Proteolytic degradation of hemoglobin by endogenous lysosomal proteases gives rise to bioactive peptides: Hemorphins

FEBS Letters

Volumn 447, Issue 1, 1999, Pages 81-86

  Fruitier, Ingrid ^a   Garreau, Isabelle ^a   Lacroix, André ^b   Cupo, Anny ^c   Piot, Jean Marie ^a  

^a Pole Sci Technol Univ R   (France)

^b CENTRE D ETUDES BIOLOGIQUES DE CHIZÉ   (France)

^c INSTITUT DE PHARMACOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

Hemoglobin; Hemorphin; HPLC; Lysosome; Proteolysis; Radioimmunoassay

Indexed keywords

HEMOGLOBIN; HEMORPHIN; HEMORPHIN 7; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; LIVER; LYSOSOME; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; RADIOIMMUNOASSAY; RAT;

ANIMALS; ENDOPEPTIDASES; HEMOGLOBINS; LIVER; LYSOSOMES; MACROPHAGES; MALE; OPIOID PEPTIDES; PEPTIDE FRAGMENTS; RATS; RATS, WISTAR; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 0032974250     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(99)00271-9     Document Type: Article

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