Drug resistance and hippocampal damage after delayed treatment of pilocarpine-induced epilepsy in the rat

Brain Research Bulletin

Volumn 71, Issue 1-3, 2006, Pages 127-138

  Chakir, A ^a,b   Fabene, P F ^a   Ouazzani, R ^c   Bentivoglio, M ^a  

^a UNIVERSITY OF VERONA   (Italy)

^b MOHAMMED V UNIVERSITY   (Morocco)

^c IBN SINA HOSPITAL   (Morocco)

Author keywords

Antiepileptic drugs; Astrocytes; Carbamazepine; Microglia; Parvalbumin; Seizure

Indexed keywords

ANIMALS; ANTICONVULSANTS; BRAIN DAMAGE, CHRONIC; CARBAMAZEPINE; CONVULSANTS; DISEASE MODELS, ANIMAL; DOWN-REGULATION; DRUG ADMINISTRATION SCHEDULE; DRUG RESISTANCE; EPILEPSY; EPILEPSY, TEMPORAL LOBE; GLIOSIS; HIPPOCAMPUS; MALE; NERVE DEGENERATION; NEURONS; PARVALBUMINS; PILOCARPINE; RATS; STATUS EPILEPTICUS; TIME FACTORS;

EID: 33750989919     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainresbull.2006.08.009     Document Type: Article

References (53)

