The physiological approach: Functional architecture of working memory and disordered cognition in schizophrenia

Biological Psychiatry

Volumn 46, Issue 5, 1999, Pages 650-661

  Goldman Rakic, Patricia S ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Dopamine; Dopamine receptors; Nonhuman primates; Prefrontal cortex

Indexed keywords

DOPAMINE; DOPAMINE 1 RECEPTOR; DOPAMINE RECEPTOR;

COGNITION; CONFERENCE PAPER; HUMAN; PREFRONTAL CORTEX; PRIMATE; PRIORITY JOURNAL; SCHIZOPHRENIA; WORKING MEMORY;

ANIMALS; COGNITION DISORDERS; HUMANS; INTERNEURONS; MEMORY DISORDERS; NERVE NET; PREFRONTAL CORTEX; RECEPTORS, DOPAMINE; SCHIZOPHRENIA;

EID: 0032802830     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3223(99)00130-4     Document Type: Conference Paper

References (72)

1. Andreasen N.C., Rezai K., Alliger R., Swayze V.W. II, Flaum M., Kirchner P., et al. Hypofrontality in neuroleptic-naive patients and in patients with chronic schizophrenia. Arch Gen Psychiatry. 49:1992;943-958.
2. Baddeley A. Working Memory. 1986;Oxford University Press, London, England.
3. Baker S.C., Frith C.D., Frackowiak R.S.J., Dolan R.J. Active representation of shape and spatial location in man. Cereb Cortex. 6:1996;612-619.
4. Barbas H. Anatomic organization of basoventral and mediodorsal visual recipient prefrontal regions in the rhesus monkey. J Comp Neurol. 276:1988;313-342.
5. Benes F.M. The role of stress and dopamine-GABA interactions in the vulnerability for schizophrenia. J Psychiat Res. 31:1997;257-275.
6. Benes F.M., McSparren J., Bird E.D., SanGiovanni J.P., Vincent S.L. Deficits in small interneurons in prefrontal and cingulate cortices of schizophrenic and schizoaffective patients. Arch Gen Psychiatry. 48:1991;996-1001.
7. 5 dopamine receptor Studies in primate brain and transfected mammalian cells . Proc Natl Acad Sci USA. 92:1995;3468-3472.
8. Berman K.F., Zec R.F., Weinberger D.R. Physiologic dysfunction of dorsolateral prefrontal cortex in schizophrenia II. Role of neuroleptic treatment, attention, and mental effort . Arch Gen Psychiatry. 43:1986;126-135.
9. Bracewell R.M., Mazzoni P., Barash S., Andersen R.A. Motor intention activity in the macaque's lateral intraparietal area. II. Changes of motor plan. J Neurophysiol. 76:1996;1457-1464.
10. Brodmann K. Vergleichende localisationslehre der grosshirnrinde in ihren prinzipien dargestellt auf grund des zellenbaues. 1909;Barth, Leipzig, Germany.
11. Cavada C., Goldman-Rakic P.S. Posterior parietal cortex in rhesus monkey II. Evidence for segregated corticocortical networks linking sensory and limbic areas with the frontal lobe . J Comp Neurol. 287:1989;422-445.
12. Chafee M.V., Goldman-Rakic P.S. Matching patterns of activity in primate prefrontal area 8a and parietal area 7ip neurons during a spatial working memory task. J Neurophysiol. 79:1998;2919-2940.
13. Colby C.L., Duhamel J.R., Goldberg M.E. Visual, presaccadic and cognitive activation of single neurons in monkey lateral intraparietal area. J Neurophysiol. 76:1996;2841-2852.
14. Dolan R.J., Fletcher P.C. Dissociating prefrontal and hippocampal function in episodic memory encoding. Nature. 388:1997;582-585.
15. Fletcher P.C., Frith C.D., Grasby P.M., Friston K.J., Dolan R.J. Local and distributed effects of apomorphine on fronto-temporal function in acute unmedicated schizophrenia. J Neurosci. 16:1996;7055-7062.
16. Friedman H.R., Goldman-Rakic P.S. Coactivation of prefrontal cortex and inferior parietal cortex in working memory tasks revealed by 2DG functional mapping in the rhesus monkey. J Neurosci. 14:1994;2775-2788.
17. Friston K.J., Frith C.D. Schizophrenia A disconnection syndrome? Clin Neurosci. 3:1995;89-97.
18. Funahashi S., Bruce C.J., Goldman-Rakic P.S. Mnemonic coding of visual space in the monkey's dorsolateral prefrontal cortex. J Neurophysiol. 61:1989;1-19.
19. Garey L.J., Ong W.Y., Patel T.S., Kanani M., Davis A., Hornstein C., Bauer M. Reduction in dendritic spine number on cortical pyramidal neurons in schizophrenia. Soc Neurosci Abstr. 21:1995;237.
20. Glantz L.A., Lewis D.A. Assessment of spine density on layer III pyramidal cells in the prefrontal cortex of schizophrenic subjects. Soc Neurosci Abstr. 21:1995;239.
21. Gnadt J.W., Andersen R.A. Memory related motor planning activity in posterior parietal cortex of macaque. Exp Brain Res. 70:1988;216-220.
