-
1
-
-
0001829308
-
Dexmedetomidine: a novel sedative-analgesic agent
-
Gertler R., Brown H.C., Mitchell D.H., et al. Dexmedetomidine: a novel sedative-analgesic agent. BUMC Proceedings 14 (2001) 13-21
-
(2001)
BUMC Proceedings
, vol.14
, pp. 13-21
-
-
Gertler, R.1
Brown, H.C.2
Mitchell, D.H.3
-
2
-
-
0023903938
-
Characterization of the selectivity, specificity and potency of medetomidine as an alpha 2-adrenoceptor agonist
-
Virtanen R., Sawvola J.M., Saano V., et al. Characterization of the selectivity, specificity and potency of medetomidine as an alpha 2-adrenoceptor agonist. Eur J Pharmacol 150 (1988) 9-14
-
(1988)
Eur J Pharmacol
, vol.150
, pp. 9-14
-
-
Virtanen, R.1
Sawvola, J.M.2
Saano, V.3
-
3
-
-
0025812831
-
The effect of intravenously administered dexmedetomidine on perioperative hemodynamics and isolflurane requirements in patients undergoing abdominal hysterectomy
-
Aho M., Lehtinen A.M., Erkola O., et al. The effect of intravenously administered dexmedetomidine on perioperative hemodynamics and isolflurane requirements in patients undergoing abdominal hysterectomy. Anesthesiology 74 (1991) 997-1002
-
(1991)
Anesthesiology
, vol.74
, pp. 997-1002
-
-
Aho, M.1
Lehtinen, A.M.2
Erkola, O.3
-
4
-
-
0025045928
-
Dexmedetomidine, an alpha 2 adrenergic agonist, reduces anesthetic requirements for patients undergoing minor gynecological surgery
-
Aantaa R., Kanto J., Scheinin M., et al. Dexmedetomidine, an alpha 2 adrenergic agonist, reduces anesthetic requirements for patients undergoing minor gynecological surgery. Anesthesiology 73 (1990) 230-235
-
(1990)
Anesthesiology
, vol.73
, pp. 230-235
-
-
Aantaa, R.1
Kanto, J.2
Scheinin, M.3
-
5
-
-
0026453542
-
Intramuscularly administered dexmedetomidine attenuates hemodynamic and stress hormone responses to gynecologic laparoscopy
-
Aho M., Scheinin M., Lehtinen A.M., et al. Intramuscularly administered dexmedetomidine attenuates hemodynamic and stress hormone responses to gynecologic laparoscopy. Anesth Analg 75 (1992) 932-939
-
(1992)
Anesth Analg
, vol.75
, pp. 932-939
-
-
Aho, M.1
Scheinin, M.2
Lehtinen, A.M.3
-
6
-
-
0026559744
-
Circuitary linking opioid-sensitive nociceptive modulatory systems in periaque-ductal gray and spinal cord with rostral ventromedidal medulla
-
Morgan M., Heinricher M., and Fields H. Circuitary linking opioid-sensitive nociceptive modulatory systems in periaque-ductal gray and spinal cord with rostral ventromedidal medulla. Neuroscience 47 (1992) 863-871
-
(1992)
Neuroscience
, vol.47
, pp. 863-871
-
-
Morgan, M.1
Heinricher, M.2
Fields, H.3
-
7
-
-
0026621830
-
Effects of intravenous dexmedetomidine in humans. I. Sedation, ventilation, and metabolic rate
-
Belleville J.P., Ward D.S., Bloor B.C., et al. Effects of intravenous dexmedetomidine in humans. I. Sedation, ventilation, and metabolic rate. Anesthesiology 77 (1992) 1125-1133
-
(1992)
Anesthesiology
, vol.77
, pp. 1125-1133
-
-
Belleville, J.P.1
Ward, D.S.2
Bloor, B.C.3
-
8
-
-
0032855010
-
Effects of dexmedetomidine on isoflurane requirements in healthy volunteers. I: Pharmacodynamic and pharmacokinetic interactions
-
Khan Z.P., Munday I.T., Jones R.M., et al. Effects of dexmedetomidine on isoflurane requirements in healthy volunteers. I: Pharmacodynamic and pharmacokinetic interactions. Br J Anaesth 83 (1999) 372-380
