Brain processing of hemorphin-7 peptides in various subcellular fractions from rats

Peptides

Volumn 27, Issue 12, 2006, Pages 3331-3340

  Murillo, Laurence ^a   Piot, Jean Marie ^a   Coitoux, Corinne ^b   Fruitier Arnaudin, Ingrid ^a  

^a Laboratoire de Biotechnologies et de Chimie Biorganique (LBCB)   (France)

^b Institut Universitaire de Technologie   (France)

Author keywords

ACE; Brain aminopeptidase; Brain subcellular fractions; Hemorphins; Mass spectrometry; Peptide catabolism

Indexed keywords

CAPTOPRIL; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; LEUCYLVALYLVALYLTYROSYLPROLYLTRYPTOPHYLTHREONYLGLUTAMINYLARGINYL PHENYLALANINE; MEMBRANE ENZYME; NEUROPEPTIDE; TYROSYLPROLYLTRYPTOPHYLTHREONYLGLUTAMINYLARGINYLPHENYLALANINE; UNCLASSIFIED DRUG; VALYLVALYLTYROSYLPROLYLTRYPTOPHYLTHREONYLGLUTAMINYLARGINYLPHENYLALANINE;

AMINO TERMINAL SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN HOMOGENATE; BRAIN TISSUE; CARBOXY TERMINAL SEQUENCE; CELL FRACTIONATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ELECTROSPRAY MASS SPECTROMETRY; ENZYME ACTIVITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; MICROSOME; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN ISOLATION; PROTEIN PROCESSING; PROTEIN STABILITY; RAT;

ANIMALS; BRAIN; HEMOGLOBINS; MALE; PEPTIDE FRAGMENTS; RATS; RATS, WISTAR; SUBCELLULAR FRACTIONS;

EID: 33750955974     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2006.09.014     Document Type: Article

References (36)

