Active CMOS array sensor for time-resolved fluorescence detection

IEEE Journal of Solid-State Circuits

Volumn 41, Issue 11, 2006, Pages 2521-2530

  Patounakis, George ^a,b   Shepard, Kenneth L ^a,b   Levicky, Rastislav ^b  

^a IEEE   (United States)

^b Columbia University ^*  (United States)

Author keywords

Biochips; Biosensor; CMOS imager; Fluorescence spectroscopy; Microarray

Indexed keywords

BIOCHIPS; CMOS IMAGERS; FLUORESCENCE SPECTROSCOPY; MICROARRAYS;

ASSAYS; BIOMEDICAL ENGINEERING; BIOSENSORS; DIAGNOSIS; FLUORESCENCE; SPECTROSCOPIC ANALYSIS;

CMOS INTEGRATED CIRCUITS;

EID: 33750811882     PISSN: 00189200     EISSN: None     Source Type: Journal    
DOI: 10.1109/JSSC.2006.883316     Document Type: Conference Paper

References (21)

1. K. U. Mir and E. M. Southern, "Sequence variation in genes and genomic data: Methods for large-scale analysis," Annu. Rev. Genom. Human Genetics, vol. 1, pp. 329-360, Sep. 2000.
2. M. F. Templin, D. Stoll, M. Schrenk, P. C. Traub, C. F. Vohringer, and T. O. Joos, "Protein microarray technology," Trends Biotechnol., vol. 20, pp. 160-166, Apr. 2002.
3. M. Schena, R. A. Heller, T. P. Theriault, K. Konrad, E. Lachenmeier, and R. W. Davis, "Microarrays: Biotechnology's discovery platform for functional genomics," Trends Biotechnol., vol. 16, pp. 301-306, Jul. 1998.
4. J. G. Hacia and F. S. Collins, "Mutational analysis using oligonu-cleotide microarrays," J. Medical Genet., pp. 730-736, Oct. 1999.
5. X. Michalet, F. F. Pinaud, L. A. Bentolila, J. M. Tsay, S. Doose, J. J. Li, G. Sundaresan, A. M. Wu, S. S. Gambhir, and S. Weiss, "Quantum dots for live cells, in vivo imaging, and diagnostics," Science, vol. 307, pp. 538-544, Jan. 2005.
6. S. L. McIntosh, B. K. Nunnally, A. R. Nesbit, T. G. Deligeorgiev, N. I. Gadjev, and L. B. McGown, "Fluorescence lifetime for on-the-fly multiplex detection of DNA restriction fragments in capillary electrophoresis," Anal. Chem., vol. 72, no. 21, pp. 5444-5449, Nov. 2000.
7. P. I. H. Bastiaens and A. Squire, "Fluorescence lifetime imaging microscopy: Spatial resolution of biochemical processes in the cell," Trends Cell Biology, vol. 9, pp. 48-52, Feb. 1999.
8. R. A. Cardullo, S. Agrawal, C. Flores, P. C. Zamecnik, and D. E. Wolf, "Detection of nucleic acid hybridization by nonradiative fluorescence resonance energy transfer," Proc. Nat. Acad. Sci., vol. 85, pp. 8790-8794, Dec. 1988.
9. D. V. O'Connor and D. Phillips, Time-Correlated Single Photon Counting. New York: Academic, 1984.
10. G. Patounakis, K. L. Shepard, and R. Levicky, "Active CMOS biochip for time-resolved fluorescence detection," in Proc. Symp. VLSI Circuits, Jun. 2005, pp. 68-71.
11. R. A. Yotter and D. M. Wilson, "A review of photodetectors for sensing light-emitting reporters in biological systems," IEEE Sensors J., vol. 3, no. 3, pp. 288-303, Jun. 2003.
12. -6 lux bioluminescence detection system-on-chip, " in Proc. IEEE Int. Solid-State Circuits Conf., Feb. 2004, pp. 222-223.
13. S. J. Daubert, D. Vallancourt, and Y. P. Tsividis, "Current copier cells," Electron. Lett., vol. 24, pp. 1560-1562, Oct. 1988.
14. S. J. Daubert and D. Vallancourt, "A transistor-only current-mode SA modulator," IEEE J. Solid-State Circuits, vol. 27, no. 5, pp. 821-830, May 1992.
15. B. Razavi, Design of Analog CMOS Integrated Circuits. New York: McGraw-Hill, 2001.
16. D. Hyun and G. Fischer, "Limit cycles and pattern noise in single-stage single-bit delta-sigma modulators," IEEE Trans. Circuits Syst. I, Fundam. Theory Appl., vol. 49, no. 5, pp. 646-656, May 2002.
17. H. Tian, B. Fowler, and A. El Gamal, "Analysis of temporal noise in CMOS photodiode active pixel sensor," IEEE J. Solid-State Circuits, vol. 36, no. 1, pp. 92-101, Jan. 2001.
18. T. M. Niebauer, R. Schilling, K. Danzmann, A. Rudiger, and W. Winkler, "Nonstationary shot noise and its effect on the sensitivity of interferometers," Phys. Rev. A, vol. 43, pp. 5022-5029, May 1991.
19. B. E. A. Saleh and M. C. Teich, Fundamentals of Photonics. New York: Wiley, 1991.
20. J. R. Lakowicz, Principles of Fluorescence Spectroscopy. Boston, MA: Kluwer/Plenum, 1999.
21. J. Nearing, "Mathematical tools for physics," 2003 [Online]. Available: http://www.physics.miami.edu/nearing/mathmethods