Visual exploratory behaviour in infancy and novelty seeking in adolescence: Two developmentally specific phenotypes of DRD4?

Journal of Child Psychology and Psychiatry and Allied Disciplines

Volumn 47, Issue 11, 2006, Pages 1143-1151

  Laucht, Manfred ^a   Becker, Katja ^a   Schmidt, Martin H ^a  

^a CENTRAL INSTITUTE OF MENTAL HEALTH   (Germany)

Author keywords

Adolescence; Dopamine D4 receptor gene; Infancy; Novelty seeking; Visual attention

Indexed keywords

DOPAMINE 4 RECEPTOR; GENOMIC DNA;

ADOLESCENT; AGE; ARTICLE; ATTENTION; CHILD BEHAVIOR; CHILD DEVELOPMENT; CONTROLLED STUDY; EXON; EXPLORATORY BEHAVIOR; FEMALE; GENETIC POLYMORPHISM; GENOTYPE; HABITUATION; HETEROZYGOTE; HUMAN; LONGITUDINAL STUDY; MALE; PHENOTYPE; PROSPECTIVE STUDY; PROTEIN FUNCTION; SEX DIFFERENCE;

ADOLESCENT; ALLELES; AROUSAL; CHILD; CHILD, PRESCHOOL; EXONS; EXPLORATORY BEHAVIOR; FEMALE; GENOTYPE; HUMANS; INFANT; INFANT, NEWBORN; INFANT, PREMATURE, DISEASES; LONGITUDINAL STUDIES; MALE; PHENOTYPE; POLYMORPHISM, GENETIC; PROSPECTIVE STUDIES; RECEPTORS, DOPAMINE D4; RISK FACTORS; SOCIAL ENVIRONMENT; VISUAL PERCEPTION;

EID: 33750517761     PISSN: 00219630     EISSN: 14697610     Source Type: Journal    
DOI: 10.1111/j.1469-7610.2006.01627.x     Document Type: Article

References (44)

