Role of integrin cross-regulation in parvovirus B19 targeting

Human Gene Therapy

Volumn 17, Issue 9, 2006, Pages 909-920

  Weigel Kelley, Kirsten A ^a   Yoder, Mervin C ^b   Chen, Linyuan ^a   Srivastava, Arun ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA1 INTEGRIN; BETA2 INTEGRIN; BETA3 INTEGRIN; CD47 ANTIGEN; INTEGRIN RECEPTOR; PARVOVIRUS VECTOR; VERY LATE ACTIVATION ANTIGEN 5; VIRUS ANTIBODY;

ARTICLE; CELL SPECIFICITY; CELL TYPE; CONTROLLED STUDY; CROSS LINKING; ERYTHROID PRECURSOR CELL; GENE SILENCING; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; INTERNALIZATION; PARVOVIRUS; PROTEIN CONFORMATION; PROTEIN EXPRESSION; REGULATORY MECHANISM; VIRAL GENE DELIVERY SYSTEM; CELL DIFFERENTIATION; CELL STRAIN K 562; IMMUNOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION;

PARVOVIRUS;

ANTIBODIES, VIRAL; CELL DIFFERENTIATION; HUMANS; INTEGRIN ALPHA5BETA1; K562 CELLS; PARVOVIRUS B19, HUMAN; SIGNAL TRANSDUCTION; TRANSDUCTION, GENETIC;

EID: 33750607604     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/hum.2006.17.909     Document Type: Article

References (69)

