ATP sensitivity of the ATP-sensitive K+ channel in intact and permeabilized pancreatic β-cells

Diabetes

Volumn 55, Issue 9, 2006, Pages 2446-2454

  Tarasov, Andrei I ^a   Girard, Christophe A J ^a   Ashcroft, Frances M ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

ATP i; ATP sm, submembrane ATP concentration; Intracellular concentration of ATP; KATP channel, ATP sensitive K + channel; LC CoA, long chain acyl CoA; NBD, nucleotide binding domain

Indexed keywords

ADENOSINE DERIVATIVE; ADENOSINE DIPHOSPHATE; ADENOSINE DIPHOSPHATE MAGNESIUM; ADENOSINE TRIPHOSPHATE MAGNESIUM; ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; ALPHA TOXIN; ENDOGENOUS COMPOUND; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR6.2; SULFONYLUREA RECEPTOR; ABC TRANSPORTER; ACYL COENZYME A; ADENOSINE TRIPHOSPHATE; BACTERIAL TOXIN; DRUG RECEPTOR; GLUCOSE; HEMOLYSIN; INWARDLY RECTIFYING POTASSIUM CHANNEL; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; POTASSIUM CHANNEL; STAPHYLOCOCCAL ALPHA-TOXIN; STAPHYLOCOCCUS ALPHA TOXIN;

ANIMAL CELL; ARTICLE; CELL MEMBRANE PERMEABILITY; CELL METABOLISM; CONTROLLED STUDY; ELECTRIC ACTIVITY; INSULIN RELEASE; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; ANIMAL; DRUG EFFECT; METABOLISM; PATCH CLAMP; PHYSIOLOGY;

ACYL COENZYME A; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BACTERIAL TOXINS; CELL MEMBRANE PERMEABILITY; GLUCOSE; HEMOLYSIN PROTEINS; INSULIN-SECRETING CELLS; MICE; PATCH-CLAMP TECHNIQUES; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; POTASSIUM CHANNELS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; RECEPTORS, DRUG;

EID: 33750600939     PISSN: 00121797     EISSN: 00121797     Source Type: Journal    
DOI: 10.2337/db06-0360     Document Type: Article

References (40)