-
(1999)
Br J Anaesth
, vol.83
, pp. 372-380
-
-
Khan, Z.P.1
Munday, I.T.2
Jones, R.M.3
-
9
-
-
0032851811
-
Effect of dexmedetomidine on the minimum alveolar concentration (MAC) of sevoflurane in adults age 55 to 70 years
-
Fragen R., and Fitzgerald P. Effect of dexmedetomidine on the minimum alveolar concentration (MAC) of sevoflurane in adults age 55 to 70 years. J Clin Anesth 11 (1999) 466-470
-
(1999)
J Clin Anesth
, vol.11
, pp. 466-470
-
-
Fragen, R.1
Fitzgerald, P.2
-
10
-
-
0026570660
-
Dexmedetomidine attenuates sympathoadrenal responses to tracheal intubation and reduces the need for thiopentone and perioperative fentanyl
-
Scheinin B., Lundgren L., Randell T., et al. Dexmedetomidine attenuates sympathoadrenal responses to tracheal intubation and reduces the need for thiopentone and perioperative fentanyl. Br J Anaesth 68 (1992) 126-131
-
(1992)
Br J Anaesth
, vol.68
, pp. 126-131
-
-
Scheinin, B.1
Lundgren, L.2
Randell, T.3
-
11
-
-
0000182053
-
Dexmedetomidine pharmacokinetics and pharmacodynamics
-
Dyck J., and Shafer S. Dexmedetomidine pharmacokinetics and pharmacodynamics. Anaesth Pharm Review 1 (1993) 238-245
-
(1993)
Anaesth Pharm Review
, vol.1
, pp. 238-245
-
-
Dyck, J.1
Shafer, S.2
-
12
-
-
0032905215
-
Alpha-2 and imidazoline receptor agonists: their pharmacology and therapeutic role
-
Khan Z.P., Ferguson C.N., and Jones R.M. Alpha-2 and imidazoline receptor agonists: their pharmacology and therapeutic role. Anaesthesia 54 2 (1999) 146-165
-
(1999)
Anaesthesia
, vol.54
, Issue.2
, pp. 146-165
-
-
Khan, Z.P.1
Ferguson, C.N.2
Jones, R.M.3
-
13
-
-
0142094416
-
The role of the alpha2-adrenoceptor agonist dexmedetomidine in postsurgical sedation in the intensive care unit
-
Martin E., Ramay G., Mantz J., et al. The role of the alpha2-adrenoceptor agonist dexmedetomidine in postsurgical sedation in the intensive care unit. J Intensive Care Med 18 1 (2003) 29-41
-
(2003)
J Intensive Care Med
, vol.18
, Issue.1
, pp. 29-41
-
-
Martin, E.1
Ramay, G.2
Mantz, J.3
-
14
-
-
0036257713
-
Pharmacokinetics of dexmedetomidine infusions for sedation of postoperative patients requiring intensive care
-
Venn R.M., Karol M.D., and Grounds R.M. Pharmacokinetics of dexmedetomidine infusions for sedation of postoperative patients requiring intensive care. Br J Anaesth 88 5 (2002) 669-675
-
(2002)
Br J Anaesth
, vol.88
, Issue.5
, pp. 669-675
-
-
Venn, R.M.1
Karol, M.D.2
Grounds, R.M.3
-
15
-
-
11444253457
-
Dexmedetomidine infusion without loading dose in surgical patients requiring mechanical ventilation: haemodynamic effects and efficacy
-
Ickeringill M., Shehabi Y., Adamson H., et al. Dexmedetomidine infusion without loading dose in surgical patients requiring mechanical ventilation: haemodynamic effects and efficacy. Anaesth Intensive Care 32 6 (2004) 741-745
-
(2004)
Anaesth Intensive Care
, vol.32
, Issue.6
, pp. 741-745
-
-
Ickeringill, M.1
Shehabi, Y.2
Adamson, H.3
-
16
-
-
16544394473
-
Dexmedetomidine and asystole
-
[author reply: 1479-80]
-
Videira R.L., and Ferreira R.M. Dexmedetomidine and asystole. Anesthesiology 101 6 (2004) 1479 [author reply: 1479-80]
-
(2004)
