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Volumn 13, Issue 3, 2006, Pages 863-873

Combination therapy for treating breast cancer using antiestrogen, ERA-923, and the mammalian target of rapamycin inhibitor, temsirolimus

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYTAMOXIFEN; ANTIESTROGEN; ESTROGEN RECEPTOR ALPHA; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; PIPENDOXIFENE; RALOXIFENE; TEMSIROLIMUS;

EID: 33751117795     PISSN: 13510088     EISSN: None     Source Type: Journal    
DOI: 10.1677/erc.1.01170     Document Type: Article
Times cited : (35)

References (44)
  • 1
    • 33751116789 scopus 로고    scopus 로고
    • (accessed Feb. 2006)
    • American Cancer Society http://www.cancer.org (accessed Feb. 2006).
  • 3
    • 24744465206 scopus 로고    scopus 로고
    • The farnesyl transferase inhibitor (FTI) SCH66336 (lonafarnib) inhibits Rheb farnesylation and mTOR signaling. Role in FTI enhancement of taxane and tamoxifen anti-tumor activity
    • Basso AD, Mirza A, Liu G, Long BJ, Bishop WR & Kirschmeier P 2005 The farnesyl transferase inhibitor (FTI) SCH66336 (lonafarnib) inhibits Rheb farnesylation and mTOR signaling. Role in FTI enhancement of taxane and tamoxifen anti-tumor activity. Journal of Biological Chemistry 280 31101-31108.
    • (2005) Journal of Biological Chemistry , vol.280 , pp. 31101-31108
    • Basso, A.D.1    Mirza, A.2    Liu, G.3    Long, B.J.4    Bishop, W.R.5    Kirschmeier, P.6
  • 4
    • 0034955343 scopus 로고    scopus 로고
    • A systematic overview of chemotherapy effects in breast cancer
    • SBU-group
    • Bergh J, Jonsson PE, Glimelius B, Nygren P; SBU-group 2001 A systematic overview of chemotherapy effects in breast cancer. Acta Oncologica 40 253-281.
    • (2001) Acta Oncologica , vol.40 , pp. 253-281
    • Bergh, J.1    Jonsson, P.E.2    Glimelius, B.3    Nygren, P.4
  • 6
    • 4544315354 scopus 로고    scopus 로고
    • New targets for therapy in breast cancer: Mammalian target of rapamycin (mTOR) antagonists
    • Carraway H & Hidalgo M 2004 New targets for therapy in breast cancer: mammalian target of rapamycin (mTOR) antagonists. Breast Cancer Research 6 219-224.
    • (2004) Breast Cancer Research , vol.6 , pp. 219-224
    • Carraway, H.1    Hidalgo, M.2
  • 8
    • 0036817880 scopus 로고    scopus 로고
    • Clinical development of mammalian target of rapamycin inhibitors
    • Dancey JE 2002 Clinical development of mammalian target of rapamycin inhibitors. Hematology-Oncology Clinics of North America 16 1101-1114.
    • (2002) Hematology-Oncology Clinics of North America , vol.16 , pp. 1101-1114
    • Dancey, J.E.1
  • 11
    • 2342584022 scopus 로고    scopus 로고
    • Mammalian target of rapamycin (mTOR) inhibitors
    • Dutcher JP 2004 Mammalian target of rapamycin (mTOR) inhibitors. Current Oncology Reports 6 111-115.
    • (2004) Current Oncology Reports , vol.6 , pp. 111-115
    • Dutcher, J.P.1
  • 13
    • 2342545519 scopus 로고    scopus 로고
    • Target of rapamycin (TOR): An integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression
    • Fingar DC & Blenis J 2004 Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression. Oncogene 23 3151-3171.
    • (2004) Oncogene , vol.23 , pp. 3151-3171
    • Fingar, D.C.1    Blenis, J.2
  • 17
    • 18144405740 scopus 로고    scopus 로고
    • Estrogen receptor alpha and beta subtype expression and transactivation capacity are differentially affected by receptor-, hsp90- and immunophilin-ligands in human breast cancer cells
    • Gougelet A, Boucher C, Marsaud W, Maillard S, Mueller SO, Korach KS & Renoir JM 2005 Estrogen receptor alpha and beta subtype expression and transactivation capacity are differentially affected by receptor-, hsp90- and immunophilin-ligands in human breast cancer cells. Journal of Steroid Biochemistry Molecular Biology 94 71-81.