1. Ashcroft FM, Rorsman P: Electrophysiology of the pancreatic beta-cell. Prog Biophys Mol Biol 54:87-143, 1989
2. Seino S, Miki T: Physiological and pathophysiological roles of ATP-sensitive K+ channels. Prog Biophys Mol Biol 81:133-176, 200 3
3. Dunne MJ, Cosgrove KE, Shepherd RM, Aynsley-Green A, Lindley KJ: Hyperinsulinism in infancy: from basic science to clinical disease. Physiol Rev 84:239-275, 2004
4. Ashcroft FM: ATP-sensitive potassium channelopathies: focus on insulin secretion. J Clin Invest 115:2047-2058, 200 5
5. Tucker SJ, Gribble FM, Zhao C, Trapp S, Ashcroft FM: Truncation of Kir6.2 produces ATP-sensitive K+ channels in the absence of the sulphonylurea receptor. Nature 387:179-183, 1997
6. Nichols CG, Lederer WJ: The regulation of ATP-sensitive K+ channel activity in intact and permeabilized rat ventricular myocytes. J Physiol 423:91-110, 1990
7. Shyng SL, Nichols CG: Membrane phospholipid control of nucleotide sensitivity of KATP channels. Science 282:1138-1141, 1998
8. Gribble FM, Proks P, Corkey BE, Ashcroft FM: Mechanism of cloned ATP-sensitive potassium channel activation by oleoyl-CoA. J Biol Chem 273:26383-26387, 1998
9. Kakei M, Kelly RP, Ashcroft SJ, Ashcroft FM: The ATP-sensitivity of K+ channels in rat pancreatic B-cells is modulated by ADP. FEBS Lett 208:63-66, 1986
10. Nichols CG, Shyng SL, Nestorowicz A, Glaser B, Clement JP 4th, Gonzalez G, Aguilar-Bryan L, Permutt MA, Bryan J: Adenosine diphosphate as an intracellular regulator of insulin secretion. Science 272:1785-1787, 1996
11. Kennedy HJ, Pouli AE, Ainscow EK, Jouaville LS, Rizzuto R, Rutter GA: Glucose generates sub-plasma membrane ATP microdomains in single islet beta-cells: potential role for strategically located mitochondria. J Biol Chem 274:13281-13291, 1999
12. Gribble FM, Loussouarn G, Tucker SJ, Zhao C, Nichols CG, Ashcroft FM: A novel method for measurement of submembrane ATP concentration. J Biol Chem 275:30046-30049, 2000
13. + channel: a pas de deux. Diabetes 53 (Suppl. 3):S113-S122, 2004
14. Sakura H, Ashcroft SJ, Terauchi Y, Kadowaki T, Ashcroft FM: Glucose modulation of ATP-sensitive K-currents in wild-type, homozygous and heterozygous glucokinase knock-out mice. Diabetologia 41:654-659, 1998
15. Tsuboi T, Lippiat JD, Ashcroft FM, Rutter GA: ATP-dependent interaction of the cytosolic domains of the inwardly rectifying K+ channel Kir6.2 revealed by fluorescence resonance energy transfer. Proc Natl Acad Sci U S A 101:76-81, 2004
16. Gribble FM, Tucker SJ, Ashcroft FM: The essential role of the Walker A motifs of SUR1 in K-ATP channel activation by Mg-ADP and diazoxide. Embo J 16:1145-1152, 1997
17. Qin F, Auerbach A, Sachs F: Estimating single-channel kinetic parameters from idealized patch-clamp data containing missed events. Biophys J 70:264-280, 1996
18. Zingman LV, Alekseev AE, Bienengraeber M, Hodgson D, Karger AB, Dzeja PP, Terzic A: Signaling in channel/enzyme multimers: ATPase transitions in SUR module gate ATP-sensitive K+ conductance. Neuron 31:233-245, 200 1
19. Dunne MJ, Findlay I, Petersen OH, Wollheim CB: ATP-sensitive K+ channels in an insulin-secreting cell line are inhibited by D-glyceraldehyde and activated by membrane permeabilization. J Membr Biol 93:271-279, 1986
20. Rosado JA, Sage SO: Phosphoinositides are required for store-mediated calcium entry in human platelets. J Biol Chem 275:9110-9113, 2000
21. Krippeit-Drews P, Backer M, Dufer M, Drews G: Phosphocreatine as a determinant of K(ATP) channel activity in pancreatic beta-cells. Pflugers Arch 445:556-562, 2003
22. Detimary P, Jonas JC, Henquin JC: Stable and diffusible pools of nucleotides in pancreatic islet cells. Endocrinology 137:4671-4676, 1996
23. Ghosh A, Ronner P, Cheong E, Khalid P, Matschinsky FM: The role of ATP and free ADP in metabolic coupling during fuel-stimulated insulin release from islet beta-cells in the isolated perfused rat pancreas. J Biol Chem 266:22887-22892, 1991
24. Erecinska M, Bryla J, Michalik M, Meglasson MD, Nelson D: Energy metabolism in islets of Langerhans. Biochim Biophys Acta 1101:273-295, 1992
25. Dabrowski M, Tarasov A, Ashcroft FM: Mapping the architecture of the ATP-binding site of the KATP channel subunit Kir6.2. J Physiol 557:347-354, 2004
26. Treiman M, Caspersen C, Christensen SB: A tool coming of age: thapsigargin as an inhibitor of sarco-endoplasmic reticulum Ca(2+)-ATPases. Trends Pharmacol Sci 19:131-135, 1998
27. Larsson O, Ammala C, Bokvist K, Fredholm B, Rorsman P: Stimulation of the KATP channel by ADP and diazoxide requires nucleotide hydrolysis in mouse pancreatic beta-cells. J Physiol 463:349-365, 1993
28. Nichols CG, Lederer WJ, Cannell MB: ATP dependence of KATP channel kinetics in isolated membrane patches from rat ventricle. Biophys J 60:1164-1177, 1991
29. Gopel S, Kanno T, Barg S, Galvanovskis J, Rorsman P: Voltage-gated and resting membrane currents recorded from B-cells in intact mouse pancreatic islets. J Physiol 521:717-728, 1999
30. Ueda K, Komine J, Matsuo M, Seino S, Amachi T: Cooperative binding of ATP and MgADP in the sulfonylurea receptor is modulated by glibenclamide. Proc Natl Acad Sci U S A 96:1268-1272, 1999
31. Crawford RM, Ranki HJ, Botting CH, Budas GR, Jovanovic A: Creatine kinase is physically associated with the cardiac ATP-sensitive K+ channel in vivo. FASEB J 16:102-104, 2002
32. Fan Z, Makielski JC: Anionic phospholipids activate ATP-sensitive potassium channels. J Biol Chem 272:5388-5395, 1997
33. Lin CW, Yan F, Shimamura S, Barg S, Shyng SL: Membrane phosphoinositides control insulin secretion through their effects on ATP-sensitive K+ channel activity. Diabetes 54:2852-2858, 2005
34. Schulze D, Krauter T, Fritzenschaft H, Soom M, Baukrowitz T: Phosphatidylinositol 4,5-bisphosphate (PIP2) modulation of ATP and pH sensitivity in Kir channels: a tale of an active and a silent PIP2 site in the N terminus. J Biol Chem 278:10500-10505, 2003
35. Ashcroft FM, Harrison DE, Ashcroft SJ: Glucose induces closure of single potassium channels in isolated rat pancreatic beta-cells. Nature 312:446-448, 1984
36. Gao Z, Konrad RJ, Collins H, Matschinsky FM, Rothenberg PL, Wolf BA: Wortmannin inhibits insulin secretion in pancreatic islets and β-TC3 cells independent of its inhibition of phosphatidylinositol 3-kinase. Diabetes 45:854-862, 1996
37. Zawalich WS, Tesz GJ, Zawalich KC: Inhibitors of phosphatidylinositol 3-kinase amplify insulin release from islets of lean but not obese mice. J Endocrinol 174:247-258, 2002
38. Henquin JC: ATP-sensitive K+ channels may control glucose-induced electrical activity in pancreatic B-cells. Biochem Biophys Res Commun 156:769-775, 1988
39. Cook DL, Satin LS, Ashford ML, Hales CN: ATP-sensitive K+ channels in pancreatic beta-cells: spare-channel hypothesis. Diabetes 37:495-498, 1988
40. Ashcroft F, Rorsman P: Type 2 diabetes mellitus: not quite exciting enough? Hum Mol Genet 13 (Spec. no. 1): R21-R31, 2004