Anesthesiology
, vol.101
, Issue.6
, pp. 1479
-
-
Videira, R.L.1
Ferreira, R.M.2
-
17
-
-
21744433546
-
From the FDA: what's in a Label? A guide for the anesthesia practitioner
-
Chang N.S., Simone A.F., and Schultheis L.W. From the FDA: what's in a Label? A guide for the anesthesia practitioner. Anesthesiology 103 1 (2005) 179-185
-
(2005)
Anesthesiology
, vol.103
, Issue.1
, pp. 179-185
-
-
Chang, N.S.1
Simone, A.F.2
Schultheis, L.W.3
-
18
-
-
8444241155
-
The impact of unlicensed and off-label drug use on adverse drug reactions in paediatric patients
-
Neubert A., Dormann H., Weiss J., et al. The impact of unlicensed and off-label drug use on adverse drug reactions in paediatric patients. Drug Saf 27 13 (2004) 1059-1067
-
(2004)
Drug Saf
, vol.27
, Issue.13
, pp. 1059-1067
-
-
Neubert, A.1
Dormann, H.2
Weiss, J.3
-
19
-
-
20244368931
-
Survey of unlicensed and off label drug use in paediatric wards in European countries: European Network for Drug Investigation in Children
-
Conroy S., Choonara I., Impicciatore P., et al. Survey of unlicensed and off label drug use in paediatric wards in European countries: European Network for Drug Investigation in Children. BMJ 320 7227 (2000) 79-82
-
(2000)
BMJ
, vol.320
, Issue.7227
, pp. 79-82
-
-
Conroy, S.1
Choonara, I.2
Impicciatore, P.3
-
20
-
-
2342465509
-
Unlicensed and off-label drug use in children: implications for safety
-
Choonara I. Unlicensed and off-label drug use in children: implications for safety. Expert Opin Drug Saf 3 2 (2004) 81-83
-
(2004)
Expert Opin Drug Saf
, vol.3
, Issue.2
, pp. 81-83
-
-
Choonara, I.1
-
21
-
-
0037635309
-
Paediatric medicines research in the UK: how to move forward?
-
Wong I., Sweis D., Cope J., et al. Paediatric medicines research in the UK: how to move forward?. Drug Saf 26 8 (2003) 529-537
-
(2003)
Drug Saf
, vol.26
, Issue.8
, pp. 529-537
-
-
Wong, I.1
Sweis, D.2
Cope, J.3
-
22
-
-
0032128793
-
FDA proposes new rules for off-label use of prescription drugs. Food and Drug Administration
-
Baker R. FDA proposes new rules for off-label use of prescription drugs. Food and Drug Administration. BETA July (1998) 8-9
-
(1998)
BETA
, vol.July
, pp. 8-9
-
-
Baker, R.1
-
23
-
-
13244268470
-
Off license and off label prescribing in children: litigation fears for physicians
-
Hill P. Off license and off label prescribing in children: litigation fears for physicians. Arch Dis Child 90 Suppl 1 (2005) i17-i18
-
(2005)
Arch Dis Child
, vol.90
, Issue.SUPPL. 1
-
-
Hill, P.1
-
24
-
-
0036166695
-
Initial experience with dexmedetomidine in paediatric-aged patients
-
Tobias J.D., and Berkenbosch J.W. Initial experience with dexmedetomidine in paediatric-aged patients. Paediatr Anaesth 12 2 (2002) 171-175
-
(2002)
Paediatr Anaesth
, vol.12
, Issue.2
, pp. 171-175
-
-
Tobias, J.D.1
Berkenbosch, J.W.2
-
25
-
-
18044387383
-
Adverse events associated with sedatives, analgesics, and other drugs that provide patient comfort in the intensive care unit
-
Riker R.R., and Fraser G.L. Adverse events associated with sedatives, analgesics, and other drugs that provide patient comfort in the intensive care unit. Pharmacotherapy 25 5 Pt 2 (2005) 8S-18S
-
(2005)
Pharmacotherapy
, vol.25
, Issue.5 PART 2
-
-