1. BERNARDINI, G., KIM, J.Y., GISMONDI, A., BUTCHER, E.G., and SANTONI, A. (2005). Chemoattractant induces LFA-1 associated PI 3K activity and cell migration that are dependent on Fyn signaling. FASEB J. 19, 1305-1307.
2. 1 integrin function in chronic myelogenous leukemia hematopoietic progenitors. Exp. Hematol. 27, 1384-1396.
3. BHATTACHARYYA, J., KUMAR, R., TYAGI, S., KISHORE, J., MAHAPATRA, M., and CHOUDHRY, V.P. (2005). Human parvovirus B19-induced acquired pure amegakaryocytic thrombocytopenia. Br. J. Haematol. 128, 128-129.
4. 3 and integrin-associated protein. J. Cell Biol. 130, 745-754.
5. 1 function. J. Cell Biol. 145, 889-897.
6. BOWLES, D.E., RABINOWITZ, J.E., and SAMULSKI, R.J. (2003). Marker rescue of adeno-associated virus (AAV) capsid mutants: A novel approach for chimeric AAV production. J. Virol. 77, 423-432.
7. BRAKEBUSCH, C., and FASSLER, R. (2003). The integrin-actin connection, an eternal love affair. EMBO J. 22, 2324-2333.
8. BROWN, K.E., ANDERSON, S.M., and YOUNG, N.S. (1993). Erythrocyte P antigen: Cellular receptor for B19 parvovirus. Science 262, 114-117.
9. BULTMANN, B.D., KLINGEL, K., SOTLAR, K., BOCK, C.T., BABA, H.A., SAUTER, M., and KANDOLF, R. (2003). Fatal parvovirus B19-associated myocarditis clinically mimicking ischemic heart disease: An endothelial cell-mediated disease. Hum. Pathol. 34, 92-95.
10. 3 integrin provides a binding site for Pyk2. J. Biol. Chem. 280, 14556-14562.
11. CALDERWOOD, D.A., TAI, V., DI PAOLO, G., DE CAMILLI, P., and GINSBERG, M.H. (2004). Competition for talin results in transdominant inhibition of integrin activation. J. Biol. Chem. 279, 28889-28895.
12. CARTER, P.J., and SAMULSKI, R.J. (2000). Adeno-associated viral vectors as gene delivery vehicles. Int. J. Mol. Med. 6, 17-27.
13. 2 integrin-mediated adhesion to ICAM-1 in human T cells. J. Immunol. 164, 746-753.
14. CLARK, E.A., and BRUGGE, J.S. (1995). Integrins and signal transduction pathways: The road taken. Science 268, 233-239.
15. CONLON, T.J., and FLOTTE, T.R. (2004). Recombinant adeno-associated virus vectors for gene therapy. Expert Opin. Biol. Ther. 4, 1093-1101.
16. CRYSTAL, R.G., SONDHI, D., HACKETT, N.R., KAMINSKY, S.M., WORGALL, S., STIEG, P., SOUWEIDANE, M., HOSAIN, S., HEIER, L., BALLON, D., DINNER, M., WISNIEWSKI, K., KAPLITT, M., GREENWALD, B.M., HOWELL, J.D., STRYBING, K., DYKE, J., and VOSS, H. (2004). Administration of a replication-deficient adeno-associated virus gene transfer vector expressing the human CLN2 cDNA to the brain of children with late infantile neuronal ceroid lipofuscinosis [clinical protocol]. Hum. Gene Ther. 15, 1131-1154.
17. DUBAND, J.L., NUCKOLLS, G.H., ISHIHARA, A., HASEGAWA, T., YAMADA, K.M., THIERY, J.P., and JACOBSON, K. (1988). Fibronectin receptor exhibits high lateral mobility in embryonic locomoting cells but is immobile in focal contacts and fibrillar streaks in stationary cells. J. Cell Biol. 107, 1385-1396.
18. 2-integrin ligation. Cell. Motil. Cytoskeleton 47, 174-188.
19. 1: Regulation of the functional response by soluble fibronectin. J. Cell Biol. 121, 155-162.
20. FERKOWICZ, M.J., STARR, M., XIE, X., LI, W., JOHNSON, S.A., SHELLEY, W.C., MORRISON, P.R., and YODER, M.C. (2003). CD41 expression defines the onset of primitive and definitive hematopoiesis in the murine embryo. Development 130, 4393-4403.
21. 1-antitrypsin (rAAV2-CB-hAAT) gene vector to AAT-deficient adults. Hum. Gene Ther. 15, 93-128.
22. 3 by its extracellular domain. J. Biol. Chem. 278, 26655-26665.
23. HACEIN-BEY-ABINA, S., VON KALLE, C., SCHMIDT, M., LE DEIST, F., WULFFRAAT, N., McINTYRE, E., RADFORD, L., VILLEVAL, J.L., FRASER, C.C., CAVAZZANA-CALVO, M., and FISCHER, A. (2003). A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency. N. Engl. J. Med. 348, 255-256.
