretion during occupational exposure to malathion. Am. Ind. Hyg. Assoc. J. 49, 438-444.
    • (1988) Am. Ind. Hyg. Assoc. J. , vol.49 , pp. 438-444
    • Fenske, R.A.1
  • 14
    • 0024317223 scopus 로고
    • Method for the determination of dialkyl phosphate metabolites in urine for studies of human exposure to malathion
    • Fenske, R. A., and Leffingwell, J. T. (1989). Method for the determination of dialkyl phosphate metabolites in urine for studies of human exposure to malathion. J. Agric. Food Chem. 37, 995-998.
    • (1989) J. Agric. Food Chem. , vol.37 , pp. 995-998
    • Fenske, R.A.1    Leffingwell, J.T.2
  • 15
    • 0014175174 scopus 로고
    • The significance of blood cholinesterase activity measurements
    • Gage, J. C. (1967). The significance of blood cholinesterase activity measurements. Residue Rev. 18, 159-173.
    • (1967) Residue Rev. , vol.18 , pp. 159-173
    • Gage, J.C.1
  • 16
    • 0002397806 scopus 로고
    • Clinical presentation and diagnosis of acute organophosphorus insecticide and carbamate poisoning
    • (B. Ballantyne and T. C. Marrs, Eds.), Butterworth-Heinemann, Oxford
    • Heath, A. J. W., and Vale, J. A. (1992). Clinical presentation and diagnosis of acute organophosphorus insecticide and carbamate poisoning. In Clinical and Experimental Toxicology of Organophosphates and Carbamates (B. Ballantyne and T. C. Marrs, Eds.), pp. 513-519. Butterworth-Heinemann, Oxford.
    • (1992) Clinical and Experimental Toxicology of Organophosphates and Carbamates , pp. 513-519
    • Heath, A.J.W.1    Vale, J.A.2
  • 17
    • 0038639211 scopus 로고    scopus 로고
    • Jellinek, Schwartz, and Connolly, Inc. Cheminova, Lemvig, Denmark. Unpublished report, CHA Doc. No.: 299 FYF Amdt-4. Submitted to EPA on 5/17/00, MRID 45125601
    • Jellinek, Schwartz, and Connolly, Inc. (2000). The Effects and Pharmacological Disposition of a Single Oral Dose of Malathion Administered to Human Volunteers. Cheminova, Lemvig, Denmark. Unpublished report, CHA Doc. No.: 299 FYF Amdt-4. Submitted to EPA on 5/17/00, MRID 45125601.
    • (2000) The Effects and Pharmacological Disposition of a Single Oral Dose of Malathion Administered to Human Volunteers
  • 18
    • 0034114205 scopus 로고    scopus 로고
    • Malathion deposition, metabolite clearance, and cholinesterase status of date dusters and harvester in California
    • Krieger, R. I., and Dinoff, T. M. (2000). Malathion deposition, metabolite clearance, and cholinesterase status of date dusters and harvester in California. Arch. Environ. Contam. Toxicol. 38, 546-553.
    • (2000) Arch. Environ. Contam. Toxicol. , vol.38 , pp. 546-553
    • Krieger, R.I.1    Dinoff, T.M.2
  • 19
    • 0019905874 scopus 로고
    • Effect of exposure to organophosphorus compounds on cholinesterase in workers removing poisonous depots
    • Larsen, K.-O., and Hanel, H. K. (1982). Effect of exposure to organophosphorus compounds on cholinesterase in workers removing poisonous depots. Scand. J. Environ. Health 8, 222-228.
    • (1982) Scand. J. Environ. Health , vol.8 , pp. 222-228
    • Larsen, K.-O.1    Hanel, H.K.2
  • 20
    • 0022500282 scopus 로고
    • Kinetics of carbaryl and malathion in combination in the rat
    • Lechner, D. W., and Abdel-Rahman, M. S. (1986). Kinetics of carbaryl and malathion in combination in the rat. J. Toxicol. Environ. Health 19, 241-256.
    • (1986) J. Toxicol. Environ. Health , vol.19 , pp. 241-256
    • Lechner, D.W.1    Abdel-Rahman, M.S.2
  • 21
    • 0032502754 scopus 로고    scopus 로고
    • Comparative pre-synaptic neurochemical changes in rat striatum following exposure to chlorpyrifos or parathion
    • Liu, J, and Pope, C. N. (1998). Comparative pre-synaptic neurochemical changes in rat striatum following exposure to chlorpyrifos or parathion. J. Toxicol. Environ. Health, Part A 53, 531-544.
    • (1998) J. Toxicol. Environ. Health, Part A , vol.53 , pp. 531-544
    • Liu, J.1    Pope, C.N.2
  • 23
    • 0015113711 scopus 로고
    • Regional variation in percutaneous penetration in man: Pesticides
    • Maibach, H. I., Feldmann, R. J., Milby, T. H., and Serat, W. F. (1971). Regional variation in percutaneous penetration in man: Pesticides. Arch. Environ. Health 23, 208-211.