1. André V., Marescaux C., Nehlig A., and Fritschy J.M. Alterations of hippocampal GAbaergic system contribute to development of spontaneous recurrent seizures in the rat lithium-pilocarpine model of temporal lobe epilepsy. Hippocampus 11 (2001) 452-468
2. Angulo M.C., Kozlov A.S., Charpak S., and Audinat E. Glutamate released from glial cells synchronizes neuronal activity in the hippocampus. J. Neurosci. 24 (2004) 6920-6927
3. Arida R.M., Scorza F.A., Peres C.A., and Cavalheiro E.A. The course of untreated seizures in the pilocarpine model of epilepsy. Epilepsy Res. 34 (1999) 99-107
4. Bouilleret V., Loup F., Kiener T., Marescaux C., and Fritschy J.M. Early loss of interneurons and delayed subunit-specific changes in GABA(A)-receptor expression in a mouse model of mesial temporal lobe epilepsy. Hippocampus 10 (2000) 305-324
5. Brandt C., Ebert U., and Loscher W. Epilepsy induced by extended amygdala-kindling in rats: lack of clear association between development of spontaneous seizures and neuronal damage. Epilepsy Res. 62 (2004) 135-156
6. Brodie M.J., and Dichter M.A. Antiepileptic drugs. N. Engl. J. Med. 334 (1996) 168-175
7. Buckmaster P.S., and Dudek F.E. Neuron loss, granule cell axon reorganization, and functional changes in the dentate gyrus of epileptic kainate-treated rats. J. Comp. Neurol. 385 (1997) 385-404
8. Capella H.M., and Lemos T. Effect on epileptogenesis of carbamazepine treatment during the silent period of the pilocarpine model of epilepsy. Epilepsia 43 Suppl. 5 (2002) 110-111
9. Celio M.R. Calbindin D-28 k and parvalbumin in the rat nervous system. Neuroscience 35 (1990) 375-475
10. Coggeshall R.E., and Lekan H.A. Methods for determining numbers of cells and synapses: a case for more uniform standards of review. J. Comp. Neurol. 364 (1996) 6-15
11. Covolan L., and Mello L.E. Temporal profile of neuronal injury following pilocarpine or kainic acid-induced status epilepticus. Epilepsy Res. 39 (2000) 133-152
12. De Simoni M.G., Perego C., Ravizza T., Moneta D., Conti M., Marchesi F., De Luigi A., Garattini S., and Vezzani A. Inflammatory cytokines and related genes are induced in the rat hippocampus by limbic status epilepticus. Eur. J. Neurosci. 12 (2000) 2623-2633
13. Devinsky O. Diagnosis and treatment of temporal lobe epilepsy. Rev. Neurol. Dis. 1 (2004) 2-9
14. Eriksson C., Winblad B., and Schultzberg M. Kainic acid induced expression of interleukin-1 receptor antagonist mRNA in the rat brain. Brain Res. Mol. Brain Res. 58 (1998) 195-208
15. Fabene P.F., Correia L., Carvalho R.A., Cavalheiro E.A., and Bentivoglio M. The spiny rat Proechimys guyannensis as model of resistance to epilepsy: chemical characterization of hippocampal cell populations and pilocarpine-induced changes. Neuroscience 104 (2001) 979-1002
16. Fabene P.F., Marzola P., Sbarbati A., and Bentivoglio M. Magnetic resonance imaging of changes elicited by status epilepticus in the rat brain: diffusion-weighted and T2-weighted images, regional blood volume maps, and direct correlation with tissue and cell damage. Neuroimage 18 (2003) 375-389
17. Freund T.F., and Buzsaki G. Interneurons of the hippocampus. Hippocampus 6 (1996) 347-470
18. Garzillo C.L., and Mello L.E. Characterization of reactive astrocytes in the chronic phase of the pilocarpine model of epilepsy. Epilepsia 43 Suppl. 5 (2002) 107-109
19. Gorter J.A., van Vliet E.A., Aronica E., and Lopes da Silva F.H. Progression of spontaneous seizures after status epilepticus is associated with mossy fibre sprouting and extensive bilateral loss of hilar parvalbumin and somatostatin-immunoreactive neurons. Eur. J. Neurosci. 13 (2001) 657-669
20. Heinemann U., Gabriel S., Jauch R., Schulze K., Kivi A., Eilers A., Kovacs R., and Lehmann T.N. Alterations of glial cell function in temporal lobe epilepsy. Epilepsia 41 Suppl. 6 (2000) S185-S189
21. Ishida A., Trescher W.H., Lange M.S., and Johnston M.V. Prolonged suppression of brain nitric oxide synthase activity by 7-nitroindazole protects against cerebral hypoxic-ischemic injury in neonatal rat. Brain Dev. 23 (2001) 349-354
22. Jones D.M., Esmaeil N., Maren S., and Macdonald R.L. Characterization of pharmacoresistance to benzodiazepines in the rat Li-pilocarpine model of status epilepticus. Epilepsy Res. 50 (2002) 301-312
23. Kwan P., and Brodie M.J. Early identification of refractory epilepsy. N. Engl. J. Med. 342 (2000) 314-319
24. Leite J.P., and Cavalheiro E.A. Effects of conventional antiepileptic drugs in a model of spontaneous recurrent seizures in rats. Epilepsy Res. 20 (1995) 93-104
25. Lemos T., and Cavalheiro E.A. Suppression of pilocarpine-induced status epilepticus and the late development of epilepsy in rats. Exp. Brain Res. 102 (1995) 423-428
26. Lemos T., and Cavalheiro E.A. Status epilepticus and the late development of spontaneous seizures in the pilocarpine model of epilepsy. Epilepsy Res. Suppl 12 (1996) 137-144
27. Loscher W. Animal models of intractable epilepsy. Prog. Neurobiol. 53 (1997) 239-258
28. Meinardi H., Scott R.A., Reis R., and Sander J.W. The treatment gap in epilepsy: the current situation and ways forward. Epilepsia 42 (2001) 136-149