    • (2005) Journal of Steroid Biochemistry Molecular Biology , vol.94 , pp. 71-81
    • Gougelet, A.1    Boucher, C.2    Marsaud, W.3    Maillard, S.4    Mueller, S.O.5    Korach, K.S.6    Renoir, J.M.7
  • 18
    • 0034787326 scopus 로고    scopus 로고
    • A new antiestrogen, 2-(4-hydroxy-phenyl)-3-methyl-1-[4-(2-piperidin-1-yl- ethoxy)-benzyl]-1H-indol-5-ol hydrochloride (ERA-923), inhibits the growth of tamoxifen-sensitive and -resistant tumors and is devoid of uterotropic effects in mice and rats
    • Greenberger LM, Annable T, Collins KI, Komm BS, Lyttle CR, Miller CP, Satyaswaroop PG, Zhang Y & Frost P 2001 A new antiestrogen, 2-(4-hydroxy-phenyl)-3-methyl-1-[4-(2-piperidin-1-yl-ethoxy)-benzyl] -1H-indol-5-ol hydrochloride (ERA-923), inhibits the growth of tamoxifen-sensitive and -resistant tumors and is devoid of uterotropic effects in mice and rats. Clinical Cancer Research 7 3166-3177.
    • (2001) Clinical Cancer Research , vol.7 , pp. 3166-3177
    • Greenberger, L.M.1    Annable, T.2    Collins, K.I.3    Komm, B.S.4    Lyttle, C.R.5    Miller, C.P.6    Satyaswaroop, P.G.7    Zhang, Y.8    Frost, P.9
  • 20
    • 0027282697 scopus 로고
    • Mechanisms of hormone resistance in breast cancer
    • Horwitz KB 1993 Mechanisms of hormone resistance in breast cancer. Breast Cancer Research and Treatment 26 119-130.
    • (1993) Breast Cancer Research and Treatment , vol.26 , pp. 119-130
    • Horwitz, K.B.1
  • 22
    • 0031081367 scopus 로고    scopus 로고
    • Modeling the interaction between FK506 and FKBP12: A mechanism for formation of the calcineurin inhibitory complex
    • Ivery MT & Weiler L 1997 Modeling the interaction between FK506 and FKBP12: a mechanism for formation of the calcineurin inhibitory complex. Bioorganic and Medicinal Chemistry 5 217-232.
    • (1997) Bioorganic and Medicinal Chemistry , vol.5 , pp. 217-232
    • Ivery, M.T.1    Weiler, L.2
  • 24
    • 0036695680 scopus 로고    scopus 로고
    • Highlights from the 38th annual meeting of the American Society of Clinical Oncology
    • Johnson L, Gibson A, Maung K & O'Shaughnessy J 2002 Highlights from the 38th annual meeting of the American Society of Clinical Oncology. Clinical Breast Cancer 3 174-179.
    • (2002) Clinical Breast Cancer , vol.3 , pp. 174-179
    • Johnson, L.1    Gibson, A.2    Maung, K.3    O'Shaughnessy, J.4
  • 25
    • 12144255062 scopus 로고    scopus 로고
    • Combinations of endocrine and biological agents: Present status of therapeutic and presurgical investigations
    • Johnston SRD 2005 Combinations of endocrine and biological agents: present status of therapeutic and presurgical investigations. Clinical Cancer Research 11 889S-899S.
    • (2005) Clinical Cancer Research , vol.11
    • Johnston, S.R.D.1
  • 27
    • 0030670754 scopus 로고    scopus 로고
    • A review of endocrine options for the treatment of advanced breast cancer
    • Kaufmann M 1997 A review of endocrine options for the treatment of advanced breast cancer. Oncology 54 2-5.
    • (1997) Oncology , vol.54 , pp. 2-5
    • Kaufmann, M.1
  • 28
    • 0035511744 scopus 로고    scopus 로고
    • A pitfall in the survival benefit of adjuvant chemotherapy for node- and hormone receptor-positive patients with breast cancer: The paradoxical role of Bcl-2 oncoprotein
    • Kim R, Osaki A & Toge T 2001 A pitfall in the survival benefit of adjuvant chemotherapy for node- and hormone receptor-positive patients with breast cancer: the paradoxical role of Bcl-2 oncoprotein. International Journal of Oncology 19 1075-1080.
    • (2001) International Journal of Oncology , vol.19 , pp. 1075-1080
    • Kim, R.1    Osaki, A.2    Toge, T.3
  • 29
    • 0033651439 scopus 로고    scopus 로고
    • MEKK1 activation of human estrogen receptor alpha and stimulation of the agonistic activity of 4-hydroxytamoxifen in endometrial and ovarian cancer cells
    • Lee H, Jiang F, Wang Q, Nicosia SV, Yang J, Su B & Bai W 2000 MEKK1 activation of human estrogen receptor alpha and stimulation of the agonistic activity of 4-hydroxytamoxifen in endometrial and ovarian cancer cells. Molecular Endocrinology 14 1882-1896.
