-
1
-
-
0034779291
-
The EGFR as a target for anticancer therapy - Focus on cetuximab
-
Baselg J.: The EGFR as a target for anticancer therapy - focus on cetuximab. Eur J Cancer 2001; 37, Suppl 4: 16-22.
-
(2001)
Eur J Cancer
, vol.37
, Issue.SUPPL. 4
, pp. 16-22
-
-
Baselg, J.1
-
2
-
-
17844390172
-
Epidermal growth factor receptor mutations, small-molecule kinase inhibitors, and non-small-cell lung cancer: Current knowledge and future directions
-
Pao W., Miller V.: Epidermal growth factor receptor mutations, Small-molecule kinase inhibitors, and Non-small-cell lung cancer: Current knowledge and future directions. J Clin Oncol, 2005; 23: 2556-2568.
-
(2005)
J Clin Oncol
, vol.23
, pp. 2556-2568
-
-
Pao, W.1
Miller, V.2
-
3
-
-
1842471336
-
Signaling through the epidermal growth factor receptor during the development of malignancy
-
Grandis JR., Sok JC.: Signaling through the epidermal growth factor receptor during the development of malignancy. Pharmacol Ther 2004; 102: 37-46.
-
(2004)
Pharmacol Ther
, vol.102
, pp. 37-46
-
-
Grandis, J.R.1
Sok, J.C.2
-
4
-
-
13544256790
-
The ErbB/Her receptor protein-tyrosine kinase and cancer
-
Roskoski R.: The ErbB/Her receptor protein-tyrosine kinase and cancer. Biochem Biophys Res Commun 2004; 319: 1155-1164.
-
(2004)
Biochem Biophys Res Commun
, vol.319
, pp. 1155-1164
-
-
Roskoski, R.1
-
5
-
-
0001744237
-
Retinoic acid normalizes the increased gene transcriptiono rate of TGF-alpha and EGFR in head and neck cancer cell lines
-
Grandis JR., Zeng O., Tweardy DJ.: Retinoic acid normalizes the increased gene transcriptiono rate of TGF-alpha and EGFR in head and neck cancer cell lines. Nat Med 1996; 2: 237-240.
-
(1996)
Nat Med
, vol.2
, pp. 237-240
-
-
Grandis, J.R.1
Zeng, O.2
Tweardy, D.J.3
-
6
-
-
33751076293
-
Amplifikace genu Her-2/neu: Molekulární, buněčné a klinické aspekty
-
Trojanec R., Špačková K., Cwiertka K. et al.: Amplifikace genu Her-2/neu: molekulární, buněč né a klinické aspekty. Klin Farmakol Farmac 2002; 16: 23-29.
-
(2002)
Klin Farmakol Farmac
, vol.16
, pp. 23-29
-
-
Trojanec, R.1
Špačková, K.2
Cwiertka, K.3
-
7
-
-
2342471392
-
Activating mutations' in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
Lynch TJ., Bell DW., Sordella R. et al.: Activating mutations' in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med, 2004; 350: 2129-2139.
-
(2004)
N Engl J Med
, vol.350
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
-
8
-
-
20044364940
-
Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers
-
Shigematsu H., Lin L., Takahashi T. et al.: Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers. J Natl Cancer Inst, 2005; 97: 339-328.
-
(2005)
J Natl Cancer Inst
, vol.97
, pp. 339-1328
-
-
Shigematsu, H.1
Lin, L.2
Takahashi, T.3
-
9
-
-
10844231985
-
Mutation of the epidermal growth factor receptor gene in lung cancer: Biological and clinical implications
-
Kosaka T., Yatabe Y., Endoh H. et al.: Mutation of the epidermal growth factor receptor gene in lung cancer: Biological and clinical implications. Cancer Res, 2004; 64: 8919-8923.
-
(2004)
Cancer Res
, vol.64
, pp. 8919-8923
-
-
Kosaka, T.1
Yatabe, Y.2
Endoh, H.3
-
10
-
-
20144387591
-
Mutations in th tyrosine kinase domain of the epidermal growth factor receptor in non-small cell lung cancer
-
Yang SH., Mechanic LE., Yant P. et al.: Mutations in th tyrosine kinase domain of the epidermal growth factor receptor in non-small cell lung cancer. Clin Cancer Res, 2005; 11: 2106-2110.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 2106-2110
-
-
Yang, S.H.1
Mechanic, L.E.2
Yant, P.3
-
11
-
-
0029815093
-
Enhanced tumorigenic behavior of glioblastoma cells expressing a truncated epidermal growth factor receptor is mediated through the Ras-Shc-Grb2 pathway
-
Prigent SA., Nagane M., Mishima K. et al.: Enhanced tumorigenic behavior of glioblastoma cells expressing a truncated epidermal growth factor receptor is mediated through the Ras- Shc-Grb2 pathway. J Biol Chem 1996; 271: 25639-25645.
-
(1996)
J Biol Chem
, vol.271
, pp. 25639-25645
-
-
Prigent, S.A.1
Nagane, M.2
Mishima, K.3
-
12
-
-
0020933452
-
Biological effects in vitro of monoclonal antibodies tu human epidermal growth factor receptors
-
Sato JD., Kawamoto T., Le AD. et al.: Biological effects in vitro of monoclonal antibodies tu human epidermal growth factor receptors. Mol Biol Med 1983; 1: 511-529.
