Are absences truly generalized seizures or partial seizures originating from or predominantly involving the pre-motor areas? Some clinical and theoretical observations and their implications for seizure classification

Epilepsy Research

Volumn 70, Issue SUPPL.1, 2006, Pages 141-155

  Craiu, Dana ^a   Magureanu, Sanda ^a   van Emde Boas, Walter ^b  

^a CAROL DAVILA UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

^b STICHTING EPILEPSIE INSTELLINGEN NEDERLAND SEIN   (Netherlands)

Author keywords

Absence seizures; Classification.; Cortico thalamo cortical epilepsy; Generalized seizures

Indexed keywords

ABSENCE; ADOLESCENT; ARTICLE; CASE REPORT; CHILD; CLASSIFICATION; CONSCIOUSNESS; ELECTROENCEPHALOGRAPHY; FOCAL EPILEPSY; GENERALIZED EPILEPSY; HUMAN; MALE; PATHOPHYSIOLOGY; PHYSIOLOGY; VIDEORECORDING;

ADOLESCENT; CHILD; CONSCIOUSNESS; ELECTROENCEPHALOGRAPHY; EPILEPSIES, PARTIAL; EPILEPSY, ABSENCE; EPILEPSY, GENERALIZED; HUMANS; MALE; VIDEO RECORDING;

EID: 33750597746     PISSN: 09201211     EISSN: 18726844     Source Type: Journal    
DOI: 10.1016/j.eplepsyres.2005.11.018     Document Type: Article

References (58)