Riker, R.R.1
Fraser, G.L.2
-
26
-
-
20844460961
-
Addition of dexmedetomidine to lidocaine for intravenous regional anaesthesia
-
Esmaoglu A., Mizrak A., Akin A., et al. Addition of dexmedetomidine to lidocaine for intravenous regional anaesthesia. Eur J Anaesthesiol 22 6 (2005) 447-451
-
(2005)
Eur J Anaesthesiol
, vol.22
, Issue.6
, pp. 447-451
-
-
Esmaoglu, A.1
Mizrak, A.2
Akin, A.3
-
27
-
-
18044371429
-
Dexmedetomidine and awake fiberoptic intubation for possible cervical spine myelopathy: a clinical series
-
Avitsian R., Li J., Jain U., et al. Dexmedetomidine and awake fiberoptic intubation for possible cervical spine myelopathy: a clinical series. J Neurosurg Anesthesiol 17 2 (2005) 97-99
-
(2005)
J Neurosurg Anesthesiol
, vol.17
, Issue.2
, pp. 97-99
-
-
Avitsian, R.1
Li, J.2
Jain, U.3
-
28
-
-
0028918142
-
Effects of perioperative dexmedetomidine infusion in patients undergoing vascular surgery: the Study of Perioperative Ischemia Research Group
-
Talke P., Chen R., Thomas B., et al. Effects of perioperative dexmedetomidine infusion in patients undergoing vascular surgery: the Study of Perioperative Ischemia Research Group. Anesthesiology 82 (1995) 620-633
-
(1995)
Anesthesiology
, vol.82
, pp. 620-633
-
-
Talke, P.1
Chen, R.2
Thomas, B.3
-
29
-
-
0034125510
-
The hemodynamic and adrenergic effects of perioperative dexmedetomidine infusion after vascular surgery
-
Talke P., Chen R., Thomas B., et al. The hemodynamic and adrenergic effects of perioperative dexmedetomidine infusion after vascular surgery. Anesth Analg 90 (2000) 834-839
-
(2000)
Anesth Analg
, vol.90
, pp. 834-839
-
-
Talke, P.1
Chen, R.2
Thomas, B.3
-
30
-
-
25844508406
-
A prospective, double-blind, randomized, placebo-controlled study of dexmedetomidine as an adjunct to epidural analgesia after thoracic surgery
-
Wahlander S., Frumento R.J., Wagener G., et al. A prospective, double-blind, randomized, placebo-controlled study of dexmedetomidine as an adjunct to epidural analgesia after thoracic surgery. J Cardiothorac Vasc Anesth 19 5 (2005) 630-635
-
(2005)
J Cardiothorac Vasc Anesth
, vol.19
, Issue.5
, pp. 630-635
-
-
Wahlander, S.1
Frumento, R.J.2
Wagener, G.3
-
31
-
-
0346962993
-
Dexmedetomidine and neurocognitive testing in awake craniotomy
-
Mack P.F., Perrine K., Kobylanz E., et al. Dexmedetomidine and neurocognitive testing in awake craniotomy. J Neurosurg Anesthesiol 16 1 (2004) 20-25
-
(2004)
J Neurosurg Anesthesiol
, vol.16
, Issue.1
, pp. 20-25
-
-
Mack, P.F.1
Perrine, K.2
Kobylanz, E.3
-
32
-
-
0027510650
-
Dexmedetomidine decreases cerebral blood flow velocity in humans
-
Zornow M.H., Maze M., Dyek J.B., et al. Dexmedetomidine decreases cerebral blood flow velocity in humans. J Cereb Blood Flow Metab 13 (1993) 350-353
-
(1993)
J Cereb Blood Flow Metab
, vol.13
, pp. 350-353
-
-
Zornow, M.H.1
Maze, M.2
Dyek, J.B.3
-
33
-
-
0032876215
-
Effects of dexmedetomidine on isoflurane requirements in healthy volunteers. II: Auditory and somatosensory evoked responses
-
Thornton C., Lucas M.A., Newton D.E., et al. Effects of dexmedetomidine on isoflurane requirements in healthy volunteers. II: Auditory and somatosensory evoked responses. Br J Anaesth 83 3 (1999) 381-386
-
(1999)
Br J Anaesth
