M1 muscarinic receptors inhibit L-type Ca2+ current and M-current by divergent signal transduction cascades

Journal of Neuroscience

Volumn 26, Issue 45, 2006, Pages 11588-11598

  Liu, Liwang ^a   Zhao, Rubing ^a   Bai, Yan ^a   Stanish, Lee F ^a   Evans, James E ^a   Sanderson, Michael J ^a   Bonventre, Joseph V ^b   Rittenhouse, Ann R ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Arachidonic acid; Calcium current; M1 muscarinic; Phosphatidylinositol 4,5 bisphosphate; Phospholipase A 2; PIP2; Plasticity; Superior cervical ganglion; Sympathetic

Indexed keywords

ARACHIDONIC ACID; CALCIUM; MUSCARINIC M1 RECEPTOR; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PHOSPHOLIPASE A2; PHOSPHOLIPID; WORTMANNIN; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL L TYPE; ENZYME INHIBITOR; MESSENGER RNA; PHOSPHOLIPASE A; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT;

ANIMAL CELL; ARTICLE; CALCIUM CURRENT; CERVICAL GANGLION; CONTROLLED STUDY; NERVE CELL; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; CELL CULTURE; CELL MEMBRANE POTENTIAL; COMPARATIVE STUDY; CYTOLOGY; DRUG EFFECT; DRUG INTERACTION; IMMUNOHISTOCHEMISTRY; MASS FRAGMENTOGRAPHY; METHODOLOGY; MOUSE; MOUSE MUTANT; NERVE CELL INHIBITION; NEWBORN; PATCH CLAMP; PHYSIOLOGY; RADIATION EXPOSURE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPRAGUE DAWLEY RAT; SUPERIOR CERVICAL GANGLION;

ANIMALS; ANIMALS, NEWBORN; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, L-TYPE; CELLS, CULTURED; DRUG INTERACTIONS; ENZYME INHIBITORS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; IMMUNOHISTOCHEMISTRY; MEMBRANE POTENTIALS; MICE; MICE, KNOCKOUT; NEURAL INHIBITION; NEURONS; PATCH-CLAMP TECHNIQUES; PHOSPHOLIPASES A; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, MUSCARINIC M1; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; SUPERIOR CERVICAL GANGLION;

EID: 33751118238     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2102-06.2006     Document Type: Article

References (53)

