Placental transport of brevetoxin-3 in CD-1 mice

Toxicon

Volumn 48, Issue 8, 2006, Pages 1018-1026

  Benson, Janet M ^a   Gomez, Andrea P ^a   Statom, Gloria L ^a   Tibbetts, Brad M ^a   Fleming, Lora E ^b   Backer, Lorraine C ^c   Reich, Andrew ^d   Baden, Daniel G ^e  

^a LOVELACE RESPIRATORY RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF MIAMI   (United States)

^c NATIONAL CENTER FOR ENVIRONMENTAL HEALTH   (United States)

^d FLORIDA DEPARTMENT OF HEALTH   (United States)

^e UNIVERSITY OF NORTH CAROLINA WILMINGTON   (United States)

Author keywords

Brevetoxin 3; Intratracheal instillation; Mice; Placental transport

Indexed keywords

BREVETOXIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; GESTATIONAL AGE; MALE; MOUSE; NONHUMAN; OSMOTIC MINIPUMP; PLACENTAL TRANSFER; PREGNANCY; PRIORITY JOURNAL; RADIOACTIVITY; TISSUE DISTRIBUTION; TISSUE LEVEL;

ANIMALS; BIOLOGICAL TRANSPORT; FEMALE; FETUS; MARINE TOXINS; MATERNAL-FETAL EXCHANGE; MICE; MICE, INBRED STRAINS; OXOCINS; PLACENTA; PREGNANCY;

EID: 33750964851     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2006.08.008     Document Type: Article

References (37)