, vol.83
, Issue.3
, pp. 381-386
-
-
Thornton, C.1
Lucas, M.A.2
Newton, D.E.3
-
34
-
-
0642335955
-
Additional experience with dexmedetomidine in pediatric patients
-
Tobias J.D., Berkenbosch J.W., and Russo P. Additional experience with dexmedetomidine in pediatric patients. South Med J 96 9 (2003) 871-875
-
(2003)
South Med J
, vol.96
, Issue.9
, pp. 871-875
-
-
Tobias, J.D.1
Berkenbosch, J.W.2
Russo, P.3
-
35
-
-
0025306657
-
General anesthesia prior to treatment of anterior mediastinal masses in pediatric cancer patients
-
Ferrari L.R., and Bedford R.F. General anesthesia prior to treatment of anterior mediastinal masses in pediatric cancer patients. Anesthesiology 72 6 (1990) 991-995
-
(1990)
Anesthesiology
, vol.72
, Issue.6
, pp. 991-995
-
-
Ferrari, L.R.1
Bedford, R.F.2
-
36
-
-
24144493670
-
Collapsibility of the upper airway at different concentrations of propofol anesthesia
-
Eastwood P.R., Platt P.R., Shepherd K., et al. Collapsibility of the upper airway at different concentrations of propofol anesthesia. Anesthesiology 103 3 (2005) 470-477
-
(2005)
Anesthesiology
, vol.103
, Issue.3
, pp. 470-477
-
-
Eastwood, P.R.1
Platt, P.R.2
Shepherd, K.3
-
37
-
-
0029019910
-
Dexmedetomidine premedication attenuates ketamine-induced cardiostimulatory effects and postanesthetic delirium
-
Levanen J., Makela M.L., and Scheinin H. Dexmedetomidine premedication attenuates ketamine-induced cardiostimulatory effects and postanesthetic delirium. Anesthesiology 82 5 (1995) 1117-1125
-
(1995)
Anesthesiology
, vol.82
, Issue.5
, pp. 1117-1125
-
-
Levanen, J.1
Makela, M.L.2
Scheinin, H.3
-
38
-
-
14944369631
-
Rescue sedation with dexmedetomidine for diagnostic imaging: a preliminary report
-
Nichols D.P., Berkenbosch J.W., and Tobias J.D. Rescue sedation with dexmedetomidine for diagnostic imaging: a preliminary report. Paediatr Anaesth 15 3 (2005) 199-203
-
(2005)
Paediatr Anaesth
, vol.15
, Issue.3
, pp. 199-203
-
-
Nichols, D.P.1
Berkenbosch, J.W.2
Tobias, J.D.3
-
39
-
-
19944386258
-
Sedative, haemodynamic and respiratory effects of dexmedetomidine in children undergoing magnetic resonance imaging examination: preliminary results
-
Koroglu A., Demirbileks S., Teksan H., et al. Sedative, haemodynamic and respiratory effects of dexmedetomidine in children undergoing magnetic resonance imaging examination: preliminary results. Br J Anaesth 94 6 (2005) 821-824
-
(2005)
Br J Anaesth
, vol.94
, Issue.6
, pp. 821-824
-
-
Koroglu, A.1
Demirbileks, S.2
Teksan, H.3
-
40
-
-
3042645548
-
Comparing dexmedetomidine prescribing patterns and safety in the naturalistic setting versus published data
-
Dasta J.F., Kane-Gill S.L., and Durtschi A.J. Comparing dexmedetomidine prescribing patterns and safety in the naturalistic setting versus published data. Ann Pharmacother 38 7-8 (2004) 1130-1135
-
(2004)
Ann Pharmacother
, vol.38
, Issue.7-8
, pp. 1130-1135
-
-
Dasta, J.F.1
Kane-Gill, S.L.2
Durtschi, A.J.3
-
41
-
-
0026677968
-
Effects of intravenous dexmedetomidine in humans. II. Hemodynamic changes
-
Bloor B.C., Ward D.S., Belleville J.P., et al. Effects of intravenous dexmedetomidine in humans. II. Hemodynamic changes. Anesthesiology 77 6 (1992) 1134-1142
-
(1992)
Anesthesiology
, vol.77