    • (2000) Molecular Endocrinology , vol.14 , pp. 1882-1896
    • Lee, H.1    Jiang, F.2    Wang, Q.3    Nicosia, S.V.4    Yang, J.5    Su, B.6    Bai, W.7
  • 30
    • 0035683554 scopus 로고    scopus 로고
    • Nuclear receptors, coregulators, ligands, and selective receptor modulators: Making sense of the patchwork quilt
    • McKenna NJ & O'Malley BW 2001 Nuclear receptors, coregulators, ligands, and selective receptor modulators: making sense of the patchwork quilt. Annals of the New York Academy of Sciences 949 3-5.
    • (2001) Annals of the New York Academy of Sciences , vol.949 , pp. 3-5
    • McKenna, N.J.1    O'Malley, B.W.2
  • 31
    • 0042232592 scopus 로고    scopus 로고
    • Enhanced estrogen receptor (ER) alpha, ERBB2, and MAPK signal transduction pathways operate during the adaptation of MCF-7 cells to long term estrogen deprivation
    • Martin LA, Farmer I, Johnston SRD, Ali S, Marshall C & Dowsett M 2003 Enhanced estrogen receptor (ER) alpha, ERBB2, and MAPK signal transduction pathways operate during the adaptation of MCF-7 cells to long term estrogen deprivation. Journal of Biochemical Chemistry 278 30458-30468.
    • (2003) Journal of Biochemical Chemistry , vol.278 , pp. 30458-30468
    • Martin, L.A.1    Farmer, I.2    Johnston, S.R.D.3    Ali, S.4    Marshall, C.5    Dowsett, M.6
  • 34
    • 0034820022 scopus 로고    scopus 로고
    • Cell cycle regulation in the G1 phase: A promising target for the development of new chemotherapeutic anticancer agents
    • Owa T, Yoshino H, Yoshimatsu K & Nagasu T 2001 Cell cycle regulation in the G1 phase: a promising target for the development of new chemotherapeutic anticancer agents. Current Medicinal Chemistry 8 1487-1503.
    • (2001) Current Medicinal Chemistry , vol.8 , pp. 1487-1503
    • Owa, T.1    Yoshino, H.2    Yoshimatsu, K.3    Nagasu, T.4
  • 35
    • 0024993530 scopus 로고
    • A three-dimensional model to analyze drug-drug interactions
    • Prichard MN & Shipman CJ 1990 A three-dimensional model to analyze drug-drug interactions. Antiviral Research 14 181-206.
    • (1990) Antiviral Research , vol.14 , pp. 181-206
    • Prichard, M.N.1    Shipman, C.J.2
  • 36
    • 0038688097 scopus 로고    scopus 로고
    • Phase I and pharmacokinetic study of CCI-779, a novel cytostatic cell-cycle inhibitor, in combination with 5-fluorouracil and leucovorin in patients with advanced solid tumors
    • Punt CJ, Boni J, Bruntsch U, Peters M & Thielert C 2003 Phase I and pharmacokinetic study of CCI-779, a novel cytostatic cell-cycle inhibitor, in combination with 5-fluorouracil and leucovorin in patients with advanced solid tumors. Annals of Oncology 14 931-937.
    • (2003) Annals of Oncology , vol.14 , pp. 931-937
    • Punt, C.J.1    Boni, J.2    Bruntsch, U.3    Peters, M.4    Thielert, C.5
  • 37
    • 0036286677 scopus 로고    scopus 로고
    • Human estrogen receptor-alpha: Regulation by synthesis, modification and degradation
    • Reid G, Denger S, Kos M & Gannon F 2002 Human estrogen receptor-alpha: regulation by synthesis, modification and degradation. Cellular and Molecular Life Sciences 59 821-831.
    • (2002) Cellular and Molecular Life Sciences , vol.59 , pp. 821-831
    • Reid, G.1    Denger, S.2    Kos, M.3    Gannon, F.4
  • 38
  • 40
    • 0034099605 scopus 로고    scopus 로고
    • Current and potential chemotherapeutic agents used for induction chemotherapy in the treatment of breast cancer
    • Smith IC, Hutcheon AW & Keys SD 2000 Current and potential chemotherapeutic agents used for induction chemotherapy in the treatment of breast cancer. Current Pharmaceutical Design 6 327-343.
    • (2000) Current Pharmaceutical Design , vol.6 , pp. 327-343
    • Smith, I.C.1    Hutcheon, A.W.2    Keys, S.D.3
  • 41
    • 18044384874 scopus 로고    scopus 로고
    • Society AC. Atlanta: American Cancer Society
    • Society AC Cancer Facts and Figures 2005 Atlanta: American Cancer Society;2005.
    • (2005) Cancer Facts and Figures 2005
  • 42
    • 0034764605 scopus 로고    scopus 로고
    • PI 3-kinase, mTOR, protein synthesis and cancer
    • Vogt PK 2001 PI 3-kinase, mTOR, protein synthesis and cancer. Trends in Molecular Medicine 7 482-484.
    • (2001) Trends in Molecular Medicine , vol.7 , pp. 482-484
    • Vogt, P.K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.