1. Albiston A.L., McDowall S.G., Matsacos D., Sim P., Clune E., Mustafa T., et al. Evidence that the angiotensin IV (AT(4)) receptor is the enzyme insulin-regulated aminopeptidase. J Biol Chem 276 (2001) 48623-48626
2. Cesarone C.F., Bolognesi C., and Santi L. Improved microfluorometric DNA determination in biological material using 33258 Hoechst. Anal Biochem 100 (1979) 188-197
3. Costerousse O., Allegrini J., Lopez M., and Alhenc-Gelas F. Angiotensin I-converting enzyme in human circulating mononuclear cells: genetic polymorphism of expression in T-lymphocytes. Biochem J 290 Pt 1 (1993) 33-40
4. Dagouassat N., Garreau I., Sannier F., Zhao Q., and Piot J.M. Generation of VV-hemorphin-7 from globin by peritoneal macrophages. FEBS Lett 382 (1996) 37-42
5. Duethman D., Dewan N., and Conlon J.M. Isolation of the opioid peptide Leu-Val-Val-hemorphin-7 from bronchoalveolar lavage fluid of a patient with non-small cell lung cancer. Peptides 21 (2000) 137-142
6. Erdos E.G., and Yang H.Y. An enzyme in microsomal fraction of kidney that inactivates bradykinin. Life Sci 6 (1967) 569-574
7. Fruitier-Arnaudin I., Cohen M., Coitoux C., and Piot J.M. In vitro metabolism of LVV-Hemorphin-7 by renal cytosol and purified prolyl endopeptidase. Peptides 24 (2003) 1201-1206
8. Fruitier I., Garreau I., Lacroix A., Cupo A., and Piot J.M. Proteolytic degradation of hemoglobin by endogenous lysosomal proteases gives rise to bioactive peptides: hemorphins. FEBS Lett 447 (1999) 81-86
9. Glamsta E.L., Marklund A., Hellman U., Wernstedt C., Terenius L., and Nyberg F. Isolation and characterization of a hemoglobin-derived opioid peptide from the human pituitary gland. Regul Pept 34 (1991) 169-179
10. Glamsta E.L., Meyerson B., Silberring J., Terenius L., and Nyberg F. Isolation of a hemoglobin-derived opioid peptide from cerebrospinal fluid of patients with cerebrovascular bleedings. Biochem Biophys Res Commun 184 (1992) 1060-1066
11. Glamsta E.L., Morkrid L., Lantz I., and Nyberg F. Concomitant increase in blood plasma levels of immunoreactive hemorphin-7 and beta-endorphin following long distance running. Regul Pept 49 (1993) 9-18
12. Gray E.G., and Whittaker V.P. The isolation of nerve endings from brain: an electron-microscopic study of cell fragments derived by homogenization and centrifugation. J Anat 96 (1962) 79-88
13. Henry R.J., Chiamori N., Golub O.J., and Berkman S. Revised spectrophotometric methods for the determination of glutamic-oxalacetic transaminase, glutamic-pyruvic transaminase, and lactic acid dehydrogenase. Am J Clin Pathol 34 (1960) 381-398
14. Karelin A.A., Philippova M.M., and Ivanov V.T. Proteolytic degradation of hemoglobin in erythrocytes leads to biologically active peptides. Peptides 16 (1995) 693-697
15. Karelin A.A., Philippova M.M., Karelina E.V., and Ivanov V.T. Isolation of endogenous hemorphin-related hemoglobin fragments from bovine brain. Biochem Biophys Res Commun 202 (1994) 410-415
16. Krueger B.K., Forn J., and Greengard P. Depolarization-induced phosphorylation of specific proteins, mediated by calcium ion influx, in rat brain synaptosomes. J Biol Chem 252 (1977) 2764-2773
17. Labarca C., and Paigen K. A simple, rapid, and sensitive DNA assay procedure. Anal Biochem 102 (1980) 344-352
18. Liebmann C., Schrader U., and Brantl V. Opioid receptor affinities of the blood-derived tetrapeptides hemorphin and cytochrophin. Eur J Pharmacol 166 (1989) 523-526
19. Lowry O.H., Rosebrough N.J., Farr A.L., and Randall R.J. Protein measurement with the Folin phenol reagent. J Biol Chem 193 (1951) 265-275
20. Makinen K.K., Sewon L., and Makinen P. Analysis in gingival crevicular fluid of two oligopeptides derived from human hemoglobin beta-chain. J Periodontal Res 31 (1996) 43-46
21. Moeller I., Chai S.Y., Smith I., Lew R., and Mendelsohn F.A. Haemorphin peptides may be endogenous ligands for brain angiotensin AT4 receptors. Clin Exp Pharmacol Physiol Suppl 25 (1998) S68-S71
22. Moeller I., Lew R.A., Mendelsohn F.A., Smith A.I., Brennan M.E., Tetaz T.J., et al. The globin fragment LVV-hemorphin-7 is an endogenous ligand for the AT4 receptor in the brain. J Neurochem 68 (1997) 2530-2537
23. Nydahl K.S., Pierson J., Nyberg F., Caprioli R.M., and Andren P.E. In vivo processing of LVV-hemorphin-7 in rat brain and blood utilizing microdialysis combined with electrospray mass spectrometry. Rapid Commun Mass Spectrom 17 (2003) 838-844
24. Oyama R., Yamamoto H., and Titani K. Glutamine synthetase, hemoglobin alpha-chain, and macrophage migration inhibitory factor binding to amyloid beta-protein: their identification in rat brain by a novel affinity chromatography and in Alzheimer's disease brain by immunoprecipitation. Biochim Biophys Acta 1479 (2000) 91-102
25. Piot J.M., Zhao Q., Guillochon D., Ricart G., and Thomas D. Isolation and characterization of two opioid peptides from a bovine hemoglobin peptic hydrolysate. Biochem Biophys Res Commun 189 (1992) 101-110
26. Poljak A., McLean C.A., Sachdev P., Brodaty H., and Smythe G.A. Quantification of hemorphins in Alzheimer's disease brains. J Neurosci Res 75 (2004) 704-714
27. Skold K., Svensson M., Kaplan A., Bjorkesten L., Astrom J., and Andren P.E. A neuroproteomic approach to targeting neuropeptides in the brain. Proteomics 2 (2002) 447-454
28. Slemmon J.R., Hughes C.M., Campbell G.A., and Flood D.G. Increased levels of hemoglobin-derived and other peptides in Alzheimer's disease cerebellum. J Neurosci 14 (1994) 2225-2235
29. Slemmon J.R., Wengenack T.M., and Flood D.G. Profiling of endogenous peptides as a tool for studying development and neurological disease. Biopolymers 43 (1997) 157-170
30. Tomboly C., Peter A., and Toth G. In vitro quantitative study of the degradation of endomorphins. Peptides 23 (2002) 1573-1580
31. Trounce I.A., Kim Y.L., Jun A.S., and Wallace D.C. Assessment of mitochondrial oxidative phosphorylation in patient muscle biopsies, lymphoblasts, and transmitochondrial cell lines. Methods Enzymol 264 (1996) 484-509
32. Vermilion J.L., and Coon M.J. Highly purified detergent-solubilized NADPH-cytochrome P-450 reductase from phenobarbital-induced rat liver microsomes. Biochem Biophys Res Commun 60 (1974) 1315-1322
33. Wu C.W., Liao P.C., Yu L., Wang S.T., Chen S.T., Wu C.M., et al. Hemoglobin promotes Abeta oligomer formation and localizes in neurons and amyloid deposits. Neurobiol Dis 17 (2004) 367-377
34. Zadina J.E., Kastin A.J., Ge L.J., and Brantl V. Hemorphins, cytochrophins, and human beta-casomorphins bind to antiopiate (TYR-MIF-1) as well as opiate binding sites in rat brain. Life Sci 47 (1990) PL25-PL30
35. Zhao Q., Sannier F., Garreau I., Guillochon D., and Piot J.M. Inhibition and inhibition kinetics of angiotensin converting enzyme activity by hemorphins, isolated from a peptic bovine hemoglobin hydrolysate. Biochem Biophys Res Commun 204 (1994) 216-223
36. Zhao Q., Sannier F., and Piot J.M. Kinetics of appearance of four hemorphins from bovine hemoglobin peptic hydrolysates by HPLC coupled with photodiode array detection. Biochim Biophys Acta 1295 (1996) 73-80