24. 1-integrin- linked protein kinase. Nature 379, 91-96.
25. HIGH, K.A. (2004). Clinical gene transfer studies for hemophilia B. Semin. Thromb. Hemost. 30, 257-267.
26. 1-mediated signaling pathways by fibronectin's bin cell adhesion and matrix assembly domains. J. Cell Biol. 141, 241-253.
27. HYNES, R.O. (2002). Integrins: Bidirectional, allosteric signaling machines. Cell 110, 673-687.
28. JALALI, S., DEL POZO, M.A., CHEN, K., MIAO, H., LI, Y., SCHWARTZ, M.A., SHYY, J.Y., and CHIEN, S. (2001). Integrin-mediated mechanotransduction requires its dynamic interaction with specific extracellular matrix (ECM) ligands. Proc. Natl. Acad. Sci. U.S.A. 98, 1042-1046.
29. JIANG, Y., PROSPER, F., and VERFAILLIE, C.M. (2000). Opposing effects of engagement of integrins and stimulation of cytokine receptors on cell cycle progression of normal human hematopoietic progenitors. Blood 95, 846-854.
30. 1 and c-Kit results in opposing effect on growth and survival of hematopoietic cells via the activation of focal adhesion kinase, mitogen-activated protein kinase, and Akt signaling pathways. Blood 97, 1975-1981.
31. KASHIWAKURA, Y., TAMAYOSE, K., IWABUCHI, K., HIRAI, Y., SHIMADA, T., MATSUMOTO, K., NAKAMURA, T., WATANABE, M., OSHIMI, K., and DAIDA, H. (2005). Hepatocyte growth factor receptor is a coreceptor for adeno-associated virus type 2 infection. J. Virol. 79, 609-614.
32. 2. J. Cell Biol. 167, 1241-1253.
33. KUCIK, D.F., DUSTIN, M.L., MILLER, J.M., and BROWN, E.J. (1996). Adhesion-activating phorbol ester increases the mobility of leukocyte integrin LFA-1 in cultured lymphocytes. J. Clin. Invest. 97, 2139-2144.
34. LEITINGER, B., and HOGG, N. (2002). The involvement of lipid rafts in the regulation of integrin function. J. Cell Sci. 115, 963-972.
35. LUB, M., VAN KOOYK, Y., VAN VLIET, S.J., and FIGDOR, G.G. (1997). Dual role of the actin cytoskeleton in regulating cell adhesion mediated by the integrin lymphocyte function-associated molecule-1. Mol. Biol. Cell 8, 341-351.
36. 1 integrin antibodies that stabilize the low affinity state by preventing the swing-out of the hybrid domain. J. Biol. Chem. 279, 27466-27471.
37. MANDEL, R.J., and BURGER, C. (2004). Clinical trials in neurological disorders using AAV vectors: Promises and challenges. Curr. Opin. Mol. Ther. 6, 482-490.
38. 2 integrin-dependent leukocyte adhesion involving the urokinase receptor. Blood 96, 506-513.
39. MAZEROLLES, F., BARBAT, C., TRUCY, M., KOLANUS, W., and FISCHER, A. (2002). Molecular events associated with CD4-mediated down-regulation of LFA-1-dependent adhesion. J. Biol. Chem. 277, 1276-1283.
40. McGILVRAY, I.D., LU, Z., BITAR, R., DACKIW, A.P., DAVREUX, C.J., and ROTSTEIN, O.D. (1997). VLA-4 integrin cross-linking on human monocytic THP-1 cells induces tissue factor expression by a mechanism involving mitogen-activated protein kinase. J. Biol. Chem. 272, 10287-10294.
41. + cells. Exp. Hematol. 32, 1051-1056.
42. MIYAMOTO, S., TERAMOTO, H., COSO, O.A., GUTKIND, J.S., BURBELO, P.D., AKIYAMA, S.K., and YAMADA, K.M. (1995). Integrin function: Molecular hierarchies of cytoskeletal and signaling molecules. J. Cell Biol. 131, 791-805.
43. MONFERRAN, S., MULLER, C., MOUREY, L., FRIT, P., and SALLES, B. (2004). The membrane-associated form of the DNA repair protein Ku is involved in cell adhesion to fibronectin. J. Mol. Biol. 337, 503-511.
44. MOULD, A.P., TRAVIS, M.A., BARTON, S.J., HAMILTON, J.A., ASKARI, I.A., CRAIG, S.E., MACDONALD, P.R., KAMMERER, R.A., BUCKLEY, P.A., and HUMPHRIES, M.J. (2005). Evidence that monoclonal antibodies directed against the integrin β subunit plexin/semaphorin/integrin domain stimulate function by inducing receptor extension. J. Biol. Chem. 280, 4238-4246.
