Carcinogenicity classification of vanadium pentoxide and inorganic vanadium compounds, the NTP study of carcinogenicity of inhaled vanadium pentoxide, and vanadium chemistry

Regulatory Toxicology and Pharmacology

Volumn 47, Issue 1, 2007, Pages 110-114

  Duffus, John H ^a  

^a Edinburgh Centre for Toxicology   (United Kingdom)

Author keywords

Carcinogenicity; Metals; Nanoparticles; Reactive oxygen; Speciation; Test methods; Toxicity classification; Vanadium

Indexed keywords

CARCINOGEN; INORGANIC COMPOUND; ORGANIC COMPOUND; OXYGEN; VANADIUM; VANADIUM DERIVATIVE; VANADIUM PENTOXIDE;

AEROSOL; ARTICLE; CARCINOGENICITY; CLASSIFICATION; CRYSTAL; ENVIRONMENTAL EXPOSURE; HUMAN; INHALATION; NANOPARTICLE; NONHUMAN; PARTICULATE MATTER; PHYSICAL CHEMISTRY; PHYSICAL PARAMETERS; PRIORITY JOURNAL; TOXICITY; TOXICOLOGY; UNITED STATES;

AEROSOLS; ANIMALS; CARCINOGENICITY TESTS; CARCINOGENS; HUMANS; INHALATION EXPOSURE; METAL NANOPARTICLES; PARTICLE SIZE; REACTIVE OXYGEN SPECIES; VANADIUM COMPOUNDS;

EID: 33751114704     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2006.08.006     Document Type: Article

References (15)

1. Baran E.J. Model studies related to vanadium biochemistry: recent advances and perspectives. J. Braz. Chem. Soc. 14 (2003) 878-888
2. Brown D.M., Stone V., Findlay P., MacNee W., and Donaldson K. Increased inflammations and intracellular calcium caused by ultrafine carbon black is independent of transition metals or other soluble components. Occup. Environ. Med. 57 (2000) 685-691
3. Brown D.M., Wilson M.R., Stone V., Findlay P., MacNee W., and Donaldson K. Size-dependent proinflammatory effects of ultrafine polystyrene particles: a role for surface area and oxidative stress in the enhanced activity of ultrafines. Toxicol. Appl. Pharmacol. 175 (2001) 191-199
4. De Flora S. Threshold mechanisms and site specificity in chromium(VI) carcinogenesis. Carcinogenesis 21 (2000) 533-541
5. Deutsche Forschungsgemeinschaft, 2005. Press Release No. 46, 19 July 2005. .
6. Dick C.A., Brown D.M., Donaldson K., and Stone V. The role of free radicals in the toxic and inflammatory effects of four different ultrafine particle types. Inhal. Toxicol. 15 (2003) 39-52
7. Greenwood N.N., and Earnshaw A. Chemistry of the Elements. second ed. (1997), Pub. Butterworth-Heinemann, Oxford
8. Hussain S.P., Hofseth L.J., and Harris C.C. Radical causes of cancer. Nat. Rev. Cancer 3 (2003) 276-285
9. IARC Monographs Evaluating Carcinogenic Risks to Humans, 2006. vol. 86, Cobalt in Hard-metals and Cobalt Sulfate, Gallium Arsenide, Indium Phosphide and Vanadium Pentoxide. International Agency for Research on Cancer, Lyon.
10. Li X.Y., Gilmour P.S., Donaldson K., and MacNee W. Free radical and pro-inflammatory activity of particulate air pollution (PM10) in vivo and in vitro. Thorax 51 (1996) 1216-1222
11. National Toxicology Program (NTP), 2002. Toxicology and Carcinogenesis Studies of Vanadium Pentoxide (CAS No. 1314-62-1) in F344/N Rats and B6C3F1 Mice (Inhalation Studies)-NTP-TR507. Pub. DHHS, NIH, NCI & NIEHS, Research Triangle Park, NC.
12. Nel A., Xia T., Mädler L., and Li N. Toxic potential of materials at the nanolevel. Science 311 (2006) 622-627
13. Ress N.B., Chou B.J., Renne R.A., Dill J.A., Miller R.A., Roycroft R.A., Hailey J.R., Haseman J.K., and Bucher J.R. Carcinogenicity of inhaled vanadium pentoxide in F344/N Rats and B6C3F1 mice. Toxicol. Sci. 74 (2003) 287-296
14. Valko M., Rhodes C.J., Moncola J., Izakovic M., and Mazura M. Free radicals, metals and antioxidants in oxidative stress-induced cancer. Chem. Biol. Interact. 160 (2006) 1-40
15. World Health Organization (WHO), 2001. Vanadium pentoxide and other inorganic vanadium compounds. Concise International Chemical Assessment Documents Document 29. WHO, Geneva.