1. Avanzini, G., de Curtis, M., Marescaux, C., Panzica, F., Spreafico, R., Vergnes, M., 1992. Role of the thalamic reticular nucleus in the generation of rhythmic thalamo-cortical activities subserving spike and waves. J. Neural. Transm. (Suppl. 35), 85-95.
2. Bancaud, J., 1972. Mechanisms of cortical discharges in 'generalized' epilepsies in man. In: Petsche, H., Brazier, M.A.B. (Eds.), Synchronization of EEG Activity in Epilepsies. Springer, New York, pp. 368-381.
3. Bancaud, J., Talarach, J., 1992. Clinical semiology of frontal lobe seizures. In: Chauvel, P., Delgado-Escueta, A.V., Halgren, E., Bancaud, J. (Eds.), Frontal Lobe Seizures and Epilepsies. Raven Press, New York, Adv. Neurol. 57, 3-58.
4. Blume, W.T., Lüders, H.O., Mizrahi, E., Tassinari, C., van Emde Boas,W., Engel Jr., J., 2001. Glossary of descriptive terminology for ictal semiology: report of the ILAE task force on classification and terminology. Epilepsia 42, 1212-1218.
5. Buzsaki, G., 1991. The thalamic clock: emergent network properties. Neuroscience 41, 351-364.
6. Commission on Classification and Terminology of the International League Against Epilepsy, 1981. Proposal for a revised clinical and electroencephalographic classification of epileptic seizures. Epilepsia 22, 489-501.
7. Commission on Classification and Terminology of the International League Against Epilepsy, 1989. Proposal for a revised classification of epilepsies and epileptic syndromes. Epilepsia 30, 389-399.
8. Contreras, D., Destexhe, A., Sejnowski, T.J., Steriade, M., 1996. Control of spatiotemporal coherence of a thalamic oscillation by corticothalamic feedback. Science 274, 771-774.
9. Drinkenburg, W.H.I.M., Schuurmans, M.L.E.J., Coenen, A.M.L., Vossen, I.M.H., van Luijtelaar, E.L.J.M., 2003. Ictal stimulus processing during spike-wave discharges in genetic epileptic rats. Behav. Brain Res. 143, 141-146.
10. Duncan, J.S., 2004. Imaging idiopathic generalized epilepsy. Clin. EEG Neurosci. 35, 168-172.
11. Engel Jr., J., 2001. A proposed diagnostic scheme for people with epileptic seizures and with epilepsy: report of the ILAE task force on classification and terminology. Epilepsia 42, 796-803.
12. Fuentealba, P., Steriade, M., 2005. The reticular nucleus revisited: intrinsic and network properties of a thalamic pacemaker. Prog. Neurobiol. 75, 125-141.
13. Gibbs, F.A., Davis, H., Lennox, W.G., 1935. The electroencephalogram in epilepsy and in conditions of impaired consciousness. Arch. Neurol. Psychiatr. 34, 1133-1148.
14. Gibbs, F.A., Gibbs, E.L., 1952. Atlas of Electroencephalography, vol. 2: Epilepsy. Addison-Wesley, Cambridge, Mass.
15. Gloor, P., 1968. Generalized cortico-reticular epilepsies: some considerations on the pathophysiology of generalized bilaterally synchronous spike and wave discharge. Epilepsia 9, 249-263.
16. Holmes, M.D., Brown, M., Tucker, D.M., 2004. Are "generalized" seizures truly generalized? Evidence of localized mesial frontal and frontopolar discharges in absence. Epilepsia 45, 1568-1579.
17. Janz, D., 2004. Juvenile myoclonic epilepsy (Janz syndrome)-a frontal lobe epilepsy? Epilepsia 45 (Suppl. 3), 47.
18. Jasper, H.H., Droogleever Fortuyn, J., 1947. Experimental studies on the functional anatomy of petit mal epilepsy. Res. Publ. Assoc. Res. Nerv. Ment. Dis. 26, 272-298.
19. Jasper, H.H., Kershman, J., 1941. Electroencephalographic classification of the epilepsies. Arch. Neurol. Psychiatr. 45, 903-943.
20. Koepp, M.J., 2005. Focal structural abnormalities in generalised epilepsies. Epilepsia 45 (Suppl. 3), 47.
21. Leutmezer, F., Lurger, S., Baumgartner, C., 2002. Focal features in patients with idiopathic generalised epilepsy. Epilepsy Res. 50, 293-300.
22. Leutmezer, F., 2005. Focal EEG signs in generalised epilepsies. Epilepsia 45 (Suppl. 3), 46-47.
23. Loiseau, P., Panayiotopoulos, C.P., 2004. Childhood absence epilepsy: International League Against Epilepsy Website (http://www.epilepsy.org/): proposed diagnostic system for people with epileptic seizures and epilepsy. Section: syndromes.
24. Lombroso, C.T., 1997. ConsistentEEGfocalities detected in subjects with primary generalized epilepsies monitored for two decades. Epilepsia 38, 797-812.
25. Lüders, H., Lesser, R.P., Dinner, D.G., Morris III, H.H., 1984. Generalized epilepsies: a review. Cleve. Clin. Q. 51, 205-226.
26. Lüders, H., Acharya, J., Baumgartner, C., Benbadis, S., Bleasel, A., Burgess, R., Dinner, D.S., Ebner, A., Foldvary, N., Geller, E., Hamer, H., Holthausen, H., Kotagal, P., Morris FH., Meencke, H.J., Noachtar, S., Rosenow, F., Sakamoto, A., Steinhoff, B.J., Tuxhorn, I.,Wyllie, E., 1998. Semiological seizure classification. Epilepsia 39, 1006-1013.
27. Manning, J.P., Richards, D.A., Bowery, N.G., 2003. Pharmacology of absence epilepsy. Trends Pharmacol. Sci. 24, 542-549.
28. McCormick, D.A., Bal, T., 1997. Sleep and arousal: thalamocortical mechanisms. Ann. Rev. Neurosci. 20, 185-215.
29. Meencke, H.J., 1995. Pathological findings in childhood absence epilepsy. In: Duncan, J.S., Panayiotopoulos, C.P. (Eds.), Typical Absences and Related Epileptic Syndromes. Churchill, London, pp. 122-132.
30. Meencke, H.J., Janz, D., 1985. The significance of microdysgenesia in primary generalized epilepsy: an answer to the considerations of Lyon and Gastaut. Epilepsia 26, 368-371.