1. Abraham W.M., Bourdelais A.J., Sabater J.R., Ahmed A., Lee T.A., Serebriakov I., and Baden D.G. Airway responses to aerosolized brevetoxins in an animal model of asthma. Am. J. Respir. Crit. Care Med. 171 (2005) 26-34
2. Abraham W.M., Bourdelais A.J., Ahmed A., Serebriakov I., and Baden D.G. Effects of inhaled brevetoxins in allergic airways: toxin-allergen interactions and pharmacologic intervention. Environ. Health Perspect. 113 5 (2005) 632-637
3. Backer L.C., Fleming L.E., Rowan A., Cheng Y.S., Benson J., Pierce R.H., Zaias J., Bean J., Bossart G.D., Johnson D., Quimbo R., and Baden D.G. Recreational exposure to aerosolized brevetoxins during Florida red tide events. Harmful Algae 2 (2003) 19-28
4. Backer L.C., Kirkpatrick B., Fleming L.E., Cheng Y.S., Pierce R., Bean J.A., Clark R., Johnson D., Wanner A., Tamer R., Zhou Y., and Baden D. Occupational exposure to aerosolized brevetoxins during Florida red tide events: effects on a healthy worker population. Environ. Health Perspect. 113 5 (2005) 644-649
5. Baden D.G. Biochemistry of the brevetoxins: potent activators of voltage-sensitive sodium channels. FASEB J 3 (1989) 1807-1817
6. Baden D.G., Mende J.J., Bikhazi G., and Leung I. Bronchoconstriction caused by Florida red tide toxins. Toxicon 20 (1982) 929-932
7. Benson J.M., Tischler D.L., and Baden D.G. Uptake, tissue distribution, and excretion of brevetoxin 3 administered to rats by intratracheal instillation. J. Toxicol. Environ. Health A 56 (1999) 345-355
8. Benson J., Hahn F., March T., McDonald J., Sopori M., Seagrave J., Gomez A., Bourdelais A., Naar J., Zaias J., Bossart G., and Baden D. Inhalation toxicity of brevetoxin 3 in rats exposed for 5 days. J. Toxicol. Environ. Health A 67 18 (2004) 1443-1456
9. Benson J.M., Hahn F.F., March T.H., McDonald J.D., Gomez A.P., Sopori M.L., Bourdelais A.J., Naar J., Zaias J., Bossart G.D., and Baden D.G. Inhalation toxicity of brevetoxin 3 in rats exposed for twenty-two days. Environ. Health Perspect. 113 (2005) 626-631
10. Cattet M., and Geraci J.R. Distribution and elimination of ingested brevetoxin (PbTx3) in rats. Toxicon 31 (1993) 1483-1486
11. Cheng Y.S., Zhou Y., Irvin C.M., Pierce R.H., Naar J., Backer L.C., Fleming L.E., Kirkpatrick B., and Baden D.G. Characterization of marine aerosol for assessment of human exposure to brevetoxins. Environ. Health Perspect. 113 (2005) 638-643
12. Fleming L.E., Backer L.C., and Baden D.G. Overview of aerosolized Florida red tide toxins: exposures and effects. Environ Health Perspect. 113 5 (2005) 618-620
13. Fleming L.E., Kirkpatrick B., Backer L.C., Bean J.A., Wanner A., Dalpra D., Tamer R., Zaias J., Cheng Y.S., Pierce R., Naar J., Abraham W., Clark R., Zhou Y., Henry M.S., Johnson D., Van de Bogart G., Bossart G.D., Harrington M., and Baden D.G. Initial evaluation of the effects of aerosolized Florida red tide toxins (brevetoxins) in persons with asthma. Environ. Health Perspect. 113 5 (2005) 650-657
14. Guvenius D.M., Aronsson A., Ekman-Ordeberg G., Bergman A., and Noren K. Human prenatal and postnatal exposure to polybrominated diphenyl ethers, polychlorinated biphenyls, polychlorobiphenylols, and pentachlorophenol. Environ. Health Perspect. 11 (2003) 1235-1241
15. Kimm-Brinson K.L., and Ramsdell J.S. The red tide toxin, brevetoxin, induces embryo toxicity and developmental abnormalities. Environ. Health Perspect. 109 (2001) 377-381
16. Kirkpatrick B., Fleming L.E., Backer L.C., Bean J.A., Tamer R., Kirkpatrick G., Kane T., Wanner A., Dalpra D., Reich A., and Baden D.G. Environmental exposures to Florida red tides: effects on emergency room respiratory diagnoses admissions. Harmful Algae 5 (2006) 526-533
17. Leazer T.M., and Klaassen C.D. The presence of xenobiotic transporters in rat placenta. Drug Metab. Dispos. 31 2 (2003) 153-167
18. Mazdai A., Dodder N.G., Abernathy M.P., Hites R.A., and Bigsby R.M. Polybrominated diphenyl ethers in maternal and fetal blood samples. Environ. Health Perspect. 111 (2003) 1249-1252
19. Meerts I.A., Assink Y., Cenijin P.H., Van Den Berg J.H., Weijers B.M., Bergman A., Koeman J.H., and Brouwer A. Placental transfer of a hydroxylated polychlorinated biphenyl and effects on fetal and maternal thyroid hormone homeostasis in the rat. Toxicol. Sci. 68 (2002) 361-371
20. Moon R.T., and Morrill J.B. The effects of Gymnodinium breve lysate on the larval development of the sea urchin Lytechinus variegates. J. Environ. Sci. Health A 11 10,11 (1976) 673-683
21. Naar J., Bourdelais A., Tomas C., Kubanek J., Whitney P.L., Flewelling L., Steidinger K., Lancaster J., and Baden D.G. A competitive ELISA to detect brevetoxins from Karenia brevis (formerly Gymnodinium breve) in seawater, shellfish, and mammalian body fluid. Environ. Health Perspect. 110 (2002) 179-185
22. National Research Council. Guide for the Care and Use of Laboratory Animals (1996), National Academies Press, Washington, DC
23. Needleman J.L. Behavioral toxicology. Environ. Health Perspect. 103 (1995) 77-79
24. Perera F.P., Jedrychowski W., Rauh V., and Whyatt R.M. Molecular epidemiologic research on the effects of environmental pollutants on the fetus. Environ. Health Perspect. 107 Suppl. 3 (1999) 451-460
25. Poli M.A., Mende T.J., and Baden D.G. Brevetoxins, unique activators of voltage-sensitive sodium channels, bind to specific sites in rat brain synaptosomes. Mol. Pharmacol. 30 2 (1986) 129-135
26. Poli M.A., Templeton C.B., Thompson W.L., and Hewetson J.F. Distribution and elimination of brevetoxin-3 in rats. Toxicon 28 (1990) 903-910
27. Poli, M.A., Templeton, C.B., Pace, J.G., Hines, H.B., 1990b. Detection, metabolism, and pathophysiology of brevetoxins. In: Hall, S., Strichartz, G. (Eds.), Marine Toxins Origin, Structure and Molecular Pharmacology. American Chemical Society, ACS Symposium Series, vol. 418, Washington, DC, pp. 176-191.
28. Poli M.A., Musser S.M., Dickey R.W., Eilers P.P., and Hall S. Neurotoxic shellfish poisoning and brevetoxin metabolites: a case study from Florida. Toxicon 38 (2000) 981-993
29. Riley C.M., Holt S.A., Holt J., Burskey E.J., and Arnold C.R. Mortality of larval red drum (Sciaenops ocellatus) associated with a Ptychodiscus brevis red tide. Contrib. Mar. Sci. 31 (1989) 137-146
30. Rodier P.M. Developing brain as a target of toxicity. Environ. Health Perspect. 103 (1995) 63-66
31. Roman B.L., Timms B.G., Prins G.S., and Peterson R.E. In utero and lactational exposure of the male rat to 2,3,7,8-tetrachlorodibenzo-p-dixoin impairs prostate development. 2. Effects on growth and cytodifferentiation. Toxicol. Appl. Pharmacol. 150 (1998) 254-270
32. Sayer A., Hu Q., Bourdelais A.J., Baden D.G., and Gibson J.E. The effect of brevenal on brevetoxin-induced DNA damage in human lymphocytes. Arch. Toxicol. 79 (2005) 683-688 Epub 2005 Jun 29
33. Sinjari T., and Darnerud P.O. Hydroxylated polychlorinated biphenyls: placental transfer and effects on thyroxine in the foetal mouse. Xenobiotica 28 (1998) 21-30
34. Tibbetts B.M., Baden D.G., and Benson J.M. Uptake, tissue distribution, and excretion of brevetoxin-3 administered to mice by intratracheal instillation. J. Toxicol. Environ. Health. Part A 69 (2006) 1325-1335
35. Unadkat J.D., Dahlin A., and Vijay S. Placental drug transporters. Curr. Drug Metab. 5 (2004) 125-131
36. Wang W., Hua Y., Wang G., and Cole R.B. Characterization of rat liver microsomal and hepatocytal metabolites of brevetoxins by liquid chromatography-electrospray tandem mass spectrometry. Anal. Bioanal. Chem. 383 (2005) 67-75
37. You G. The role of organic ion transporters in drug disposition: an update. Curr. Drug Metab. 5 1 (2004) 55-62