Protease-triggered photosensitizing beacon based on singlet oxygen quenching and activation

Journal of the American Chemical Society

Volumn 126, Issue 37, 2004, Pages 11450-11451

  Chen, Juan ^a   Stefflova, Klara ^a   Niedre, Mark J ^a   Wilson, Brian C ^a   Chance, Britton ^b   Glickson, Jerry D ^a   Zheng, Gang ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b PRINCESS MARGARET HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CHLOROPHYLL; PEPTIDE; PROTEINASE; PYROPEPTIDE CAR; SCAVENGER; SINGLET OXYGEN; UNCLASSIFIED DRUG;

ABSORPTION; ARTICLE; CHEMICAL STRUCTURE; ENERGY TRANSFER; ENZYMATIC ASSAY; ENZYME DEGRADATION; ENZYME SPECIFICITY; ENZYME SUBSTRATE; ENZYME SUBSTRATE COMPLEX; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; PEPTIDE SYNTHESIS; PHOTOCHEMICAL QUENCHING; PHOTOSENSITIZATION; STRUCTURE ANALYSIS;

CAROTENOIDS; CASPASE 3; CASPASES; CHLOROPHYLL; LUMINESCENT MEASUREMENTS; OLIGOPEPTIDES; PHOTOSENSITIZING AGENTS; SINGLET OXYGEN;

EID: 4544302287     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja047392k     Document Type: Article

References (12)

1. Dougherty, T. J.; Corner, C. J.; Henderson, B. W.; Jori, G.; Kessel, D.; Korbelik, M.; Moan, J.; Peng, Q. J. Natl. Cancer Inst. 1998, 90, 889-905.
2. Matayoshi, E. D.; Wang, G. T.; Krafft, G. A.; Erickson, J. Science 1990, 247, 954-958.
3. Zhang, J.; Campbell, R. E.; Ting, A. Y.; Tsien, R. Y. Nat. Rev. Mol. Cell Biol. 2002, 3, 906-918.
4. Tyagi, S.; Kramer, F. R. Nat. Biotech. 1996, 14, 303-308.
5. Weissleder, R.; Tung, C. H.; Mahmood, U.; Bogdanov, A. Nat. Biotech. 1999, 17, 375-378.
6. Nicholson, D. W.; Ali, A.; Thornberry, N. A.; Vaillancourt, J. P.; Ding, C. K.; Gallant, M.; Gareau, Y.; Griffin, P. R.; Labelle, M.; Lazebnik, Y. A.; Munday, N. A.; Raju, S. M.; Smulson, M. E.; Yamin, T.; Yu, V. L.; Miller, D. K. Nature 1998, 17, 1295-1304.
7. Zhang, M.; Zhang, Z. H.; Blessington, D.; Li, H.; Busch, T. M.; Madrak, V.; Miles, J.; Chance, B.; Glickson, J. D.; Zheng, G. Bioconjugate Chem. 2003, 14, 709-714.
8. Gust, D.; Moore, T. A.; Moore, A. L.; Jori, G.; Reddi, E. Ann. N.Y. Acad. Sci. 1993, 691, 32-47.
9. 3CN, C = MeOH; gradient, 60% A and 40% B to 10% A and 90% B in the first 20 min, then to 90% B and 10% C for another 10 min, finally to 80% B and 20% C for 10 min.
10. Niedre, M.; Secord, A. J.; Patterson, M. S.; Wilson, B. C. Cancer Res. 2003, 63, 7986-7994.
11. Foote, C. S.; Chang, Y. C.; Denny, R. W. J. Am. Chem. Soc. 1970, 92, 5216-5218.
12. Sokol, D. L.; Zhang, X.; Lu, P.; Gewirtz, A. M. Proc. Natl. Acad. Sci. U.S.A. 1998, 95, 11538-11543.