1. Ainsworth, M.D. (1979). Infant-mother attachment. American Journal of Psychology, 34, 932-937.
2. Auerbach, J.G., Faroy, M., Ebstein, R., Kahana, M., & Levine, J. (2001a). The association of the dopamine D4 receptor gene (DRD4) and the serotonin transporter promoter gene (5-HTTLPR) with temperament in 12-month-old infants. Journal of Child Psychology and Psychiatry, 42, 777-783.
3. Auerbach, J.G., Benjamin, J., Faroy, M., Geller, V., & Ebstein, R. (2001b). DRD4 related to infant attention and information processing: A developmental link to ADHD ? Psychiatric Genetics, 11, 31-35.
4. Becker, K., Laucht, M., El-Faddagh, M., & Schmidt, M.H. (2005). The dopamine D4 receptor gene exon III polymorphism is associated with novelty seeking in 15-year-old males from a high risk community sample. Journal of Neural Transmission, 112, 857-858.
5. Benjamin, J., Lin, L., Patterson, C., Greenberg, B.D., Murphy, D.L., & Hamer, D.H. (1996). Population and familial association between the D4 dopamine receptor gene and measures of novelty seeking. Nature Genetics, 12, 81-84.
6. Bornstein, M., & Benasich, A. (1986). Infant habituation: Assessment of individual differences and short-term reliability at five months. Child Development, 57, 87-99.
7. Bornstein, M., & Sigman, M.D. (1986). Continuity in mental development from infancy. Child Development, 57, 251-274.
8. Brazelton, T.B., & Nugent, J.K. (1995). Neonatal Assessment Scale (3rd edn). London: MacKeith Press.
9. Chang, F.M., Kidd, J.R., Livak, K.J., Pakstis, A.J., & Kidd, K.K. (1996). The world-wide distribution of allele frequencies at the human dopamine D4 receptor locus. Human Genetics, 98, 91-101.
10. Cloninger, C.R. (1987). A systematic method for clinical description and classification of personality variants: A proposal. Archives of General Psychiatry, 44, 573-588.
11. Cloninger, C.R., Svrarkic, D.M., & Przybeck, T.R. (1993). A psychobiological model of temperament and character. Archives of General Psychiatry, 50, 975-990.
12. Collaer, M.L., & Hines, M. (1995). Human behavioral sex differences: A role for gonadal hormones during early development ? Psychological Bulletin, 118, 55-107.
13. Constantino, J.N., Cloninger, C.R., Clarke, A.R., Hashemi, B., & Przybeck, T. (2002). Application of the seven-factor model of personality to early childhood. Psychiatry Research 109, 229-243.
14. De Luca, A., Rizzardi, M., Buccino, A., Allessandroni, R., Salvioli, G.P., Filograsso, N., Novelli, G., & Dallapiccola, B. (2003). Association of dopamine D4 receptor (DRD4) exon III repeat polymorphism with temperament in 3-year-old infants. Neurogenetics, 4, 207-212.
15. Dulawa, S.C., Grandy, D.K., Low, M.J., Paulus, M.P., & Geyer, M.A. (1999). Dopamine D4 receptor-knock-out mice exhibit reduced exploration of novel stimuli. Journal of Neuroscience, 19, 9550-9556.
16. Ebstein, R.P., Novick, O., Umansky, R., Priel, B., Osher, Y., Blaine, D., Bennett, E.R., Nemanov, L., Katz, M., & Belmaker, R.H. (1996). Dopamine D4 receptor (DRD4) exon III polymorphism associated with the human personality trait of novelty seeking. Nature Genetics, 12, 78-80.
17. Ebstein, R.P., Levine, J., Geller, V., Auerbach, J., Gritsenko, I., & Belmaker, R.H. (1998). Dopamine D4 receptor and serotonin transporter promoter in the determination of neonatal temperament. Molecular Psychiatry, 3, 238-246.
18. Eley, T.C., & Craig, I.W. (2005). Introductory guide to the language of molecular genetics. Journal of Child Psychology and Psychiatry, 46, 1039-1041.
19. Faraone, S.V., Doyle, A.E., Mick, E., & Biederman, J. (2001). Meta-analysis of the association between the 7 repeat allele of the dopamine D4 receptor gene and attention deficit hyperactivity disorder. American Journal of Psychiatry, 158, 1052-1057.
20. Keenan, K., & Shaw, D. (1997). Developmental and social influences on young girls'early problem behavior. Psychological Bulletin, 121, 95-113.
21. Kluger, A.N., Siegfried, Z., & Ebstein, R.P. (2002). A meta-analysis of the association between DRD4 polymorphism and novelty seeking. Molecular Psychiatry, 7, 712-717.
22. Kudielka, B.M., & Kirschbaum, C. (2005). Sex differences in HPA axis responses to stress: A review. Biological Psychology, 69, 113-132.
23. Lakatos, K., Nemoda, Z., Birkas, E., Ronai, Z., Kovacs, E., Ney, K., Toth, I., Sasvari-Szekely, M., & Gervai, J. (2003). Association of D4 dopamine receptor gene and serotonin transporter promoter polymorphisms with infants'response to novelty. Molecular Psychiatry, 8, 90-97.
24. Laucht, M., Esser, G., & Schmidt, M.H. (1994). Contrasting infant predictors of later cognitive functioning. Journal of Child Psychology and Psychiatry, 35, 649-662.