22. Gold J.M., Berman K.F., Moore E., Weinberger D.R. PET validation and clinical application of a novel prefrontal task. Neuropsychology. 10:1996;3-10.
23. 15O-labeled water regional cerebral blood flow study in normal humans . Neuroimage. 3:1996;69-78.
24. Goldman P.S., Nauta W.J.H. Columnar distribution of cortico-cortical fibers in the frontal association, limbic, and motor cortex of the developing rhesus monkey. Brain Res. 122:1977;393-413.
25. Goldman-Rakic P.S. Circuitry of primate prefrontal cortex and regulation of behavior by representational memory. Plum F. Handbook of Physiology, The Nervous System, Higher Functions of the Brain. 1987;373-417 American Physiological Society, Bethesda, MD.
26. Goldman-Rakic P.S., Leranth C., Williams S.M., Mons N., Geffard M. Dopamine synaptic complex with pyramidal neurons in primate cerebral cortex. Proc Natl Acad Sci USA. 86:1989;9015-9019.
27. Gross C.G., Rocha-Miranda C.E., Bender D.B. Visual properties of neurons in inferotemporal cortex of the Macaque. J Neurophysiol. 35:1972;96-111.
28. Kawaguchi Y. Physiological subgroups of nonpyramidal cells with specific morphological characteristics in layer II/III of rat frontal cortex. J Neuroscience. 15:1995;2638-2655.
29. 2 short isoform in dopaminergic pathways. Proc Natl Acad Sci USA. 95:1998;7731-7736.
30. 2 dopamine receptors in brain with subtype-specific antibodies. Proc Natl Acad Sci USA. 90:1993;8861-8865.
31. 4 dopamine receptor mRNAs in the primate cerebral cortex vs. neostriatum Effects of chronic treatment with typical and atypical antipsychotic drugs . J Pharmacol Exp Ther. 283:1997;939-946.
32. Mazzoni P., Bracewell R.M., Barash S., Andersen R.A. Motor intention activity in the macaque's lateral intraparietal area. I. Dissociation of motor plan from sensory memory. J Neurophysiol. 76:1996;1439-1456.
33. McCarthy G., Blamire A.M., Puce A., Nobre A.C., Bloch G., Hyder F., et al. Functional magnetic resonance imaging of human prefrontal cortex activation during a spatial working memory task. Proc Natl Acad Sci USA. 91:1994;8690-8694.
34. McCarthy G., Puce A., Constable R.T., Krystal J.H., Gore J.C., Goldman-Rakic P.S. Activation of human prefrontal cortex during spatial and object working memory tasks measured by functional MRI. Cereb Cortex. 6:1996;600-611.
35. McCormick D.A., Prince D.A. Two types of muscarinic response to acetylcholine in mammalian cortical neurons. Proc Natl Acad Sci USA. 82:1985;6344-6348.
36. Mishkin M., Manning F.J. Non-spatial memory after selective prefrontal lesions in monkeys. Brain Res. 143:1978;313-323.
37. 4 receptors in GABAergic neurons of the primate brain. Nature. 381:1996;245-248.
38. 1 receptor in interneurons of macaque prefrontal cortex Distribution and subcellular localization . J Neurosci. 18:1998;10553-10565.
39. 1 receptors in schizophrenia revealed by PET. Nature. 385:1997;634-636.
40. Olney J.W., Farber N.B. Glutamate receptor dysfunction and schizophrenia. Arch Gen Psychiatry. 52:1995;998-1007.
41. Ó Scalaidhe S.P., Wilson F.A.W., Goldman-Rakic P.S. Areal segregation of face-processing neurons in prefrontal cortex. Science. 278:1997;1135-1138.
42. Park S., Holzman P.S. Schizophrenics show spatial working memory deficits. Arch Gen Psychiatry. 49:1992;975-982.
43. Park S., Holzman P.S. Association of working memory deficit and eye tracking dysfunction in schizophrenia. Schizophr Res. 11:1993;55-61.
44. Passingham R.E. Delayed matching after selective prefrontal lesions in monkeys (Macac mulatta). Brain Res. 92:1975;89-102.
45. Petrides M., Pandya D.N. Projections to the frontal cortex from the posterior parietal region in the rhesus monkey. J Comp Neurol. 228:1984;105-116.
46. Rajkowska G., Selemon L.D., Goldman-Rakic P.S. Neuronal and glial somal size in the prefrontal cortex A post-mortem study of schizophrenia and Huntington's disease . Arch Gen Psychiatry. 55:1998;215-224.
47. Rao S.G., Williams G.V., Goldman-Rakic P.S. Isodirectional tuning of adjacent interneurons and pyramidal cells during working memory Evidence for microcolumnar organization in PFC . J Neurophysiol. 81:1999;1903-1916.
48. Rolls E.T., Baylis G.C. Size and contrast have only small effects on the responses to faces of neurons in the cortex of the superior temporal sulcus of the monkey. Exp Brain Res. 65:1986;38-48.