45. MUNAKATA, Y., SAITO-ITO, T., KUMURA-ISHII, K., HUANG, J., KODERA, T., ISHII, T., HIRABAYASHI, Y., KOYANAGI, Y., and SASAKI, T. (2005). Ku80 autoantigen as a cellular coreceptor for human parvovirus B19 infection. Blood 106, 3449-3456.
46. 3 initiate integrin signaling to the cytoskeleton. J. Cell Biol. 157, 265-275.
47. OZAWA, K., KURTZMAN, G., and YOUNG, N. (1986). Replication of the B19 parvovirus in human bone marrow cell cultures. Science 233, 883-886.
48. OZAWA, K., KURTZMAN, G., and YOUNG, N. (1987). Productive infection by B19 parvovirus of human erythroid bone marrow cells in vitro. Blood 70, 384-391.
49. 1, integrin site selectively regulates Akt/protein kinase B signaling via local activation of protein phosphatase 2A. J. Biol. Chem. 278, 18671-18681.
50. 3. J. Biol. Chem. 272, 2736-2743.
51. PONNAZHAGAN, S., WEIGEL, K.A., RAIKWAR, S.P., MUKHERJEE, P., YODER, M.C., and SRIVASTAVA, A. (1998). Recombinant human parvovirus B19 vectors: Erythroid cell-specific delivery and expression of transduced genes. J. Virol. 72, 5224-5230.
52. 1-mediated function. J. Cell Biol. 138, 1437-1447.
53. 2-integrin LFA-1. Blood 93, 107-112.
54. QING, K., MAH, C., HANSEN, J., ZHOU, S., DWARKI, V., and SRIVASTAVA, A. (1999). Human fibroblast growth factor receptor 1 is a co-receptor for infection by adeno-associated virus 2. Nat. Med. 5, 71-77.
55. RAPER, S.E., YUDKOFF, M., CHIRMULE, N., GAO, G.P., NUNES, F., HASKAL, Z.J., FURTH, E.E., PROPERT, K.J., ROBINSON, M.B., MAGOSIN, S., SIMOES, H., SPEICHER, L., HUGHES, J., TAZELAAR, J., WIVEL, N.A., WILSON, J.M., and BATSHAW, M.L. (2002). A pilot study of in vivo liver-directed gene transfer with an adenoviral vector in partial ornithine transcarbamylase deficiency. Hum. Gene Ther. 13, 163-175.
56. SHI, W., ARNOLD, G.S., and BARTLETT, J.S. (2001). Insertional mutagenesis of the adeno-associated virus type 2 (AAV2) capsid gene and generation of AAV2 vectors targeted to alternative cell-surface receptors. Hum. Gene Ther. 12, 1697-1711.
57. SRIVASTAVA, A. (2001). Parvovirus vectors for human gene therapy. Curr. Opin. Mol. Ther. 3, 491-496.
58. SRIVASTAVA, C.H., ZHOU, S., MUNSHI, N.C., and SRIVASTAVA, A. (1992). Parvovirus B19 replication in human umbilical cord blood cells. Virology 189, 456-461.
59. SUMMERFORD, C., and SAMULSKI, R.J. (1998). Membrane-associated heparan sulfate proteoglycan is a receptor for adeno-associated virus type 2 virions. J. Virol. 72, 1438-1445.
60. 5 integrin: A co-receptor for adeno-associated virus type 2 infection. Nat. Med. 5, 78-82.
61. TADOKORO, S., SHATTIL, S.J., ETO, K., TAI, V., LIDDINGTON, R.C., DE PEREDA, J.M., GINSBERG, M.H., and CALDERWOOD, D.A. (2003). Talin binding to integrin β tails: A final common step in integrin activation. Science 302, 103-106.
62. 3-mediated adhesion requires integrin conformational change and actin filament disassembly. J. Biol. Chem. 276, 14474-14481.
63. 1 integrin in vascular smooth muscle cells. Mol. Biol. Cell 9, 865-874.
64. WEIGEL-KELLEY, K.A., YODER, M.C., and SRIVASTAVA, A. (2001). Recombinant human parvovirus B19 vectors: Erythrocyte P antigen is necessary but not sufficient for successful transduction of human hematopoietic cells. J. Virol. 75, 4110-4116.
65. 1 integrin for viral entry. Blood 102, 3927-3933.
66. WILLIAMS, D.A., RIOS, M., STEPHENS, C., and PATEL, V.P. (1991). Fibronectin and VLA-4 in haematopoietic stem cell-microenvironment interactions. Nature 352, 438-441.
67. 1-integrin signaling pathway-mediated hematopoietic cell adhesion and migration. Blood 99, 2351-2359.
68. L-inserted domain. J. Biol. Chem. 280, 42207-42218.
69. ZHU, X., OHTSUBO, M., BOHMER, R.M., ROBERTS, J.M., and ASSOIAN, R.K. (1996). Adhesion-dependent cell cycle progression linked to the expression of cyclin D1, activation of cyclin E-cdk2, and phosphorylation of the retinoblastoma protein. J. Cell Biol. 133, 391-403.