-
(1983)
Mol Biol Med
, vol.1
, pp. 511-529
-
-
Sato, J.D.1
Kawamoto, T.2
Le, A.D.3
-
13
-
-
18444398046
-
Targeted therapies in the treatment of colorectal cancers
-
Alekshun T., Garrett Ch.: Targeted therapies in the treatment of colorectal cancers. Cancer Control 2005; 12: 105-110.
-
(2005)
Cancer Control
, vol.12
, pp. 105-110
-
-
Alekshun, T.1
Garrett, Ch.2
-
14
-
-
4444344330
-
EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitineb and erlotinib
-
Pao W., Miller V., Zakowski M. et al: EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitineb and erlotinib. PNAS 2004; 101: 13306-13311.
-
(2004)
PNAS
, vol.101
, pp. 13306-13311
-
-
Pao, W.1
Miller, V.2
Zakowski, M.3
-
15
-
-
27544479318
-
Role of tyrosine kinase inhibitors in cancer therapy
-
Arora A., Scholar EM.: Role of tyrosine kinase inhibitors in cancer therapy. J Pharmacol Exp Ther, 2005; 315: 971-979.
-
(2005)
J Pharmacol Exp Ther
, vol.315
, pp. 971-979
-
-
Arora, A.1
Scholar, E.M.2
-
16
-
-
0033987746
-
Lessons learned from the development of an Abl tyrosine kinase inhibitor for chronic myelogenous leukemia
-
Druker BJ., Lydon NB.: Lessons learned from the development of an Abl tyrosine kinase inhibitor for chronic myelogenous leukemia, J Clin Invest, 2000; 105: 3-7.
-
(2000)
J Clin Invest
, vol.105
, pp. 3-7
-
-
Druker, B.J.1
Lydon, N.B.2
-
17
-
-
0035800507
-
Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification
-
Gorre ME., Mohammed M., Ellwood K. et al.: Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification. Science, 2001; 293: 876-880.
-
(2001)
Science
, vol.293
, pp. 876-880
-
-
Gorre, M.E.1
Mohammed, M.2
Ellwood, K.3
-
18
-
-
14744274624
-
Comparative analysis of two clinically active BCR-ABL kinase inhibitors reveals the role of conformation-specific binding in resistance
-
Burgess MR., Skaggs BJ., Shah NP., Lee FY., Sawyers CL.: Comparative analysis of two clinically active BCR-ABL kinase inhibitors reveals the role of conformation-specific binding in resistance. PNAS, 2005; 102: 3395-3400.
-
(2005)
PNAS
, vol.102
, pp. 3395-3400
-
-
Burgess, M.R.1
Skaggs, B.J.2
Shah, N.P.3
Lee, F.Y.4
Sawyers, C.L.5
-
19
-
-
13844261144
-
A non-ATP-competitive inhibitor of BCR-ABL overrides imatinib resistance
-
Gumireddy K., Baker SJ., Cosenza SC. et al: A non-ATP-competitive inhibitor of BCR-ABL overrides imatinib resistance. PNAS, 2005; 102: 1992-1997.
-
(2005)
PNAS
, vol.102
, pp. 1992-1997
-
-
Gumireddy, K.1
Baker, S.J.2
Cosenza, S.C.3
-
20
-
-
13844317894
-
EGFR mutation and resistance of non-small-cell lung cancer to gefitinib
-
Kobayashi S., Boggon TJ., Dayaram T. et al.: EGFR mutation and resistance of non-small-cell lung cancer to gefitinib. N Engl J Med, 2005; 352: 786-792.
-
(2005)
N Engl J Med
, vol.352
, pp. 786-792
-
-
Kobayashi, S.1
Boggon, T.J.2
Dayaram, T.3
-
21
-
-
20144386787
-
Somatic mutations of the HER2 kinase domain in lung adenocarcinomas
-
Shigematsu H., Takahashi T., Nomura M. et al.: Somatic mutations of the HER2 kinase domain in lung adenocarcinomas. Cancer Res, 2005; 65: 1642-1646.
-
(2005)
Cancer Res
, vol.65
, pp. 1642-1646
-
-
Shigematsu, H.1
Takahashi, T.2
Nomura, M.3
-
22
-
-
21244500107
-
Mutational analysis of EGFR and K-RAS genes in lung adenocarcinomas
-
Soung YH., Lee JW., Kim SY. et al.: Mutational analysis of EGFR and K-RAS genes in lung adenocarcinomas. Virchows Arch, 2005; 446: 483-488.
-
(2005)
Virchows Arch
, vol.446
, pp. 483-488
-
-
Soung, Y.H.1
Lee, J.W.2
Kim, S.Y.3
-
23
-
-
22044453790
-
Erlotinib in lung cancer - Molecular and clinical predictors of outcome
-
Tsao MS., Sakurada A., Cutz JC. et al.: Erlotinib in lung cancer - molecular and clinical predictors of outcome. N Engl J Med, 2005; 253: 133-144.
-
(2005)
N Engl J Med
, vol.253
, pp. 133-144
-
-
Tsao, M.S.1
Sakurada, A.2
Cutz, J.C.3
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