49. Sarkissov S.A., Filimonoff I.N., Kononova I.P., Preobrazenskaja N.S., Kukueva L.A. Atlas of the Cytoarchitectonics of the Human Cerebral Cortex [in Russian]. 1955;Medgiz, Moscov.
50. 1 dopamine receptors in prefrontal cortex Involvement in working memory . Science. 251:1991;947-950.
51. Saykin A.J., Gur R.C., Gur R.E., Mozley P.D., Mozley L.H., Resnick S.M., et al. Neuropsychological function in schizophrenia Selective impairment in memory and learning . Arch Gen Psychiatry. 48:1991;618-624.
52. Schooler C., Neumann E., Caplan L.J., Roberts B.R. A time course analysis of Stroop interference and facilitation Comparing normal individuals and individuals with schizophrenia . J Exp Psychol Gen. 126:1997;19-36.
53. Schwartz M.L., Goldman-Rakic P.S. Callosal and intrahemispheric connectivity of the prefrontal association cortex in rhesus monkey Relation between intraparietal and principal sulcal cortex . J Comp Neurol. 226:1984;403-420.
54. Selemon L.D., Rajkowska G., Goldman-Rakic P.S. Elevated neuronal density in prefrontal area 46 in brains from schizophrenic patients application of a 3-dimensional, stereologic counting method . J Comp Neurol. 392:1998;402-412.
55. Selemon L.D., Rajkowska G., Goldman-Rakic P.S. Abnormally high neuronal density in the schizophrenic cortex A morphometric analysis of prefrontal area 9 and occipital area 17 . Arch Gen Psychiatry. 52:1995;805-818.
56. Selemon L.D., Goldman-Rakic P.S. Longitudinal topography and interdigitation of corticostriatal projections in the rhesus monkey. J Neurosci. 5:1985;776-794.
57. Selemon L.D., Goldman-Rakic P.S. Common cortical and subcortical target areas of the dorsolateral prefrontal and posterior parietal cortices in the rhesus monkey Evidence for a distributed neural network subserving spatially guided behavior . J Neurosci. 8:1998;4049-4068.
58. Sereno A.B., Holzman P.S. Antisaccades and smooth pursuit eye movements in schizophrenia. J Biol Psychiatry. 37:1995;394-401.
59. Shallice T. Specific impairments in planning. Philos Trans R Soc London. 298:1982;199-209.
60. 1 dopamine receptor immunoreactivity in human and monkey cerebral cortex Predominant and extrasynaptic localization in dendritic spines . Proc Natl Acad Sci USA. 91:1994;5720-5724.
61. Smith E.E., Jonides J., Koeppe R.A. Dissociating verbal and spatial working memory. Cereb Cortex. 6:1996;11-20.
62. Stanton G.B., Bruce C.J., Goldberg M.E. Topography of projections to posterior cortical areas from the macaque frontal eye fields. J Comp Neurol. 353:1995;291-305.
63. Stevens A.A., Goldman-Rakic P.S., Gore J.C., Fulbright R.K., Wexler B.E. Cortical dysfunction in schizophrenia during auditory working memory revealed by functional MRI. Arch Gen Psychiatry. 55:1998;1097-1103.
64. Suzuki H., Azuma M. Topographic studies on visual neurons in the dorsolateral prefrontal cortex of the monkey. Exp Brain Res. 53:1983;47-58.
65. Sweeney J.A., Mintun M.A., Kwee B.S., Wiseman M.B., Brown D.L., Rosenberg D.R., et al. Positron emission tomography study of voluntary saccadic eye movements and spatial working memory. J Neurophysiol. 75:1996;454-468.
66. Ungerleider L.G., Mishkin M. Two cortical visual systems. Ingle D.J., Goodale M.A., Maunsfield R.J.W. Analysis of Visual Behavior. 1982;549-586 MIT Press, Cambridge, MA.
67. Weinberger D.R., Berman K.F., Zec R.F. Physiological dysfunction of dorsolateral prefrontal cortex in schizophrenia I. Regional cerebral blood flow (rCBF) evidence . Arch Gen Psychiatry. 43:1996;114-125.
68. Weinberger D.R., Berman K.F., Suddath R., Torrey E.F. Evidence of dysfunction of a prefrontal-limbic network in schizophrenia A magnetic resonance imaging and regional cerebral blood flow study of discordant monozygotic twins . Am J Psychiatry. 149:1992;890-897.
69. Wexler B.E., Stevens A.A., Bowers A.A., Sernyak M.J., Goldman-Rakic P.S. Word and tone working memory deficits in schizophrenia. Arch Gen Psychiatry. 55:1998;1093-1096.
70. 1 receptors in prefrontal cortex. Nature. 376:1995;572-575.
71. Wilson F.A.W., Ó Scalaidhe S.P., Goldman-Rakic P.S. Functional synergism between putative γ-aminobutyrate-containing neurons and pyramidal neurons in prefrontal cortex. Proc Natl Acad Sci USA. 91:1994;4009-4013.
72. Wilson F.A.W., Ó Scalaidhe S.P., Goldman-Rakic P.S. Dissociation of object and spatial processing domains in primate prefrontal cortex. Science. 260:1993;1955-1958.