, Issue.6
, pp. 1134-1142
-
-
Bloor, B.C.1
Ward, D.S.2
Belleville, J.P.3
-
42
-
-
0033811109
-
Influence of cardiac output on dexmedetomidine pharmacokinetics
-
Dutta S., Lal R., Karol M.D., et al. Influence of cardiac output on dexmedetomidine pharmacokinetics. J Pharm Sci 89 4 (2000) 519-527
-
(2000)
J Pharm Sci
, vol.89
, Issue.4
, pp. 519-527
-
-
Dutta, S.1
Lal, R.2
Karol, M.D.3
-
43
-
-
0037302179
-
A phase II study to evaluate the efficacy of dexmedetomidine for sedation in the medical intensive care unit
-
Venn M., Newman J., and Grounds M. A phase II study to evaluate the efficacy of dexmedetomidine for sedation in the medical intensive care unit. Intensive Care Med 29 2 (2003) 201-207
-
(2003)
Intensive Care Med
, vol.29
, Issue.2
, pp. 201-207
-
-
Venn, M.1
Newman, J.2
Grounds, M.3
-
44
-
-
4344614342
-
Dexmedetomidine as a total intravenous anesthetic agent
-
Ramsay M.A., and Luterman D.L. Dexmedetomidine as a total intravenous anesthetic agent. Anesthesiology 101 3 (2004) 787-790
-
(2004)
Anesthesiology
, vol.101
, Issue.3
, pp. 787-790
-
-
Ramsay, M.A.1
Luterman, D.L.2
-
45
-
-
2442584848
-
Sedation during mechanical ventilation in infants and children: dexmedetomidine versus midazolam
-
Tobias J.D., and Berkenbosch J.W. Sedation during mechanical ventilation in infants and children: dexmedetomidine versus midazolam. South Med J 97 5 (2004) 451-455
-
(2004)
South Med J
, vol.97
, Issue.5
, pp. 451-455
-
-
Tobias, J.D.1
Berkenbosch, J.W.2
-
46
-
-
0037379486
-
Prolonged dexmedetomidine infusion as an adjunct in treating sedation-induced withdrawal
-
Multz A.S. Prolonged dexmedetomidine infusion as an adjunct in treating sedation-induced withdrawal. Anesth Analg 96 4 (2003) 1054-1055
-
(2003)
Anesth Analg
, vol.96
, Issue.4
, pp. 1054-1055
-
-
Multz, A.S.1
-
47
-
-
22144448567
-
Prospective evaluation of dexmedetomidine for noninvasive procedural sedation in children
-
Berkenbosch J.W., Tobias J.D., and Wankum P.C. Prospective evaluation of dexmedetomidine for noninvasive procedural sedation in children. Pediatric Critical Care Medicine 6 4 (2005) 435-439
-
(2005)
Pediatric Critical Care Medicine
, vol.6
, Issue.4
, pp. 435-439
-
-
Berkenbosch, J.W.1
Tobias, J.D.2
Wankum, P.C.3
-
48
-
-
0031668941
-
Reversal of the sedative and sympatholytic effects of dexmedetomidine with a specific alpha2-adrenoceptor antagonist atipamezole: a pharmacodynamic and kinetic study in healthy volunteers
-
Scheinin H., Aantaa R., Anttila M., et al. Reversal of the sedative and sympatholytic effects of dexmedetomidine with a specific alpha2-adrenoceptor antagonist atipamezole: a pharmacodynamic and kinetic study in healthy volunteers. Anesthesiology 89 3 (1998) 574-584
-
(1998)
Anesthesiology
, vol.89
, Issue.3
, pp. 574-584
-
-
Scheinin, H.1
Aantaa, R.2
Anttila, M.3
-
49
-
-
0038148127
-
Development of bradycardia during sedation with dexmedetomidine in an infant concurrently receiving digoxin
-
Berkenbosch J.W., and Tobias J.D. Development of bradycardia during sedation with dexmedetomidine in an infant concurrently receiving digoxin. Pediatr Crit Care Med 4 2 (2003) 203-205
-
(2003)
Pediatr Crit Care Med
, vol.4
, Issue.2
, pp. 203-205
-
-
Berkenbosch, J.W.1
Tobias, J.D.2
|