29. Mello L.E., Cavalheiro E.A., Tan A.M., Kupfer W.R., Pretorius J.K., Babb T.L., and Finch D.M. Circuit mechanisms of seizures in the pilocarpine model of chronic epilepsy: cell loss and mossy fiber sprouting. Epilepsia 34 (1993) 985-995
30. Nairismagi J., Pitkanen A., Kettunen M.I., Kauppinen R.A., and Kubova H. Status epilepticus in 12-day-old rats leads to temporal lobe neurodegeneration and volume reduction: a histologic and MRI study. Epilepsia 47 (2006) 479-488
31. Preux P.M., and Druet-Cabanac M. Epidemiology and aetiology of epilepsy in sub-Saharan Africa. Lancet Neurol. 4 (2005) 21-31
32. Racine R.J. Modification of seizure activity by electrical stimulation. II. Motor seizure 1389. Electroencephalogr. Clin. Neurophysiol. 32 (1972) 281-294
33. Regesta G., and Tanganelli P. Clinical aspects and biological bases of drug-resistant epilepsies. Epilepsy Res. 34 (1999) 109-122
34. Remy S., and Beck H. Molecular and cellular mechanisms of pharmacoresistance in epilepsy. Brain 129 (2006) 18-35
35. Rizzi M., Perego C., Aliprandi M., Richichi C., Ravizza T., Colella D., Veliskova J., Moshe S.L., De Simoni M.G., and Vezzani A. Glia activation and cytokine increase in rat hippocampus by kainic acid-induced status epilepticus during postnatal development. Neurobiol. Dis. 14 (2003) 494-503
36. Robinson A.P., White T.M., and Mason D.W. Macrophage heterogeneity in the rat as delineated by two monoclonal antibodies MRC OX-41 and MRC OX-42, the latter recognizing complement receptor type 3. Immunology 57 (1986) 239-247
37. Saraceno B. The WHO World Health Report 2001 on mental health. Epidemiol. Psichiatr. Soc. 11 (2002) 83-87
38. Schmidt D., and Loscher W. Drug resistance in epilepsy: putative neurobiologic and clinical mechanisms. Epilepsia 46 (2005) 858-877
39. Scorza F.A., Arida R.M., Cysneiros R.M., Priel M.R., de Albuquerque M., and Cavalheiro E.A. The effects of alcohol intake and withdrawal on the seizures frequency and hippocampal morphology in rats with epilepsy. Neurosci. Res. 47 (2003) 323-328
40. S.D. Shorvon, The epidemiology and treatment of chronic and refractory epilepsy, Epilepsia 37 (Suppl. 2) (1996) S1-S3.
41. Sloviter R.S. Calcium-binding protein (calbindin-D28 k) and parvalbumin immunocytochemistry: localization in the rat hippocampus with specific reference to the selective vulnerability of hippocampal neurons to seizure activity. J. Comp. Neurol. 280 (1989) 183-196
42. Sloviter R.S. Permanently altered hippocampal structure, excitability, and inhibition after experimental status epilepticus in the rat: the "dormant basket cell" hypothesis and its possible relevance to temporal lobe epilepsy. Hippocampus 1 (1991) 41-66
43. Stables J.P., Bertram E., Dudek F.E., Holmes G., Mathern G., Pitkanen A., and White H.S. Therapy discovery for pharmacoresistant epilepsy and for disease-modifying therapeutics: summary of the NIH/NINDS/AES models II workshop. Epilepsia 44 (2003) 1472-1478
44. Takei Y., Takashima S., Ohyu J., Matsuura K., Katoh N., Takami T., Miyajima T., and Hoshika A. Different effects between 7-nitroindazole and L-NAME on cerebral hemodynamics and hippocampal lesions during kainic acid-induced seizures in newborn rabbits. Brain Dev. 23 (2001) 406-413
45. Tian G.F., Azmi H., Takano T., Xu Q., Peng W., Lin J., Oberheim N., Lou N., Wang X., Zielke H.R., Kang J., and Nedergaard M. An astrocytic basis of epilepsy. Nat. Med. 11 (2005) 973-981
46. Turski L., Cavalheiro E.A., Sieklucka-Dziuba M., Ikonomidou-Turski C., Czuczwar S.J., and Turski W.A. Seizures produced by pilocarpine: neuropathological sequelae and activity of glutamate decarboxylase in the rat forebrain. Brain Res. 398 (1986) 37-48
47. Turski W.A., Cavalheiro E.A., Schwarz M., Czuczwar S.J., Kleinrok Z., and Turski L. Limbic seizures produced by pilocarpine in rats: behavioural, electroencephalographic and neuropathological study. Behav. Brain Res. 9 (1983) 315-335
48. van Vliet E.A., Aronica E., Redeker S., and Gorter J.A. Expression and cellular distribution of major vault protein: a putative marker for pharmacoresistance in a rat model for temporal lobe epilepsy. Epilepsia 45 (2004) 1506-1516
49. van Vliet E.A., Redeker S., Aronica E., Edelbroek P.M., and Gorter J.A. Expression of multidrug transporters MRP1, MRP2, and BCRP shortly after status epilepticus, during the latent period, and in chronic epileptic rats. Epilepsia 46 (2005) 1569-1580
50. Vessal M., Dugani C.B., Solomon D.A., McIntyre B.W., and Ivy G.O. Might astrocytes play a role in maintaining the seizure-prone state?. Brain Res. 1044 (2005) 190-196
51. Volk H.A., and Loscher W. Multidrug resistance in epilepsy: rats with drug-resistant seizures exhibit enhanced brain expression of P-glycoprotein compared with rats with drug-responsive seizures. Brain 128 (2005) 1358-1368
52. Voutsinos-Porche B., Koning E., Kaplan H., Ferrandon A., Guenounou M., Nehlig A., and Motte J. Temporal patterns of the cerebral inflammatory response in the rat lithium-pilocarpine model of temporal lobe epilepsy. Neurobiol. Dis. 17 (2004) 385-402
53. Yabuuchi K., Minami M., Katsumata S., and Satoh M. In situ hybridization study of interleukin-1 beta mRNA induced by kainic acid in the rat brain. Brain Res. Mol. Brain Res. 20 (1993) 153-161