    • (1971) Arch. Environ. Health , vol.23 , pp. 208-211
    • Maibach, H.I.1    Feldmann, R.J.2    Milby, T.H.3    Serat, W.F.4
  • 24
    • 0035930870 scopus 로고    scopus 로고
    • Gas chromatographic-tandem mass spectrometric analytical method for the study of inhalation, potential dermal, and actual exposure of agricultural workers to the pesticide malathion
    • Márquez, M. C., Arrebola, F. J., Egea González, F. J., Castro-Cano, M. L., and Martínez Vidal, J. L. (2001). Gas chromatographic-tandem mass spectrometric analytical method for the study of inhalation, potential dermal, and actual exposure of agricultural workers to the pesticide malathion. J. Chromatogr. A 939, 79-89.
    • (2001) J. Chromatogr. A , vol.939 , pp. 79-89
    • Márquez, M.C.1    Arrebola, F.J.2    Egea González, F.J.3    Castro-Cano, M.L.4    Martínez Vidal, J.L.5
  • 25
    • 0009587794 scopus 로고
    • Plasma and red blood cholinesterase activity as indications of the threshold of incipient toxicity of ethyl-p-nitrophenyl thionobenzene-phosphonate (EPN) and malathion in human beings
    • Moeller, H. C., and Rider, J. A. (1962). Plasma and red blood cholinesterase activity as indications of the threshold of incipient toxicity of ethyl-p-nitrophenyl thionobenzene-phosphonate (EPN) and malathion in human beings. Toxicol. Appl. Pharmacol. 4, 123-130.
    • (1962) Toxicol. Appl. Pharmacol. , vol.4 , pp. 123-130
    • Moeller, H.C.1    Rider, J.A.2
  • 27
    • 0038639204 scopus 로고
    • Malathion metabolism and disposition in mammals
    • Rabovsky, J., and Brown, J. P. (1993). Malathion metabolism and disposition in mammals. J. Occup. Med. Toxicol. 2, 131-168.
    • (1993) J. Occup. Med. Toxicol. , vol.2 , pp. 131-168
    • Rabovsky, J.1    Brown, J.P.2
  • 28
  • 29
    • 0023734558 scopus 로고
    • On the validity of the steady-state approximation of enzyme kinetics
    • Segel, L. A. (1988). On the validity of the steady-state approximation of enzyme kinetics. Bull. Math. Biol. 50, 579-593.
    • (1988) Bull. Math. Biol. , vol.50 , pp. 579-593
    • Segel, L.A.1
  • 30
    • 0024731820 scopus 로고
    • The Quasi-Steady State Approximation: A case study in pertubation
    • Segel, L. A., and Slemrod, M. (1989). The Quasi-Steady State Approximation: A case study in pertubation. SIAM Rev. 31, 446-476.
    • (1989) SIAM Rev. , vol.31 , pp. 446-476
    • Segel, L.A.1    Slemrod, M.2
  • 31
    • 0028295863 scopus 로고
    • Clinical effects of organophosphorus cholinesterases inhibitors
    • Sidell, F. R. (1994). Clinical effects of organophosphorus cholinesterases inhibitors. J. Appl. Toxicol. 14, 111-113.
    • (1994) J. Appl. Toxicol. , vol.14 , pp. 111-113
    • Sidell, F.R.1
  • 32
    • 0037025546 scopus 로고    scopus 로고
    • Monitoring of pesticide applicators for potential dermal exposure to malathion and biomarkers in urine
    • Tuomainen, A., Kangas, J. A., Meuling, W. J. A., and Glass, R. C. (2002). Monitoring of pesticide applicators for potential dermal exposure to malathion and biomarkers in urine. Toxicol. Lett. 134, 125-132.
    • (2002) Toxicol. Lett. , vol.134 , pp. 125-132
    • Tuomainen, A.1    Kangas, J.A.2    Meuling, W.J.A.3    Glass, R.C.4
  • 33
    • 0037624815 scopus 로고    scopus 로고
    • U.S. EPA Office of Prevention, Pesticides, and Toxic Substances, Environmental Protection Agency, Washington, DC
    • U.S. EPA (2000). Malathion. Office of Prevention, Pesticides, and Toxic Substances, Environmental Protection Agency, Washington, DC.
    • (2000) Malathion
  • 34
    • 0020533013 scopus 로고
    • Malathion percutaneous absorption after repeated administration to man
    • Wester, R. C., Maibach, H. I., Bucks, D. A. W., and Guy, R. H. (1983). Malathion percutaneous absorption after repeated administration to man. Toxicol. Appl. Pharmacol. 68, 116-119.
    • (1983) Toxicol. Appl. Pharmacol. , vol.68 , pp. 116-119
    • Wester, R.C.1    Maibach, H.I.2    Bucks, D.A.W.3    Guy, R.H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.