1. 2+ channels. Biophys J 83:3256-3267.
2. 2. Nature 390:622-625.
3. 2 knockout mouse. J Neurochem 87:1471-1477.
4. + current in a vertebrate neuron. Nature 283:673-676.
5. Delmas P, Brown DA (2005) Pathways modulating neural KCNQ/M (Kv7) potassium channels. Nat Rev Neurosci 6:850-862.
6. 2 superfamily of signal transduction enzymes. Trends Biochem Sci 22:1-2.
7. 2 assay for biochemical and cellular activity measurements. Chem Biol 9:795-803.
8. Ford CP, Stemkowski PL, Light PE, Smith PA (2003) Experiments to test the role of phosphatidylinositol 4,5-bisphosphate in neurotransmitter-induced M-channel closure in bullfrog sympathetic neurons. J Neurosci 23:4931-4941.
9. 2+ sensitization of rabbit smooth muscle. J Physiol (Lond) 500:95-109.
10. 2+ channels. J Neurosci 24:10980-10992.
11. 2. J Cell Biol 145:1219-1232.
12. Goldman-Rakic PS (1999) The physiological approach: functional architecture of working memory and disordered cognition in schizophrenia. Biol Psychiatry 46:650-661.
13. Haley JE, Delmas P, Offermanns S, Abogadie FC, Simon MI, Buckley NJ, Brown DA (2000) Muscarinic inhibition of calcium current and M current in Gαq-deficient mice. J Neurosci 20:3973-3979.
14. 1 receptor gene ablates muscarinic receptor-dependent M current regulation and seizure activity in mice. Proc Natl Acad Sci USA 94:13311-13316.
15. 1 subunits. J Cell Biol 123:949-962.
16. Hornfelt M, Edström A, Ekström PAR (1999) Upregulation of cytosolic phospholipase A2 correlates with apoptosis in mouse superior cervical and dorsal root ganglia neurons. Neurosci Lett 265:87-90.
17. Kanterman RY, Ma AL, Briley EM, Axelrod J, Felder CC (1990) Muscarinic receptors mediate the release of arachidonic acid from spinal cord and hippocampal neurons in primary culture. Neurosci Lett 118:235-237.
18. 2 activity. Biochem J 294:261-270.
19. Liao P, Yu D, Lu S, Tang Z, Liang MC, Zeng S, Lin W, Soong TW (2004) Smooth muscle-selective alternatively spliced exon generates functional variation in Cav1.2 calcium channels. J Biol Chem 279:50329-50335.
20. Lin LL, Lin AY, Knopf JL (1992) Cytosolic phospholipase A2 is coupled to hormonally regulated release of arachidonic acid. Proc Natl Acad Sci USA 89:6147-6151.
21. Lin LL, Wartmann M, Lin AY, Knopf JL, Seth A, Davis RJ (1993) cPLA2 is phosphorylated and activated by MAP kinase. Cell 72:269-278.
22. Lin Z, Harris C, Lipscombe D (1996) The molecular identity of Ca channel alpha 1-subunits expressed in rat sympathetic neurons. J Mol Neurosci 7:257-267.
23. Liu L, Rittenhouse AR (2000) Effects of arachidonic acid on unitary calcium currents in sympathetic neurons. J Physiol (Lond) 525:391-404.
24. 2+ current in sympathetic neurons. Proc Natl Acad Sci USA 100:295-300.
25. Liu L, Barrett CF, Rittenhouse AR (2001) Arachidonic acid both inhibits and enhances whole cell calcium currents in rat sympathetic neurons. Am J Physiol Cell Physiol 280:C1293-C1305.
26. 1 muscarinic inhibition of N-type calcium current in sympathetic neurons. Eur Biophys J 33:255-264.
27. Marshall J, Dolan BM, Garcia EP, Sathe S, Tang X, Mao Z, Blair LA (2003) Calcium channel and NMDA receptor activities differentially regulate nuclear C/EBPbeta levels to control neuronal survival. Neuron 39:625-639.
28. Martinez-Pinna J, Lamas JA, Gallego R (2002) Calcium current components in intact and dissociated adult mouse sympathetic neurons. Brain Res 951:227-236.
29. Mathie A, Bernheim L, Hille B (1992) Inhibition of N- and L-type calcium channels by muscarinic receptor activation in rat sympathetic neurons. Neuron 8:907-914.
30. Mechawar N, Cozzari C, Descarries L (2000) Cholinergic innervation in adult rat cerebral cortex: a quantitative immunocytochemical description. Comp Neurol 428:305-318.
31. Murakami M, Nakatani Y, Kuwata H, Kudo I (2000) Cellular components that functionally interact with signaling phospholipase A(2)s. Biochim Biophys Acta 1488:159-166.
32. Nakanishi S, Catt KJ, Balla T (1995) A wortmannin-sensitive phsophatidylinositol 4-kinase that regulates hormone-sensitive pools of inositol phospholipids. Proc Natl Acad Sci USA 92:5317-5321.
33. + channels by membrane lipids. Science 304:265-270.
34. Perez JF, Sanderson MJ (2005) The frequency of calcium oscillations induced by 5-HT, ACH and KCl determine the contraction of smooth muscle cells of intrapulmonary bronchioles. J Gen Physiol 125:535-553.
35. Petit-Jacques J, Hartzell HC (1996) Effect of arachidonic acid on the L-type calcium current in frog cardiac myocytes. J Physiol (Lond) 493:67-81.
36. Potier S, Psarropoulou C (2004) Modulation of muscarinic facilitation of epileptiform discharges in immature rat neocortex. Brain Res 997:194-206.
37. Rittenhouse AR, Zigmond RE (1999) Role of N- and L-type calcium channels in depolarization-induced activation of tyrosine hydroxylase and release of norepinephrine by sympathetic cell bodies and nerve terminals. J Neurobiol 40:137-148.
38. 1 receptors in DNA-transfected rodent neuroblastoma X glioma cells. J Physiol (Lond) 469:153-178.
39. 2 gating site. J Biol Chem 276:14855-14860.
40. 3 cells. J Biol Chem 276:38727-38737.
41. Sanderson MJ, Parker I (2003) Video-rate confocal microscopy. Methods Enzymol 360:447-481.
42. 2+ channels by using knockout mice. Proc Natl Acad Sci USA 96:10899-10904.
43. + channel activity in sympathetic neurons. Life Sci 68:2481-2487.
44. Spector AA (1975) Fatty acid binding to plasma albumin. J Lipid Res 16:165-179.
45. Suh BC, Hille B (2002) Recovery from muscarinic modulation of M current channels requires phosphatidylinositol 4,5-bisphosphate synthesis. Neuron 35:507-520.
46. Suh BC, Hille B (2005) Regulation of ion channels by phosphatidylinositol 4,5-bisphosphate. Curr Opin Neurobiol 15:370-378.
47. 1G. J Gen Physiol 124:225-238.
48. Villarroel A (1994) On the role of arachidonic acid in M-current modulation by muscarine in bullfrog sympathetic neurons. J Neurosci 14:7053-7066.
49. West AE, Griffith EC, Greenberg ME (2002) Regulation of transcription factors by neuronal activity. Nat Rev Neurosci 3:921-931.
50. 2. Nature 419:947-952.
51. Yu SP (1995) Roles of arachidonic acid, lipoxygenases and phosphatases in calcium-dependent modulation of M-current in bullfrog sympathetic neurons. J Physiol (Lond) 487:797-811.
52. 2 activates KCNQ channels, and its hydrolysis underlies receptor-mediated inhibition of M currents. Neuron 37:963-975.
53. Zhang Y, Cribbs LL, Satin J (2000) Arachidonic acid modulation of α1H, a cloned human T-type calcium channel. Am J Physiol Heart Circ Physiol 278:H184-H193.