31. Meeren, H.K., Pijn, J.P., van Luijtelaar, E.L., Coenen, A.M., Lopes da Silva, F.H., 2002. Cortical focus drives widespread corticothalamic networks during spontaneous absence in rats. J. Neurosci. 22, 1480-1495.
32. Meeren, H.K., van Luijtelaar, E.L., Lopes da Silva, F.H., Coenen, A.M., 2005. Evolving concepts on the pathophysiology of absence seizures. The cortical focus theory. Arch. Neurol. 62, 371-376.
33. Morison, R.S., Dempsey, E.W., 1942. A study of thalamocortical relations. Am. J. Physiol. 135, 281-292.
34. Niedermeyer, E., 1972. The Generalized Epilepsies: A Clinical Electroencephalographical Study. Charles C. Thomas Publisher, Springfield.
35. Panayiotopoulos, C.P., 1997. Absence epilepsies. In: Engel, J.J., Pedley, T.A. (Eds.), Epilepsy: A Comprehensive Textbook. Lippincott-Raven, Philadelphia, pp. 2327-2346.
36. Panayiotopoulos, C.P., 1999. Benign Childhood Partial Seizures and Related Epileptic Syndromes. John Libbey, London, pp. 204-205.
37. Panayiotopoulos, C.P., 2002. Idiopathic generalized epilepsies. In: Panayiotopoulos, C.P. (Ed.), A Guide to Epileptic Syndromes and their Treatment. Bladon Medical Publishing, Oxford, pp. 114-160.
38. Panayiotopoulos, C.P., 2004. Typical absence seizures: International League Against Epilepsy Website (http://www.epilepsy.org/): proposed diagnostic system for people with epileptic seizures and epilepsy. Section: seizure types.
39. Panayiotopoulos, C.P., Obeid, T., Waheed, G., 1989. Differentiation of typical absence seizures in epileptic syndromes: a video EEG study of 224 seizures in 20 patients. Brain 112, 1039-1056.
40. Penfield,W., Jasper, H., 1954. Epilepsy and the Functional Anatomy of the Human Brain. Little Brown, Boston.
41. Penry, J.K., Porter, R.J., Dreifuss, F.E., 1975. Simultaneous recording of absence seizures with videotape and electroencephalography: a study of 374 seizures in 48 patients. Brain 98, 427- 440.
42. Roger, J., Bureau, M., 1992. Distinctive characteristics of frontal lobe epilepsy versus idiopathic generalized epilepsy. In: Chauvel, P., Delgado-Escueta, A.V., Halgren, E., Bancaud, J. (Eds.), Frontal Lobe Seizures and Epilepsies. Raven Press, New York, Adv. Neurol. 57, 399-410.
43. Salek-Haddadi, A., Lemieux, L., Merschhemke, M., Friston, K.J., Duncan, J.S., Fish, D.R., 2003. Functional magnetic resonance imaging of human absence seizures. Ann. Neurol. 53, 663-667.
44. Savic, I., Seitz, R.J., Pauli, S., 1998. Brain distortions in patients with primarily generalized tonic-clonic seizures. Epilepsia 39, 364-370.
45. Sharbrough, F., Chatrian, G.E., Lesser, R.P., 1991. American EEG Society guidelines for standard electrode position nomenclature. J. Clin. Neurophysiol. 8, 200-202.
46. Stefan, H., 1982. Epileptische Absencen. Studien zur Anfallsstructur, Pathophysiologie und zum klinischenVerlauf. Thieme, Stuttgart. Stefan, H., Carter Snead III, O., 1997. Absence seizures. In: Engel, J.J., Pedley, T.A. (Eds.), Epilepsy: A Comprehensive Textbook. Lippincott-Raven, Philadelphia, p. 570.
47. Steriade, M., 1999. Cellular substrates of brain rhythms. In: Niedermeyer, E., Lopes da Silva, F. (Eds.), Electroencephalogra phy; Basic Principles, Clinical Applications and Related Fields. William & Wilkins, Baltimore, pp. 28-75.
48. Steriade, M., Llinas, R.R., 1988. The functional states of the thalamus and the associated neuronal interplay. Physiol. Rev. 68, 649-742.
49. Steriade, M., Oakson, G., Diallo, A., 1976. Cortically elicited spikewave after discharges in thalamic neurons. Electroencephal. Clin. Neurophysiol. 41, 641-644.
50. Tenney, J.R., Marshall, P.C., King, J.A., Ferris, C.F., 2004. fMRI of generalized absence status epilepticus in conscious marmoset monkeys reveals corticothalamic activation. Epilepsia 45, 1240-1247.
51. Unterberger, I., 2005. Focal seizure semiology in generalised epilepsies. Epilepsia 45 (Suppl. 3), 46.
52. Unterberger, I., Trinka, E., Luef, G., Bauer, G., 2001. Idiopathic generalised epilepsies with pure Grand Mal: clinical data and genetics. Epilepsy Res. 44, 19-25.
53. Usui, N., Kotagal, P., Matsumoto, R., Kellinhaus, C., Lüders, H.O., 2005. Focal semiologic and electroencephalographic features in patients with juvenile myoclonic epilepsy. Epilepsia 46, 1668-1676.
54. vanEmdeBoas,W., Parra, J., Dekker, E., 2003. Continuing the debate on semiological versus conceptual seizure diagnosis and classification: why typical absence seizures should not be regarded as "generalised". Epilepsia 44 (Suppl. 8), 184.
55. van Emde Boas, W., Velis, D.N., 2000. Frontal lobe epilepsies. In: Vinken, P.J., Bruyn, G.W. (Eds.), Handbook of Clinical Neurology (revised series). In: Meinardi, H. (Ed.) The epilepsies, Part II, vol. 73, no. 29. Elsevier, Amsterdam, pp. 37-52.
56. Woermann, F.G., Sisodiya, S.M., Free, S.L., Duncan, J.S., 1998. Quantitative MRI in patients with idiopathic generalised epilepsy. Evidence of widespread cerebral structural changes. Brain 121, 1661-1667.
57. Woermann, F.G., Free, S.M., Koepp, M.J., Sisodiya, S.M., Duncan, J.S., 1999. Abnormal cerebral structure in juvenile myoclonic epilepsy demonstrated with voxel-based analysis of MRI. Brain 122, 2101-2108.
58. Yoshinaga, H., Ohtsuka, Y., Tamai, K., Ito, M., Ohmori, I., Oka, E., 2004. EEG in childhood absence epilepsy. Seizure 13, 296- 302.