25. Laucht, M., Esser, G., Schmidt, M.H., Baving, L., Gerhold, M., Hoesch, I., Ihle, W., Steigleider, P., Stock, B., Stöhr, R.M., & Weindrich, D. (2000). Behavioral sequelae of perinatal insults and early family adversity at 8years of age. Journal of the American Academy of Child and Adolescent Psychiatry, 39, 1229-1237.
26. Laucht, M., Becker, K., El-Faddagh, M., Hohm, E., & Schmidt, M.H. (2005). Association of the DRD4 exon III polymorphism with smoking in 15-year-olds: A mediating role for novelty seeking ? Journal of the American Academy of Child and Adolescent Psychiatry, 44, 477-484.
27. Lee, H.J., Lee, H.S., Kim, Y.K., Kim, S.H., Kim, L., Lee, M.S., Joe, S.H., Jung, I.K., Suh, K.Y., & Kim, S. (2003). Allelic variants interaction of dopamine receptor D4 polymorphism correlate with personality traits in young Korean female population. American Journal of Medical Genetics B Neuropsychiatric Genetics, 118, 76-80.
28. Lewis, M., & Brooks-Gunn, J. (1981). Visual attention at three months as a predictor of cognitive functioning at two years of age. Intelligence, 5, 131-140.
29. Lichter, J.B., Barr, C.L., Kennedy, J.L., Van Tol, H.H., Kidd, K.K., & Livak, K.J. (1993). A hypervariable segment on the human dopamine receptor D4 (DRD4) gene. Human Molecular Genetics, 2, 767-773.
30. Lynn, D.E., Lubke, G., Yang, M., McCracken, J.T., McGough, J.J., Ishii, J., Loo, S.K., Nelson, S.F., & Smalley, S.L. (2005). Temperament and character profiles and the dopamine D4 receptor gene in ADHD. American Journal of Psychiatry, 162, 906-913.
31. Lyons, M.J., True, W.R., Eisen, S.A., Goldberg, J., Meyer, J.M., Faraone, S.V., Eaves, L.J., & Tsuang, M.T. (1995). Differential heritability of adult and juvenile antisocial traits. Archives of General Psychiatry, 52, 906-915.
32. Malhotra, A.K., Virkkunen, M., Rooney, W., Eggert, M., Linnoila, M., & Goldman, D. (1996). The association between the dopamine D4 receptor (D4DR) 16 amino acid repeat polymorphism and novelty seeking. Molecular Psychiatry, 1, 388-391.
33. McCall, R.B., & Carriger, R. (1993). A meta-analysis of infant habituation and recognition memory performance as predictors of later IQ. Child Development, 64, 57-79.
34. Plomin, R., & Rutter, M. (1998). Child development, molecular genetics, and what to do with genes once they are found. Child Development, 69, 1223-1242.
35. Reiss, D., & Neiderhiser, J.M. (2000). The interplay of genetic influences and social processes in developmental theory: Specific mechanisms are coming into view. Development and Psychopathology, 12, 357-374.
36. Rende, R., & Plomin, R. (1995). Nature, nurture, and the development of psychopathology. In D. Cicchetti & D.J. Cohen (Eds.), Developmental psychopathology Vol. 1 Theory and methods (pp. 291-314). New York: Wiley.
37. Rettew, D.C., Copeland, W., Stanger, C., & Hudziak, J.J. (2004). Associations between temperament and DSM-IV externalizing disorders in children and adolescents. Journal of Developmental and Behavioral Pediatrics, 25, 383-391.
38. Rutter, M., Caspi, A., & Moffitt, T.E. (2003). Using sex differences in psychopathology to study causal mechanisms: Unifying issues and research strategies. Journal of Child Psychology and Psychiatry, 44, 1092-1115.
39. Schmeck, K., Goth, K., Cloninger, R.C., & Poustka, F. (2001). Reliability and validity of the Junior Temperament and Character Inventory. International Journal of Methods in Psychiatric Research, 10, 172-182.
40. Slater, A. (1988). Habituation and visual fixation in infants: Information processing, reinforcement, and what else ? European Bulletin of Cognitive Psychology, 8, 517-523.
41. Swanson, J.M., Flodman, P., Kennedy, J., Spence, M.A., Moyzis, R., Schuck, S., Murias, M., Moriarity, J., Barr, C., Smith, M., & Posner, M. (2000). Dopamine genes and ADHD. Neuroscience and Biobehavioral Reviews, 24, 21-25.
42. Taylor, S.E., Klein, L.C., Lewis, B.P., Gruenewald, T.L., Gurung, R.A., & Updegraff, J.A. (2000). Biobehavioral responses to stress in females: Tend-and-befriend, not fight-or-flight. Psychology Review, 107, 411-429.
43. Tillman, R., Geller, B., Craney, J.L., Bolhofner, K., Williams, M., Zimerman, B., Frazier, J., & Beringer, L. (2003). Temperament and character factors in a prepubertal and early adolescent bipolar disorder phenotype compared to attention deficit hyperactive and normal controls. Journal of Child and Adolescent Psychopharmacology, 13, 531-543.
44. Zuckerman, M., & Kuhlman, D.M. (2000). Personality and risk-taking: Common biosocial factors. Journal of Personality, 68, 999-1029.