The connecting tubule is the main site of the furosemide-induced urinary acidification by the vacuolar H+-ATPase

Kidney International

Volumn 70, Issue 10, 2006, Pages 1706-1716

  Kovacikova, J ^a   Winter, C ^a   Loffing Cueni, D ^b   Loffing, J ^b,c   Finberg, K E ^d   Lifton, R P ^d   Hummler, E ^b   Rossier, B ^b   Wagner, C A ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

^c UNIVERSITY OF FRIBOURG   (Switzerland)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Connecting tubule; Distal renal tubular acidosis (dRTA); Epithelial Na+ channel; Furosemide; H+ ATPase; Mouse

Indexed keywords

FUROSEMIDE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APICAL MEMBRANE; ARTICLE; CELL VACUOLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; KIDNEY ACIDIFYING CAPACITY; KIDNEY CLEARANCE; KIDNEY TUBULE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ACID-BASE EQUILIBRIUM; AMILORIDE; ANIMALS; DIURETICS; EPITHELIAL SODIUM CHANNEL; FUROSEMIDE; GENE EXPRESSION REGULATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HYDROCHLOROTHIAZIDE; HYDROGEN-ION CONCENTRATION; KIDNEY TUBULES, COLLECTING; KIDNEY TUBULES, DISTAL; METABOLIC CLEARANCE RATE; MICE; MICE, KNOCKOUT; NEPHRONS; PROTON-TRANSLOCATING ATPASES; WATER-ELECTROLYTE BALANCE;

EID: 33750593310     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/sj.ki.5001851     Document Type: Article

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